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目的探讨超声高精细血流成像联合弹性成像技术对小乳癌诊断的符合率。方法选取直径小于2.0 cm的乳腺结节女性患者90例,以检查时间为序,按数字表法随机分为观察组和对照组各45例。观察组在二维超声检查的基础上联合高精细血流成像及弹性成像技术对乳腺结节的性质进行分析判断。对照组采用常规二维超声及彩色多普勒超声对乳腺结节的性质特征进行分析判断。以术后病理结果作为标准,比较2组检测方法对乳腺小结节性质诊断的符合率。结果观察组45例,超声诊断良性者39例、恶性6例,与术后病理诊断符合率为97.8%;对照组45例,超声诊断良性者37例、恶性8例,与术后病理诊断符合率为86.7%。观察组诊断符合率与对照组比较差异有统计学意义(P0.05)。结论相较于二维超声及彩色多普勒超声诊断小乳癌,超声高精细血流成像技术联合弹性成像技术诊断符合率更高。 相似文献
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二维结合彩色多普勒超声对诊断乳腺肿块的价值 总被引：1，自引：1，他引：0
目的探讨二维及彩色多普勒超声(CDFI)对乳腺肿块鉴别诊断的价值。方法120例女性患者,术前应用二维超声观察乳腺肿块的大小、形态、位置、边界、包膜、内部回声;采用CDFI检测肿块周边及内部的血流形态、特点,并将彩色血流分为0~Ⅲ级。结果超声诊断乳腺肿块检出率为100%,良、恶性肿瘤超声诊断符合率分别为88.5%、85.7%。良性肿瘤多表现为边界光滑,侧缘回声减弱,CDFI血流分级以Ⅰ~Ⅱ级为主;恶性肿瘤多表现为形态不规则,边界不清,内部回声不均,CDFI血流分级以Ⅱ~Ⅲ级为主。恶性组的收缩期峰值流速(Vmax)、阻力指数(RI)、搏动指数(PI)分别为(28.2±7.3)cm/s、(0.78±0.09)、(1.8±0.3),良性组则分别为(13.5±6.7)cm/s、(0.63±0.07)、(1.2±0.2),差异均有统计学意义(P<0.01)。结论二维超声联合CDFI在乳腺良恶性肿瘤的鉴别诊断中有较高的应用价值。 相似文献
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目的探讨彩色多普勒血流显像(CDFI)对甲状腺肿瘤及单发性结节性甲状腺肿(以下简称结甲肿)诊断的意义。方法比较49例甲状腺癌、126例甲状腺瘤和82例单发性结节甲状腺肿患者的二维及CDFI声像结果。结果(1)二维声像图:结甲肿组与甲癌组比较,其中甲状腺大小、结节大小和血流分级差异均有显著性(P<0.01),而结节内部回声、边缘晕环差异则无显著性(P>0.05);结甲肿组与腺瘤组比较,其甲状腺大小、结节内部回声差异均无显著性(P>0.05),而边缘晕环、血流分级差异则均具显著性(P<0.01)。(2)CDFI:结甲肿组与甲癌组比较,其结节内部Vmax(血流高峰值)、Vmin(血流低峰值)和RI(阻力指数)差异均有显著性(P<0.05),结节周边血流高峰值Vmax、血流低峰值Vmin差异也有显著性(P<0.001),而阻力指数RI差异无显著性(P>0.05);结甲肿组与腺瘤组比较,其结节内部血流高峰值Vmax、血流低峰值Vmin差异无显著性(P<0.05),阻力指数RI差异具显著性(P<0.01);结节周边血流高峰值Vmax、血流低峰值Vmin差异具显著性(P<0.001),阻力指数RI差异无显著性(P>0.05)。结论可以通过单发性结节甲状腺肿患者的二维及CDFI结果进行鉴别诊断。 相似文献
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目的比较MRI动态增强成像(DCE-MRI)及超声(US)在乳腺良恶性病变中的诊断价值。方法回顾性分析105例乳腺病变患者的影像学资料,均行DCE-MRI及US检查。按照美国放射学会推荐的"乳腺影像报告和数据系统"(BI-RADS)进行分类,以术后病理诊断为金标准,应用受试者工作特征曲线(ROC)评价两种检查方法及联合检测的诊断效能。结果 105例患者共检出125个病灶,病理诊断良性病变52例(41.6%),恶性病灶73例(58.4%)。以BI-RADS分级4类以上为检查阳性,4类以下为阴性,DCE-MRI对恶性病变诊断的准确率高于US(94.4%vs 76.7%,P=0.043);DCE-MRI对良性病变诊断的准确率与US比较差异无统计学意义(82.7%vs 88.5%,P=0.578);DCE-MRI、US及联合检测的ROC曲线下面积分别为0.915、0.849和0.938(P0.001),联合检测的灵敏度、特异度均高于单项检查(97.3%vs 90.4%vs 76.7%和72.3%vs 69.3%vs 84.5%,P0.05)。结论 MRI动态增强成像及超声在乳腺良恶性病变的诊断中准确率均较高,二者联合应用优于单一检查方法。 相似文献
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《河北北方学院学报(自然科学版)》2017,(12)
目的探讨实时剪切波弹性成像技术在甲状腺结节分析和判定中的诊断价值。方法对80例甲状腺结节患者(108个结节)行常规超声扫查后,对结节行剪切波弹性成像,得到相应的杨氏模量均值、杨氏模量最大值、杨氏模量最小值。结果病理诊断108个甲状腺结节,良性36个,恶性72个。甲状腺良、恶性结节的最大杨氏模量值分别为(47.52±19.76)kPa和(83.65±29.36)kPa(P0.05);平均杨氏模量值分别为(37.27±20.37)kPa和(64.37±28.62)kPa(P0.05)。结论甲状腺恶性结节的杨氏模量最大值与平均值明显高于良性结节,实时剪切波弹性成像技术有助于甲状腺结节良恶性的鉴别诊断。 相似文献
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目的 分析超声与核磁共振(MRI)在诊断乳腺良性和恶性病变的临床应用价值.方法 使用超声及MRI检查68例患者的73个乳腺肿块,并与术后病理活检结果相比较.结果 68例经病理活检诊断:恶性病灶30个,良性病灶43个.其中恶性病灶与良性病灶的MRI曲线类型的差异有统计学意义(P＜0.01).与病理活检诊断结果比较,超声诊断的敏感度为83.3％,特异度为86.0％,准确度为84.9％;MRI诊断的敏感度为93.3％(28/30),特异度为93.0％(40/43),准确度为93.2％(68/73).结论 彩色多普勒超声检测具有简便、直观、价廉的优点,而MRI增强扫描比彩色多普勒超声检查具有更高的敏感度、特异度及准确度,可降低误诊的发生率. 相似文献
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目的分析实时弹性成像(UE)对乳腺肿瘤良恶性的诊断意义。方法对234例发现乳腺肿瘤女性患者的264个病灶进行UE检查及病理活检复检,比较经UE检查的评分与病理活检检测结果的差异。结果 264个病灶中,经UE检查诊断为恶性肿瘤97例,良性肿瘤167例;病理检查诊断为恶性肿瘤100例,良性肿瘤164例,两者的诊断结论差异无统计学意义(?2=0.073,P>0.05);UE检查诊断乳腺肿瘤的总符合率为96.6%,其中诊断良性乳腺肿瘤的符合率为98.2%,诊断恶性乳腺肿瘤的符合率为94.0%。结论 UE技术有助于乳腺肿瘤良恶性的鉴别诊断。 相似文献
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目的应用BI-RADS分级,探讨彩色多普勒超声与X线钼靶对鉴别乳腺肿块的良恶性的价值。方法应用彩色多普勒超声与X线钼靶成像对300例共356个乳腺病灶进行检查,利用BI-RADS分级诊断标准进行评估,并与病理结果作对比。结果彩色多普勒超声诊断乳腺肿块恶性病变的敏感性为84.6%（126/149）,特异性为85.0%（176/207）,准确性为85.1%（303/356）;X线钼靶诊断乳腺肿块恶性病变的敏感性为86.6%（129/149）,特异性为84.1%（174/207）,准确性为85.1%。（303/356）;两种方法的敏感性、特异性和准确性比较差异均无统计学意义（P〉0.05）。Kappa一致性分析结果为：K=0.9768（〉0.75）,高度一致。结论彩色多普勒超声与X线钼靶检查应用BI-RADS分级诊断乳腺肿块具有重要的临床价值,两种方法的检测结果具有高度一致性。 相似文献
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Rosencwaig A 《Science (New York, N.Y.)》1982,218(4569):223-228
Thermal features on and beneath the surface of a sample can be detected and imaged with a thermal-wave microscope. Various methodologies for the excitation and detection of thermal waves are discussed, and several applications, primarily in microelectronics, are presented. 相似文献
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Progress has recently been made in implementing magnetic resonance imaging (MRI) techniques that can be used to obtain images in a fraction of a second rather than in minutes. Echo-planar imaging (EPI) uses only one nuclear spin excitation per image and lends itself to a variety of critical medical and scientific applications. Among these are evaluation of cardiac function in real time, mapping of water diffusion and temperature in tissue, mapping of organ blood pool and perfusion, functional imaging of the central nervous system, depiction of blood and cerebrospinal fluid flow dynamics, and movie imaging of the mobile fetus in utero. Through shortened patient examination times, higher patient throughput, and lower cost per MRI examination, EPI may become a powerful tool for early diagnosis of some common and potentially treatable diseases such as ischemic heart disease, stroke, and cancer. 相似文献
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Suenaga K Tence M Mory C Colliex C Kato H Okazaki T Shinohara H Hirahara K Bandow S Iijima S 《Science (New York, N.Y.)》2000,290(5500):2280-2282
Electron energy-loss spectroscopy (EELS) is widely used to identify elemental compositions of materials studied by microscopy. We demonstrate that the sensitivity and spatial resolution of EELS can be extended to the single-atom limit. A chemical map for gadolinium (Gd) clearly reveals the distribution of Gd atoms inside a single chain of metallofullerene molecules (Gd@C82) generated within a single-wall carbon nanotube. This characterization technique thus provides the "eyes" to see and identify individual atoms in nanostructures. It is likely to find broad application in nanoscale science and technology research. 相似文献
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Elachi C Brown WE Cimino JB Dixon T Evans DL Ford JP Saunders RS Breed C Masursky H McCauley JF Schaber G Dellwig L England A Macdonald H Martin-Kaye P Sabins F 《Science (New York, N.Y.)》1982,218(4576):996-1003
The shuttle imaging radar (SIR-A) acquired images of a variety of the earth's geologic areas covering about 10 million square kilometers. Structural and geomorphic features such as faults, folds, outcrops, and dunes are clearly visible in both tropical and arid regions. The combination of SIR-A and Seasat images provides additional information about the surface physical properties: topography and roughness. Ocean features were also observed, including large internal waves in the Andaman Sea. 相似文献
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Weissleder R 《Science (New York, N.Y.)》2006,312(5777):1168-1171
Medical imaging technologies have undergone explosive growth over the past few decades and now play a central role in clinical oncology. But the truly transformative power of imaging in the clinical management of cancer patients lies ahead. Today, imaging is at a crossroads, with molecularly targeted imaging agents expected to broadly expand the capabilities of conventional anatomical imaging methods. Molecular imaging will allow clinicians to not only see where a tumor is located in the body, but also to visualize the expression and activity of specific molecules (e.g., proteases and protein kinases) and biological processes (e.g., apoptosis, angiogenesis, and metastasis) that influence tumor behavior and/or response to therapy. This information is expected to have a major impact on cancer detection, individualized treatment, and drug development, as well as our understanding of how cancer arises. 相似文献
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Mutter JC 《Science (New York, N.Y.)》1992,258(5087):1442-1443
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Beckman M 《Science (New York, N.Y.)》2003,300(5616):76-77
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In situ atomic force microscope observations were made of the adsorption of anions (1- or 2-) of the organic diacid 5-benzoyl-4-hydroxy-2-methoxybenzenesulfonic acid from aqueous solution onto the (0001) surface of hydrotalcite (HT), a layered clay. This adsorption process is believed to mimic the ion-exchange reactions that occur within the layers of HT and other layered clays. Atomic force microscope images of the (0001) surfaces of HT, acquired in aqueous solutions, reveal an ordered structure with respect to magnesium and aluminum atoms. In the presence of the anions, atomic force microscopy indicates pH-dependent adsorption onto the formally cationic HT surface. The anion coverage is governed by electroneutrality and steric interactions between the bulky anions within the adsorbed layer, whereas the orientation of the anions with respect to the HT surface is dictated by coulombic interactions and hydrogen bonding between the anion's sulfonate moiety and clay hydroxyl triads. These observations reveal that the reversible adsorption of molecular species can be examined directly by in situ atomic force microscopy, providing details of surface stoichiometry and adlayer symmetry on the local, molecular level. 相似文献
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Natural pyrrhotites, when studied by high resolution electron microscopy, yield crystallographic information on a unit cell scale. Structural heterogeneity is prominent. The many reported superstructures are interpretable through an antiphase model. The 5C pyrrhotite superstructure results from an ordered sequence of antiphase domains while the higher temperature NC type results from a disordered sequence. 相似文献