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1.
The ethanol extract and fractions from Coccoloba acrostichoides aerial parts were assayed for in vitro antimicrobial activity. The extract was active against the assayed bacteria while most of the fractions also inhibited fungal growth, especially the n-hexane and EtOAc fractions. The isolated beta-sitosterol and betulin were tested, being the last one active against Fusarium oxysporum. 相似文献
2.
Activity-guided fractionation of the methanol extract of Ebenus pinnata aerial parts led to the isolation of ombuoside (1), kaempferol 3-O-rutinoside (2), rutin (3), catechin (4), and picein (5), along with beta-sitosterol and beta-sitosterol glucoside. Compounds 1-4 showed significant antioxidant activity in the DPPH, and TEAC, reducing power assays. 相似文献
3.
Cytotoxic constituents from Plumbago zeylanica 总被引：5，自引：0，他引：5
Nguyen AT Malonne H Duez P Vanhaelen-Fastre R Vanhaelen M Fontaine J 《Fitoterapia》2004,75(5):500-504
The bioassay-guided fractionation of the dichloromethane extract of aerial parts of Plumbago zeylanica led to the isolation of beta-sitosterol, beta-sitosteryl-3beta-glucopyranoside, beta-sitosteryl-3beta-glucopyranoside-6'-O-palmitate (1), lupenone, lupeol acetate, plumbagin and trilinolein. Compound 1 showed cytotoxic activity against MCF7 and Bowes cancer cell lines (IC50 113 microM and 152 microM, respectively), beta-sitosterol inhibited Bowes cell growth (IC50 36.5 microM) and plumbagin was cytotoxic against MCF7 and Bowes cells (IC50 1.28 microM and 1.39 microM, respectively). 相似文献
4.
The crude ethanol extract from the leaves of Zanthoxylum liebmannianum exhibited inhibitory effect on the reproduction of trophozoites of Entamoeba histolytica (IC(50)=3.48 microg/ml) and Giardia lamblia (IC(50)=58.00 microg/ml). From this extract, asarinin, hyperin, beta-sitosterol, and beta-sitosterol glucoside were isolated. Among them, asarinin was the most active with IC(50) values of 19.86 microg/ml for E. histolytica and 35.45 microg/ml for G. lamblia. The remaining compounds showed moderate activity against both parasites. 相似文献
5.
The leaves of Calotropis procera yielded an organic carbonate (1), along with stigmasterol and beta-sitosterol, identified by spectroscopic methods. 相似文献
6.
The stems of Hedychium villosum yielded the new diterpenoid 1, named villosin, along with coronarin E and beta-sitosterol. Their structures were elucidated by spectroscopic methods including mono- and bi-dimensional NMR. 相似文献
7.
The isolation of lupeol, beta-sitosterol acetate and three quinolizidinic alkaloids, (+)-lupanine, (-)-sparteine and (-)-3 beta-hydroxy-13 alpha-tigloyloxy-lupanine (1), from the stem bark of Ormosia wayana is reported. 相似文献
8.
Diterpenoids from Isodon japonica 总被引：6，自引：0，他引：6
A new ent-kaurane diterpenoid maoyecrystal F (1) and its acetonide derivative (2), together with seven known compounds, lasiodonin, maoyerabdosin, odonicin, enmenin, oridonin, beta-sitosterol and daucosterol, were isolated from the leaves of Isodon japonica. 相似文献
9.
Two prenylated isoflavanones (1) and (2) were isolated from the stem bark of Lespedeza bicolor along with the known compounds ethyl caffeate, caffeic acid, protocatechuic acid, betulinic acid, betulin, beta-sitosterol and from the stem heartwood daidzein and isoliquiritigenin. 相似文献
10.
An anti-inflammatory principle from cactus 总被引：1，自引：0，他引：1
In previous studies, the ethanol extract of cactus (Opuntia ficus-indica) showed potent anti-inflammatory action. In the present study, following fractionation of the methanol extract of cactus stems guided by adjuvant-induced chronic inflammation model in mice, an active anti-inflammatory principle has been isolated and identified as beta-sitosterol. 相似文献
11.
A new secoiridoid glycoside from Lonicera angustifolia 总被引：3，自引：0，他引：3
A new secoiridoid glycoside, 6'-O-beta-apiofuranosylsweroside (1), together with the known compounds sweroside, loganin, beta-sitosterol, oleanolic acid, ursolic acid and methyl-4-hydroxy benzoate have been identified from the leaves of Lonicera angustifolia. The structure of the new compound has been elucidated on the basis of spectroscopic and chemical evidence. 相似文献
12.
Ursene type nortriterpene from Debregeasia salicifolia 总被引：1，自引：0，他引：1
A new triterpene, 3beta-19alpha-dihydroxy-30-norurs-12-ene (1), has been isolated from the methanolic extract of Debregeasia salicifolia stems. Its structure has been elucidated with the help of one- and two-dimensional NMR and NOE studies. Lupeol, beta-sitosterol, stigmasterol and oleanolic acid are also reported for the first time from this species. 相似文献
13.
Lotaustralin from Rhodiola rosea roots 总被引：4，自引：0，他引：4
Lotaustralin was isolated as a mixture of two diastereoisomeric forms from the methanol extract of Rhodiola rosea roots, together with the known compounds rosavin, rosarin, rosin, rosiridin, salidroside, and beta-sitosterol. The structure of lotaustralin was established by 1D and 2D-NMR spectroscopy, including 1H-1H COSY, NOESY, HMQC, and HMBC, and FAB and HR MS. 相似文献
14.
Matos MF Leite LI Brustolim D de Siqueira JM Carollo CA Hellmann AR Pereira NF da Silva DB 《Fitoterapia》2006,77(3):227-229
The cytotoxic effects of seven constituents isolated from Duguetia glabriuscula were evaluated against Hep2 human larynx carcinoma cells. The cytotoxicity exhibited by beta-sitosterol was as strong as that of cis-platin. (+)-Alloaromadendran-10,14beta-diol caused inhibition of cellular growth with IC50 values lower than 25 microg/ml, a feature that was considered as revealing significant activity. Polycarpol showed borderline cytotoxicity, whereas the other compounds were inactive. 相似文献
15.
Fractions prepared from the methanol extract of Buchholzia coriacea stem bark exhibited a high concentration-dependent antibacterial and antifungal activity compared to the standard antibiotics, ampicillin and tioconazole. In the brine shrimp lethality (BSL) assay, the methanol extract was found to be non-toxic with an LC(50) of 1031 microg/ml. The two main compounds present in the most active fraction were isolated and identified as lupeol and beta-sitosterol. 相似文献
16.
Constituents of Gnetum montanum 总被引：3，自引：0，他引：3
A new stilbene, gnetifolin M (1), was isolated from the lianas of Gnetum montanum, together with seven known compounds, resveratrol (2), gnetol (3), 4', 5,7-trihydroxy-3'-methoxyflavone, beta-sitosterol, daucosterol, ursolic acid, and tetracosanoic acid. The structure of 1 was determined to be 2-(5'-methoxy-3'-hydroxyphenyl)-4-hydroxybenzofuran on the basis of spectroscopic evidence. 相似文献
17.
Rauter AP Filipe MM Prata C Noronha JP Sampayo MA Justino J Bermejo J 《Fitoterapia》2005,76(5):433-438
Diacronema sp. was cultured and its sterols were separated by column chromatography on silica gel. The new sterol 24-ethyl-4alpha-methyl-cholestane-3,20-diol (1) was characterised by NMR and MS spectrometry, as well as (22E)-24-ethyl-4alpha-methyl-5alpha-cholest-22-en-3beta-ol (2) and beta-sitosterol, the major components of the sterol fractions. Neither the biosynthetic origin of the new dihydroxysterol nor its role in the biochemistry of Diacronema is known. 相似文献
18.
Neutral lipids were analyzed in stem wood of a 7-year-old clone and in five 35-70-year-old mature trees of silver birch (Betula pendula Roth). In young trees and in mature wood of old trees, the free fatty acid fraction comprised less than 5% of the concentration of triacylglycerols (TG). The concentration of free linoleic acid was lowest in March when the young trees were dormant and highest during midsummer and September. In mature trees, the TG concentration increased toward the pith, indicating that living parenchyma cells close to the pith have a large TG storage capacity. The TG concentration (mean 0.51 +/- 0.02% of wood dry mass) remained constant throughout the year in young trees, whereas the concentration of beta-sitosterol, the dominant free sterol (mean 82.5 +/- 0.4% of total free sterols), decreased during spring and early summer when the temperature gradually increased, and increased during autumn when the trees became dormant. In young trees, we detected a seasonal interconversion between the free and esterified forms of beta-sitosterol and campesterol, and within the steryl ester fraction between squalene and betulaprenol-7. The concentration of esterified sterols/isoprenoids was exceptionally high, especially in the inner regions of mature stem wood (mean 0.6 +/- 0.03% of wood dry mass). No heartwood formation was detected. 相似文献
19.
Our study focuses on predicting the ultimate short-term load carrying capacity of timber-to-timber connections with dowel-type fasteners. The wide range of possible configurations in practice makes the resolution of these values by tests unrealistic. Moreover, different current regulations do not consider some specific failure mechanisms. In many countries, the reduction of resistance involved by this phenomenon is taken into account by considering an effective number of dowels (nef) smaller than the actual number of dowels (n) in the connection. However, these different regulations disagree on the values of nef and on other points (spacing, partial coefficient of security, formulas). These discrepancies in design rules invite the fundamental research on this topic and, therefore, new methods are sought in order to estimate the load carrying capacities of the connections. In the light of these, our approach consists of predicting the load carrying capacity with the neural network numerical tool. The results obtained by this analysis tool are satisfactory, although the model remains complex. Subsequently, we focus on the simplification of this numerical model with classical regression techniques in order to implement it in a design code. 相似文献
20.
Ophiostoma species were isolated from bark beetles and Abies mariesii, A. veitchii and A. homolepis attacked by the beetles in Nikko, Tochigi, central Honshu, Japan. One to two Ophiostoma species were frequently isolated from each species of bark beetle. Ophiostoma subalpinum was the most common associate of Cryphalus montanus. Ophiostoma sp. B as well as O. subalpinum was a common fungus associated with Polygraphus proximus. Ophiostoma europhioides was isolated from Dryocoetes hectographus and D. autographus as one of the common associates. Ophiostoma sp. J and Ophiostoma sp. S were frequently isolated from D. autographus and D. striatus, respectively. These fungi seem to have specific relationships with particular bark beetles. Ophiostoma sp. B, Ophiostoma sp. J and Ophiostoma sp. S have unique morphological characteristics and appear to be new species. Five trees of A. veitchii, approximately 43 years old, were inoculated with five Ophiostoma species to assess the relative virulence of the fungi. Ophiostoma subalpinum, Ophiostoma sp. B, and O. europhioides had relatively higher virulence than the other species studied. 相似文献