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Description of a regional anaesthesia technique for the dorsal cranium in the dog: a cadaveric study
Yishai Kushnir Gal S. Marwitz Yael Shilo-Benjamini Joshua Milgram 《Veterinary anaesthesia and analgesia》2018,45(5):684-694
Objective
To identify landmarks and to describe a technique for nerve blockade of the dorsal cranium in dogs.Study design
Anatomic cadaveric study.Animals
A total of 39 dog cadavers, weighing 18.0 ± 9.7 kg (mean ± standard deviation).Methods
The study was performed in three parts. In the initial part, cadavers were dissected to determine the location of the frontal, zygomaticotemporal, and major occipital nerves, and to identify prominent landmarks for their blockade. In the second part, one technique was developed to block each of the frontal and zygomaticotemporal nerves, and two techniques, rostral and caudal, were developed to block the major occipital nerve. Injection solution was 0.05% methylene blue in 0.5% bupivacaine. In the third part, cadavers were used to test the techniques developed in the second part with 0.04 mL kg?1 of the same injectate administered at each site (maximal volume 0.5 mL per site). The length of nerve stained was measured, with a length ≥6 mm considered successful. Confidence intervals were calculated using Fisher’s exact test.Results
Success rates (95% confidence interval) for the frontal, zygomaticotemporal, and rostral and caudal locations for the major occipital nerve were 94% (80–99%), 91% (76–98%), 74% (58–86%) and 77% (59–89%), respectively. With a combination of both locations, the success rate for the major occipital nerve was 100% (90–100%).Conclusion and clinical relevance
This study describes a simple regional anaesthesia technique using palpable anatomical landmarks that may provide analgesia for dogs undergoing craniotomy. 相似文献9.
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Woodie JB Ducharme NG Hackett RP Erb HN Mitchell LM Soderholm LV 《Equine veterinary journal》2005,37(5):425-429
REASONS FOR PERFORMING STUDY: Dorsal displacement of the soft palate (DDSP) is a common condition in racehorses for which various surgical treatments are often performed. In light of recent findings that suggested the position of the larynx may influence the occurrence of DDSP, we investigated whether a noninvasive mean of affecting the position of the larynx could be effective in the management of DDSP. HYPOTHESIS: An external device (laryngohyoid support; LHS) positioning the larynx in a more rostral and dorsal location and preventing caudal displacement of the basihyoid bone would be effective in preventing DDSP during strenuous exercise. METHODS: Ten horses were exercised on a high-speed treadmill under 4 different treatment conditions: control (n = 10); control with external device (n = 10); after bilateral resection of thyrohyoid (TH) muscles (n = 7); and after bilateral resection of TH muscles with external device (n = 7). Two trials were performed randomly for each of the 4 conditions. In Trial 1, videoendoscopic images of the upper airway, pharyngeal and tracheal static pressures, and arterial blood gases were collected. In Trial 2, airflow measurement combined with mask and tracheal static pressure was obtained, and upper airway impedance calculated. The trials allowed calculation of airway impedance and respiratory frequency, and assessment of ventilation using arterial PO2 and PCO2. RESULTS: Under control conditions, none of the 10 horses developed DDSP. There was no statistically significant effect from the LHS on airway impedance or respiratory frequency, nor on arterial PO2 and PCO2. Seven of the 10 horses developed DDSP during exercise after resection of the TH muscles. None of these 7 horses continued to experience DDSP during exercise with the external device. In the latter group and condition, the LHS significantly improved inspiratory and expiratory flow and impedance. CONCLUSIONS: The LHS helped prevent experimentally induced DDSP at exercise, probably by statically positioning the larynx in a more rostral and dorsal position. POTENTIAL RELEVANCE: Field studies are required to investigate whether the LHS can successfully prevent DDSP in horses with naturally occurring disease. 相似文献
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1. The effects of egg turning upon the formation of sub‐embryonic fluid (SEF), and albumen weight and composition are described up to day 8 of incubation.
2. The density of albumen increased, and the density of yolk sac contents decreased, during the first 5 d of incubation. Failure to turn eggs diminished these changes.
3. The rate of formation of SEF and its maximum weight were lower if eggs were not turned, as was the rate of decrease in albumen weight.
4. The concentration of sodium and chloride, as well as osmolality, were higher in SEF than in thin albumen, and were affected by a failure to turn eggs.
5. Static incubation altered the concentrations of yolk nutrients in SEF.
6. It is concluded that the formation of SEF is primarily dependent upon the transfer of sodium and chloride from albumen to SEF so creating an osmotic force for water movement in the same direction. Turning the eggs promotes this process by ensuring an adequate supply of ions in thin albumen adjacent to the blastoderm. 相似文献
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Glaucoma and inherited retinal degeneration/dystrophy are leading causes of blindness in veterinary patients. Currently, there is no treatment for the loss of vision that characterizes both groups of diseases. However, this reality may soon change as recent advances in understanding of the disease processes allow researchers to develop new therapies aimed at preventing blindness and restoring vision to blind patients. Elucidating the molecular mechanisms of retinal ganglion cell death in glaucoma patients has led to the development of neuroprotective drugs which protect retinal cells and their function from the disastrous effects of elevated pressure. Identification of the genetic mutation responsible for inherited degenerations and dystrophies of the outer retina has enabled researchers using gene therapy to restore vision to blind dogs. Other patients may benefit from retinal transplantation, stem cell therapy, neuroprotective drugs, nutritional supplementation and even retinal prostheses. It is possible that soon it will be possible to restore sight to some blind patients. 相似文献
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Selecting 6 heads of new yak strains(the offspring of reciprocal cross of F1 produced by wild yak male mated with domestic yak female)and 6 domestic yaks at 3 and 12 age in months respectively at Datong Yak Farm of Qinghai Province. This paper was studied for the morphological characteristics of the skin and hair coat of yak and their adaptability to the cold living environment in Qinghai-Tibetan plateau. The results indicated that it should be of vital importance marker for the morphological characteristics of the skin and hair coat with two type of yaks at 3 and 12 age in months and their regulations of growth and development to adapt to the cold living environment in Qinghai-Tibetan plateau,The main morphological indexes of the skin and hair coat of the rearing new yak strain were higher than those of the domestic yaks at the same age in months, or speak precisely, the new yak strain was more powerful adaptable to the alpine cold living environment than that of the domestic yaks. The resvlts above provided scientific basis for the native strain breeding of yak and the new yak strain rearing. 相似文献
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The expression pattern of several intermediate-filament proteins (vimentin, cytokeratin 8, 18 and 19) and the basal lamina component laminin was investigated in the Wolffian and the Müllerian ducts of bovine embryos and fetuses. The material studied comprised sexually undifferentiated stages [crown-rump length (CRL) 0.9 cm/1.0 cm/1.2 cm/1.9 cm/2.5 cm] and female stages (CRL 3.0 cm/4.2 cm/5.1 cm). Laminin could be demonstrated in the basal lamina of the developing Wolffian and Müllerian duct as well as in the stroma surrounding the Müllerian duct. The intermediate-filament protein vimentin was expressed in the mesothelium of the funnel field and in the epithelium of the Müllerian duct in all studied specimens, whereas the epithelial cells of the Wolffian duct only showed vimentin expression from a CRL of 2.2 cm onwards. In the cranial part of the Müllerian ducts only a few cells stained with pan-cytokeratin antibodies, whereas mesothelium and epithelium of the Wolffian duct showed as distinct immunostaining in all investigated stages. Both genital ducts showed no immunostaining with the antibody against cytokeratin 19 at any time of development. We conclude from our immunohistochemical results that the epithelial cells of the Wollfian duct do not contribute cells to the developing Müllerian duct. 相似文献
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Katharina Thieme Luis Mesquita Simona Lieberth Christian Dancker Marcus Georg Doherr Johanna Corinna Eule 《Veterinary ophthalmology》2023,26(2):135-144