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兔痒螨(Psoro ptes cuniculi)寄生于兔外耳道引起外耳道炎,并形成厚的痂皮,严重时可蔓延筛骨及脑部,以致引起癫娴.过去,我们常以有机磷、有机氯和菊酯类杀虫剂驱治,虽经多次涂擦,治愈效果不太理想。为了寻求更为有效的治疗方法,我们采用灭虫丁注射液对兔痒螨病进行了治疗效果观察,取得了 相似文献
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兔螨病是一种常见而难以根除的外寄生虫病,病程可长达几个月.患兔少食、不安,逐渐消瘦,衰竭而死,且皮毛受损,严重影响养兔业的发展.兔螨病按侵袭部位分为耳癣和身癣.耳癣为痒螨科兔痒螨引起,主要侵害外耳道;身癣为疥螨科兔疥螨和背肛螨引起.前者主要侵害四肢,甚而侵害头部、嘴等,后者多侵害耳廓、嘴、鼻,亦可蔓延到四肢.尤以兔疥螨最为普遍且危害严重.治疗本病的方法虽多,但疗效均不理想.有的药品,如敌百虫等还易引起中毒.1987年我们用750ppm螨净及750ppm塔克敌克水溶液浸泡患部治疗兔螨病,方法简便,效果良好.但对结痂厚者,治疗时需要除 相似文献
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1病因及特点仔幼兔在一般条件下不易患螨病,全国测算有95%以上的养兔场户,在仔、幼兔群中不患螨病。如果有少数场户的仔、幼兔患螨病,甚至患了严重的螨病,均有下列致病因素:①饲养室极度潮湿,达85%左右;②兔笼及笼底板堆积兔粪、污物;③产仔箱、垫草潮湿和污染;④产箱内的垫物潮湿、污染并长期、反复使用;⑤哺乳母兔大多数患有螨病,场内大多数兔也患有螨病,等等。由于以上原因的严重影响,仔幼兔的螨病极易发生,甚至感染全群。2症状螨病按发病部位,分耳螨、足螨、身螨。仔、幼兔患螨病大多为身螨,因为产仔箱感染致病为主要源。本病初期在患部… 相似文献
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Stipkovits L Ripley PH Tenk M Glávits R Molnár T Fodor L 《Research in veterinary science》2005,78(3):207-215
Mycoplasma bovis infection was experimentally induced in groups of six young calves. A further group was uninfected and served as a control. Ten days after infection, medication with either enrofloxacin (Baytril, Bayer) or valnemulin (Econor, Novartis) was instituted via the milk replacer for a further 10 days, after which all calves were killed. Infection resulted in depression, pyrexia, inappetance and prominent respiratory signs. Arthritis occurred in two animals and two (unmedicated) animals died. At post-mortem examination extensive lesions were present in the lungs and M. bovis was re-isolated from infected unmedicated calves' lungs. Medication with either enrofloxacin or valnemulin resulted in a rapid diminution of clinical signs, restoration of appetite and reversal of weight loss. Isolation of Pasteurella multocida from the calves' lungs was suppressed by both medicaments. Valnemulin resulted in a more rapid reduction of clinical scores and eliminated M. bovis from the lungs more effectively than enrofloxacin. 相似文献
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Fischer JR Harkin KR Freeman LC 《Veterinary therapeutics : research in applied veterinary medicine》2002,3(4):465-473
Randomized crossover studies were performed to determine the effect of coadministration of d-alpha-tocopheryl polyethylene glycol 1,000 succinate (vitamin E TPGS) on the oral bioavailability of cyclosporine A (CsA) formulated as either Sandimmune (Novartis Pharmaceuticals) or Neoral (Novartis Pharmaceuticals). Healthy dogs were given a single oral dose of each cyclosporine formulation with and without vitamin E TPGS. Blood samples were collected from each dog before and at various intervals for 24 hours after drug administration. Whole-blood CsA concentrations were determined by high-pressure liquid chromatography. Noncompartmental pharmacokinetic analysis showed that coadministration of vitamin E TPGS increased the oral bioavailability of Sandimmune. The bioavailability of Neoral was greater than that of cyclosporine. Concurrent administration of vitamin E TPGS had no consistent effect on the bioavailability of Neoral. 相似文献
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用兔出血症毒(RHDV)和巴氏杆菌研制成蜂胶佐剂灭活苗,用1.0mL免疫试验兔,免疫后第5天,对RHDV保护率达100%;免疫后第7天对巴氏杆菌的保护率为72.5%,通过HI法监测兔病毒性出血症抗体水平,结果表明:蜂胶苗产生抗体时间较早,第7天后HI效价25.0,第20天效价显著上升达29.25以上,第30天达到最高峰,可达211.0,60~120 d均可维持在27.0~25.5水平,到第180天时抗体水平面略有下降为25.25,蜂胶苗分别在免疫后4个月、6个月用兔出血症强毒攻击均产生100%保护,在6个月用2个MLD的兔巴氏杆菌攻击保护率可达70%以上,二联苗4~8℃条件下保存期暂定为1年,25℃条件下暂定为半年。 相似文献
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《Journal of Exotic Pet Medicine》2014,23(4):397-402
A 6-year-old male rabbit (Oryctolagus cuniculus) presented with upper respiratory disease that was nonresponsive to antibiotic therapy. Computed tomography revealed a severe space-occupying lesion of the right nasal cavity, deviation of the nasal septum to the left, and narrowing of the left nasal cavity. An exploratory rhinostomy was performed for the purposes of diagnostic sample collection and to improve airflow as clinical signs of dyspnea were becoming more pronounced. The histopathologic disease diagnosis from the biopsy samples was nasal mucosal adenocarcinoma. Palliative rhinostomy provided only temporary improvement in airflow, and the patient was euthanized 3 days later. On necropsy, neoplasia was found to extend into the rhinopharynx. This is the first reported case of nasal mucosal adenocarcinoma in rabbits. This important differential diagnosis should be considered for any rabbit with clinical signs of upper respiratory disease that is nonresponsive to medical therapy. 相似文献
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不同剂量中草药与西药防治兔球虫病的比较试验 总被引：1，自引：0，他引：1
用不同剂量的中草药和地克珠利对球虫病幼兔进行防治对比试验,结果显示：兔粪便中球虫卵囊的减卵率随中草药剂量的增加而增加,以1．5％中草药剂量（第3组）防治效果最好,平均减卵率为93．60％,高出0．5％中草药剂量组（第1组）8．67个百分点。高出1．0％中草药剂量组（第2组）2．45个百分点,高出地克珠利组（第5组）7．89个百分点。而不用抗球虫药的对照组（第4组）球虫卵囊比试验前增加了269．86％;平均增重,第3组为1．48±0．09kg,效果最好,比第1组（1．32±0．15kg）提高12．12％,比第2组（1．40±0．14kg）提高5．56％,比第5组（1．36±0．12kg）提高8．89％,比第4组（0．75±0．08kg）提高97．33％;料重比,第3组（2．34：1）较第5组（3．16：1）下降34．5％。试验结果表明,以1．5％中草药剂量治疗兔球虫病效果最好,不但可以治疗球虫病。而且可以提高兔的生长性能和成活率。 相似文献
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猪伪狂犬病不同佐剂灭活疫苗对兔免疫原性初探 总被引：1，自引：1，他引：0
采用分离鉴定的猪伪狂犬病毒（HB—J株）以4种佐剂研制成4批灭活疫苗,以研究其对兔的免疫原性。疫苗分别免疫PRV抗体阴性兔后,用乳胶凝集试验法（LAT）和中和试验法（SNT）对试验兔进行血清抗体检测;于免疫后21、28d对试验兔分别进行攻毒,观察兔保护情况。试验结果表明,兔对不同佐剂的猪伪狂犬病疫苗均产生良好的免疫应答反应,且当兔免疫后血清凝集价≥1：32或血清抗体中和指数≥1479或中和价≥1：16时,可以抵抗10LD50剂量强毒的攻击;当兔免疫后血清凝集价≥1：64或血清抗体中和指数≥2187或中和价≥1：32时,可以抵抗100LD50剂量强毒的攻击;4种佐剂灭活疫苗均具有良好的免疫效果。 相似文献
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Comparative efficacies of oral ketoconazole and terbinafine for reducing Malassezia population sizes on the skin of Basset Hounds 总被引：1，自引：0，他引：1
Guillot J Bensignor E Jankowski F Seewald W Chermette R Steffan J 《Veterinary dermatology》2003,14(3):153-157
The objective of this study was to compare the efficacy of oral ketoconazole and terbinafine for reducing population sizes of Malassezia yeasts on canine skin. Twenty-one Basset Hounds were randomised in three groups of seven according to Malassezia populations. Dogs in the first group were treated by oral administration of ketoconazole (Ketofungol) 200 mg, Janssen-Cilag) at 10 mg x kg-1, every 24 h with food, for 3 weeks. Dogs in the second group were treated by oral administration of terbinafine (Lamisil) 250 mg, Novartis) at 30 mg x kg-1, every 24 h with food, for 3 weeks. The seven remaining dogs were used as controls. Malassezia population sizes were assessed by use of contact plates on four cutaneous sites at days 7, 14 and 21. Both ketoconazole and terbinafine were effective in reducing the baseline levels of Malassezia organisms with no significant difference between the two drugs. In further studies, oral terbinafine should be evaluated for the management of canine cases of Malassezia dermatitis. 相似文献