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van der Wal GH 《Tijdschrift voor diergeneeskunde》2007,132(8):320; author reply 320-320; author reply 321
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Extract Lymphoedema (LO) is the accumulation of protein-rich interstitial fluid caused by failure of normal lymphatic drainage. Human lymphoedema is classified as primary (congenital hereditary or idiopathic, praecox or tarda forms) or secondary (complication of surgery or radiotherapy, such as that for breast cancer, as well as bancroftian filariasis, cellulitis and lymphangitis amongst others). Primary LO may be due to lymphatic aplasia, hypoplasia, dyspla-sia, lymphangiectasia, or aplasia or hypoplasia of draining lymph nodes. Approximately one in thirty people worldwide has LO. 相似文献
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tic market are the key realm of the Eleventh Five-Year program.As our institution of allocating and balancing fiscal assets,the transfer payment should be perfected in accordance with the public finance.It's necessary to learn from international experiences to adjust the imbalance of fiscal resources and realize the equalization of the public service step by step.transfer payment;Australia;regional development;the view of scientific development0桂海论丛Guihai Tribune33-35F816.11;F812.45J158;2;33;G;J;J158_33;J158_2;杨聪杰;27-29农村金融服务失效的成因及对策分析陈峰燕;南通市委党校 江苏南通226007农村金融;;失效成因;;创新农村金融服务对农民增收具有重要的促进作用。当前,农村经济对金融服务的需求呈现日益扩大及多元化的趋势,但农村金融服务不论是在体制设计,还是在需求的满足程度上,都存在缺陷,已经成为农民增收、农村经济发展、彻底解决“三农”问题的一大制约因素。为此要进行农村金融服务的创新,完善农村金融体系,引导各类金融机构增加对“三农”的支持力度,提高服务效率,为农民增收提供完善的金融服务 相似文献
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Bruce M. Rothschild Robert A. Depalma David A. Burnham Larry Martin 《Anatomia, histologia, embryologia》2020,49(4):571-574
The flat-end surfaces of dinosaur vertebral centra led to the presumption that intervertebral discs occupied the space between their vertebrae. A set of fused hadrosaur vertebrae allowed that hypothesis to be tested. The Tyrannosaurus rex responsible for this pathology did not escape unscathed. It left behind a tooth crown that had fractured. Fragments of that tooth were scattered through the intervertebral space, evidencing that there was no solid structure to impede its movement. That eliminates the possibility of an intervertebral disc and instead proves the presence of an articular space, similar to that in modern reptiles, but at variance to what is noted in birds. While avian cervical vertebral centra appear to be separated by diarthrodial joints, the preponderance of their thoracic vertebral centra is not separated by synovial joints. 相似文献
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Margrethe Therkildsen P. Spleth E.-M. Lange P. I. Hedelund 《Acta Agriculturae Scandinavica, Section A - Animal Sciences》2017,67(3-4):85-95
Flavor of beef has been recognized as an equal quality trait to tenderness and lately high correlations between beef flavor and overall liking of beef have been demonstrated. In this review, we evaluate the effect of breed, sex, age, feeding, growth rate, slaughter method and aging on beef flavor. A common determinator for these factors is their influence on intramuscular fat (IMF) where more IMF increase the overall flavor liking. Feeding can, however, affect the flavor of beef beyond that of the amount of IMF. In several studies, pasture or pasture-based silage lead to a beef flavor characterized as fishy, gamey and grassy in contrast to concentrate-fed beef cattle. A geographical difference in flavor preferences of high-quality beef exists, most clearly illustrated among US consumers who prefer beef from concentrate-fed cattle, whereas European consumers tend to prefer beef from cattle fed a mixed diet on pasture and concentrate. 相似文献
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AIM: To compare the rectal and I/V administration of tramadol in dogs, to assess both its pharmacokinetic properties and absolute bioavailability. METHODS: After rectal administration via suppositories and I/V injection of tramadol (4 mg/kg), the concentration of tramadol and its main metabolites, O-desmethyl-tramadol (M1), N-desmethyl-tramadol (M2) and N,O-didesmethyl-tramadol (M5), were determined in plasma, using high-performance liquid chromatography (HPLC). A balanced cross-over study was used, involving six male Beagle dogs. RESULTS: Plasma concentrations after rectal and I/V administration were fitted on the basis of mono- and bi-compartmental models, respectively. Following rectal administration tramadol was detected from 5 minutes up to 10 hours, in lesser amounts than M5 and M2, while M1 was detected in negligible amounts. Following I/V administration tramadol was detected up to 10 hours, M2 and M5 were detected at similar concentrations, and M1 was present at low concentrations. The area under the curve (AUC) of the three metabolites did not differ significantly after either route of administration of tramadol. The absolute bioavailability of tramadol via rectal administration was 10 (SD 4)%. CONCLUSIONS: After rectal administration of tramadol suppositories, absorption of the active ingredient was rapid, but its metabolism quickly transformed the parent drug to high levels of M2 and M5. CLINICAL RELEVANCE: In the dog, rectal pharmaceutical formulation of tramadol would have a different pharmacokinetic behaviour than in humans. 相似文献
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ZHANG Ji-pei TAN Hua-long CHEN Gang ZENG Qiang ZHANG Fu-ying CHEN Jian-hong 《中国畜牧兽医》2017,44(4):1168-1174
In this study,the biological and genetic characterization of a paramyxovirus type Ⅰ strain (GSFY strain) which was obtained from Muscovy duck were determined. Afterward,GSFY strain was developed as an inactivated oil emulsion vaccine. The protective evaluation of this new vaccine candidate was conducted on the Muscovy duck. The results showed that the mean death time (MDT) of chicken embryo,the intracerebral pathogenicity index (ICPI) of 1-day-old chicken and the intravenous pathogenicity index (IVPI) in 6-week-old chicken were 71 h,1.75 and 2.49, respectively. Homologous comparison of F gene nucleotide sequence showed that the GSFY strain shared 97.1% with Chicken/China/Guangxi 9/2003,which was the highest homology,and they all belonged to type Ⅶ. The results suggested that this newly isolated strain was the type Ⅶ high virulent paramyxovirus. The immunize protective evaluation results suggested that the mean antibody titer of 7 and 21 days after the third immunization were 6log2 and 8log2,respectively. When the immunized duck were attacked with GSFY strain,100% protective rate could be expected when the mean antibody titer was above 5log2. This study provided the basic data for vaccine development of avian type Ⅰ paramyxovirus. 相似文献
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Chronic non-progressive pneumonia (CNP) is a common disease which affects lambs in New Zealand during late summer and autumn. Mycoplasma ovipneumoniae can be recovered from a high proportion of lesions but it is also present in some normal lungs. Bacteria, especially Pasteurella haemolytica, can also be recovered from more than half the lungs of affected animals. Isolates of M. ovipneumoniae are genetically heterogeneous, as demonstrated by examination of their DNA or total cellular proteins, and are serologically heterogeneous as shown by metabolic inhibition tests. The number of strains present in New Zealand is large and several distinguishable strains can be recovered from each affected lung. Mycoplasma ovipneumoniae has pathogenic potential as indicated by its ability to produce hydrogen peroxide, cause ciliostasis and by its possession of a capsule. Chronic non-progressive pneumonia can be transmitted consistently to over 50% of lambs by inoculation of pooled pneumonic lung homogenate and transmission can be suppressed by broad spectrum antibiotics. In contrast, penicillin does not prevent the development of lesions but diminishes their severity. Pooled lung homogenate treated with digitonin, which inactivates mycoplasmas, has failed to transmit CNP. Pure cultures of M. ovipneumoniae produce only mild lesions in some animals, whereas inoculation with pooled lung homogenate (from which no viruses were isolated) containing mixed strains of M. ovipneumoniae and free from bacteria, is more effective in producing lesions. Research work to date suggests that CNP may be initiated by colonisation of the lung by M. ovipneumoniae which causes ciliostasis and elicits an exudate allowing colonisation of the lungs by bacteria especially P. haemolytica and by other strains of M. ovipneumoniae. The immune response to the initial strain of M. ovipneumoniae may inhibit its replication but would be less effective in inhibiting heterologous strains of the organism allowing their sequential replication. Eventually production of a broad immune response to M. ovipneumoniae would lead to its elimination which in turn would facilitate the elimination of other microorganisms and the resolution of lesions. As natural immunity to CNP occurs within the first year, it may be possible to develop an effective and useful vaccine. Such a vaccine may need to include multiple strains of M. ovipneumoniae. 相似文献
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Every AL Selwood L Castano-Rodriguez N Lu W Windsor HM Wee JL Swierczak A Marshall BJ Kaakoush NO Mitchell HM Sutton P 《Veterinary research》2011,42(1):26
ABSTRACT: Since the discovery that Helicobacter pylori causes a range of pathologies in the stomachs of infected humans, it has become apparent that Helicobacters are found in a diverse range of animal species where they are frequently associated with disease. In 2003 and 2004, there were two outbreaks of increased mortality associated with gastric bleeding and weight-loss in a captive colony of the Australian marsupial, the Stripe-faced Dunnart (Sminthopsis macroura). The presence of gastric pathology led to an investigation of potential Helicobacter pathogenesis in these animals. Histological examination revealed the presence of gastritis, and PCR analysis confirmed the presence of Helicobacter infection in the stomachs of these marsupials. Surprisingly, sequencing of 16S rRNA from these bacteria identified the species as H. pylori and PCR confirmed the strain to be positive for the important pathogenesis factor, cagA. We therefore describe, for the first time, an apparent reverse zoonotic infection of Stripe-faced Dunnarts with H. pylori. Already prone to pathological effects of stress (as experienced during breeding season), concomitant H. pylori infection appears to be a possible essential but not sufficient co-factor in prototypic gastric bleeding and weight loss in these marsupials. The Stripe-faced Dunnart could represent a new model for investigating Helicobacter-driven gastric pathology. Infections from their human handlers, specifically of H. pylori, may be a potential risk to captive colonies of marsupials. 相似文献
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van Noort R 《Tijdschrift voor diergeneeskunde》2007,132(12):489-490
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We describe the behaviour of equine influenza (EI) virus infection in a na?ve population as observed by equine veterinary practitioners. The clinical signs displayed by infected horses and the highly contagious nature of the disease are discussed, as well as the treatment and management of infected horses. 相似文献