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2003年4月初,新郑某种羊场从山东梁山地区引进小尾寒羊231只,由于长途运输及环境条件的改变,羊抵抗力降低,加之羊场初建,各种消毒设施不建全,饲养人员无经验,二天后羊发病,一周内死亡23只,造成较大的经济损失。但由于诊疗及时、方案合理、防治措施得力,病情很快得到控制。现将诊疗及综合防治情况报告如下:1发病情况4月2日,231只小尾寒羊运至场中,4日发现2只体温升高,精神食欲不佳,进行对症治疗后,效果不显著,数小时内死亡。第二天十多只羊发病,随即带病羊到兽医防治站进行实验室检验,结果为魏氏杆菌、巴氏杆菌和附红细胞体混合感染,用药后至… 相似文献
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羊魏氏梭菌病是由魏氏梭菌引起的,主要发生于羊的毒血症,包括羊猝狙、羊肠毒血症、羔羊痢疾等.疗效不明显,对养羊业造成很大的危害.2008年3月5日,我站对223团送检的1只病羊进行解剖,病变症状明显,现将诊疗过程报告如下. 相似文献
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<正> 羊梭菌性疾病在这里指的是羊快疫、羊肠毒血症、羔羊痢疾和羊猝疽四种病。2003年4月,承德市某小尾寒羊养殖户突然死亡三只成年羊(其中有一只种公羊),前后不到4小时,羊死后从口鼻流出带血的泡沫,另有三只羊食欲废绝,精神沉郁,反刍停止,呻吟,磨牙,站立不稳,头颈向上抬,呼吸困难,体温40.5℃,心跳加快。解剖三只病死羊,营养良好,腹腔膨大,打开腹腔有大量恶臭气体,真胃黏膜有出血点、出血斑,黏膜下组织水肿,胸腔、腹腔、心包积有大量液体,心内膜、心外膜和心室有出血点,胆囊肿大、充满胆汁,肠道和肺尖叶瘀血。根据病羊临床症状和病死羊剖检病理变化,初步诊断为羊快疫,随后采取肝,用肝脏组织乳剂接种小白鼠,接种后16小时小白鼠死亡,取小白鼠肝脏触片,用美蓝染色,进行镜检,见到无关节、长丝状、两端钝圆大杆菌,确诊为腐败梭菌。为防止和杜绝羊快疫、羊肠毒血症、羔羊痢疾、羊猝疽的疾病发生,建议养殖户要采取以下几个方面的综合防治措 相似文献
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因羊肉肉质细腻,营养价值高,是现代餐桌不可缺少的佳肴之一,而且羊的副产品也有极其重要的使用价值,因此,养羊业逐渐发展起来。但是,最近几年,羊梭菌病对羊只危害极大,给养殖户带来了一定的经济损失。羊梭菌病病因繁多,给防治工作带来了一定的难度,为有效防止该病发生,养殖户应注意引发羊梭菌病的原因并进行综合防治。1发病原因1.1地理环境因素羊只发生梭菌病与地理环境有一定的关系,经常定居在潮湿、低洼以及沼泽地带的羊只易发生本病。而在地势高燥的地区则不易发生本病。1.2气侯因素气候因素对羊梭菌病的发生影响密切。我国北方冬季气候… 相似文献
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在羊养殖过程中需要对比较常见的疾病做预防,这样,羊养殖效益才会有效的提升。将江苏地区的羊养殖来看,在养殖实践中比较常见的是羊梭菌性疾病,这种由梭状芽孢杆菌属细菌引发的传染性疾病不仅发生快,死亡也很快,所以其对养殖威胁特别大,所以在实践中做好羊梭菌性疾病的防治非常的必要。文章就羊梭菌性疾病的防治方法做具体分析,旨在为目前的羊养殖实践工作提供帮助与指导。 相似文献
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作为一种较为常见且具有较高传染性的羊病,羊梭菌性疾病的致死率相对较高,如果无法对其进行有效防治,势必会影响羊群的健康生长发育,同时也会为养殖户造成一定收益风险。因此本文将通过参考相关资料,从羊梭菌性疾病的分类入手,在阐明其主要临床症状下,对羊梭菌性疾病提出几点有效防治策略以供参考。 相似文献
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羊梭菌性疾病是由梭状芽孢杆菌属中的细菌所致的一类疾病,包括羊快疫、羊肠毒血症、羊猝疽、羊黑疫和羔羊痢疾。本文详细叙述了羊梭菌性疾病类型及流行特点,并提出了一些防治对策,以期为今后该病的临床治疗提供相关参考。 相似文献
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介绍了高原型藏羊梭菌病临床症状及防治措施,希望牧户能够从疫苗、日常管理及诊断和治疗等方面着手以降低藏羊梭菌病造成的死亡率和发病率,有效地控制藏羊梭菌病。 相似文献
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本文阐述了永靖县羊梭菌病的调查情况,通过查阅资料、临床检查、实验室诊断等方法调查,查清了羊梭菌病在永靖县的发病率、死亡率、发病季节、病羊的品种及年龄、流行区域性等流行特点,制定出了科学的防治措施。 相似文献
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宁夏盐池县某养殖场饲养的羊发生了突然倒地死亡,或晚上没有任何症状而次日晨死于羊圈为特征的疾病,经诊断为羊A型魏氏梭菌病。现将诊断和防治情况报道如下。1流行情况该养殖场共饲养羊1328只,发病324只,全部死亡。发病羊都是青壮年羊,营养比较好,发病地区羊没有进行羊梭菌病疫苗免疫注射。本病为散发,1个羊群发病后,附近其他羊群不一定同时发病。在1个羊群中出现后,一般要延续10～20d,表现为陆续发病、死亡。2临床症状在5个发病羊群中,初期都有3～5只羊急性死亡,或在放牧途中或正在吃草即突然倒地挣扎几下就死去;或向前猛冲,腾空而起然后… 相似文献
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The flagellin genes (fliC) of Clostridium chauvoei, Clostridium haemolyticum, Clostridium novyi types A and B, and Clostridium septicum were analysed by PCR amplification and DNA sequencing. The five Clostridium species have at least two copies of the flagellin gene (fliC) arranged in tandem on the chromosome. The deduced N- and C-terminal aminoacid sequences of the flagellin proteins (FliCs) of these clostridia are well conserved but their central region aminoacid sequences are not. Phylogenic analysis based on the N-terminal aminoacid sequence of the FliC protein revealed that these clostridia, which belong to Clostridium 16S rDNA phylogenic cluster I (), are more closely related to Bacillus subtilis than to Clostridium difficile, which belongs to the cluster XI. Moreover, a multiplex polymerase reaction (PCR) system based on the fliC sequence was developed to rapidly identify C. chauvoei, C. haemolyticum, C. novyi types A and B, and C. septicum. PCR of each Clostridium amplified a species-specific band. The multiplex PCR system may be useful for rapid identification of pathogenic clostridia. 相似文献
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The minimal inhibitory concentrations (MICs) of 10 antimicrobial agents against a total of 33 isolates of Clostridium perfringens, Clostridium septicum and Clostridium sordellii from cattle affected with malignant edema in Japan was determined. The low MIC activities of benzylpenicillin confirm the place of benzylpenicillin as the antibiotics of choice for treatment of malignant edema. Five (22%) of 23 C. septicum strains, five (71%) of seven C. perfringens strains and all strains of C. sordellii showed resistance to oxytetracycline. These oxytetracycline-resistant strains carried tetracycline-resistance genes [tetA(P), tetA408(P), tetB(P) and tetM]. The sequences of the tetracycline-resistance genes of some C. septicum strains were completely or nearly completely identical to those of strains belonging to other clostridiual species. This is the first report of resistance of C. septicum to tetracycline. 相似文献
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Uzal FA Diab SS Blanchard P Moore J Anthenill L Shahriar F Garcia JP Songer JG 《Veterinary microbiology》2012,156(3-4):395-402
Clostridium perfringens type C is one of the most important agents of enteric disease in newborn foals. Clostridium difficile is now recognized as an important cause of enterocolitis in horses of all ages. While infections by C. perfringens type C or C. difficile are frequently seen, we are not aware of any report describing combined infection by these two microorganisms in foals. We present here five cases of foal enterocolitis associated with C. difficile and C. perfringens type C infection. Five foals between one and seven days of age were submitted for necropsy examination to the California Animal Health and Food Safety Laboratory. The five animals had a clinical history of acute hemorrhagic diarrhea followed by death and none had received antimicrobials or been hospitalized. Postmortem examination revealed hemorrhagic and necrotizing entero-typhlo-colitis. Histologically, the mucosa of the small intestine and colon presented diffuse necrosis and hemorrhage and it was often covered by a pseudomembrane. Thrombosis was observed in submucosal and/or mucosal vessels. Immunohistochemistry of intestinal sections of all foals showed that many large bacilli in the sections were C. perfringens. C. perfringens beta toxin was detected by ELISA in intestinal content of all animals and C. difficile toxin A/B was detected in intestinal content of three animals. C. perfringens (identified as type C by PCR) was isolated from the intestinal content of three foals. C. difficile (typed as A(+)/B(+) by PCR) was isolated from the intestinal content in 3 out of the 5 cases. This report suggests a possible synergism of C. perfringens type C and C. difficile in foal enterocolitis. Because none of the foals had received antibiotic therapy, the predisposing factor, if any, for the C. difficile infection remains undetermined; it is possible that the C. perfringens infection acted as a predisposing factor for C. difficile and/or vice versa. This report also stresses the need to perform a complete diagnostic workup in all cases of foal digestive disease. 相似文献
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本研究探索了丁酸梭菌分离株的益生特性，旨在为其在仔猪日粮中的应用提供理论依据。利用常规方法分离丁酸梭菌并进行纯培养，经生化检测和16S rRNA基因测序，对分离菌株进行鉴定；采用活菌计数法和牛津杯法研究分离株培养上清对3种致病菌的抑制作用、分离株黏附猪小肠上皮细胞（IPEC-J2）的特性及其对致病菌黏附细胞的抑制作用；采用细胞计数法研究分离株对IPEC-J2生长的影响；采用ELISA检测分离株处理细胞后培养上清液中细胞因子水平。结果表明，本研究成功分离到一株丁酸梭菌。与对照组相比，丁酸梭菌培养上清对3种致病菌生长抑制效果均显著（P<0.05）；丁酸梭菌可黏附于IPEC-J2，并且黏附效果最佳的感染复数（MOI）为50，最适处理时长为3 h；丁酸梭菌对3种致病菌黏附IPEC-J2均具有显著抑制作用（P<0.05）；丁酸梭菌MOI为1、10和50时细胞生长正常、形态完好，MOI为100时IPEC-J2生长受到显著抑制，同时出现部分细胞死亡；MOI为1时细胞因子水平无差异，MOI为10、50和100时细胞因子水平均显著增高（P<0.05）。综上所述，本研究分离的一株丁酸梭菌具有较好的益生特性，为其在生产中的应用提供了理论依据。 相似文献
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Clostridium difficile is well known as the most common cause of nosocomial infections in human patients. In recent years a change in epidemiology towards an increase in incidence and severity of disease, not only inside the hospital, but also in the community, is reported. C. difficile is increasingly recognized in veterinary medicine as well and is now considered the most important cause of neonatal diarrhea in swine in North America. Research on the presence of C. difficile in production and companion animals revealed a huge overlap with strains implicated in human C. difficile infection (CDI). This has lead to the concern that interspecies transmission of this bacterium occurs. In this review C. difficile infections in humans and animals are compared. The pathogenesis, clinical signs, diagnosis and prevalence of CDI are described and similarities and differences of CDI between humans and animals are discussed. 相似文献
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