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胆盐和游离脂肪酸影响离体小肠细胞类胡萝卜素吸收的研究 总被引:6,自引:0,他引:6
用黄鸡小肠细胞进行了 β-胡萝卜素和黄体素的体外吸收试验 ,研究类胡萝卜素浓度、胆盐和游离脂肪酸对这两种类胡萝卜素吸收的影响。结果发现 :β-胡萝卜素和黄体素的吸收均呈浓度依赖性 ;牛磺胆酸钠极显著促进黄鸡离体小肠细胞类胡萝卜素的吸收(P<0.01) ,其促进 β-胡萝卜素和黄体素吸收的最佳浓度分别为3mM和10mM ;游离脂肪酸极显著促进了类胡萝卜素的吸收(P<0.01) ,其中油酸对类胡萝卜素的促吸收作用大于硬脂酸 ,促进 β-胡萝卜素和黄体素吸收的最佳油酸/硬脂酸比率分别为100 :0和3 :1。牛磺胆酸钠和游离脂肪酸影响 β-胡萝卜素吸收的动态变化模式与它们对黄体素的显著不同 相似文献
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利用体外法研究了浓度、温度、吐温20(Tween20,下同)、根皮素对鸡离体小肠细胞对黄体素和一切萝卜素吸收的影响。结果表明:黄体素和胡萝卜素的吸收呈浓度依赖性,培养温度对两者吸收无影响(P>0.05)。蛋鸡离体小肠细胞对两者的吸收方式可能为被动扩散;Tween20抑制了两种类胡萝卜素的吸收,其中对黄体素抑制作用较大;根皮素促进黄体素的吸收而抑制胡萝卜素的吸收。另外对蛋黄中色素分析发现其中主要沉积叶黄素。 相似文献
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山羊对β-胡萝卜素与叶黄素吸收的研究 总被引:1,自引:0,他引:1
通过山羊空肠瘘管进行灌注试验 ,并结合前腔静脉采血 ,研究山羊对类胡萝卜素(β-胡萝卜素与叶黄素)的吸收。试验发现 :随灌注时间延长 ,在同一浓度下山羊对类胡萝卜素的吸收量呈上升趋势 ,血清中叶黄素与 β-胡萝卜素浓度分别在灌注后2小时与2.5小时达到峰值 ,而VA的浓度仅略有降低 ;山羊对两种类胡萝卜素的吸收均呈浓度依赖性 ,但吸收率保持不变 ,血清中类胡萝卜素的浓度随其在灌注液中浓度的升高而升高 ,但VA的浓度随灌注液中β-胡萝卜素浓度的升高而基本保持稳定 ;游离脂肪酸促进了两种类胡萝卜素的吸收 ,提高了血清内 β-胡萝卜素与VA的浓度 ,降低了叶黄素的浓度 相似文献
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类胡萝卜素的营养学研究进展 总被引:4,自引:0,他引:4
类胡萝卜素不仅是维生素A的前体,还是一种天然的着色剂和抗氧化剂,具有免疫调节和抗癌作用,近年来还发现类胡萝卜素对畜牧生产有重要意义。但关于畜禽类胡萝卜素的吸收机制尚存在认识上分歧,而且类胡萝卜在动物体内的吸收受到各种因素的影响。本文对类胡萝卜素的营养学研究进展一概要综述。 相似文献
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铬是动物机体必需微量元素之一,它可作为葡萄糖耐受因子的组成成分,协助胰岛素发挥生理功能。本文主要综述铬的理化特性、吸收、排泄和代谢。 相似文献
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为探讨饲料中添加砷制剂对小鼠铁吸收的影响,45只小鼠被随机分为3组,各组在基础日粮中分别添加0,40,80mg/kg砷(以洛克沙胂形式),试验期30d。试验结束后,收取各组粪便和组织器官测定铁含量。结果显示,与对照组相比,40mg/kg砷组铁表观吸收率提高14.57%,80mg/kg砷组铁表观吸收率则降低了14.93%;40mg/kg砷组小鼠肝脏、肾脏、脾脏、小肠和腿肌铁含量显著升高(P〈O.05),80mg/kg砷组则显著降低(P〈O.05);但两组分别于停砷后5,7d,组织器官铁恢复正常水平。这表明40mg/kg砷水平可促进铁的吸收,相反80mg/kg砷水平则抑制铁的吸收。 相似文献
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洛美沙星(Lomefloxacin)透皮吸收搽剂中氮酮的最佳浓度 总被引:4,自引:0,他引:4
应用洛美沙星搽剂作为模型药物,采用离体鼠皮,研究了氮酮(Azone)在0%,1%,3%,5%,7%浓度时对洛美沙星透皮吸收的影响。试验结果表明,氮酮在洛美沙星透皮吸收搽剂中最佳浓度为4.01%。 相似文献
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Nix BE Leib MS Zajac A Zarakas K 《Veterinary clinical pathology / American Society for Veterinary Clinical Pathology》1993,22(1):10-16
Nine combinations of dosages and concentrations of D-xylose were given orally to eight clinically normal, immature dogs. The concentrations and dosages of D-xylose consisted of 5%, 10%, and 20% at 250 mg/kg, 500 mg/kg, and 750 mg/kg. Serum samples were collected at 0, 30, 60, 90, 120, and 180 minutes. Serum xylose was quantitated using the phloroglucinol microassay technique. A peak in serum xylose concentration was seen for each treatment combination at 60 or 90 minutes after dosing. The dosage effect was important in influencing serum xylose values (P < 0.0001). As the test solution dosages increased from 250 mg/kg to 500 mg/kg and 750 mg/kg, serum xylose values (when dosage was analyzed over the length of the entire test) rose linearly (R(2) = 0.98). The treatment combinations of 5% and 20% xylose solutions dosed at 750 mg/kg produced the highest serum xylose values at the 60- and 90-minute peak intervals. The independent effect of concentration was significant (p < 0.001) but was overridden by the stronger dosage effect. Serum xylose concentrations varied little statistically (p > 0.05) when the 5%, 10%, and 20% solutions were compared at a specific dosage. 相似文献
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Vladimíra Oceov Remigius Chizzola Giovanna Battelli Jana Pisarcikova Stefan Faix Francesco Gai Iveta Placha 《Journal of animal physiology and animal nutrition》2019,103(1):204-209
Plant compounds occurring in phytogenic feed additives are involved in different pharmacological activities in the animal organism. Since the digestive tract acts as a first line of defence against foreign compounds, it is necessary to outline its response to dietary supplementation with bioactive plant components. Little information is available on the bioactivity of thymol as the main bioactive compound of Thymus vulgaris L. essential oil (TEO). The main objective of the present study was to provide a detailed view of the concentrations of thymol in plasma and the content of individual intestinal segments (duodenum, jejunum, ileum, caecum and colon) of broiler chickens after 4 weeks of dietary supplementation with different TEO concentrations. 32 one‐day old Ross 308 hybrid broilers were randomly divided into four dietary treatment groups (0.00%, 0.01%, 0.05%, 0.1% w/w of TEO in the diet). Thymol concentrations in the duodenal chyme presented around 7% on average from the thymol amount administered in the feed. A significantly increased thymol amount was observed after 0.1% TEO addition to the diet compared with 0.01% TEO enrichment in the duodenal wall and gut content of jejunum, ileum, caecum and colon (p < 0.05). Thymol levels in the colon were significantly higher than in the ileum and about 1.7 times higher on average than those in the caecum. Significant coefficient of correlation was observed between thymol concentrations in plasma and feed, gut content of all intestinal segments as well as duodenal wall. Our results point to intensive thymol absorption in the initial sections of the digestive tract. In the current study, the role of intestine in biotransformation of thymol was observed, and it would be desirable to investigate whether thymol itself or thymol metabolites are responsible for beneficial effects in intestine. 相似文献
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