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1.
The five‐year value in the compound annual growth rate of the biopesticides sector is predicted to be 16% by 2017 and to produce a global market worth $US 10 billion. Despite this, several impediments occur within the EU that negatively affect biopesticide research and innovation. At present, there are fewer biopesticide‐active substances registered in the EU compared with the United States, India, Brazil and China. The relatively low level of biopesticide research in the EU (6880 ISI papers) versus the United States (18 839), India (9501) and China (7875) relates to the greater complexity of EU‐based biopesticide regulations compared with these other countries. In this light, it is worth noting that tensions may exist between regulators that emphasise the beneficial nature of biopesticides in environmentally friendly crop management and those that adopt a more technologically based approach dependent on a chemical‐pesticide‐driven model. Compared with the other aforementioned countries, far fewer biopesticide products are available in the EU market, mainly as a direct result of the severe regulatory factors present there. The extent to which this trend will continue depends largely on a range of interacting political and/or regulatory decisions that influence environmentally friendly agricultural industries. © 2017 Society of Chemical Industry  相似文献   

2.
The introduction of new food safety regulations in the European Union has resulted in the withdrawal of many synthetic active substances used in plant protection products, in light of their potential or actual harmful effect on human and animal health, as well as on the environment. Alternatives to these compounds are being developed – naturally occurring pesticides, also referred to as biopesticides. The use of biopesticides in crop protection leads to decreased levels of pesticide residues in foods, and as a result to lower risk levels for the consumer. Biologically active agents defined as biopesticides are varied, and therefore application of the same environmental and consumer safety criteria to all of them is impossible. This presents serious complications in the approval of these pesticides as active plant protection products and in their registration. It needs to be stressed that, in the registration procedure of the European Union, biopesticides are subject to the same regulations as synthetic active substances. This situation has resulted in the need to introduce numerous new provisions in the legislation, as well as the preparation of new guidelines facilitating the registration of biopesticides. These activities aim to promote naturally originating pesticides. © 2014 Society of Chemical Industry  相似文献   

3.
Vegetables are one of the important crops which could alleviate poverty and malnutrition among the smallholder farmers in tropical Asia and Africa. However, a plethora of pests limit the productivity of these crops, leading to economic losses. Vegetable producers overwhelmingly rely on chemical pesticides in order to reduce pest‐caused economic losses. However, over‐reliance on chemical pesticides poses serious threats to human and environmental health. Hence, biopesticides offer a viable alternative to chemical pesticides in sustainable pest management programs. Baculoviruses such as nucleopolyhedrovirus (NPV) and granulovirus (GV) have been exploited as successful biological pesticides in agriculture, horticulture and forestry. Maruca vitrata multiple nucleocapsid NPV (MaviMNPV) was found to be a unique baculovirus specifically infecting pod borer on food legumes, and it has been successfully developed as a biopesticide in Asia and Africa. Entomopathogenic fungi also offer sustainable pest management options. Several strains of Metarhizium anisopliae and Beauveria bassiana have been tested and developed as biopesticides in Asia and Africa. This review specifically focuses on the discovery and development of entomopathogenic virus and fungi‐based biopesticides against major pests of vegetable legumes and brassicas in Asia and Africa. © 2019 Society of Chemical Industry  相似文献   

4.
For many years, the emphasis of industry discovery programs has been on finding new target sites of pesticides and finding pesticides that inhibit single targets. There had been an emphasis on genomics in finding single targets for potential pesticides. There is also the claim that registration of single target inhibiting pesticides is simpler if the mode of action is known. Conversely, if one looks at the evolution of resistance from an epidemiological perspective to ascertain which pesticides have been the most recalcitrant to evolutionary forces, it is those that have multiple target sites of action. Non‐target‐site resistances can evolve to multi‐target‐site inhibitors, but these resistances can often be overcome by structural modification of the pesticide. Industry has looked at pest‐toxic natural products as pesticide leads, but seems to have abandoned those where they can find no single target of action. Perhaps nature has been intelligent and evolved many natural products that are synergistic multi‐target‐site inhibitors, and that is why natural compounds have been active for millennia? We should be learning from nature while combining new chemistry technologies with vast accrued databases and computer aided design allowing fragment‐based discovery and scaffold hopping to produce multi‐target site inhibitors instead of single target pesticides. © 2019 Society of Chemical Industry  相似文献   

5.
Natural products that have been used commercially as crop protection agents   总被引:4,自引:0,他引:4  
Many compounds derived from living organisms have found a use in crop protection. These compounds have formed the basis of chemical synthesis programmes to derive new chemical products; they have been used to identify new biochemical modes of action that can be exploited by industry-led discovery programmes; some have been used as starting materials for semi-synthetic derivatives; and many have been used or continue to be used directly as crop protection agents. This review examines only those compounds derived from living organisms that are currently used as pesticides. Plant growth regulators and semiochemicals have been excluded from the review, as have living organisms that exert their effects by the production of biologically active secondary metabolites.  相似文献   

6.
Agricultural industrialization and the subsequent reliance on pesticides has resulted in numerous unintended consequences, such as impacts upon the environment and by extension human health. Eco‐efficiency is a strategy for sustainably increasing production, while simultaneously decreasing these externalities on ecological systems. Eco‐efficiency is defined as the ratio of production to environmental impacts. It has been widely adopted to improve chemical production, but we investigate the challenges of applying eco‐efficiency to pesticide use. Eco‐efficiency strategies include technological innovation, investment in research and development, improvement of business processes, and accounting for market forces. These components are often part of integrated pest management (IPM) systems that include alternatives to pesticides, but its implementation is often thwarted by commercial realities and technical challenges. We propose the creation and adoption of an eco‐efficiency index for pesticide use so that the broad benefits of eco‐efficient strategies such as IPM can be more readily quantified. We propose an index based upon the ratio of crop yield to a risk quotient (RQ) calculated from pesticide toxicity. Eco‐efficiency is an operational basis for optimizing pest management for sustainability. It naturally favors adoption of IPM and should be considered by regulators, researchers, and practitioners involved in pest management. © 2019 Society of Chemical Industry  相似文献   

7.
With the anticipated population growth in the coming decades, the changing regulatory environment, and the continued emergence of resistance to commercial pesticides, there is a constant need to discover new lead chemistries with novel modes of action. We have established a portfolio of approaches to accelerate lead generation. One of these approaches capitalizes on the rich bioactivity of natural products (NPs), highlighted by the numerous examples of NP‐based crop protection compounds. Within Corteva Agriscience and the affiliated preceding companies, NPs have been a fruitful approach, for nearly three decades, to identifying and bringing to the market crop protection products inspired by or originating from NPs, . Included in these NP‐based crop protection products are the spinosyns family of insecticides, and those from more recent areas of NP‐based fungicidal chemistry, as highlighted in this perspective. © 2019 Society of Chemical Industry  相似文献   

8.
我国有占世界19%的人口,但仅有占世界9%的耕地,因此保证国家粮食安全是头等大事。在确保生态环境安全的前提下,如何增加作物产量和保障农产品质量安全始终是我国农业快速发展面临的一大挑战。在高效、负责、透明的政府能力建设中,我国农业的绿色发展和高质量发展战略,我国农药管理的法制建设、市场监管、食品安全、环境监测、有害生物治理、应用技术服务及推广等都取得了显著进步。到2021年底,我国已经登记了740多个农药有效成分,41 433个农药产品。2021年,全国1 705家农药定点企业,共生产了化学农药原药249.8万t。不仅满足了国内有害生物防控的实际需要,还出口180多个国家和地区,农药出口额达到234亿美金。我国还有的10个高毒农药品种,已经控制在1.3%以下,且安排在未来5年内会陆续退市。本文还分析梳理了今后我国农药管理发展所面临的挑战。  相似文献   

9.
Pest management is facing economic and ecological challenge worldwide due to human and environmental hazards caused by majority of the synthetic pesticide chemicals. Identification of novel effective insecticidal compounds is essential to combat increasing resistance rates. Botanical pesticides have long been touted as attractive alternatives to synthetic chemical pesticides for pest management because botanicals reputedly pose little threat to the environment or to human health. The body of scientific literature documenting bioactivity of plant derivatives to arthropod pests continues to expand, yet only a handful of botanicals are currently used in agriculture in the industrialized world, and there are few prospects for commercial development of new botanical products. Pyrethrum and neem are well established commercially, pesticides based on plant essential oils have entered the marketplace, and the use of rotenone appears to be waning. A number of plant substances have been considered for use as pest antifeedants, repellents and toxicants, but apart from some natural mosquito repellents, a little commercial success has ensued for plant substances that modify arthropod behavior. Several factors appear to limit the success of botanicals, most notably regulatory barriers and the availability of competing products (newer synthetics and fermentation products) that are cost-effective and relatively safe compared with their predecessors. In the context of agricultural pest management, botanical pesticides are best suited for use in organic food production in industrialized countries but can play a much greater role in the production and postharvest protection of food in developing countries. Botanicals have been in use for a long time for pest control. The compounds offer many environmental advantages. However, their uses during the 20th century have been rather marginal compared with other bio-control methods of pests and pathogens. Improvement in the understanding of plant allelochemical mechanisms of activity offer new prospects for using these substances in crop protection. I’m trying in this article to present different kinds of botanical pesticides came from different recourses and their mode of actions as well as I will try to examine the reasons behind their limited use (disadvantages) and the actual crop protection developments involving biopesticides of plant origin for organic or traditional agricultures to keep our environment clean and safer for humankind and animals.  相似文献   

10.
为研究苹果主要病虫害全程生物农药防控效果,2020、2021年在苹果休眠期使用石硫合剂和腐殖酸铜,在生长期选择多种生物农药,包括苦参碱、中生菌素、多抗霉素、大黄素甲醚、枯草芽胞杆菌、苏云金芽胞杆菌和鱼藤酮等,监测了苹果斑点落叶病、褐斑病、苹果黄蚜和苹果小卷叶蛾的发生与为害。结果显示,2020年全程喷施生物农药对苹果斑点落叶病、褐斑病、苹果黄蚜和苹果小卷叶蛾的防治效果最低值分别为82.08%、80.07%、86.04%和86.77%;2021年则分别为87.90%、86.90%、89.67%和88.25%,均接近于化学农药为主的防控区。同时,生物农药防控区未出现任何药害。研究表明苹果全生育期喷施生物农药,可有效控制苹果主要病虫害,对苹果园化学农药减施增效具有重要指导意义。  相似文献   

11.
Summary Weeds cause yield losses and reductions in crop quality. Prior to the introduction of selective herbicides, the drudgery of manual weeding forced farmers to adhere to a suit of weed management tactics by carefully combining crop rotation, appropriate tillage and fallow systems. The introduction of selective herbicides in the late 1940s and the constant flow of new herbicides in the succeeding decades provided farmers with a new tool, ‘the chemical hoe’, putting them in a position to consider weed control more independently of the crop production system than hitherto. The reliance on herbicides for weed control, however, resulted in shifts in the weed flora and the selection of herbicide‐resistant biotypes. In the 1980s, the public concern about side‐effects of herbicides on the environment and human health resulted in increasingly strict registration requirements and, in some countries, political initiatives to reduce the use of pesticides were launched. Today, the number of new herbicides being introduced has decreased significantly and integrated weed management has become the guiding concept. Farmers also have the option of growing herbicide‐resistant crops where the biology of the crop has been adapted to tolerate herbicides considered safe to humans and environmentally benign. This paper discusses some of the recent developments in herbicide discovery, technology and fate, and sketches important future developments.  相似文献   

12.
The seminal work of Stern and his coauthors on integrated control has had a profound and long‐lasting effect on the development of IPM programs in western orchard systems. Management systems based solely on pesticides have proven to be unstable, and the success of IPM systems in western orchards has been driven by conservation of natural enemies to control secondary pests, combined with pesticides and mating disruption to suppress the key lepidopteran pests. However, the legislatively mandated changes in pesticide use patterns prompted by the Food Quality Protection Act of 1996 have resulted in an increased instability of pest populations in orchards because of natural enemy destruction. The management system changes have made it necessary to focus efforts on enhancing biological control not only of secondary pests but also of primary lepidopteran pests to help augment new pesticides and mating disruption tactics. The new management programs envisioned will be information extensive as well as time sensitive and will require redesign of educational and outreach programs to be successful. The developing programs will continue to use the core principles of Stern and his co‐authors, but go beyond them to incorporate changes in society, technology and information transfer, as needed. Copyright © 2009 Society of Chemical Industry  相似文献   

13.
本文论述了农药在现代农业中保障粮食安全的重要作用;分析了农药生产和使用存在的主要问题,以及农药应用风险对粮食安全的负效应;提出了加大农药监控力度,控制和削减化学农药,加快生物农药发展步伐,提高科学使用农药的实施意见。  相似文献   

14.
For registration, the United States Environmental Protection Agency (USEPA) separates pesticides into conventional chemical pesticides and biochemical and microbial pesticides. Natural products generally fall into the latter category. The USEPA has specified the test requirements for registration in the United States in the guidelines for registration of biorational pesticides (Subdivision M of 40 CFR Part 158). A discussion of the regulatory issues requires some reference to the accompanying scientific developments. The potential application of chemicals that affect insect behavior and development appeared an extremely promising approach to the reduction of adverse environmental and health impacts associated with many conventional pesticides. In addition to these benefits, the new biopesticides generally affected a very specific range of target species. However, although juvenile hormones and semiochemicals offer exciting new approaches to pest control, and are potentially valuable components of pest management strategies, acceptance of these techniques has been slow. Commercial development has been difficult for several reasons. Regulatory requirements may appear burdensome. Unconventional pest-control technologies may call for special formulations or application equipment. It may not be easy to establish the efficacy of non-lethal potential techniques. Investigators who derive funds from the public sector may have neither responsibility nor resources to carry the technology beyond the experimental stage. Because most activities in this field have been heavily research-oriented, few workers have possessed the additional resources to obtain safety data or data to satisfy regulatory requirements. Difficulties in preparing and administering guidelines for registration of biopesticides lie in the novelty of the pest control agents and the diversity of the techniques involved in their effective use. Rapid advances in molecular biology and other disciplines continually strain the capabilities of regulators who are responsible for making safety assessments regarding pest-control agents. Although regulatory authorities are familiar with conventional pesticides, safety assessment of biopesticides calls for totally different approaches.  相似文献   

15.
Relatively large amounts of pesticides are needed to control diseases and pests in modern, intensive potato production. Integrated crop management offers a way of reducing the need for pesticides. It aims to reduce costs and improve the quality of the product and of the production methods, while maintaining soil fertility and the quality of the environment. The components of integrated crop management are described. Prevention of diseases and pests has high priority. If diseases or pests are present, non-chemical control methods are preferred and chemical control is based on economic criteria and the monitoring of the soil and crops. The contribution of integrated crop management to the control of two important fungal diseases, late blight (Phytophthora infestans), and stem canker (Rhizoctonia solani) and of one pest, potato cyst nematode (Globodera spp..) is described. The prospects for further development of integrated crop protection are discussed.  相似文献   

16.
J Y Li  X K Guo  Q Zhang  C H Liu  Z H Lin  Z M Yu  H Wu  H B He 《Weed Research》2015,55(5):441-448
Screening crop accessions for allelopathic activity is of paramount importance for crop allelopathy research. Previous bioassays often did not use a mixed culture of donor and target plants, did not use soil and were not conducted under natural conditions. In this study, we designed an inhibitory‐circle method in which a rice accession (donor plant) and Echinochloa crus‐galli (target plant) were cultured together in paddy soil under natural conditions. First, we determined that the highest allelopathic activity of allelopathic rice accession PI312777 was at the 5‐leaf stage, and the suitable distance of rice seedlings and E. crus‐galli was 12 cm apart. This method was then validated by a field test. A further 40 rice accessions were evaluated for allelopathic activity to E. crus‐galli using this method. Two rice accessions, PI312777 and Taichung Native 1, had highly allelopathic activity to E. crus‐galli (inhibitory rate > 50%), while another accession, Lemont, had non‐allelopathic activity. These experimental results were in accordance with previous studies using direct field experiments. The inhibitory‐circle method integrated three necessary conditions, that is donor and target plants grown together, with soil as the medium and under natural conditions for reliable results. The ‘inhibitory‐circle method’, which combined donor and target plants, soil medium and field conditions, can give reliable results in one step, compared with laboratory screening methods. Also, the ‘inhibitory‐circle method’ gave results in 30‐35 days, thereby substantially reducing the requirements for time, labour and cost.  相似文献   

17.
生物农药包括生物化学农药、微生物农药、植物源农药,近年来尽管在整个农药产业中所占的比例还较低,但生物农药总体势头发展良好,且在减少化学农药使用、保障农产品质量安全和生态环境安全及特色农作物的有害生物防控中发挥了重要的积极作用.本文对我国生物农药登记管理的基本情况、产业发展取得的主要成效和当前发展中存在问题等进行了详细梳...  相似文献   

18.
Bacillus thuringiensis (Bt)-based insecticide products constitute the overwhelming majority of biopesticides but, despite having been commercially available for over 30 years, they have made little impact (<1%) on the crop-protection market as a whole. This has been largely due to poor cost-performance factors relative to synthetic organic pesticides. However, recent biotechnological advances—including genetic modification—combined with a variety of emerging opportunities, have created the prospect of the commercialisation of a new range of highly effective Bt-based biopesticides. Bioencapsulation of single-gene products—delta-endotoxins from selected Bt isolates—in killed Pseudomonad cells (Mycogen Corporation's ‘CellCap’ technology), offers a flexible delivery system with enhanced persistence. This versatile approach selects only the most appropriate biotoxins, which can be used to target a number of pest species. It is anticipated that Bt-based pesticides will continue to fill an increasing number of gaps in the panoply of synthetic crop-protection chemicals. Genetically modified products offer advantages in terms of efficacy, flexibility and safety but public concerns regarding perceived risks need to be addressed.  相似文献   

19.
正确认识化学农药的问题   总被引:10,自引:1,他引:10  
屠豫钦 《植物保护》2003,29(4):11-15
针对当前我国农药使用中存在的一些主要问题作了详细地分析,其中有些属于基本概念,应须统一认识,但很多属于农药使用中实际操作如何规范化的问题。文中提出了解决问题的一些建议和措施。  相似文献   

20.
本文介绍并评述了2011-2017年全国农作物重大病虫害防控技术方案要点。这些技术方案主要从贯彻病虫害综合治理原则, 实施重大病虫分区治理、实施联防联控策略, 遵循“节本增效”技术路线, 促进绿色防控技术措施与专业化统防统治融合等方面, 来促进农作物病虫害防控方式的转变和绿色防控技术的推广应用。特别是从增强农田生物多样性入手, 组装配套生态调控措施, 在采用非药剂预防的基础上大力推广保护利用天敌, 减少农药的使用, 实现绿色生态工程控制。  相似文献   

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