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为了观察聚维酮碘消毒剂"可得福"对犬手术伤口的消毒效果,选用2～3月龄、3～5 kg的本地杂交犬10只,随机分为试验组和对照组,试验组选用1.0%～0.5%"可得福",对照组选用2%碘酊和0.1%苯扎溴铵,在相同的手术条件与伤口情形下,对比两组犬分别使用上述药液涂擦或清洗对手术伤口的影响。结果显示,使用"可得福"消毒的有效性和安全性优于2%碘酊和0.1%苯扎溴铵。 相似文献
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1保持哺乳 尽可能在母猪分娩时有人在场,防止新生仔猪受风寒侵袭,用7%的碘酊液消毒仔猪肚脐,仔猪出生后尽可能地剪掉犬齿,但也要避免把牙齿剪得接近牙龈线。尽早地去势仔公猪,时间在3天至2周龄,以减少应激和其他可能的感染,去势前将工具做好消毒。为防止饲养在水泥地面上的仔猪贫血,对出生3~4天的仔猪注射铁剂,如果3星期以后仔猪没有开始喂料,再次注射铁剂。 相似文献
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一白色母仔猪,在去势时未严格消毒,去势3ｄ后不食,呕吐,腹胀,不愿行动。检查发现术部肿胀,伤口未愈合,呈兰紫色。将猪仰卧保定,切开腹部,见腹膜症状,肠管、系膜粘连,腹水呈黄褐色约500ｍＬ,经扩创、剥离肠管及系膜,注入青霉素等药物后缝合腹腔。经治疗和护理恢复健康。此例提醒,母仔猪去势应严格消毒,不要以为猪抵抗力强而忽视消毒工作,否则将会产生不良后果,仔猪发生肠粘连后应及时手术治疗,一般效果良好仔猪去势因消毒不严发生肠粘连@孙广岩$宝清县畜牧局!155600 相似文献
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通过对10日龄的公仔猪进行浓碘酊药物去势与手术去势的比较试验,研究浓碘酊药物去势的效果及其对公仔猪增重的影响。结果表明:药物去势的猪只在术后5～6周阴囊收缩完全,睾丸萎缩丧失其生理功能,去势效果好;手术去势的猪只在术后2周创伤基本痊愈,但有少数猪只因出现感染而延迟痊愈;两种去势方法对公仔猪断奶和70日龄体重的影响均没有显著差异。 相似文献
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公母猪去势后肥育 ,生长迅速 ,节约饲料 ,肉质细嫩。通常采用阉割术摘除公猪睾丸及母猪卵巢 ,但手术较复杂 ,创口易感染 ,更不为广大农户所掌握。新的公母猪去势方法简便 ,术后无感染 ,无出血死亡 ,去势效果与切除睾丸及卵巢相同。(1)公猪化学去势法 “公猪去势液”的配制 :将醋酸液煮沸 5分钟 ,冷却后每 2 0 0ｍｌ加入 0 5ｇ高锰酸钾粉使其充分溶解。用法 :将公猪阴囊注射部位用碘酊消毒 ,直接向每侧睾丸实质注入“去势液”1 5～ 2ｍｌ,每次注射前的注射器和针头都要用 0 5 %高锰酸钾溶液消毒 ,注射药液后局部重新消毒。每头仅需 15～ 2… 相似文献
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德国兽医专家Ernst—Giinther Hellwig博士建议仔猪在3日龄去势。他认为，推迟去势时间仔猪有感染圆环病毒病和猪繁殖与呼吸综合征的危险．而早去势的仔猪可通过初乳得到抗体的保护。日龄小的动物有很高的疼痛阈值(几乎不表现出疼痛的现象)，在去势过程中所受应激少。去势早时手术伤口小， 相似文献
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Lepherd ML Canfield PJ Hunt GB Thomson PC Bosward KL 《Australian veterinary journal》2011,89(3):61-69
Background A two‐part study examined wound healing and contraction occurring after mulesing and two alternative methods of preventing breech flystrike in sheep. Objective To quantify wound healing using a scoring system and to assess the contractility of the wound bed of the breech after mulesing, cetrimide‐intradermal treatment and application of clips. Method The study group of 30 mulesed, 30 cetrimide‐intradermal treated, 30 control and 10 clip‐treated sheep were humanely killed at six time points from 3 to 47 days after each treatment. Wound healing post treatment was assessed using a scoring system, and contractility was assessed by the quantification of myofibroblast expression. Statistical analyses allowed comparisons of temporal wound healing and contraction between treatment groups. Results Mulesing wounds healed faster in the first 11 days, but by 19 days wound healing was similar between the mulesing and cetrimide‐intradermal groups. By 32 days, all three treatment groups had similar wound healing scores. There was greater myofibroblast expression in the mulesing group in the first 11 days after treatment, but by 19 days expression was similar in both the mulesing and cetrimide‐intradermal groups. The clip group had significantly less myofibroblast expression from 32 days after treatment. Conclusion Wound healing is initially most rapid after mulesing, but there are similar wound healing scores in the mulesing and cetrimide‐intradermal treatment groups by 19 days. Both mulesing and the cetrimide‐intradermal treatment induce a similar amount of wound bed contraction, with less contraction observed after application of clips. 相似文献
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Bae JS Jang KH Park SC Jin HK 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2005,67(1):111-114
The effects of topical administration of polysaccharides isolated from fungus, Phellinus gilvus (PG) on the healing of rat dermal wounds were assessed. In 10 Sprague-Dawley (SD) rats, six 6 mm diameter defects were made with a punch biopsy appliance. After 24 hr, test substances were applied to the defects twice a day: 0.025, 0.25, and 2.5% polysaccharides from PG (PG0.025, 0.25, and 2.5 groups), Madecassol ointment (MC group), aqueous gel (AG group) and no treatment (control group). Six days postoperatively, the contraction and reepithelialization of the wound surface were assessed. Wound diameter was significantly reduced in all PG groups (P<0.05). Complete epithelialization and macrophages were noted in the PG0.25 group, as compared to the control group. We conclude that polysaccharides isolated from PG have significant dermal wound healing effects, and this investigation suggests the potential clinical application of PG as a wound healing agent. 相似文献
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旨在研究手术去势后包扎对仔公猪创口愈合、行为、生产性能和血液指标的影响。选择体况良好、体重相近的杜长大仔公猪224头,随机分为3组,分别为假去势组（A组）、去势包扎组（B组）和去势不包扎组（C组）。仔公猪在5日龄进行无麻醉手术去势,21日龄断奶时试验结束。分别在仔公猪去势及包扎后对创口愈合、行为表现、死亡率、生产性能、血清皮质醇（COR）和免疫指标进行评估。结果表明：去势后5 d内,C组仔公猪创口愈合程度的评分显著高于B组（P<0.05）;去势极显著降低仔公猪站立、玩耍和探究等行为（P<0.01）,极显著增加仔公猪独处、惨叫、抱团、异常排尿、站立不稳和恐人等行为（P<0.01）,而创口包扎对仔公猪玩耍和恐人行为有明显改善;在整个试验期内,B和C组仔公猪的断奶重和平均日增重（ADG）与对照组均无显著差异（P>0.05）,去势造成哺乳期仔公猪的死亡率升高,但通过对创口包扎,B组仔公猪在去势后5 d内死亡率（1.35%）明显低于C组（6.41%）;在去势后3 d内,B和C组仔公猪COR浓度均极显著高于对照组（P<0.01）,而在第5天时B组COR浓度显著低于C组（P<0.05）;在去势后3 d内,B和C组仔公猪血清免疫球蛋白A （IgA）和免疫球蛋白G （IgG）浓度均极显著低于对照组（P<0.01）,而去势后第5天时,B组IgA浓度显著高于C组（P<0.05）,白介素-12（IL-12）和干扰素-γ（IFN-γ）浓度在去势前后均无显著差异（P>0.05）。上述结果表明,手术去势造成仔公猪强烈的疼痛应激,而术后包扎可显著降低去势引发的创口红肿出血和感染死亡,加快创口愈合,缓解疼痛造成的行为变化,促进血液指标恢复,从而保障仔公猪的福利水平。 相似文献
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Three sets of paired circular and square full-thickness skin wounds were made on the dorsum of the metacarpus (n = 48) of 8 horses. Each wound was 6.25 cm2 in area. The wounds were treated topically with an ointment, nonadherent dressing, and bandaged with a snug elastic wrap. Wounds were photographed every other day until healing was complete. Wound areas were measured and exponential and linear wound healing models were applied to the wound healing data generated. Wound healing variables measured for each wound were: number of days to healing, maximal size attained, rate of wound contraction (calculated by use of first-order and linear models), final wound size, and percentage of wound that healed by contraction. The exponential model fit the data significantly better than the linear model. The maximal size attained by circular wounds was significantly smaller than the maximal size attained by square wounds. Wound shape did not influence the rate of wound healing. On the basis of our findings, conversion of circular defects to square defects would not speed wound healing. 相似文献
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Principles of wound healing 总被引：2，自引：0，他引：2
A L Bertone 《Veterinary Clinics of North America: Equine Practice》1989,5(3):449-463
Wound healing can be divided into immediate (zero to 1 hour), early (1 to 24 hours), intermediate (1 to 7 days), and late (greater than 7 days) stages. Many physical and physiologic events occur simultaneously and sequentially during these stages to produce the final wound scar. The processes of skin retraction, scab formation, would debridement, wound contraction, epithelial migration and proliferation, fibroplasia, and collagen maturation all must occur for healing to be successful. Many factors affect the size and shape of the resulting scar, including anatomic location and skin tension forces, systemic condition of the patient, blood supply to the wound, nutritional factors, environmental temperature, the presence of systemic drugs, wound infection, motion, wound oxygen gradient, wound moisture, and bandaging. Ideally, each of the factors would occur at a level compatible with optimal healing, but, in many clinical cases, one or more factors compromise normal, rapid healing. When we intervene with therapy, we probably adversely affect another factor in healing, while trying to correct the factor that is out of balance. In these decisions, the effects of our treatment on wound healing should be considered. The trade-off should be weighed and the treatment pursued only as long as necessary to allow healing to progress; then it should be discontinued or changed. With these considerations, it is hoped that we can attain healing at the most rapid physiologic rate. 相似文献
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The aim of this study was to compare the clinical and histopathological effects of tripeptide copper complex (TCC) and two different doses of laser application (helium-neon laser, 1 and 3 J cm(-2)) on wound healing with untreated control wounds. Experimental wounds were created on a total of 24 New Zealand white rabbits and topical TCC or laser was applied for 28 days. The wounds were observed daily, and planimetry was performed on days 7, 14, 21 and 28 to measure the unhealed wound area and percentage of total wound healing. Biopsies were taken weekly to evaluate the inflammatory response and the level of neovascularization. The median time for the first observable granulation tissue was shorter (P < 0.05) in the low and high dose laser groups than in the control group (3 and 2.66 vs. 4.5 days), but was not different between the TCC and control groups (4.16 vs. 4.5 days). Filling of the open wound to skin level with granulation tissue was faster (P < 0.05) in the TCC and high dose laser groups than in the control group (14 and 16 vs. 25 days), but was not different between the low dose laser and control groups (23 vs. 25 days). The average time for healing was shorter (P < 0.05) in the TCC and high dose laser groups (29.8 and 30.2 vs. 34.6 days), but was not different between the low dose laser and control groups (33.8 vs. 34.6 days). Histopathologically, wound healing was characterized by a decrease in the neutrophil counts and an increase in neovascularization. The TCC and high dose laser groups had greater neutrophil and vessel counts than in the control group, suggesting a more beneficial effect for wound healing. 相似文献
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Objective To investigate the effect of a topical anaesthetic formulation on pain alleviation, wound healing and systemic levels of local anaesthetic actives in lambs undergoing castration and tail docking. Design Three placebo-controlled and/or randomised experiments were conducted using three groups of Merino lambs (n = 62, 68 and 19) undergoing routine castration and tail docking. Procedure Surgical castration, with either surgical or hot-iron tail docking, was performed with and without the application of topical anaesthetic (Tri-Solfen®) or placebo. The effects of this procedure were compared with those of rubber ring castration and tail docking, and of the handled but unmarked controls. Wound pain was assessed using calibrated Von-Frey monofilaments over a 4-h period, pain-related behaviour was assessed over 5 h, wound healing was assessed at 14 and 28 days, and the plasma levels of lignocaine and bupivacaine were determined. Results Rapid and up to 4 h primary hyperalgesia developed following surgical castration and tail docking in the untreated and placebo-treated lambs. It was absent in the castration wounds, and significantly reduced in the tail-docking wounds, of the treated lambs. Hot-iron docking was associated with mild and transient secondary hyperalgesia, which was abolished by the topical anaesthesia. There was a significant reduction in pain-related behaviours in treated lambs, which were not significantly different in their behaviour to the sham-operation handled controls. Plasma lignocaine and bupivacaine levels were below the toxic thresholds in all tested lambs. Conclusion Topical anaesthesia alleviates wound pain and significantly reduces pain-related behaviours in lambs undergoing surgical castration plus surgical or hot-iron tail docking, without a negative effect on wound healing or a risk of systemic toxicity. 相似文献
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A perioperative antibiotic for equine castration with second intention healing is controversial because the necessity is unclear and antimicrobial use promotes the selection of resistant bacteria. Information about different regimes for perioperative antimicrobial prophylaxis in equine castration is sparse. Goal of this study was to compare clinical findings, acute-phase proteins, and bacterial cultures in horses undergoing castration, treated with an intravenous single administration of penicillin G sodium (1× Pen group) or a 3-day course of daily intramuscular procaine penicillin (3× Pen group). Forty-eight stallions were castrated under general anesthesia using a closed technique, with second intention healing. Serum amyloid A (SAA) and fibrinogen were measured on days 0, 3, and 8. Body temperature, wound swelling, and drainage were recorded daily over 10 days. Bacterial swabs of the wound were taken on days 0 and 3. Scrotal swelling (P = .032), amount of drainage from the wound (P = .039), and body temperature (P = .013) on day 8 after castration were significantly higher in the 1× Pen group. The concentration of SAA and fibrinogen on day 8 was significantly higher in the 1× Pen group compared with the 3× Pen group (SAA: P = .049; fibrinogen: P = .035). β-Hemolytic Streptococcus spp. were found more frequently cultured in the 1× Pen group than in the 3× Pen group. Clinical and laboratory data indicate lower inflammatory reaction in the early postoperative period after three applications of penicillin compared with a single-administration. Further investigations evaluating the long-term outcome and potential development of antimicrobial resistant bacteria are needed. 相似文献
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Alexandra K. Tracey Cody J. Alcott Jennifer A. Schleining Sina Safayi Peter C. Zaback Jesse M. Hostetter Eric L. Reinertson 《The Canadian veterinary journal. La revue veterinaire canadienne》2014,55(12):1146-1152
Topical oxygen therapy (TOT) has been used in human medicine to promote healing in chronic wounds. To test the efficacy and safety of TOT in horses, an experimental wound model was created by making 1 standardized dermal wound on each limb of 4 healthy horses (n = 16). Each wound was fitted with an oxygen delivery cannula and covered with a bandage. One limb of each front and hind pair was randomly assigned to the treatment group (fitted with an oxygen concentrator device), with the contralateral limb assigned to the control group (no device). Wound area, epithelial area, and contraction were measured every 3 to 4 d. Biopsy samples and culture swabs were taken on days 16 and 32 to evaluate angiogenesis, fibroplasia, epithelial hyperplasia, inflammation and bacterial growth. Mean healing time in treated wounds (45 d, range: 38 to 52 d) was not significantly different from that in the paired control wounds (50 d, range: 38 to 62 d). Topical oxygen therapy had little effect on dermal wound healing in this experimental wound model in healthy horses. 相似文献
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V S Pandey 《Tropical animal health and production》1979,11(3):175-178
Clinical trials were carried out on 3 groups of 30 Friesian cattle naturally infected with Trichophyton verrucosum. One group was treated with 3.75% thiabendazole in glycerine, another with 5% tincture of iodine and the last served as the control group without any treatment. Both the preparations were applied locally on the ringworm lesions at 3 day intervals with a total of 4 applications. The percentage of animals cured was 86.7 by thiabendazole and 46.7 by tincture of iodine. No recrudescence was observed during the subsequent 4 months period. 相似文献