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1.
目的试验阿维菌素复方制剂2号中左旋咪唑与阿维菌素混合有无配伍禁忌及驱除绵羊体内外寄生虫效果。方法通过虫卵和痒螨检查确定阳性羊,设Ⅰ组:阿维菌素复方制剂2号(阿维剂量0.4mg/kg.BW.左旋剂量4mg/kg.BW);Ⅱ组:1%阿维菌素注射液0.4 mg/kg.BW;Ⅲ组:20%左旋咪唑注射液4 mg/kg.BW;Ⅳ组:左旋咪唑片剂7.5 mg/kg.BW;Ⅴ组:空白对照组,按羊的体重皮下注射或口服药物。结果Ⅰ、Ⅱ组羊用药后痒螨驱净率达100%,10 d试验羊虫卵减少率为100%和粗计驱虫率也为100%。Ⅲ组羊虫卵减少率和粗计驱虫率分别为91.3%和85%,Ⅳ组羊虫卵减少率和粗计驱虫率分别为82.7%和75%。结论阿维菌素复方制剂2号中左旋咪唑与阿维菌素混合无配伍禁忌,其驱除绵羊体内外寄生虫效果极佳。 相似文献
2.
选用伊维菌素注射剂按0.1,0.2,0.3mg/kg剂量和盐酸左旋咪唑片剂7.5,15,22.5mg/kg剂量对放牧绵羊进行驱虫试验,分别于给药后7d、14d检查效果。结果：伊维菌素组第7d消化道线虫的虫卵减少率分别为99.10%,99.18%和99.21%。14d分别为97.18%,98.91%,99.21%;肺线虫幼虫7d无明显变化,14d减少率分别为96.59%,96.51%,97.37%。左旋咪唑组第7d消化道线虫的虫卵减少率分别为67.79%,93.17%和95.52%,14d分别为54.68%,83.62%,84.30%;对肺线虫第7d幼虫减少率分别为62.76%,58.13%和45.74%,14d分别为0、72.76%,83.72%。试验表明伊维菌素注射液驱虫效果明显优于左旋咪唑片剂。 相似文献
3.
用饱和盐水浮聚法对60只云岭峻王黑山羊筛选肠道线虫感染者,共发现8种消化道线虫,分别是捻转血矛线虫、奥斯特线虫、古柏线虫、马歇尔线虫、仰口线虫、毛圆线虫、食道口线虫、夏伯特线虫,它们的感染率分别为100%、100%、100%、71.67%、86.67%、22.33%、100%、90%;体外寄生虫有软蜱和疥螨,感染率为100%和85%.从中选30只感染寄生虫的阳性山羊,分别用左旋咪唑片剂和伊维菌素注射液进行驱虫试验,间隔7 d重复用药一次.结果表明:左旋咪唑组消化道线虫的虫卵减少率平均为84.63%,对体外寄生虫无效;伊维菌素组消化道线虫的虫卵减少率平均为99%,体外寄生虫软蜱的感染率下降为13.33%,疥螨的感染率下降为3.33%;在增重上,左旋咪唑组平均日增重为48.89 g,伊维菌素组平均日增重为72.22 g,比左旋咪唑组提高47.72%;即伊维菌素注射液驱虫效果明显优于左旋咪唑片剂驱虫效果. 相似文献
4.
阿维菌素和丙硫苯咪唑对巨晰体内寄生虫的驱除试验 总被引：1，自引：0，他引：1
用丙硫苯咪唑和阿维菌素对国家一级保护野生动物巨蜥进行驱进行驱虫试验，每种药物设2个剂量组，每组6个重复。口服丙硫苯咪唑40.0mg/kg剂量组的胃肠道线虫虫卵减少率和虫卵转阴率分别为91.49%和83.33%，20.0mg/kg的剂量无效。皮下注射阿维菌素0.3mg/kg和0.6mg/kg剂量组的胃肠道线虫虫卵减少率和虫卵阴率均达100%。试验结果表明，用丙硫苯咪唑驱除巨蜥消化道线虫需较高剂量，较小剂量的阿维菌素对驱除巨蜥消化道线虫效果很好。 相似文献
5.
为验证乙酰氨基阿维菌素对内寄生虫的驱虫效果,在已经感染内寄生虫的某奶牛场特设计以下试验：随机选取20头奶牛分成试验组和对照组,分别在试验进行的当天、第7天、第14天、第21天、第28天采集每一头牛的粪便,然后分别测定粪便中的线虫虫卵数量,计算注射乙酰氨基阿维菌素后奶牛粪便中虫卵减少率,同时对两组奶牛所产的牛奶进行品质检测。结果表明,自注射乙酰氨基阿维菌素后第二周开始,试验组奶牛粪便内的线虫虫卵数量大幅度减少,而对照组奶牛粪便内的线虫虫卵数量基本保持不变;注射乙酰氨基阿维菌素后虫卵减少率也是从第二周开始大幅度增加,至第四周试验结束时达到95.08%;注射组奶牛所产的牛奶经乳品公司严格的入场检测无抗生素残留。 相似文献
6.
不同驱虫药物对奶牛消化道线虫和吸虫驱除效果的试验 总被引：7，自引：0，他引：7
本文介绍应用两种不同药物对舍饲奶牛消化道寄生的线虫和吸虫进行了驱除试验,1组奶牛投服丙硫苯咪唑,2组奶牛投服一次净打虫星。结果投药后第5天,1组奶牛的消化道线虫和吸虫虫卵减少率分别为100%和78.1%,2组的减少率分别为90.9%和87.2%;投药后第10天,1组奶牛的减少率分别为100%和18.8%,2组奶牛的减少率分别为72.7%和17.0%。从而说明,丙硫苯咪唑与一次净打虫星对奶牛消化道吸虫的驱除效果不显著,对驱除线虫有良好效果。 相似文献
7.
用猪为实验对象，分为2个实验组和1个对照组，比较了阿维菌素1%的注射液和伊维菌素1%的注射液，驱除猪体内寄生虫的效果。结果驱虫后第9天，粪便中线虫虫卵的转阴率均为100%，线虫虫卵减少率均为100%，表明阿维菌素能有效驱除猪体内线虫，且达到伊维菌素驱除体内线虫的效果。两种药物对妊娠母猪的怀孕和哺乳仔猪没有产生可见影响。 相似文献
8.
为了确定阿维菌素复方制剂1号（含丙硫苯咪唑亚砜和阿维菌素）注射液驱杀绵羊体内外寄生虫效果。通过虫卵和痒螨检查确定阳性羊,设Ⅰ为阿维菌素复方制剂1号;Ⅱ为1%阿维菌素注射液;Ⅲ为蠕能净注射液;Ⅳ为10%丙硫苯咪唑口服混悬液;Ⅴ为丙硫苯咪唑片剂;Ⅵ为空白对照组。按羊的体重皮下注射或口服药物。Ⅰ、Ⅱ组痒螨驱净率达100%;Ⅰ～Ⅴ组虫卵转阴率和粗计驱虫率均为100%;Ⅲ、Ⅳ、Ⅴ组毛民线虫虫卵减少率分别为72%、71%、71%;Ⅰ、Ⅲ、Ⅳ、Ⅴ组绦虫和肝片吸虫虫卵减少率、粗计驱虫率均达100%。阿维菌素复方制剂1号中注射液驱杀绵羊体内外寄生虫效果极佳。 相似文献
9.
验证放牧条件下伊维菌素驱虫效果,从饲养管理、放牧条件相同的一群300多只羔羊中通过粪便检查、称重从中选出体重相差不大、感染消化道线虫较为严重60只,根据感染程度均匀搭配,分为三组进行试验,每组20只用伊维菌素预混剂拌料饲喂放牧山羊,试验结果是试验组、药物对照组驱虫后3 d虫卵减少率分别是96.4%和88.7%,虫卵转阴率分别为80%和25%;驱虫后10d两组羊的虫卵减少率分别为100%和97.8%,虫卵转阴率分别为100%和85%,伊维菌素对放牧山羊消化道线虫驱虫效果优于药物左旋咪唑。 相似文献
10.
为了解牦牛主要消化道线虫对阿苯达唑的抗药性,采用粪便虫卵减少试验,将60头供试牛随机分为4组,每组15头。1～3组为试验组,第4组为阳性对照组。按照分组对试验牛逐头称重、编号、记录,1～3组分别按5、10、15mg/kg体重剂量经口投服阿苯达唑片剂,第4组给予安慰剂。给药前1d,给药后7d和14d各组试验牛逐头直肠采粪,采用饱和盐水漂浮法进行实验室检查,统计消化道线虫1g粪便中的虫卵数(EPG)。根据投药后7d和14d EPG的变化情况,奥斯特线虫7d的虫卵减少率为86.5%,90.4%,100%,14d的虫卵减少率为89.2%,93.8%,97.0%;马歇尔线虫7d的虫卵减少率为73.1%,96.2%,94.5%,14d的虫卵减少率为84.9%,98.0%,100%;细颈线虫7d的虫卵减少率为83.2%,90.4%,93.8%,14d的虫卵减少率为81.5%,93.3%,95.1%。结论:根据世界兽医寄生虫学促进协会(WAAVP)推荐的虫卵减少百分率95%置信域来判定虫体是否产生了抗药性,得出奥斯特线虫、细颈线虫和马歇尔线虫对阿苯达唑均未产生抗药性。 相似文献
11.
国产阿维菌素驱杀绵羊内外寄生虫试验 总被引：5，自引：2，他引：3
在隔离饲养的条件下,０２ｍｇ／ｋｇ 、０３ｍｇ／ｋｇ 国产阿维菌素片剂和０２ ｍｇ／ｋｇ 气雾剂对绵羊颚虱、绵羊足颚虱、消化道线虫和丝状网尾线虫的驱杀效果均达１００ ％ ;对绵羊虱蝇杀灭率分别为９０６４ ％ 、９４９９ ％ 和８７７１ ％ ;对草原革蜱的杀灭率分别为７４４２ ％ 、８４９１ ％ 和７６３２ ％ ;原园科线虫减少率分别达８３１７ ％ 、９０７６ ％ 、８５６６ ％ 。因此,在放牧条件下,推广使用阿维菌素片剂是防治内外寄生虫病的一种有效手段。 相似文献
12.
为找出能促使仔猪快速增长的免疫增强剂,将来自7窝的42头体重相当的25日龄约克仔猪随机分成A、B、C、D、E、F6组,每组7头。在25日龄、40日龄、47日龄时分别向A、B、C、D、E各组注射2mL转移因子、2mL黄芪多糖、2mL干扰素、2mL左旋咪唑及3mL黄芪多糖,F组注射2mL生理盐水作为对照。在28日龄、40日龄及63日龄分别对每头猪只称量体重。结果显示,B和E组增重在40日龄及63日龄时均极显著高于对照F组(P0.01);A组和D组增重与对照组F组相比差异不显著(P0.05);C组与对照组F组相比少增重2.05%,差异显著(P0.05)。表明黄芪多糖对仔猪增重有显著的促进作用,转移因子、左旋咪唑对仔猪增重无明显作用,干扰素能显著抑制仔猪生长。 相似文献
13.
F G Hembry J E Miller D Sims S Rodriguez L C Stagg 《American journal of veterinary research》1986,47(8):1677-1679
Levamisole, morantel, fenbendazole, or ivermectin was administered at 2-week intervals from May 1 through Sept 14, 1985, to breeding ewes (20 ewes/drug) infected with various gastrointestinal nematodes. All ewes had fewer gastrointestinal nematode eggs per gram of feces (epg) after 2 treatments, compared with pretreatment epg counts. Ewes administered ivermectin continued to have a low mean epg (0 to 3) throughout the study. The mean epg counts of ewes treated with levamisole increased from 3 to 483 during the study. This increase was similar to that of ewes treated with morantel (7 to 485 epg). The mean epg count of fenbendazole-treated ewes increased from 4 to 192 during the study. By the end of the study, the mean epg counts when expressed as a percentage of the pretreatment epg counts were 4% (ivermectin), 249% (fenbendazole), 627% (levamisole), and 630% (morantel). With the exception of the ivermectin-treated ewes, the epg count increased almost linearly in the ewes after the 2nd anthelmintic treatment. These data indicate that the gastrointestinal nematodes (including Haemonchus contortus) may have developed more resistance to levamisole and morantel than to fenbendazole. On the basis of the epg counts, resistance to ivermectin did not develop during the 4.5-month treatment period. The percentage of ewes shedding eggs after 2, 4, and 6 anthelmintic treatments was lowest for ewes treated with ivermectin (20%) and was similar (40%) for ewes treated with 1 of the other 3 anthelmintics. At the conclusion of the study, most of the ewes (90%) were shedding at least a small number of eggs, regardless of the anthelmintic treatment.(ABSTRACT TRUNCATED AT 250 WORDS) 相似文献
14.
Zoric M Sjölund M Persson M Nilsson E Lundeheim N Wallgren P 《Journal of veterinary medicine. B, Infectious diseases and veterinary public health》2004,51(6):278-284
A group of 175 newborn piglets were monitored with respect to development of abrasions and lameness. Lameness was diagnosed in 10.9% of the piglets. About every second litter was affected and around 75% of these diagnoses took place during the first 3 weeks of life. Skin lesions were present already on day 3. They increased in magnitude until day 10 and thereafter declined. They were generally bilateral and most commonly observed as abrasions over the carpal joints. Hocks, face and tails were affected in a similar way, but at lower magnitudes. Sole bruising was observed in 87% of the piglets on the third day of life, and moderate to severe lesions dominated until day 10. Thereafter the incidence decreased, indicating healing with time. Still 39% of the piglets were affected at day 17. There was a significant positive correlation between skin lesions of carpus and hock within all examination days in selected piglets with known identity (n = 48). Between day 10 and 17 significant positive correlations were found within all examination sites with exception of abdomen and teats. The offspring of sows treated against mastitis expressed more abrasions then piglets delivered by healthy sows and the mortality during the first 17 days postpartum was significantly higher among piglets delivered by sows treated for mastitis. The level of serum antibodies to Streptococcus equisimilis in eight dams decreased during the last month of gestation and a declining maternal immunity to S. equisimilis was demonstrated in all piglets (n = 47) during the first 5 weeks of life. During the first 2 weeks of life somewhat lower median levels of serum antibodies were recorded among the piglets that were treated against arthritis (n = 8). 相似文献
15.
16.
Billinis C Paschaleri-Papadopoulou E Psychas V Vlemmas J Leontides S Koumbati M Kyriakis SC Papadopoulos O 《Veterinary microbiology》1999,70(3-4):171-177
Six piglets that had survived experimental infection with encephalomyocarditis virus (EMCV) were treated with dexamethasone for a period of 5 days. The virus had not been detected in excretions of putative carriers for a period of 13–20 days before the treatment. All piglets showed a rise in cardiac isoenzyme (CK-MB) activity, from the first day of treatment, suggesting myocardial damage. Antibody titres against EMCV remained stable or slightly decreased during treatment. EMCV was isolated from blood, nasal and faecal samples from all piglets on days 2 and 3 after initiation of treatment and from various tissues of three piglets. Four contact piglets, that were housed together with the dexamethasone-treated piglets, became infected, indicating that EMCV was shed by treated piglets. It is suggested that recovered pigs may play an important role in the dissemination of EMCV. 相似文献
17.
为了研究蜂胶对母猪生产性能的影响,选择16头配种时间、胎次基本一致的长大妊娠母猪为材料,随机分成对照组和试验组。对照组只饲喂基础日粮,试验组则在基础日粮中添加蜂胶。试验从母猪妊娠81d进产房开始,到仔猪21日龄断奶后7d结束。研究结果表明,与对照组相比,试验组仔猪断奶重平均提高0.62kg,差异极显著(P<0.01);成活率提高4.51%,差异显著(P<0.05);在哺乳和断奶前7d,试验组仔猪腹泻率分别比对照组低1.37%(P<0.05)、2.96%(P<0.01)。因此,蜂胶对提高母猪生产性能有较大促进作用。 相似文献
18.
本文测定了阿维菌素和甲氨基阿维菌素苯甲酸盐（简称＂甲维盐＂）4种杀虫剂制剂对家蚕的急性食下毒性和残毒期,结果表明：对3龄起蚕的LC50值分别为阿维菌素乳油7.2343×10-4mg/L,阿维菌素水乳剂7.6512×10-4mg/L,甲维盐微乳剂8.5940×10-4mg/L,甲维盐乳油14.0112×10-4mg/L。阿维菌素和甲维盐4种制剂的相同质量浓度（13.33 mg/L）稀释液喷洒桑树,在桑叶上的残毒期分别为3.2%阿维菌素乳油2400倍约为50 d,1.8%阿维菌素水乳剂1350倍、2.3%甲维盐乳油1725倍约为60 d,2.2%甲维盐微乳剂1650倍＞60 d;阿维菌素类4种制剂对家蚕的急性食下毒性极强,处理间差异较小,但在桑叶上的残毒期很长,处理间差异较大。 相似文献
19.
Lameness in piglets up to nine weeks old was studied in a research station herd for four years; 9411 piglets were born alive, of which 9.8 per cent were treated for lameness. In litters born to gilts, 9.9 per cent of the piglets were treated for lameness, in litters born to sows of parity 3, 11.4 per cent of the piglets were treated, but in litters born to sows of parity 4 to 7 the proportion of piglets treated for lameness decreased to about 8 per cent. Around 75 per cent of all cases were observed in piglets less than three weeks old; the incidence risk of lameness decreased from 2.7 per cent during the first week of life to 0.3 per cent after weaning. The average weight of affected piglets was reduced by approximately 8 per cent at nine weeks of age. There was no overall association between lameness and sex or birth weight within sex. The mortality among lame gilts was higher at all ages than among healthy gilts, but among barrows a higher mortality was observed only during the late suckling period. Litters with 12 or more piglets had a higher incidence of lameness. Clinical signs of disease in the sow and whether the piglets were given an intramuscular injection of 200 mg of iron on their second, third or fourth day of life had no effect on the incidence of lameness. 相似文献
20.
Yoo HS Lee BJ Chang BS Lee YS Park BK 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2001,63(1):67-72
A field trial was conducted to evaluate effect of enrofloxacin-Na against pathogens related to the respiratory and alimentary diseases in eighty suckling piglets (6-7 days old) and eighty weanling piglets (5-6 weeks old). Respective twenty of the suckling and weanling piglets were assigned to each of 4 experimental groups; control (non-treated), clinical injection dose (CID), 2x clinical injection dose (2CID). and premix. A 0.05 ml (2.5 mg) of enrofloxacin-Na injection (5% solution, 1 ml) per kg body weight of piglets as CID was injected intramuscularly for 3 days and the clinical signs were observed for 9 days. The premix (150 ppm) of enrofloxacin-Na was administered with feed for 7 days ad libitum and the clinical signs were observed for 13 days. The enrofloxacin-Na-treated piglets showed a higher increase in body weight and a lower feed per gain than the control piglets. In addition, the treatment of enrofloxacin-Na, regardless of the route of administration, decreased the incidence rate of diarrhea in suckling piglets and respiratory symptoms in weanling piglets. The isolation index of E. coli and Cl. perfringens during the treatment periods was also lowered by the enrofloxacin-Na treatment in both suckling and weanling piglets. The antibiotics was also evaluated as safe locally and whole bodily as treated by injection or feeding. These results indicate that the newly developed antibiotics, enrofloxacin-Na, is very useful for the prevention and therapy of swine diseases in the pig industry. 相似文献