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中国农学通报 ›› 2012, Vol. 28 ›› Issue (35): 1-5.

• 畜牧 动物医学 蚕 蜂 •    下一篇

大肠杆菌病的噬菌体治疗

马艳香 王元超 任慧英   

  • 收稿日期:2012-07-12 修回日期:2012-08-23 出版日期:2012-12-15 发布日期:2012-12-15
  • 基金资助:

    山东省自然科学基金“大肠杆菌多价噬菌体尾丝蛋白结构与功能研究”

Phage Therapy of Colibacillosis

  • Received:2012-07-12 Revised:2012-08-23 Online:2012-12-15 Published:2012-12-15

摘要:

近年来,由于抗生素的滥用,致使耐药菌株越来越多,新的抗生素的研制又存在周期长、花费高、使用后细菌很快产生耐药性等问题,严重限制了抗生素在细菌病治疗中的应用。噬菌体作为天然抗菌剂,可抵制细菌感染,无论是裂解来自人类、动物体中的细菌,抑或消除食品及公共环境领域的污染,噬菌体均扮演着重要的角色。本研究以大肠杆菌感染的噬菌体治疗为例,介绍噬菌体临床治疗方面的研究进展。

关键词: 遗传倾向, 遗传倾向

Abstract:

In recent years, the resistant bacteria increased dramatically due to the abuse of antibiotics. The researches on new antibiotics faced many problems, such as prolonged development process, high cost, resistance of the bacteria appeared quickly after antibiotics coming into markets and so on, which have seriously limited the application of antibiotics in the treatment of the bacterial diseases. As a kind of natural antiseptic, phages play an important role in the bacteriolysis to the bacteria from human, animal, food or environment. This paper was reviewed on the issue of phage therapy of colibacillosis.

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