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1.
为了研究肾脏部分切除与肾脏切除对小型猪术后恢复情况的影响,试验以6头广西巴马小型猪作为试验动物,将其平均分为腹腔镜肾脏部分切除术组(LPN)与腹腔镜肾脏切除术组(LRN),于术前、术后即刻、术后第1天、第2天、第3天、第5天、第7天分别监测心率、血压、体温、呼吸,并采血检测血常规与血肌酐和血尿素氮,比较两组术后恢复情况。结果表明:LPN组与LRN组比较,术后心率、呼吸、白细胞数、血肌酐有一定程度升高,但差异不显著;LPN组术后即刻体温显著低于LRN组(P0.05),术后第7天血尿素氮高于LRN组,差异极显著(P0.01)。说明腹腔镜肾脏部分切除术与腹腔镜肾脏切除术相比对术后恢复的影响较大,应谨慎选择。  相似文献   

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本试验选用4只成年本地杂交犬,进行左肾肾实质切开术。分别于术前、术后第3d、10d、20d、30d测定血清进行尿素氮(BUN)、肌酐(CRE)和尿酸(UA)3项肾功能指标。术后常规护理,当各项指标完全恢复到正常范围1个月后进行左肾摘除,观察肾形态变化,2只做右肾切开术,并于术前和术后1个月测定肾功能指标。结果表明,犬在肾切开术后20d后三项生化指标可基本恢复至正常状态。术后第5d试验犬的精神状态和食欲均恢复到术前水平。肾脏切开术治疗犬肾结石的方法在临床操作中是可行的。  相似文献   

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为了对比腹腔镜和开腹肾脏切除手术对犬机体氧化应激的影响,为腹腔镜手术在兽医领域的发展提供理论依据,试验在犬腹腔镜和开腹组肾脏切除术前及术后即刻、4小时、1天、2天采取静脉血,检测丙二醛(MDA)、超氧化物歧化酶(SOD)和谷胱甘肽过氧化物酶(GSH-Px)。结果表明:腹腔镜和开腹肾脏切除术都使MDA含量升高,SOD和GSH-Px水平降低。但是腹腔镜组影响较为迅速,术后4小时与术前相比差异极显著(P<0.01),术后1天就恢复到术前水平;开腹组术后1天才与术前相比差异显著(P<0.05),术后2天也未能恢复到术前水平。说明腹腔镜和开腹肾脏切除术都能造成犬机体氧化应激损伤,但与开腹肾脏切除术相比,腹腔镜手术对动物机体氧化应激损伤轻。  相似文献   

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为了探索犬肾结石的手术治疗方法,本试验选3~5个月之间,体重6~10 kg的本地杂交犬2只,采用镰刀状肾实质切开法行左侧肾脏切开,分别于术前、术后第3、7、14、21、28天采集血清进行尿素氮(BUN)、肌酐(CRE)两项肾功能指标测定,并于术后观察其整体状态、排尿表现及肾脏的形态变化。结果表明,手术导致试验犬肾功能指标在术后1~2周内明显降低,于3~4周恢复正常;术肾与健康右肾相比,呈现不同程度的萎缩。  相似文献   

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探讨腹腔镜胆囊切除术(LC)和开腹胆囊切除术(OC)对试验犬的手术时间、切口长度及免疫应激指标的影响,比较两种手术方法的优缺点.试验结果表明,开腹手术组术后各项指标变化都明显高于腹腔镜手术组,所以腹腔镜手术要优于开腹手术.  相似文献   

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山羊腹腔镜卵巢切除手术   总被引:1,自引:0,他引:1  
应用腹腔镜对10只成年未孕母山羊进行卵巢切除术试验,并于术后10d做第2次腹腔镜手术,以探查腹腔内施术部位愈合情况。结果表明,术后10只山羊的卵巢系膜和输卵管断端愈合良好,套扎线已经被组织包埋,手术部位均未发生粘连。  相似文献   

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《中国兽医学报》2014,(12):2005-2008
对14头健康小型猪分别进行开腹(open cystostomy,OC)、腹腔镜膀胱造口手术(laparoscopic cystostomy,LC),通过检测小型猪术后不同时间点血清皮质醇(cortisol,COR)、白介素-6(Interleukin-6,IL-6)和C反应蛋白(C-reactive protein,CRP)的变化,比较OC手术与LC手术对机体应激反应的影响。结果表明,LC、OC2组分别在不同时间点所检测到的的COR、IL-6和CRP与试验前相比,都有极显著性差异(P<0.01)。在术后即刻和4h后OC组对应激指标的影响要明显高于LC组,并且术后3dLC组都恢复到试验前水平,而OC组术后5d才恢复。说明LC和OC都可导致血清中COR、IL-6、CRP水平的升高,但OC较LC对COR、IL-6和CRP的影响更为显著,即腹腔镜膀胱造口手术比开腹膀胱造口手术对机体应激反应的影响更小。  相似文献   

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本研究旨在探讨2种安装多位点血管瘘手术方法对山羊机体免疫应激的影响。选取8只体重相近、年龄约1岁的健康麻城黑山羊公羊,按体重相近的原则分成2组,分别采用腹腔镜法与传统开腹法手术安装山羊肠系膜静脉、门静脉及肝静脉血管瘘管。测定术前、术后第1、3、5天试验羊血清免疫应激指标。结果表明:术后第1天,腹腔镜组白细胞总数显著低于开腹组(P0.05),C反应蛋白(CRP)水平极显著低于开腹组(P0.01),Ig G水平显著高于开腹组(P0.05);术后第3天,腹腔镜组IL-6、CRP水平显著低于开腹组(P0.05);术后腹腔镜组和开腹的TNF-α、Ig A和Ig M水平差异不显著(P0.05)。本试验结果表明,腹腔镜手术对山羊机体应激更小,机体免疫功能恢复更快。  相似文献   

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本研究采用不同肾切除手术方法,研究大鼠肾脏损伤及疾病病程变化规律。研究表明,肾脏的缺失并未影响大鼠机体体重的改变,术后2周开始不同肾切除大鼠肾脏病变规律发生差异性改变。1/2肾切除大鼠肾脏缺失后存在明显代偿性作用,血肌酐、血尿氮缓慢上升,尿肌酐、肌酐清除率下降迟缓,肾小管、肾小球组织损伤均为轻度损伤;5/6肾切除大鼠肾缺失后肾脏各项指标急剧恶化,血肌酐、血尿氮快速上升,显著高于1/2肾切除大鼠(P0.01),尿肌酐、肌酐清除率显著快于1/2肾切除大鼠下降程度(P0.01),肾小管上皮受损严重,肾小球重度硬化,间质存在炎性细胞浸润。该研究为建立肾脏缺失模型提供了依据。  相似文献   

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试验选用14头健康小型猪,随机分成两组,分别进行腹腔镜膀胱造口术(LC组)和开腹膀胱造口术(OC组)。两组手术全程用重症监护仪和呼吸监护仪进行监护,在试验前、麻醉后、术中10、30、60 min及术后即刻记录RR、HR、BP、SpO_2、PetCO_2和T,以分析对比两种手术方法对机体生理功能的影响。两组手术均成功完成,LC组术中HR、BP、SpO_2高于OC组,但差异不显著。LC组术中RR和PetCO_2显著高于OC组(P0.01),术后即刻在数值上LC组高于OC组,但差异不显著(P0.05)。结果表明,与开腹手术相比,腹腔镜手术在术中对机体主要的临床体征未产生较大不良影响,从而证明腹腔镜下小型猪膀胱造口术是安全可行的。  相似文献   

11.
OBJECTIVE: To describe a hand-assisted, laparoscopic technique to remove the left kidney in standing horses. STUDY DESIGN: Prospective evaluation. ANIMALS: Eight horses. METHODS: Food was withheld for a minimum of 12 hours. Horses were sedated with detomidine hydrochloride (0.01-0.02 mg/kg, intravenously) and restrained in standing stocks. The left paralumbar fossa was prepared for surgery, and the surgical site was infiltrated with 2% mepivacaine. Hand-assisted, laparoscopic removal of the left kidney was performed through an incision in the center of the paralumbar fossa; the surgeon's hand was used to isolate the left kidney and associated vasculature. The renal artery and vein were isolated and individually ligated. After vessel transection distal to the ligatures, the left kidney was exteriorized, the ureter ligated and transected, and the incision closed. RESULTS: Laparoscopic removal of the left kidney was successfully performed in all horses. Retroperitoneal infiltration of local anesthesia provided adequate anesthesia. Intraoperative hemorrhage occurred in 3 horses. Surgical duration (initial skin incision to transection of the left kidney) ranged from 20 to 90 minutes. In 2 horses, no signs of pain were noted for 48 hours postoperatively. CONCLUSION: Hand-assisted laparoscopic surgery can be used for removal of the left kidney in horses. Clinical Relevance-Hand-assisted laparoscopic nephrectomy can be safely performed in standing horses; however, care should be taken to identify accessory branches of the renal artery to limit potential complications with hemorrhage.  相似文献   

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An 18‐year‐old Quarter Horse gelding was examined for haematuria of 6 weeks' duration. Rectal examination identified an enlarged left kidney and ultrasonographic examination of the kidney identified grossly abnormal renal architecture. Hand‐assisted laparoscopic nephrectomy was performed following laparoscopic exploration of the abdomen for metastatic disease. A laparoscopic stapling device was successfully used to transect and ligate the renal vasculature and ureter. Histopathological examination of the kidney identified renal cell carcinoma. A 7 month survival was documented following surgery. Unilateral nephrectomy should be considered a therapeutic or palliative procedure for horses with renal cell carcinoma.  相似文献   

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Objective: To describe clinical and imaging findings, treatment, and long‐term outcome of cattle undergoing unilateral nephrectomy. Study Design: Case series. Animals: Cattle (n=10). Methods: Medical records (January 1991–August 2008) of cattle that had unilateral nephrectomy were reviewed. Follow‐up data were obtained by owner telephone interview. Results: Nephrectomy was performed without surgical complications. Transient increases in blood urea nitrogen and creatinine concentrations occurred after surgery and then returned to, or below, presurgical values in 9 cattle. Nine cows were discharged and 7 rejoined their respective herd as productive animals without long‐term complications. Conclusions: Ultrasonography was the most useful imaging tool for presurgical diagnosis. Based on our follow‐up data, unilateral nephrectomy resulted in few serious short‐term or long‐term complications, and cattle undergoing this procedure are capable of satisfactory growth, reproduction, and milk production after surgery.  相似文献   

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Objective— To describe a technique for, and outcome after, left‐ or right‐sided laparoscopic‐assisted nephrectomy in standing horses with unilateral renal disease. Study Design— Clinical report. Animals— Horses (n=3) with unilateral renal disease. Methods— Horses were sedated with detomidine (0.01 mg/kg intravenously [IV]) and levomethadone (0.05 mg/kg IV). Paravertebral anesthesia and infiltration‐anesthesia with 2% lidocaine were used to create a surgical field incorporating the 17th intercostal space and paralumbar fossa. Two separate, ipsilateral portals and a mini‐laparotomy were used. The perirenal peritoneum was horizontally incised (10–15 cm) using endoscissors and the incision digitally enlarged for manual dissection of the perirenal fat and kidney mobilization. The renal vessels and ureter were individually dissected, ligated, and transected under laparoscopic observation and the kidney removed. The perirenal and laparotomy peritoneal defects were not closed; and the laparotomy was closed in a multilayered fashion. The transverse abdominal muscle was apposed in a continuous pattern using 1 polyglactin 910, the subcutaneous tissue (simple continuous pattern) and skin (simple interrupted pattern) with 2–0 polyglactin 910. Results— Left (2) and right (1) sided laparoscopic‐assisted nephrectomy (1 nephrolithiasis, 2 hydronephrosis) was performed successfully. Sedation and local anesthesia was adequate for intraoperative immobilization and analgesia. No intraoperative complications occurred. Incisional seroma formation and fever occurred on days 3 and 4 in 1 horse and resolved with medical management. Conclusion— Laparoscopic‐assisted nephrectomy can be used for removal of the left or right kidney in standing horses with unilateral kidney disease. Clinical Relevance— To avoid risks associated with general anesthesia and to reduce surgical trauma, laparoscopic‐assisted nephrectomy can be performed in the standing sedated horse using a 2 portal technique and a mini‐laparotomy.  相似文献   

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A young rabbit was diagnosed with unilateral hydronephrosis. The affected kidney was surgically removed. Nearly 3 years after the nephrectomy, the rabbit is doing well. The diagnosis, surgery, and pathophysiology of unilateral renal obstruction are discussed in this article.  相似文献   

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