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1.
A 17-year-old female crossbred cat developed a mass on the left ovary. The mass was solid, firm, 5.5 x 3.5 x 4.5 cm. The mass contained ectodermal components (skin and appendages), mesodermal components (osseous, cartilaginous and adipose structures), and endodermal components (glandular structures lined by columnar epithelium). The tumor was diagnosed as a solid, mature teratoma of the ovary.  相似文献   

2.
An exploratory laparotomy on a mixed‐breed bitch of an estimated age of 5 years revealed that she had undergone ovariectomy in the past, but a cystic structure was present in the area of the right ovary and a whitish mass, approximately 3 cm in diameter, in the area of the left ovary. These structures were removed together with an apparently normal uterus. Histological examination of the cyst showed a thin layer of connective tissue, while the left ovarian mass revealed ovarian tissue and highly differentiated nervous tissue, confirmed through immunohistochemistry. A presumptive diagnosis of mature ovarian teratoma was made. Although teratomas generally contain recognizable elements from more than one of the three germ cell layers, they can also be monophasic, when there is only one germ layer component. Ovarian teratomas are rare in the dog and never before have been reported in an ovarian fragment.  相似文献   

3.
Ultrasonographic examination was carried out in a cow with an ovarian abscess. Real time ultrasound scanning using a 7.5 MHz linear probe per rectum revealed an active left ovary with follicles of up to 11 mm in diameter and an enlarged right ovary measuring 6 x 6 cm, with a mass of 4 x 3 cm. The mass had varied echotexture, a thick hyperechoic boundary and a hypoechoic centre with echoic foci. It was tentatively diagnosed as an ovarian tumour or abscess. After ovariectomy, grossly the right ovary measured 6 x 6 x 5 cm and on cutting cheesy pus oozed out. The abscess was completely localised within the ovary, 4 cm in diameter and encapsulated thickly. On bacteriological examination Staphylococcus spp. was isolated. This is a rare case of ovarian abscess.  相似文献   

4.
A 12-year-old pregnant female giraffe (Giraffa camelopardalis reticulata) died approximately 2 months prior to her anticipated parturition date. At necropsy, a mass measuring approximately 20 x 36 x 20 cm was observed, attached to the umbilical cord, the latter being otherwise normal in appearance. Histologically, the mass contained 3 germinal tissue components with areas of squamous epithelium, respiratory epithelium, primitive neural tissues, glial tissue, peripheral nerve, adipose tissue, cartilage, and smooth muscle. Based on these findings, the tumor was diagnosed as a teratoma originating from the umbilical cord. This is possibly the second reported case of umbilical cord teratoma in animals.  相似文献   

5.
An 8-year-old female African wild dog (Lycaon pictus) from a zoo in Gyeonggi province, Republic of Korea presented with a 3.0 x 2.0 x 2.5 cm in size, smooth-surfaced, solitary pedunculated mass protruding into the uterine lumen. Microscopically, the mass was covered with epithelium, contained endometrial gland tissue, and was dilated in the vascularised stroma. Within the mass, there was extensive diffuse haemorrhage with several blood vessels apparently plugged with fibrin. At the base of the mass, the spaces lined with epithelium near the attachment of the stalk were interpreted to be glandular structures. There were segments of cuboidal epithelium found on the surface of the mass, which was similar to the lining the uterus. A diagnosis of an endometrial polyp was made based on the gross and histology findings. This is the first case report of a spontaneous endometrial polyp in an African wild dog.  相似文献   

6.
Extract

Sir:- In May 1982, an outbreak of severe lameness occurred among mature stags and hinds in a herd of red deer (Cervus elaphus) on a newly-established deer farm near Taupo. No other farm animals were present, the property having been destocked some months before arrival of the deer from several other North Island localities. When the matter was first referred to the local veterinary practitioner, up to 60 animals of the herd of 700 were affected. Males predominated. Most cases had a raw open lesion of the skin in the anterior region of the interdigital cleft with varying degrees of superticial epidermal necrosis as well as some progressive inflammation and ulceration. Destruction of subepithelial tissue was evident in the more advanced cases. In some instances, a deep putrefactive inflammation of the digital connective tissue extended into the phalangeal joints which had become gangrenous. Both front and rear feet were involved, but the horny area of the hoof was intact.  相似文献   

7.
This paper describes the spontaneous ovarian choriocarcinoma observed in a young female Crl:CD1 (ICR) mouse. The mouse was sacrificed at 8 weeks of age after oral administration of a compound for 2 weeks. The left ovary was found to be cystically enlarged with dark red hemorrhaging. The cystic mass contained abundant blood plasma and erythrocytes. At the peripheral regions of the mass, large pleomorphic tumor cells with bizarre shaped nuclei were detected. Tumor cells contained a single large nucleus and abundant eosinophilic to amphophilic cytoplasm. Histopathology of the tumor cells resembled that of trophoblastic giant cells. Therefore, the observed ovarian lesion was diagnosed as a choriocarcinoma. No microscopic lesions were observed in the right ovary or other reproductive organs. Ovarian choriocarcinoma was considered to be of non-gestational origin. This is the first report of ovarian choriocarcinoma in a young ICR mouse.  相似文献   

8.
An oral choristoma in a foal resembling hairy polyp in humans   总被引：1，自引：0，他引：1  
A neonatal foal was presented with a 6.5-cm pedunculated mass arising from the upper deciduous incisors. The distal end was soft and covered by haired skin, whereas the proximal end was firm, covered with mucosal epithelium, and at the point of transection contained a fully developed tooth. Microscopically, the mass was covered by epidermis and mucosal epithelium and the remaining portion of the mass consisted of mature collagen, nonneoplastic fat and smooth muscle, and a single tooth within a bony socket. The mass is consistent with an oral choristoma and has features similar to those described for hairy polyp in humans.  相似文献   

9.
An 11-year-old Quarter Horse mare was presented with ventral edema and pleural effusion, secondary to a disseminated ovarian adenocarcinoma. Bilateral thoracocentesis yielded 30 L of thin, blood-tinged fluid, which was a modified transudate. Cytologic examination of the fluid revealed large atypical cells, suggestive of carcinomatous neoplasia. Similar cells were found in the peritoneal fluid. The mare was euthanatized. Necropsy revealed a 35-cm diameter mass in the cranial mediastinum, ventral to the trachea. The left ovary was 25 cm in diameter and most of the parenchyma was replaced by red or brown friable tissue, containing numerous 1-to 3-mm cysts. Papillary adenocarcinoma of the ovary was diagnosed, based on the appearance and arrangement of tumor cells in the ovary, sublumbar and tracheobronchial lymph nodes, and mediastinal mass. Ovarian neoplasia should be considered in the differential diagnosis of pleural effusion in the horse.  相似文献   

10.
A 6-year-old intact female corn snake (Elaphe guttata guttata) was presented with a 3-week history of anorexia. Coelomic radiographs revealed a 9 x 4 cm soft tissue opacity suggestive of a right ovarian enlargement. The mass (9 x 5 x 4 cm) was surgically removed, and multiple smears from tissue sections were stained with Diff-Quik. Multiple tissue samples from the mass were collected and fixed in formalin. Cytologic specimens were moderately cellular and contained light pink amorphous background material. The cells were primarily spindle-shaped with moderate to marked anisocytosis and anisokaryosis. Cells sometimes were round to polygonal, and rarely were arranged in small clusters. Macrophages occasionally were observed. Histologic specimens consisted of a highly cellular mass composed of pleomorphic, spindle-shaped cells and, occasionally, round to polygonal cells arranged in irregular fascicles. The neoplastic cells were immunoreactive for cytokeratin (AE1/AE3), smooth muscle actin, and skeletal muscle actin, but did not stain for vimentin or desmin. On the basis of the morphologic and immunohistochemical results, a diagnosis of ovarian undifferentiated carcinoma was made. In this report, we describe the challenges of using immunohistochemistry to diagnose this uncommon type of tumor in reptiles.  相似文献   

11.
Multiparous red deer (Cervus elaphus scoticus) hinds (n=17) were either mated to a red deer stag or artificially inseminated with semen from a wapiti bull (C.e. nelsoni) to produce red deer or F1 crossbred (C.e. scoticus × C.e. nelsoni) calves to test the hypotheses that (1) red deer hinds rearing crossbred calves will produce significantly more milk to support calf growth than hinds rearing red deer calves, and (2) hind live weight and body condition may suffer as a result. Hinds and calves were grazed on ryegrass and white clover pastures and supplemented with pasture silage and barley grain when pasture supply was inadequate. Calves were left with their mothers until 9–10 months of age when lactation had terminated naturally. Mean body condition score (BCS) loss was greater in hinds rearing F1 calves than in hinds rearing red calves in the period from late gestation to mid-lactation (September–March, P<0.05). F1 calves grew significantly faster than red deer calves and were heavier at all ages. From February onwards there was a consistent decline in milk intake, and by the latest measurement (22 July) milk production was negligible, and most hinds had ceased lactating. Milk intake by the F1 calves was significantly greater until day 114, after which the measured milk intake was not significantly different. Pasture intake of the F1 calves was significantly greater at day 114 but not at other times (P<0.05). The average hind pasture intake was also not significantly affected by calf genotype when adjusted for post calving hind live weight. The results support the hypothesis that a red deer hind rearing an F1 calf produces significantly more milk than a hind rearing a red deer calf, suggesting that the growth of a red deer calf is limited by its milk demand rather than milk supply by the hind. The study also supported the second hypothesis. Hinds rearing F1 calves exhibited greater losses of body condition score relative to the hinds rearing red deer calves, indicating that the hinds rearing F1 calves were in a greater negative energy balance that hinds rearing red deer calves. This highlights the additional energetic demands on a hind from feeding an F1 calf and in a farmed context the need to ensure that adequate nutrition is provided.  相似文献   

12.
A granulosa-theca cell tumor was found in an ovary that had an ovulation fossa and normal ovarian tissue. The ovary was removed from a mare with a history of ovarian enlargement and behavioral changes. The affected ovary had a multicystic appearance on ultrasonographic examination performed before surgery, and an ovulation fossa was not palpable on examination per rectum. However, during surgery, the affected ovary was found to be within normal size limits, with an enlargement on 1 pole, and to contain an ovulation fossa. Atrophy of the infundibulum of the affected ovary helped to confirm the diagnosis of granulosa-theca cell tumor, and the ovary was removed. The mare's testosterone concentrations were normal. Granulosa-theca cell tumors are usually associated with a spherical ovary, attributable to ablation of the ovulation fossa, with no normal ovarian tissue present.  相似文献   

13.
AIM: To evaluate the efficacy of a new long acting injectable selenium ( Se ) formulation to increase the Se status and prevent Se deficiency in red deer. METHODS: Groups of weaned red deer (four stags and six hinds/group) grazing pastures containing <30 mg Se/kg DM were injected subcutaneously with either 0.5, 1.0 or 2.0 mg Se/kg as a new formulation of BaSeO4 (Deposel Multidose), 1.0mgSe/kg of a current formulation (Deposel), or not treated. Blood Se concentrations and liveweight were measured nine times at intervals over 377 and 270 days, respectively. RESULTS: Both formulations of Se elevated blood Se concentrations from 105 nmol/l pre-injection for at least 377 days with peak levels of 1894, 1395 and 818 nmol/l for high, medium and low doses of Deposel Multidose, respectively, at 73141 days, and 1508 nmol/l at 73-141 days for the medium dose of Deposel, which persisted at similar levels for the duration of the study. Deposel Multidose produced fewer and less severe subcutaneous tissue reactions than Deposel. Pastures contained 10 to 30 mg Se/kg DM. There was no significant difference in growth rate between treated and control deer. There was a significant (p<0. 01) linear relationship (y = 1.25x + 71.6, R2=0.86) between blood (x) and liver (y) Se concentrations in the range of 120 - 2100 nmol/l for blood concentrations, and 200 - 3000 nmol/kg for liver concentrations. CONCLUSION: Injections of BaSeO4 in both formulations studied were effective in increasing the Se status of deer but the new formulation produced fewer and less-severe tissue reactions. Young growing red deer appear less sensitive to Se deficiency as measured by weight gain, than sheep and cattle, suggesting that reference ranges for those species are not appropriate for deer. There was a linear correlation between blood and liver selenium concentrations.  相似文献   

14.
Three cases of bovine, ovarian epidermoid cysts were diagnosed as unilateral benign lesions in three out of 1,971 cows at slaughter. A stratified, cornifying, and squamous epithelium without associated skin adnexal structures or tissues from other embryonic tissue layers lined the cysts. The cysts were small, usually multiple, and contained keratin debris. Macroscopically, they resembled abscesses. These are benign, congenital lesions that are a separate entity from dermoids and teratomas, and they appear to have a higher incidence in cattle with Bos indicus breeding.  相似文献   

15.
Objective Characterization of a benign disease syndrome involving the eyelids of dogs, describing the signalment, clinical appearance, anatomic location, and pathologic features. Animal studied The records and submitted tissue of 10 dogs with mesenchymal hamartomatous lesions of the periocular connective tissues were retrieved from the Comparative Ocular Pathology Laboratory of Wisconsin (COPLOW) database. Procedure The submitted tissue in each case was stained with hematoxilyn & eosin and Masson’s Trichrome stain and examined histopathologically. Clinical information was collected from the submission requests. The clinical history, treatment, and follow‐up are described in more detail for one of the 10 dogs. Results Seven different breeds, including four Golden Retrievers, were represented. The ages of affected dogs ranged from 6 to 11 years. Eight of 10 lesions were located at the temporal canthus, ranging in diameter from 0.6 to 3 cm. Clinically, the masses were subcutaneous, firm, lobular soft‐tissue growths, which were in some cases adherent to the underlying orbital rim, and in others, freely palpable between the skin and conjunctiva of the eyelid. Histologically, all had distinct margins but were not encapsulated and contained normal appearing collagen‐rich connective tissue with some adipose tissue. Five also contained fully differentiated skeletal muscle tissue arranged in poorly formed aggregates or as individual muscle fibers. Conclusion Mesenchymal hamartoma of the eyelid has not been previously described. The mass has a predisposition to occur at the temporal canthus and should be included in the list of differential diagnoses of benign eyelid masses in dogs.  相似文献   

16.

Background

Endometriosis is ectopic development of endometrial glands and stroma in extra-uterine sites and if the lesions occur as a well-defined mass is referred to as endometrioma. In the literature, endometrioma has been reported in only women and there are no reports of endometrioma in animals, including non-human primates.

Case presentation

A rare case of endometrioma is reported in an 11-year-old female German Shepherd with clinical signs of dehydration, anemia and prostration. Necropsy revealed ascites, generalized pallor, and a well-demarcated reddish mass adjacent to the left ovary and uterus and adherent to the retroperitoneum. The mass measured 25.0 × 20.0 cm with intermingled soft and firm areas. Upon incision, the mass was found to be solid with variable sized cystic cavities filled with coagulated blood. Microscopically, the mass was composed of cuboidal or prismatic epithelial cells arranged in tubules or acini. The epithelium of the mass had similar characteristics to the normal endometrium with PAS-positive secretions. The stroma was prominent and formed by loose connective tissue and smooth muscle fibers as confirmed by Masson trichrome. Extensive multifocal areas of hemorrhage were also observed in the stroma of the mass and in the interior of some epithelium-lined, cystic structures. Most of the epithelial cells had strong and diffuse cytokeratin expression, and some had vimentin expression. Epithelial and stromal cells also showed ERβ, AR, VEGF and COX2 expression. The stroma showed areas with strong and diffuse vimentin expression. Factor VIII expression was observed only in the endothelium of blood vessels in the stroma.

Conclusions

The macroscopic, microscopic and immunohistochemical findings are consistent with an endometrioma.  相似文献   

17.
Extract

Sir, — We wish to record for the first time the identification in New Zealand of the nematode parasite Elaphostrongylus cervi Cameron, 1931 (Nematoda: Protostrongylidae) in the red deer (Cervus elaphus) Nematodes of the genus Elaphostrongylus have been reported in connective tissue from a number of sites in members of the deer family in the British Isles and Europe.  相似文献   

18.
对某种鹅场疑似白血病的朗德鹅进行了病理组织学观察。剖检可见病鹅极度消瘦，肝、肾、脾、胆囊和卵巢等组织器官呈不同程度肿瘤样病理变化。其中肝病变尤为明显，稍肿胀，表面有颗粒状弥漫性结节，切面有斑驳状异变；肾苍白，质硬，正常结构消失，形成肿瘤结节；胆囊变硬，胆囊壁增厚。组织切片观察可见肝细胞大量坏死，结缔组织增生，淋巴细胞浸润，肿瘤细胞增生；肾小管上皮脱落，肾间质与肾小球有不同程度的坏死，血管球结构模糊；脾淋巴细胞显著减少，异嗜性粒细胞增多，有多量肿瘤细胞浸润；胰腺、卵巢、胆囊等则有纤维化、淋巴细胞浸润和凝固性坏死等病理变化。  相似文献   

19.
为了探讨塔里木马鹿（Cervus elaphus yarkandensis）干旱环境适应相关基因的结构特征和相关功能,从前期的塔里木马鹿全基因组重测序结果中,筛选获得塔里木马鹿过氧化物氧化还原酶3（thioredoxin-dependent peroxide reductase,PRDX3）基因的序列,对该基因在塔里木马鹿不同组织中的表达情况进行分析,同时对塔里木马鹿PRDX3基因编码区（CDS）序列进行克隆测序,运用相关软件进行同源性比对、构建系统进化树及生物信息学分析。结果显示,塔里木马鹿PRDX3基因在肾脏组织中的基因表达水平极显著高于肺脏和肝脏组织（P<0.01）;塔里木马鹿PRDX3基因CDS序列长660 bp。同源性比对和系统进化树分析结果表明,塔里木马鹿与白尾鹿（GenBank登录号：XM_020875097.1）同源性最高,且遗传距离最近;与褐家鼠（GenBank登录号：NM_022540.1）同源性最低,且遗传距离最远。塔里木马鹿PRDX3蛋白分子质量为24.42 ku,由220个氨基酸组成,不稳定系数为25.36,理论等电点（pI）为5.82,脂溶系数为85.50,总平均亲水性为-0.05,存在O-糖基化位点,具有丰富的磷酸化位点,但是不存在N-糖基化位点、跨膜区及信号肽,最可能位于线粒体中,二级结构和三级结构主要由α-螺旋和无规则卷曲组成,包含PRX_Typ2cys超家族保守结构域,与多种蛋白存在相对较强的相互作用。本研究为后续的塔里木马鹿功能基因的研究奠定基础。  相似文献   

20.
AIMS: To investigate the effects of vaginal Brucella ovis infection on the reproductive performance of red deer (Cervus elaphus) hinds. To determine whether stags may become infected with B. ovis by venereal transmission from mating infected hinds. METHODS: Thirty mixed-age red deer hinds serologically negative for B. ovis antibodies were synchronised for oestrus on 22 March 2000. B. ovis was inoculated into the vagina of each hind at oestrus and again, 18 days later. At oestrus, hinds were randomly allocated to six groups, each joined with a 16 month-old red deer stag seronegative for B. ovis, for 55 days. Hinds were blood sampled and scanned for pregnancy using rectal ultrasonography at monthly intervals. Six pregnant and four non-pregnant hinds were slaughtered pre-calving and three hinds were slaughtered post-calving. Reproductive tracts and foetuses were examined grossly, histologically and microbiologically. Calves were identified and blood sampled within 3 days of birth. Hinds and calves were blood sampled in February and May 2001 and vaginal swabs were collected from hinds for B. ovis culture. Blood was collected from stags, 5 and 19 days after mating and semen was collected for B. ovis culture. The 17 remaining hinds were mated in 2001 to two mixed-age wapiti (Cervus canadensis) stags. Both stags were blood sampled after mating. Sera were tested in a B. ovis complement fixation test (CFT) and enzyme-linked immunosorbent assay (ELISA). RESULTS: All 30 hinds developed B. ovis antibody levels, measurable using either the CFT or ELISA, but these did not remain elevated. There was no evidence of infection, either by gross pathology, histopathology or microbiological culture in the ten hinds or six foetuses slaughtered pre-calving. All remaining 20 hinds produced normal calves, 15 of which survived until weaning. Three hinds experienced dystocia and gave birth to dead calves and two calves died within 4 days of birth. One hind which had dystocia was euthanased. Samples from this hind and from 3/5 dead calves showed no evidence of B. ovis infection. B. ovis was cultured from the vagina of 1/19 hinds 48 weeks after inoculation, at which time B. ovis CFT and ELISA results for this hind were negative. Most calves had B. ovis serum antibodies at 1-3 days of age but levels were negligible when sampled at 10-15 weeks of age. Foetuses and dead calves were all seronegative. Three of the five red deer stags used for mating became infected with B. ovis. The two wapiti stags used to mate the remaining 17 hinds the following year remained seronegative. CONCLUSIONS: B. ovis is unlikely to have significant detrimental effects on the reproductive performance of red deer hinds. Venereal transmission via the vagina of hinds is a possible route of transmission between stags. It is possible that survival of the organism in the vagina of some hinds could create difficulties in disease control programmes. CLINICAL RELEVANCE: B. ovis infection of hinds at the time of mating is unlikely to cause significant reproductive losses. Venereal transmission of B. ovis between stags via the hinds may occur when groups of hinds are joined with more than one stag.  相似文献   

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