An update on equine post‐operative ileus: Definitions,pathophysiology and management |
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| Authors: | Z M Lisowski R S Pirie A T Blikslager D Lefebvre D A Hume N P H Hudson |
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| Affiliation: | 1. The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, UK;2. Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, USA;3. Mater Research, The University of Queensland, Woolloongabba, Queensland, Australia |
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| Abstract: | Post‐operative ileus (POI) is a serious condition which any horse undergoing abdominal surgery is at risk of developing, leading to increased hospitalisation time and resulting costs. Advances in the understanding of the development of equine POI are mainly based on human and rodent literature, where manipulation‐induced inflammation has been identified as a trigger, with activation of resident muscularis externa macrophages playing a crucial role in the pathophysiology. Despite many pharmacological trials in all species, there is no single completely successful treatment for POI, highlighting that the condition is multifactorial in cause and requires a multimodal approach to minimise its incidence. |
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| Keywords: | horse colic surgery POI abdomen gastrointestinal motility |
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