共查询到20条相似文献，搜索用时 31 毫秒
1.
2.
Abutarbush SM O'Connor BP Clark C Sampieri F Naylor JM 《The Canadian veterinary journal. La revue veterinaire canadienne》2004,45(4):315-317
Two horses had a history of ataxia and weakness or recumbency. One recovered and was diagnosed with West Nile virus (WNV) infection by serologic testing. The other was euthanized; it had meningoencephalomyelitis, WNV was detected by polymerase chain reaction. West Nile virus infection is an emerging disease. Year 2002 is the first year in which cases have been seen in Saskatchewan. 相似文献
3.
4.
5.
Isabelle Lanthier Michel Hébert Donald Tremblay Josée Harel André D Dallaire Christiane Girard 《Journal of veterinary diagnostic investigation》2004,16(4):326-329
A case of West Nile virus (WNV) infection in a captive 4-month-old Arctic wolf (Canis lupus) is described. The animal had vomiting, anorexia, and ataxia before death. Histopathology revealed multifocal severe renal lymphoplasmacytic vasculitis, mostly affecting small arterioles, with fibrinoid degeneration of some vessel walls. Many small foci of gliosis were detected in the cerebral cortex. West Nile virus was demonstrated in the kidneys and cerebrum by immunohistochemistry and polymerase chain reaction. The described renal changes represent a novel pathological finding of WNV infection. 相似文献
6.
7.
8.
西尼罗热病毒RT-PCR检测方法的建立 总被引：3，自引：0，他引：3
参考Genebank发表的西尼罗热病毒(West Nile virus，WNV)E糖蛋白基因序列，自行设计合成一对引物，对WNV进行RT—PCR扩增，产物经琼脂糖电泳分析，呈现一条约400bp的条带，将其克隆入pMD18-T—Vector载体中，并进行序列测定，与已发表的WNV基因比较发现，核苷酸的同源性为99．7％，证实为WNV的E基因，通过对样品多次检测，都能扩增出一条约400bp的条带，表明该方法比较稳定。 相似文献
9.
10.
West African Dwarf Sheep inoculated sequentially with two flaviviruses: yellow fever and Dakar bat or West Nile and yellow fever viruses, developed neutralizing (N) and haemagglutination inhibiting (HI) antibodies to several flaviviruses; dengue type 1, dengue type 2, yellow fever, West Nile and Wesselsbron viruses. Experimental infection of these animals with the indigenous strain of Wesselsbron virus resulted in the modification of the clinical disease. The disease was reduced in severity and there was complete absence of, or marked reduction in the level and duration of circulating virus and fever. Seronegative animals infected with the same strain of Wesselsbron virus developed the classical disease characterized by a high fever, anorexia, leucopenia and a high level of viraemia. The absence of clinical reports of Wesselsbron disease and lack of other isolations of the virus from Nigeria could possibly be explained by the presence of the flavivirus group antibodies in domestic animal sera. 相似文献
11.
Monaco F Savini G Calistri P Polci A Pinoni C Bruno R Lelli R 《Research in veterinary science》2011,91(2):321-326
For the second consecutive year a West Nile disease (WND) epidemic has affected Italy causing disease in horses and humans. The infection re-occurred in the same places of the 2008 and moved westerly and southerly involving new areas and regions. The whole genome sequence of the Italian 2009 West Nile disease isolate (WNDV) was compared with those responsible for the 2008 WND outbreaks. The epidemiological findings of the two years of epidemic were compared as well. The high identity between 2008 and 2009 WNV strains (>99%), the earlier virus circulation in 2009 and the re-occurrence of the disease starting from the bordering infected areas reached by the infection in the previous year, strongly support the hypothesis of the overwintering of the virus and the endemisation to local host populations. 相似文献
12.
13.
14.
A 42-day study was conducted to assess the impact of three West Nile virus vaccines given either as separate injections or incorporated with their counterpart equine encephalitis and tetanus vaccines on serological responses under field use conditions. Two hundred forty mature, West Nile virus seronegative (<4) horses were followed serologically pre- and postprimary and secondary vaccination with six different vaccination programs, all including West Nile virus antigens. Forty horses were unvaccinated sentinel horses. All vaccines stimulated both a primary and secondary (booster) response to vaccination that was significantly higher than that of seronegative controls. However, inclusion of West Nile virus with equine encephalitis viruses and tetanus toxoid in vaccines had a significant detrimental impact on West Nile virus serum neutralization antibody production to both the primary and secondary vaccinations. 相似文献
15.
16.
Clinical presentation of West Nile disease in horses is variable, but ataxia, weakness and muscle fasciculations are often observed, sometimes with abnormal behaviour, teeth grinding and bruxism. Practitioners should be aware that horses are more sensitive to infection than man and serve as sentinels for an early warning of West Nile virus circulation in a given area. This early warning allows the implementation of preventive and control measures such as vaccination of horses and mosquito control. 相似文献
17.
18.
Sheep are susceptible to at least 5 of the 10 flaviviruses known to be present in South Africa. Sheep, 7-9 months of age, injected with Wesselsbron, West Nile, Banzi, Uganda-S and AR 5189 (an unidentified virus related to Banzi and Uganda-S), responded with a moderate febrile reaction, a low grade viraemia of short duration and the production of virus neutralizing antibodies. The most pronounced manifestations of infection were encountered in pregnant ewes. Infection with West Nile, Banzi and AR 5189 resulted in abortion, stillbirth and neonatal death, characterized by congenital abnormalities of the brain. 相似文献
19.
Erik K. HOFMEISTER 《Integrative zoology》2011,6(3):279-289
West Nile virus, a mosquito‐vectored flavivirus of the Japanese encephalitis serogroup, was first detected in North America following an epizootic in the New York City area in 1999. In the intervening 11 years since the arrival of the virus in North America, it has crossed the contiguous USA, entered the Canadian provinces bordering the USA, and has been reported in the Caribbean islands, Mexico, Central America and, more recently, South America. West Nile virus has been reported in over 300 species of birds in the USA and has caused the deaths of thousands of birds, local population declines of some avian species, the clinical illness and deaths of thousands of domestic horses, and the clinical disease in over 30 000 Americans and the deaths of over 1000. Prior to the emergence of West Nile virus in North America, St. Louis encephalitis virus and Dengue virus were the only other known mosquito‐transmitted flaviviruses in North America capable of causing human disease. This review will discuss the North American experience with mosquito‐borne flavivirus prior to the arrival of West Nile virus, the entry and spread of West Nile virus in North America, effects on wild bird populations, genetic changes in the virus, and the current state of West Nile virus transmission. 相似文献
20.
An outbreak of West Nile virus-associated disease in domestic geese (Anser anser domesticus) upon initial introduction to a geographic region, with evidence of bird to bird transmission 
下载免费PDF全文
下载免费PDF全文 Austin RJ Whiting TL Anderson RA Drebot MA 《The Canadian veterinary journal. La revue veterinaire canadienne》2004,45(2):117-123
West Nile virus activity in Manitoba was documented for the first time by the collection of an infected crow found on July 8, 2002, in Winnipeg. West Nile virus was identified as the cause of death for a large number of domestic geese at a single farm in southern Manitoba in August. Of the 5 differently aged cohorts on the affected farm, which included 2 breeding flocks and 3 growing flocks, the 6-week-old cohort was most severely affected with 692 of 2731 goslings dying within a 10-day period. Seroprevalence of West Nile virus in 2 clinically affected and recovered juvenile cohorts was 98% and 100%. In breeding geese without clinical disease, seroprevalence was 90% for 15-month-old birds and 10% for 5-year-old birds. Seroreaction in 3 of 4 cohorts tested exceeded what would be expected by mosquito transmission alone. 相似文献