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1 功能基因组学概况 基因组这一概念于1924年提出,用于描述一种生物的全部基因和染色体组成.基因组学(genomics)由美国科学家Thomas Roderick于1986年提出,是指对基因组进行作图、序列分析、基因定位及功能分析的科学,并将其作为一个新创刊的杂志名. 相似文献
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功能基因组学研究进展 总被引：3，自引：0，他引：3
2 1世纪是生物时代和信息时代 ,基因组学的研究已从结构基因组学转向功能基因组学 ,对于基因功能的研究也由单一基因转向大规模、批量分析。文章对功能基因组学及相关学科的概念作了概述 ,介绍了功能基因组学的研究内容与研究方法 ,主要包括应用差异显示反转录 PCR、基因表达序列分析 (SAGE)、微点阵、蛋白质组学和生物信息学等研究基因组表达概况、基因组多样性和模式生物学等。 相似文献
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功能基因组学研究进展 总被引：1，自引：0，他引：1
基因组研究计划包括以全基因组测序为目标的结构基因组学和以基因功能鉴定为目标的功能基因组学2方面的内容.作者对功能基因组的主要研究方法:微阵列或DNA芯片、表达序列标签法、基因表达系列分析法、蛋白质组学分析法以及反向遗传学技术等进行了简要介绍,同时综述了上述各种技术的优缺点以及部分生物功能基因组的研究进展. 相似文献
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1蛋白质对于解决肥胖问题起着很重要的作用
蛋白质能够满足饱感并且转化成肌肉组织，蛋营养中心主任Don McNamara，最近在匈牙利首都布达佩斯举行的国际蛋品协会大会上说：“鸡蛋蛋白质易产生饱感，无脂肪组织并促进肌肉组织生长。这些都给鸡蛋带来巨大的推广潜力。”他补充道：“现在西方国家最关注的健康问题是肥胖。蛋白质对于解决肥胖问题起着很重要的作用，当你试图减肥时，蛋白质能够满足你的饱感并且转化成肌肉组织。” 相似文献
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B.A. Breuhaus 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2009,23(1):168-173
Background: This study was performed to determine whether anhidrotic horses have altered thyroid function compared with horses that sweat normally.
Hypothesis: Anhidrotic horses have normal thyroid function.
Animals: Ten client-owned horses with clinical signs of anhidrosis were paired with 10 horses living in the same environment that had normal sweat production.
Methods: Horses were diagnosed as having normal sweat production or being anhidrotic based on responses to intradermal injections of terbutaline and physiologic responses to lunging exercise. Control horses were selected from the same environment and matched as closely as possible to anhidrotic horses in terms of age, sex, breed, and athletic condition. Thyrotropin-releasing hormone (TRH) stimulation tests were performed in both horses at the same time, once in the summer or fall, and once again in winter.
Results: Anhidrotic horses produced less sweat in response to intradermal injections of terbutaline and exercise than did control horses. They also had greater increases in body temperature and respiratory rate in response to exercise. Resting concentrations of thyroid hormones and thyroid-stimulating hormone (TSH) were not different between anhidrotic and control horses. Thyroid hormone responses to TRH also were not different between the 2 groups of horses. However, anhidrotic horses had a significantly different TSH response to TRH compared with control horses, particularly in the winter.
Conclusions and Clinical Importance: The biologic relevance of the altered TSH response to TRH in anhidrotic horses is uncertain, considering that TSH concentrations remained within previously reported normal ranges and thyroid hormone responses were not different between anhidrotic and control horses. 相似文献
Hypothesis: Anhidrotic horses have normal thyroid function.
Animals: Ten client-owned horses with clinical signs of anhidrosis were paired with 10 horses living in the same environment that had normal sweat production.
Methods: Horses were diagnosed as having normal sweat production or being anhidrotic based on responses to intradermal injections of terbutaline and physiologic responses to lunging exercise. Control horses were selected from the same environment and matched as closely as possible to anhidrotic horses in terms of age, sex, breed, and athletic condition. Thyrotropin-releasing hormone (TRH) stimulation tests were performed in both horses at the same time, once in the summer or fall, and once again in winter.
Results: Anhidrotic horses produced less sweat in response to intradermal injections of terbutaline and exercise than did control horses. They also had greater increases in body temperature and respiratory rate in response to exercise. Resting concentrations of thyroid hormones and thyroid-stimulating hormone (TSH) were not different between anhidrotic and control horses. Thyroid hormone responses to TRH also were not different between the 2 groups of horses. However, anhidrotic horses had a significantly different TSH response to TRH compared with control horses, particularly in the winter.
Conclusions and Clinical Importance: The biologic relevance of the altered TSH response to TRH in anhidrotic horses is uncertain, considering that TSH concentrations remained within previously reported normal ranges and thyroid hormone responses were not different between anhidrotic and control horses. 相似文献
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The authors compared the thyroid function of cows with primary ketosis and clinically healthy cows in the same stage of lactation by a method based on the in vitro erythrocyte uptake of L-3,5,3′- triiodothyronine labelled with I131. This method (EU) proved to be affected by, among other factors, the content of total protein in the blood plasma, which was lower in ketotic than in normal cows. This caused difficulties in interpretation of the measured EU, but the authors consider that the experiments indicated an elevated thyroid activity in ketosis. The importance of continued research into the probable relation between thyroid function and ketosis is stressed. 相似文献
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酶制剂的功能与动物营养学 总被引：2，自引：0，他引：2
<正>饲料酶制剂研究发展很快,但是目前饲料酶制剂开发仍然存在许多问题,酶制剂在畜禽日粮中的应用还有不少的争议,而且这些问题和争议将会很长时间存在,目前,不少的饲料酶制剂产品达不到作为饲料添加剂的要求,产品设计的盲目性还比较普遍。但不可否认,酶制剂是最有发展前景的饲料添加剂之一。作为一类具有生物学活性的生物技术产品,天然、绿色、安全、高效是其本身的特性,决定了其使用具有广 相似文献
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194 9年 ,美国首次发现抗生素对畜禽有促生长作用 ,从此 ,许多国家将抗生素广泛应用于畜牧业 ,取得了明显的经济效益。我国早在 2 0世纪 50年代末 ,在抗生素生产起步阶段就将土霉素滤渣用于畜禽饲料添加剂 ,在饲养过程中起到了良好的效果。我国比较全面地使用抗生素作为饲料添加剂 ,仅仅有十余年的历史。随着世界各国对食品安全工作的高度重视 ,滥用抗生素作饲料添加剂带来的抗药性、药物残留等问题日见突出 ,仅美国在 1 992年就有 1 330 0名患者死于抗生素抗药性细菌感染。对此 ,美国、欧盟都已相继颁布一系列法律在饲料中禁止或限制使用抗… 相似文献
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D. Hoffman J. Amorim A. DeClue 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2018,32(1):208-216