共查询到20条相似文献，搜索用时 44 毫秒
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Timoney JF 《Veterinary research》2004,35(4):397-409
Streptococci pathogenic for the horse include S. equi (S. equi subsp. equi), S. zooepidemicus (S. equi subsp. zooepidemicus), S. dysgalactiae subsp. equisimilis and S. pneumoniae capsule Type III. S. equi is a clonal descendent or biovar of an ancestral S. zooepidemicus strain with which it shares greater than 98% DNA homology and therefore expresses many of the same proteins and virulence factors. Rapid progress has been made in identification of virulence factors and proteins uniquely expressed by S. equi. Most of these are expressed either on the bacterial surface or are secreted. Notable examples include the antiphagocytic SeM and the secreted pyrogenic superantigens SePE-I and H. The genomic DNA sequence of S. equi will greatly accelerate identification and characterization of additional virulence factors and vaccine targets. Although it is the most frequently isolated opportunist pyogen of the horse, S. zooepidemicus has been the subject of few contemporary research studies. Variation in the protectively immunogenic SzP proteins has, however, been well characterized. Given its opportunist behavior, studies are urgently needed on regulation of virulence factors such as capsule and proteases. Likewise, information is also very limited on virulence factors and associated gene regulation of S. dysgalactiae subspecies equisimilis. It has recently been shown that equine isolates of Streptococcus pneumoniae are clonal, a feature shared with S. equi. All equine isolates express capsule Type III, are genetically similar, and have deletions in the genes for autolysin and pneumolysin. In summary, the evolving picture of the interaction of the equine pathogenic streptococci and their host is that of multiple virulence factors active at different stages of pathogenesis. The inherent complexity of this interaction suggests that discovery of effective combinations of immunogens from potential targets identified in genomic sequence will be laborious. 相似文献
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Antigenic classification of group C animal streptococci 总被引：8，自引：0，他引：8
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近几年业 ,宁夏银川郊区、平罗、吴忠等地的羊群羔羊发生一种以急性纤维素性肺炎为主要特征的疾病 ,经诊断为羔羊肺炎链球菌感染 ,现报告如下。1 流行病学调查宁夏银川郊区、平罗、吴忠等地三羊场共养母羊 31 5只 ,2 0 0 1年产羔 2 6 0只左右 ,由于各种原因死亡 6 9只 ,其中 2 9只死前均表现典型肺炎症状及纤维素性肺炎病变 ,占死亡羔羊总数的 4 2 %。发病羔羊均为 7～ 50日龄 ,其中以 1 0～ 30日龄羔羊最多 ,成年羊不发病。发病羔羊多数体质瘦弱 ,母羊多为小尾寒羊 ,产多胎 ,母乳不充足。羔羊发病死亡多集中在产羔中、后期 ,此时气温回升 … 相似文献
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C L?mmler C Frede H Blobel 《Comparative immunology, microbiology and infectious diseases》1988,11(2):115-119
Streptococci of serological groups A, B, C, G and L were examined for interactions with human colostral IgA. Of 28 A-streptococcal cultures, 12 bound IgA with a mean of 38.7%. The other streptococci had little or no IgA-binding activities. Of the 12 IgA-binding A-streptococcal cultures, 8 contained the M-protein M 4 and 2 the M-protein M 60. The specific binding sites for IgA were heat-sensitive (60 min, 80 degrees C) and susceptible to trypsin and pronase. 相似文献
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Serologic group relationship of P and U streptococci 总被引：1，自引：0，他引：1