共查询到20条相似文献，搜索用时 31 毫秒
1.
Karen M Vernau Anna Osofsky Richard A LeCouteur 《Veterinary Clinics of North America: Exotic Animal Practice》2007,10(3):731-58, v
Completion of a thorough neurological examination of a rabbit is essential for clinicians to determine the location of a neurological problem. Determination of the location of a lesion (whether solitary or multifocal/diffuse) enables a clinician to list the most likely causes of the problem. This article presents the neurological examination of the rabbit, followed by a practical guide to lesion localization in this species. 相似文献
2.
SUMMARY This paper describes a case of a congenital vascular malformation in the skin of a colt. The lesion arose at the coronary border of the right hind leg. The microscopic structure of a biopsy suggested that the lesion, consisting of multiple foci of closely-packed convoluted small vessels in the dermis, represented a marked exaggeration of glomi which normally occur in considerable numbers in this region of the skin. On the basis of the clinical, macroscopic and histological findings, this lesion was considered to be an hamartoma, rather than a true tumour, and was therefore termed a congenital vascular naevus. The foal is remaining under observation to determine the eventual outcome of the lesion. 相似文献
3.
An intra-abdominal testicular tumour was diagnosed in a 10-year-old, male, cryptorchid golden retriever. Upon surgical removal, torsion of the testis was found. The histopathological diagnosis was seminoma. The ultrasound examination in this case revealed a parenchymal mass lesion. An ultrasound examination is a useful supplemental diagnostic tool for differentiation of abdominal mass lesions. 相似文献
4.
E. Ferreira A. C. Bertagnolli M. F. Cavalcanti F. C. Schmitt G. D. Cassali 《Veterinary and comparative oncology》2009,7(4):230-235
Tumour size is considered one of the most important determinants of clinical staging in cancer patients. The aim of this study was to assess the value of tumour size as an indicator of the differentiation of mammary neoplasias in female dogs. The tumour, nodes metastates (TNM) system, based on primary lesion size, the extent of its dissemination to regional lymph nodes and the presence or absence of distant metastases, was applied to 120 female dogs diagnosed with mammary neoplasias. Paraffin blocks from 38 cases were selected and studied by immunohistochemical staining for prognostic and predictive markers of breast cancer. The Kaplan–Meier survival curve was estimated for 110 female dogs. Larger tumours (T3) were mostly malignant and showed lower expression of progesterone receptor and higher expression of cellular proliferation markers. Global survival time was shorter in female dogs with large tumour masses. This study highlights the importance of tumour size as a prognostic indicator of mammary neoplasias in female dogs. 相似文献
5.
An 18-month-old Friesian heifer had several unusual, raised, black, cutaneous plaques, some of which were up to 20 cm in diameter, on its head and neck, limbs, thorax and perineum. There was also generalised lymphadenopathy. A clinical diagnosis of lymphosarcoma (sporadic bovine leukosis) was derived from a fine needle aspiration of a skin lesion. Post mortem and histological examinations confirmed a multicentric lymphosarcoma with widespread infiltration into many of the tissues recognised as predilection sites for this type of tumour. However, in the authors' experience, the presence of tumour masses in the trachea and the right mainstem bronchus was atypical. 相似文献
6.
芩连液与白虎汤对脂多糖致家兔肝损伤的疗效比较 总被引：1，自引：1，他引：0
为比较自拟方芩连液和白虎汤对高热病症的治疗效果,通过静脉注射脂多糖(LPS)复制了家兔高热病症,并在两种药物治疗前后分别进行了肝脏组织病理观察与血清生化指标分析。结果显示,15 μg/kg LPS能致家兔肝脏组织产生明显病理损伤,血清丙氨酸氨基转移酶(ALT)、天冬氨酸氨基转移酶(AST)和尿素(Urea)含量上升,而总胆固醇(TC)含量下降,经白虎汤和芩连液治疗后肝脏组织病理损伤显著减轻,4项血清生化指标向正常水平恢复。结果表明,白虎汤和芩连液对LPS引起的肝损伤都具有显著的治愈效果,且两种组方的疗效各有优势。 相似文献
7.
A domestic shorthaired cat had a firm, non-painful swelling of the left antebrachium. Radiographs showed an expansile, multiloculated lesion in the radius. The mass gradually enlarged over the following four and a half months and the animal became completely lame. The histological diagnosis was giant cell tumour of bone; this is a rare neoplasm of bone in veterinary patients. Giant cell tumour of bone should be considered in the differential diagnosis of bone lesions having an expansile, multiloculated radiographic appearance. 相似文献
8.
S E Hajos E Alvarez S Pierangeli R A Margni C D Pasqualini 《Veterinary immunology and immunopathology》1985,8(1-2):157-169
A soluble tumour-associated antigen was prepared by homogenizing AKR lymphoma cells (L15) followed by treatment with acetone and glycine-HCl buffer pH 3. It was analyzed by immunoelectrophoresis, rocket electrophoresis in the presence of Concanavalin A and SDS-PAGE. It showed rapid electrophoretic mobility, and the major component had an estimated molecular weight of 70,000 daltons. The molecular composition of the antigen included a glycoprotein. Specific antibodies against this antigen were demonstrated in BALB/c mice in which the AKR lymphoma was conditioned to grow by introducing the L15 cells into a subcutaneously implanted glass cylinder. In this model antibodies were found in both tumour-bearing (progressor) and tumour-rejecting (regressor) animals. In vivo experiments showed that pretreatment of BALB/c mice with L15 acellular extracts, 10 days before tumour challenge, led to a significant increase in allogeneic tumour growth. A rabbit anti-tumour extract serum was prepared and was rendered tumour -specific by exhaustive absorption with normal AKR serum and tissues. It shared the same epitopic specificity with tumour progressor or regressor mouse sera since indirect immunofluorescence using L15 cells could be reciprocally inhibited. 相似文献
9.
Six entire male rabbits, between four and eight years old, were presented with a fluctuant scrotal and/or inguinal swelling resulting from inguinal herniation of the urinary bladder. Concurrent problems included urinary sediment (two rabbits), multiple uroliths (one rabbit) and testicular tumour (one rabbit). All rabbits underwent herniorrhaphy surgery. There was a successful outcome in four of the six cases. 相似文献
10.
G. C. Macpherson B. J. Chadwick P. D. Robbins 《The Journal of small animal practice》1993,34(5):242-246
A dog was presented with signs of subacute, progressive myelopathy. A tentative diagnosis of a diffuse intramedullary spinal cord mass was made using contrast radiography (myelography). At autopsy a solitary, large bronchoalveolar carcinoma was detected in a lung lobe. Histological examination of the cranial thoracic spinal cord revealed a tumour which was similar, but not identical, to the lung tumour. Immunohistochemistry helped to confirm that the spinal lesion was a metastasis of the lung tumour. 相似文献
11.
A case of a feline Merkel cell tumour is described. An 8-year-old, female cat developed a round, alopecic, reddish mass on the nose. Wide excisional surgery was performed with cartilage resection. Histologically the mass was composed of solid islands of mostly basophilic densely packed cells with a scant cytoplasm, which was suggestive of a neuroendocrine origin. Results of immunohistochemical studies using antibodies against neurone-specific enolase, chromogranin, synaptophysin and pan-cytokeratin allowed classification of the lesion as a Merkel cell tumour. Ultrastructurally, dense core granules were identified in the cytoplasm. In a 2-year follow-up no relapses or metastases were observed. The clinical course recorded is in contrast with the malignant nature of a Merkel cell tumour recently described in a cat and of the human Merkel cell tumour, but is similar to the course of the canine Merkel cell tumour which is often benign. Early diagnosis along with the use of wide surgical excision might be considered an important factor in preventing relapse of this tumour. 相似文献
12.
J. A. SPENCE P. E. HOLT† P. D. SAYER† D. ROTTCHER† J. E. COOPER 《The Journal of small animal practice》1978,19(1-12):175-184
This report presents a case of metastasising transmissible venereal tumour (TVT) with lesions of the penis, lip, spleen and pituitary. The clinical picture is outlined and the associated diagnostic radiographic procedures used to reach a final diagnosis of a space–occupying lesion in the region of the pituitary are described. A definitive diagnosis of a metastasizing TVT was reached by histopathological examination and it is concluded that the pituitary and spleen metastases are examples of the systemic dissemination of the original penile tumour whilst the lip lesion probably arose by direct contact. 相似文献
13.
Kashiwagi E Masuno K Fujisawa K Matsushima S Torii M Takasu N 《Journal of toxicologic pathology》2012,25(1):51-53
Goniodysgenesis, malformation of the filtration angle, was observed in a New Zealand white rabbit supplied with 100 g/day rabbit chow containing 0.2% cholesterol for 10 months. Histopathology revealed cupping of the optic disc, atrophy of the retina and hyalinization of the ciliary body in the bilateral eyeballs. These findings corresponded with histopathological features caused by glaucoma. On the basis of these findings, we diagnosed this lesion as glaucoma, and classified it as primary glaucoma because of the presence of developmental defects of the filtration angle. In this case, hypercholesterolemia-induced changes, such as aggregation of lipid-laden macrophages and cholesterin clefts in the sclera or choroid, might cause deterioration of the lesions in glaucoma. 相似文献
14.
Stadler S Kainzbauer C Haralambus R Brehm W Hainisch E Brandt S 《The Veterinary record》2011,168(7):187
Based on the anecdotally reported eradication of a sarcoid using aciclovir cream, the curative potential of this ointment was investigated in 22 sarcoid-affected horses referred to the Equine Clinic Tillysburg, Austria, between 2006 and 2009. Sarcoid disease was diagnosed by clinical examination and bovine papillomavirus types 1 and 2 from intact skin and tumour tissue. As nine horses had more than one lesion, a total of 47 sarcoids were treated by daily topical application of aciclovir 5 per cent cream for a period of two to six months; in four horses, surgical tumour ablation was performed before treatment. Disease parameters, including the tumour type, number, location and size, were recorded before and after aciclovir therapy. All 47 (100 per cent) of the sarcoids responded to treatment, with complete tumour regression observed for 32 (68 per cent) lesions and no recurrences reported thus far. Incomplete resolution was observed for 15 (32 per cent) lesions, probably due to their thickness. Aciclovir is proposed to be routinely used for the treatment of mild-type sarcoids and as an adjuvant therapeutic agent in combination with surgery. 相似文献
15.
An ulcerated lesion resembling a tumour in the lesser curvature of the stomach of a 3-year-old male Dobermann pinscher was found to be caused by Cryptococcus neoformans. The dog had been vomiting for two months and had slight leucocytosis and anaemia. Biopsies of the ulcerated lesion revealed granulomatous inflammation and many cryptococci, which were particularly prominent in PAS and mucicarmine stained sections. No other lesions were found at necropsy. 相似文献
16.
Stephen D. White Terry Campbell Ava Logan Anna Meredith Patricia Schultheiss Tom Van Winkle Peter F. Moore Diane K. Naydan & Francine Mallon 《Veterinary dermatology》2000,11(1):61-67
Three domestic rabbits ( Oryctolagus cuniculus ) with cutaneous lymphoma are described. Two rabbits were young (7 weeks and 1 years) and were euthanized within 1 week of showing clinical signs. Lymphoma was found in the skin and internal organs. The third rabbit was 9.5 years of age, and lived for more than 1 year after diagnosis. No response was seen to either 2 months of alpha-interferon administration or a 2.5-week course of isotretinoin treatment. After 1 year the rabbit died suddenly; the owner refused necropsy. Immunologic stains of the tumour in all three rabbits showed T cells to be the lymphoma cell type. 相似文献
17.
Saito K Tagawa M Mimura M Hasegawa A 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2005,67(1):79-81
Rabbit syphilis was experimentally transmitted from clinical cases to healthy rabbits. The purpose was to evaluate changes in RPR titers during the course of infection and to detect the pathogenic organism. Two of three littermate rabbits were inoculated topically. One rabbit became symptomatic, with typical clinical signs on its genitalia about 8 weeks after inoculation and a marked rise in RPR titers, another remained asymptomatic with a moderate rise in titers, and the control rabbit remained negative. These results supported the specific relationship between clinical signs and RPR titers. Histopathological examination of the skin lesion from the symptomatic rabbit revealed spirochetes. 相似文献
18.
Sergio Ródenas Marti Pumarola Lluís Gaitero Àngels Zamora Sònia Añor 《Veterinary journal (London, England : 1997)》2011,187(1):85-91
Magnetic resonance (MR) images of 40 dogs with histologically confirmed primary and secondary intracranial tumours were reviewed. Forty-one tumours were diagnosed by means of MR imaging (MRI). MRI findings allowed diagnosis of a neoplastic lesion in 37/41 cases. Based on MRI features, differentiation between neoplastic and non-neoplastic lesions was possible in 24/27 (89%) primary brain tumours and in 13/14 (92%) secondary brain tumours. Diagnosis of tumour type based on MRI features was correct in 19/27 (70%) primary tumours and in 13/14 secondary tumours. The results of this study show that MRI is a good diagnostic imaging modality to detect neoplastic lesions and to diagnose tumour type in dogs. However, as some neoplasms show equivocal MRI features the technique has limitations in the detection of some intracranial tumours and in predicting tumour type. 相似文献
19.
Wagner F Beinecke A Fehr M Brunkhorst N Mischke R Gruber AD 《The Journal of small animal practice》2005,46(8):393-397
A five-year-old, castrated, male chinchilla rabbit was presented for evaluation of recurrent bilateral exophthalmos. Besides a transient and stress-related exophthalmos with protrusion of both third eyelids, the ophthalmological examination was unremarkable. Plain radiography of the thorax revealed a large precardial mass of soft tissue density. Cytological preparations from the thoracic mass were dominated by small, mature lymphocytes with approximately 10 to 20 per cent lymphoblasts. Computed tomography of the head showed a symmetrical laterodorsal deviation of both eyes without evidence of retrobulbar masses. On necropsy a large cystic mass was present in the cranial thorax associated with severe hydrothorax, hydropericardium and ascites. Histology identified the precardial mass as thymic carcinoma with metastases in the kidneys. This case illustrates the difficulty of diagnosing thymic tumours based on cytological or histological features of the primary tumour alone. To the authors' knowledge, this is the first case of recurrent bilateral exophthalmos associated with a metastatic thymic carcinoma in a pet rabbit. 相似文献