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近年来,随着中国畜牧业的持续发展,中国牛病毒性腹泻的流行正在增加,严重阻碍了中国畜牧业的健康发展,造成了巨大的经济损失,同时这种病广泛分布在鹿的养殖场,牛病毒性腹泻病毒是鹿难治性腹泻的主要病原体。1 BVDV的传播和现状1.1 BVDV的传播分离和判断BVDV的方法有很多,一般来说,BVDV是由牛内腔、血液、肾脏淋巴结以及肠间膜淋巴结的分泌来传达的,分离是由胎儿牛肾脏细胞和小牛精巢细胞的接种决定的。 相似文献
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《畜牧兽医科技信息》2016,(5)
正牛病毒性腹泻病毒(Bovine viral diarrhoea virus,BVDV),为黄病毒科瘟病毒属成员,该病可导致患病牛白细胞减少、精神消沉、腹泻、奶牛减产,严重时可导致患病母牛流产、产出畸形胎儿并可导致新生牛死亡的一种传染病,并能导致二次感染及细菌感染,出生后存活下来的犊牛可终身带毒并成为传染源,一旦发病,往往给牛场带来巨大损失。1牛病毒性腹泻的流行现状BVDV可在所有牛群中传播,呈高度传染性;病牛腹泻 相似文献
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正牛病毒性腹泻(BVD)是由黄病毒科、瘟病毒属的牛病毒性腹泻病毒(BVDV)引起的一种复杂的传染病性疾病。该病常见的有发烧,黏膜溃烂,溃疡,腹泻,怀孕母牛流产,牛体内的白细胞减少或者是畸形牛胚胎等现象~([1])。此病广泛分布于世界各地,给奶牛业的发展带来较大的经济损失。近年来,我国BVD血清流行病学调查结果表明, 相似文献
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Tropical Animal Health and Production - Bovine viral diarrhea virus (BVDV), a prominent viral pathogen worldwide, causes substantial economic losses in the cattle industry. BVDV comprises two... 相似文献
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牛病毒性腹泻／黏膜病（BVD）是由牛病毒性腹泻病毒（BVDV）引起的一种极为复杂,呈多种临床症状类型表现的疾病。目前,该病毒在世界范围内广泛分布,是造成全球乳／肉牛业经济损失的主要病原。本文针对我国牦牛BVD的发病状况进行分析,并对今后牦牛BVD防控进行了展望。 相似文献
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Natural infection of pigs with bovine viral diarrhea virus and its differential diagnosis from hog cholera. 总被引：1，自引：0，他引：1
E A Carbrey W C Stewart J I Kresse M L Snyder 《Journal of the American Veterinary Medical Association》1976,169(11):1217-1219
Natural infection of pigs with bovine viral diarrhea virus (BVDV) through contact with infected cattle has caused problems in diagnosing hog cholera (HC). Low cross-reacting serum antibody titers against HC caused by BVDV infection were found in clinically normal pigs as well as those suspected of having HC. Bovine viral diarrhea virus was isolated from specimen tissues and initially identified as HC virus (HCV), using the fluorescent antibody cell culture technique. Additional cell cultures, as well as pig and calf trials, were necessary to identify it as BVDV. The isolate caused clinical signs of illness in the calves, whereas the pigs remained healthy. Bovine viral diarrhea virus may be detected in tissue sections or isolated in cell cultures and confirmed as HCV, using the HC fluorescent antibody conjugate. Laboratories performing the neutralization test for HC should use discretion when interpreting HC titers unless BVD titers are determined on the same serums. 相似文献
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Diagnosis of natural exposure to bovine viral diarrhea in a vaccinated herd by measuring extended antibody titers against bovine viral diarrhea virus 
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下载免费PDF全文 Two abortions occurred in a 150-head commercial cow-calf herd. Bovine viral diarrhea was suspected and confirmed by measuring extended titers against bovine viral diarrhea virus (BVDV) in a sample of 15 breeding females. Fifteen were sero-positive and 11 had significantly high titers (1:972-1:8748), likely due to natural exposure to cattle persistently infected with BVDV. 相似文献
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Bovine viral diarrhea virus (BVDV) is one of the most important pathogenic viruses which mainly causes bovine viral diarrhea disease (BVD). BVDV can not only cause serious clinical symptoms, but also lead to decrease of immunity of livestock and infect other pathogens, resulting in significant increase of morbidity and mortality of sick animals, and causes significant losses to the cattle industry. With the development of molecular biology theory and technology in recent years, the research on BVDV has been deepening, and some new understandings have been made to the molecular biology of the virus. In this paper, the progress of molecular biology of BVDV in recent years is described from three aspects of the composition and function of virus, the epidemic situation of BVDV gene and the genetic and mutation of BVDV gene. 相似文献
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牛病毒性腹泻病毒（bovine viral diarrhea virus,BVDV）是导致牛腹泻的重要致病病毒之一,BVDV感染不仅能造成严重的临床症状,且可导致患畜的免疫力降低从而感染其他病原,致使患病动物的发病率和死亡率大大增加,给养牛业造成重大的损失。随着近年来分子生物学相关理论及技术不断发展,对于BVDV的研究逐渐深入,人们对该病毒的分子生物学方面有了一些新的了解,作者主要从BVDV的病毒粒子结构组成及功能、国内外的流行情况和BVDV基因的遗传与变异情况3个方面阐述近几年BVDV的分子生物学研究进展。 相似文献
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Transmission of Bovine viral diarrhea virus 1b to susceptible and vaccinated calves by exposure to persistently infected calves 下载免费PDF全文
下载免费PDF全文 Robert W. Fulton Robert E. Briggs Julia F. Ridpath Jeremiah T. Saliki Anthony W. Confer Mark E. Payton Glenn C. Duff D.L. Step D.A. Walker 《Canadian journal of veterinary research》2005,69(3):161-169
Bovine viral diarrhea virus (BVDV) persistently infected (PI) calves represent significant sources of infection to susceptible cattle. The objectives of this study were to determine if PI calves transmitted infection to vaccinated and unvaccinated calves, to determine if BVDV vaccine strains could be differentiated from the PI field strains by subtyping molecular techniques, and if there were different rates of recovery from peripheral blood leukocytes (PBL) versus serums for acutely infected calves. Calves PI with BVDV1b were placed in pens with nonvaccinated and vaccinated calves for 35 d. Peripheral blood leukocytes, serums, and nasal swabs were collected for viral isolation and serology. In addition, transmission of Bovine herpes virus 1 (BHV-1), Parainfluenza-3 virus (PI-3V), and Bovine respiratory syncytial virus (BRSV) was monitored during the 35 d observation period. Bovine viral diarrhea virus subtype 1b was transmitted to both vaccinated and nonvaccinated calves, including BVDV1b seronegative and seropositive calves, after exposure to PI calves. There was evidence of transmission by viral isolation from PBL, nasal swabs, or both, and seroconversions to BVDV1b. For the unvaccinated calves, 83.2% seroconverted to BVDV1b. The high level of transmission by PI calves is illustrated by seroconversion rates of nonvaccinated calves in individual pens: 70% to 100% seroconversion to the BVDV1b. Bovine viral diarrhea virus was isolated from 45 out of 202 calves in this study. These included BVDV1b in ranch and order buyer (OB) calves, plus BVDV strains identified as vaccinal strains that were in modified live virus (MLV) vaccines given to half the OB calves 3 d prior to the study. The BVDV1b isolates in exposed calves were detected between collection days 7 and 21 after exposure to PI calves. Bovine viral diarrhea virus was recovered more frequently from PBL than serum in acutely infected calves. Bovine viral diarrhea virus was also isolated from the lungs of 2 of 7 calves that were dying with pulmonary lesions. Two of the calves dying with pneumonic lesions in the study had been BVDV1b viremic prior to death. Bovine viral diarrhea virus 1b was isolated from both calves that received the killed or MLV vaccines. There were cytopathic (CP) strains isolated from MLV vaccinated calves during the same time frame as the BVDV1b isolations. These viruses were typed by polymerase chain reaction (PCR) and genetic sequencing, and most CP were confirmed as vaccinal origin. A BVDV2 NCP strain was found in only 1 OB calf, on multiple collections, and the calf seroconverted to BVDV2. This virus was not identical to the BVDV2 CP 296 vaccine strain. The use of subtyping is required to differentiate vaccinal strains from the field strains. This study detected 2 different vaccine strains, the BVDV1b in PI calves and infected contact calves, and a heterologous BVDV2 subtype brought in as an acutely infected calf. The MLV vaccination, with BVDV1a and BVDV2 components, administered 3 d prior to exposure to PI calves did not protect 100% against BVDV1b viremias or nasal shedding. There were other agents associated with the bovine respiratory disease signs and lesions in this study including Mannheimia haemolytica, Mycoplasma spp., PI-3V, BRSV, and BHV-1. 相似文献
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Christopher C L Chase Gamal Elmowalid Ausama A A Yousif 《Veterinary Clinics of North America: Food Animal Practice》2004,20(1):95-114
Bovine viral diarrhea virus (BVDV) is one of the major immuno-suppressive viruses of cattle. The effect on the innate and acquired immune system is unique and results in dramatic immune dysfunction. BVDV infection also has the ability to cause persistent infection (PI) in the developing fetus. This Pl syndrome creates a requirement for high levels of BVDV immunity from vaccines to prevent these infections. BVDV vaccines and their future development continue to be an enigma in the control of BVDV. 相似文献
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Hou Peili Zhao Guimin Wang Hongmei He Hongbin 《Tropical animal health and production》2019,51(4):791-798
Tropical Animal Health and Production - Bovine viral diarrhea virus (BVDV) is a worldwide spreading pestivirus affecting cattle and other ruminants; however, there have been few reports on... 相似文献