共查询到19条相似文献，搜索用时 187 毫秒
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《养殖与饲料．饲料世界》2020,(3)
小反刍兽疫(PPR)又称羊瘟、小反刍兽假牛瘟等,是由小反刍兽疫病毒(PPRV)引起的一种急性病毒性传染病。本病主要感染山羊、绵羊等小反刍动物,常呈急性发作,病死率高。日常要做好疫情排查和监测工作,一旦确诊小反刍兽疫,要按照国家有关规定,采取紧急强制性措施,对患病羊和同群羊进行扑杀。同时,采用小反刍兽疫活疫苗对山羊、绵羊等小反刍动物进行免疫接种,能有效防控小反刍兽疫的发生。 相似文献
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小反刍兽疫分子生物学研究进展 总被引：2，自引：1，他引：1
小反刍兽疫(peste des petits ruminants,PPR)是由小反刍兽疫病毒(peste des petits ruminants virus,PPRV)引起的一种急性、烈性、接触性传染病。山羊高度易感;牛、猪等动物也可以感染带毒,野生动物偶有发生。作者主要介绍了小反刍兽疫病毒各基因结构特点,6种结构蛋白的功能,以及小反刍兽疫的诊断技术等方面的最新研究进展。 相似文献
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小反刍兽疫(PPR),曾被称小反刍兽伪牛瘟、小反刍兽瘟疫、山羊瘟病、绵羊和山羊瘟疫,胃肠炎-肺炎综合征等,是由小反刍兽疫病毒(PPRV)引起的一种小反刍兽类的急性、烈性接触性传染病[1]. 相似文献
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小反刍兽疫(PPR)是一种由小反刍兽疫病毒引起的疾病,主要感染山羊和绵羊。2021年为加快推进小反刍兽疫无疫区建设,实现小反刍兽疫非免疫无疫区建设标准,长沙市某县拟在本地开展小反刍兽疫退出强制免疫风险评估。通过对小反刍兽疫监测流调、危害识别、风险路径的确定和风险因素层级评估等方法进行的定性风险评估初步显示,在该地取消小反刍兽疫强制免疫后可能会发生小反刍兽疫的风险等级为中。在风险管理措施上,提出该地退出强制免疫应推迟一年,重点完善政策支持、加强监测排查、加强检疫监管、强化培训宣传等建议。 相似文献
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《中国畜牧兽医文摘》2016,(12)
<正>孟连县地处边境,国境线长133.399km,境外是小反刍兽疫、牛"W"病、高致病性禽流感、疫病等常发区。随着养羊业的快速发展,羊只及产品异地交易等,使疫病传播有了可乘之机。为做好小反刍兽疫防控工作,本文通过对小反刍兽疫病原、流行特征、临床症状等分析,提出相应的防控措施。1病原体小反刍兽疫(也称羊瘟)是由副黏病毒科麻疹病毒属小反刍兽疫病毒引起的以发热、口炎、腹泻、肺炎为特诊的一种急性病 相似文献
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小反刍兽疫研究现状 总被引：1，自引：0，他引：1
小反刍兽疫(Peste des petits ruminants,PPR)是由小反刍兽疫病毒(Peste des petits ruminants virus,PPRV)引起的一种主要感染小反刍动物的急性、接触性传染病,发病率、死亡率高.近年来,小反刍兽疫(PPR)呈扩散的趋势,成为重要的跨国动物传染病之一,我国周边国家频繁器发该病.2007年7月25日暴发于西藏自治区日土县的我国首例小反刍尊疫疫情,更是对我国如何做好该病的防控工作提出了新的要求和挑战.为了增强广大兽医工作者和相关人士对本病的认识,文中就小反刍兽疫的病原学、流行病学、临床症状、病理特征以及诊断方法等方面的研究现状进行了综述. 相似文献
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Khandelwal A Renukaradhya GJ Rajasekhar M Sita GL Shaila MS 《Veterinary immunology and immunopathology》2011,140(3-4):291-296
Peste des petits ruminants (PPR) is an acute, highly contagious disease of small ruminants caused by a morbillivirus, Peste des petits ruminants virus (PPRV). The disease is prevalent in equatorial Africa, the Middle East, and the Indian subcontinent. A live attenuated vaccine is in use in some of the countries and has been shown to provide protection for at least three years against PPR. However, the live attenuated vaccine is not robust in terms of thermotolerance. As a step towards development of a heat stable subunit vaccine, we have expressed a hemagglutinin-neuraminidase (HN) protein of PPRV in peanut plants (Arachis hypogea) in a biologically active form, possessing neuraminidase activity. Importantly, HN protein expressed in peanut plants retained its immunodominant epitopes in their natural conformation. The immunogenicity of the plant derived HN protein was analyzed in sheep upon oral immunization. Virus neutralizing antibody responses were elicited upon oral immunization of sheep in the absence of any mucosal adjuvant. In addition, anti-PPRV-HN specific cell-mediated immune responses were also detected in mucosally immunized sheep. 相似文献
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Chunsheng Yin Weiye Chen Qianqian Hu Zhiyuan Wen Xijun Wang Jinying Ge Qianqian Yin Haibing Zhi Chun Xia Zhigao Bu 《Veterinary research》2014,45(1):62
Peste des petits ruminants (PPR) and foot-and-mouth disease (FMD) are both highly contagious diseases of small domestic and wild ruminants caused by the PPR virus (PPRV) and the FMD virus (FMDV). In this study, a recombinant PPRV expressing the FMDV VP1 gene (rPPRV/VP1) was generated and FMDV VP1 expression did not impair replication of the recombinant virus in vitro and immunogenicity in inducing neutralizing antibody against PPR in goats. Vaccination with one dose of rPPRV/VP1 induced FMDV neutralizing antibody in goats and protected them from challenge with virulent FMDV. Our results suggest that the recombinant PPRV expressing the FMDV VP1 protein is a potential dual live vectored vaccine against PPRV and FMDV. 相似文献
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2007年小反刍兽疫(PPR)在我国西藏首次暴发,在西藏和新疆部分地区使用PPR Nigeria 75/1疫苗株制造的疫苗进行免疫接种。为明确疫苗的安全性,中国兽医药品监察所国家牛瘟参考实验室对其安全性能进行了系统评价。健康易感山羊、绵羊及怀孕山羊、怀孕绵羊按不同剂量接种疫苗后,均未观察到异常临床反应;怀孕母羊所产羔羊数量与对照组无明显差异。疫苗对小白鼠、豚鼠的非特异性安全试验表明,所有接种动物均健活。结果表明该疫苗安全性良好,可在田间大规模使用。 相似文献
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Fuxiao Liu Xiaodong Wu Wenhua Liu Lin Li Zhiliang Wang 《Veterinary research communications》2014,38(4):307-322
Peste des petits ruminants (PPR) is an acute or subacute, highly contagious viral disease of small ruminants, characterized by fever, oculonasal discharges, stomatitis, diarrhoea and pneumonia. This disease is included in the OIE (Office International des Epizooties) list of notifiable terrestrial animal diseases. PPR was first described in the early 1940s in Côte d′Ivoire, and at present, PPR is mainly circulating in Western and Central Africa, the Arabian Peninsula and Southern Asia. Peste des petits ruminants virus (PPRV), the etiological agent of PPR, is classified into the genus Morbillivirus in the family Paramyxoviridae, as its biological and physicochemical features are closely related to the other morbilliviruses. The first homologous PPR vaccine was developed by an artificially attenuated PPRV, named as Nigeria 75/1, which has been widely used in the production of live attenuated vaccines to protect small ruminants. A new generation of PPR vaccine candidates can be genetically modified to differentiate infected from vaccinated animals (DIVA), which nevertheless is difficult to achieve by conventional vaccines. In this review, we systematically discussed a broad range of vaccines against PPR, including commercially available vaccines and potential vaccine candidates, and further DIVA strategies for immunization with the new generation vaccines. 相似文献
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Prion这一术语是Prusiner提出的,其中Pr源自英文蛋白质(protein),i源自英文传染性的(infec-tious),on意指粒子(particle)。Prions病也称为传染性海绵状脑病(transmissible spongiform enceph-alopathies,TSEs),是发生于动物与人类的一种致命性神经退行性疾病(Attwood等,2000)。TSEs包括疯牛病(mad cow disease,MCD),即牛海绵状脑病(bovine spongiform encephalopathy,BSE)、羊瘙痒症(scrapie)、克-雅氏病(creutzfeldt-jakob dis-ease,CJD)、GSS综合征(gersrmann-straussler-scheikerg disease,GSS)和致死性睡眠综合征(fatalfamil… 相似文献