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1.
Salgüero R Langley-Hobbs S Warland J Brearley M 《Journal of Feline Medicine and Surgery》2012,14(6):432-435
A 14-year-old male neutered Burmese cat presented for investigation of right fore limb lameness that was non-responsive to anti-inflammatory drugs and opioids. Thoracic radiography showed multiple pulmonary soft tissue nodules and a larger cavitated mass. Right elbow radiographs revealed marked peri-articular proliferation of new bone and periosteal reaction primarily affecting the ulna. Histopathological examination of an incisional biopsy of the right ulna revealed neoplastic proliferation of epithelial cells; this was confirmed as a poorly differentiated carcinoma with immunohistochemistry. Amputation of the right fore limb was performed at the owner's request. After surgery, radiographs of the limb showed progression of bone proliferation. Repeat pathological analysis confirmed a metastatic carcinoma. The cat deteriorated 3 days after surgery and was euthanased a week later as a result of severe respiratory distress. This case represents an unusual case of metastasis of a suspected primary lung tumour to the ulna in a Burmese cat. 相似文献
2.
Lee JH Lee JH Yoon HY Kim NH Sur JH Jeong SW 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2012,74(5):667-672
A six-year-old intact female Maltese dog weighing 3.8 kg presented with a history of mild lameness and swelling on both forelimbs. Radiographic and computed tomographic views revealed an extensive periosteal reaction in all four limbs and a large round mass on the right middle lung lobe. A total lobectomy was performed and pulmonary adenosquamous carcinoma was histologically confirmed. A diagnosis of hypertrophic osteopathy (HO) secondary to a lung tumor was made. Periosteal proliferation decreased significantly after surgery; however, there was evidence of dyspnea, mass recurrence, and periosteal reaction three months post-operatively. This is the first case report of pulmonary adenosquamous carcinoma with HO in a dog in which we describe clinical, imaging, surgical, and histological findings. 相似文献
3.
Hypertrophic osteopathy (HO) is a rare condition in the horse characterised by symmetrical proliferation of connective tissue and subperiosteal bone, along the diaphyses of limb bones. In this case, a 10‐year‐old Irish Draught cross Thoroughbred mare was presented for investigation of weight loss, lethargy and firm swelling of all 4 distal limbs. Radiographs of the distal limbs revealed palisade‐like periosteal new bone formation perpendicular to the cortex of the distal third metacarpal and metatarsal bones, proximal (P1) and mid (P2) phalanges. Rectal examination revealed a mass of approximately 20 x 30 cm in the right caudoventral abdomen. The mare was diagnosed with HO due to a granulosa thecal cell (GTC) tumour. The GTC tumour was removed and the diagnosis confirmed on histological examination. Clinical examination and radiographs of the distal limbs after surgery demonstrated reduction in size of the limb swellings and new bone formation. To the authors' knowledge this is the first report of HO due to a GTC tumour in a mare. 相似文献
4.
Histoplasma capsulatum Osteomyelitis in the Cat 总被引：1，自引：0，他引：1
Alice M. Wolf DVM 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》1987,1(4):158-162
Seven cats with osseous lesions as the primary manifestation of disseminated Histoplasma capsulatum infection were evaluated. The major clinical signs in these cats were related to the bony lesions and included lameness, bone pain, and soft tissue swelling of limbs and joints. Other clinical and pathologic findings were similar to previously reported forms of disseminated histoplasmosis in the cat. The radiographic appearance of the lesions was predominantly osteolytic; periosteal and endosteal new bone production was present in some cases. Infection occurred primarily in bones of the appendicular skeleton with a predilection for sites below the elbow and stifle joints. 相似文献
5.
Maureen T. Long DVM Jonathan H. Foreman DVM MS Matthew A. Wallig DVM PHD Mark D. Chambers DVM MS John M. Losonsky DVM MS Michael C. Muhlbauer DVM 《Veterinary radiology & ultrasound》1993,34(4):289-294
A five year old American Saddlebred gelding was admitted to the University of Illinois Veterinary Medical Teaching Hospital with a history of multiple leg lameness, depression and intermittent fever for a duration of six months. Physical examination revealed the horse to be underweight, depressed and afebrile. No abnormalities were detected during auscultation of the heart and lungs. All limbs possessed multiple hard swellings of the distal long bones and digits. The horse walked with a stiff gait and was reluctant to trot. Nuclear scintigraphy of the distal limbs revealed multiple areas of focally increased uptake in all limbs. Radiographs of several sites on the distal limbs showed evidence of periosteal new bone production corresponding to the areas of abnormal uptake. The horse was euthanized and at necropsy chronic, multifocal, fibrous pericarditis and epicarditis were observed grossly. The left atrial myocardium contained areas of osseous metaplasia. Histological evaluation of the distal long bones revealed proliferative periosteal new bone formation consistent with a diagnosis of hypertrophic osteopathy. 相似文献
6.
A two‐year‐old Rottweiler presented for acute onset of a right hindlimb lameness 20 weeks after a cementless total hip replacement (THR) and 16 weeks after open reduction to address luxation of the THR. Radiographs revealed periosteal proliferation of the medial acetabulum and a stable implant. Synovial fluid cytology was consistent with inflammatory joint fluid. Treatment consisted of surgical debridement and intravenous and oral antibiotics. THR implants were not removed. Culture of tissue removed from the THR site yielded growth of Pseudomonas and Staphylococcus species. Lameness resolved 2 months after surgery. Twenty months after surgery, the dog was exercising normally with no clinical lameness and pelvic radiographs revealed no evidence of implant loosening and markedly decreased periosteal reaction. To the authors’ knowledge, this is the first report of an infected THR site successfully treated without prosthesis explantation in the dog. 相似文献
7.
J A Craig R G Helman M Walker 《Journal of the American Veterinary Medical Association》1985,186(10):1100-1101
An 8-year-old male Irish Setter was admitted because of nonweight bearing lameness of the left forelimb. Radiography failed to reveal any bony lesions of the forelimb; however, extensive periosteal new bone formation over most rib surfaces and an atypical cardiac silhouette suggestive of a mediastinal mass with pleural effusion were observed. New bone formation was seen on the ilium and a filling defect in the urethra, distal to the prostate, was apparent with contrast urethrocystography. Necropsy revealed scirrhous mesothelioma of the thorax and abdomen, multifocal periosteal exostoses, paraprostatic cyst, and benign prostatic cystic hyperplasia. Tumor cells were associated with the periosteal exostotic costal bone. The specific cause of the lameness was not determined. 相似文献
8.
J. C. Scott-Moncrieff G. S. Elliott A. Radoveky W. E. Blevins 《The Journal of small animal practice》1989,30(12):696-699
A 14-year-old domestic shorthaired cat was presented because of swelling of the digits and lameness. A solitary lung mass was observed on thoracic radiographs. Clinical and pathological evaluation confirmed a primary pulmonary squamous cell carcinoma metastatic to a single digit on each foot. Other metastatic lesions were present in the left popliteal lymph node and in the left iliac vein. 相似文献
9.
Navicular syndrome is a multifactorial disease process in horses with multiple structures in the foot contributing to lameness. Surgical debridement is a treatment option for lesions of the navicular bursa and deep digital flexor tendon. This retrospective case series describes the magnetic resonance imaging (MRI) appearance of the navicular bursa following bursoscopy. Seven horses (three being bilaterally affected) with forelimb lameness isolated to the foot, and pre- and post-operative MRI were included. All limbs had concurrent lesions associated with the deep digital flexor tendon, navicular bone, impar ligament, collateral sesamoidean ligament and/or distal interphalangeal joint. All bursae developed or had progression of proliferative bursal tissue following surgery. At recheck MRI, following rehabilitation protocols, almost all horses had improved to resolved lameness with relatively unchanged concurrent lesions despite the navicular bursa appearance worsening. Outcomes for return to work were poor with only two horses going back to the previous level of work. 相似文献
10.
Sonnenschein B Dickomeit MJ Bali MS 《Veterinary and comparative orthopaedics and traumatology》2012,25(5):418-420
An 18-year-old male, castrated Domestic Shorthaired cat was presented with the complaint of acute severe lameness of the left pelvic limb. There was no history of trauma, apart from a distal physeal left femoral fracture that had been repaired 17 years previously. Radiology revealed a displaced distal metaphyseal femoral fracture with marked areas of bone lysis and periosteal proliferations. A pathological fracture due to a bone neoplasia was suspected. An amputation with coxofemoral disarticulation was performed. Histopathology confirmed the tentative diagnosis of appendicular osteo-sarcoma. No postoperative complications were encountered and the cat made a full recovery. This case shows an unusual presentation of a late-onset fracture-associated feline osteosarcoma. 相似文献
11.
A 7-year-old, female, domestic medium-haired cat had a recurrent deep dermal mass in the interscapular region after initial surgical removal 3 months earlier. The cat had received a killed rabies vaccine and a five-in-one vaccine in the same area about 2 months prior to the first surgery. The relapsed mass was diagnosed as vaccine-associated sarcoma. The cat was euthanized 2 months later because of hind limb paralysis. At necropsy, multiple, poorly demarcated, nodular masses were seen in the muscles around the shoulders, neck, and thoracic vertebrae. Pulmonary metastasis and spinal epidural invasion at T1-T3 with regional cord compression and malacia were observed. Microscopically, the masses consisted of interwoven bundles of spindle cells with prominent multinucleated giant cell formation. The neoplastic cells stained strongly positive for myoglobin, and moderately but variably positive for vimentin, desmin, and alpha- smooth muscle actin. Phosphotungstic acid-hematoxylin staining revealed cytoplasmic striations in scattered tumor cells. The tumor was considered a vaccine-associated rhabdomyosarcoma. 相似文献
12.
Michael D. Lucroy DVM MS Jeffrey N. Peck DVM Clifford R. Berry DVM 《Veterinary radiology & ultrasound》2001,42(3):218-220
A 6-year-old neutered male Rottweiler was examined for a progressive right pelvic limb lameness. In radiographs of the right stifle, there was an osteolytic lesion with irregular new bone formation along the cranial aspect of the patella consistent with an aggressive bone lesion. In thoracic radiographs, there were multiple soft tissue nodular opacities throughout the lung fields, consistent with pulmonary metastases. Microscopically, fine needle aspirate samples from the right patella contained pleomorphic spindle cells with cytologic features of osteosarcoma. The presence of pulmonary metastases at the time of initial diagnosis in the dog described herein suggests that osteosarcoma of the patella has the potential for similar aggressive biologic behavior as that seen in dogs with appendicular osteosarcoma. 相似文献
13.
Rafał Sapierzyński 《Veterinary clinical pathology / American Society for Veterinary Clinical Pathology》2018,47(2):297-302
A 15‐year‐old spayed female domestic short‐haired cat with cutaneous/subcutaneous well‐circumscribed, alopecic mass approximately 25 × 30 mm in diameter, localized to the left shoulder region was brought to the veterinary surgery department. Despite the suggestive location and macroscopic appearance, feline injection‐site sarcoma was not suspected based on the cytologic examination of fine‐needle aspirates. The tumor was surgically resected, and tissue sections were evaluated microscopically. The tumor was found to be nonencapsulated with a distinct border between the neoplastic parenchyma and surrounding connective tissue. The neoplastic tissue consisted of 2 cell populations: elongated to spindle‐shaped cells arranged in bands and cords and malignant epithelial‐like cells. Both populations showed microscopic features of malignancy. Multinucleate giant cells with irregular cytoplasm were scattered among the neoplastic cells. The spindle‐shaped cells strongly expressed vimentin but did not express α‐smooth muscle actin (α‐SMA) or cytokeratin. Desmin was strongly expressed in about 0‐5% of cells. Epithelial‐like cells expressed cytokeratin, but not vimentin, desmin, or α‐SMA. Multinucleate giant cells expressed vimentin, but did not α‐SMA, desmin, or cytokeratin. Based on microscopic observations and IHC results, the final diagnosis was carcinosarcoma with histologic features compatible with feline injection‐site sarcoma, but without the clinical aggressiveness of this tumor. 相似文献
14.
Non-infective polyarthritis in the cat is classified into erosive (feline rheumatoid arthritis and feline periosteal proliferative polyarthritis) and non-erosive (feline systemic lupus erythematosus, feline idiopathic polyarthritis) forms. Criteria are used to identify each group. Clinically, all forms are similar. Affected cats are stiff, unwilling to move and may resent any form of handling. Joints are usually swollen and painful on manipulation. Some cases are pyrexic and inappetent. Radiography demonstrates destructive changes within joints in the erosive forms and also the periosteal new bone, characteristic of the periosteal proliferative form. Soft tissue thickening is also demonstrated. Tests for the autoantibodies rheumatoid factor and antinuclear antibody are important in the diagnosis of rheumatoid arthritis and systemic lupus erythematosus. Treatment is with anti-inflammatory and immunosuppressive agents (prednisolone, cytotoxic drugs). Cats with the rheumatoid and periosteal proliferative types do not recover but some manage to cope with the lameness. Cats with idiopathic polyarthritis can make a complete recovery although cases associated with myeloproliferative disease have a hopeless prognosis. 相似文献
15.
Andreasen CB Hedstrom OR Allison P 《Veterinary clinical pathology / American Society for Veterinary Clinical Pathology》1993,22(2):54-59
A 31-kg mediastinal mass from a 24-year-old horse is described. Cytologic imprints contained numerous spindle cells with indistinct cytoplasm and multiple foci of palisading nuclei. Histologic sections had these same characteristics and areas of central fibrillar material between palisading nuclei (Verocay bodies). Within histologic sections, spindle cell cytoplasm had positive immunoreactivity for vimentin and S-100, whereas immunoreactivity was not detected for desmin and cytokeratin. Cytologic, histologic, and immunochemical evaluation confirmed a diagnosis of solitary schwannoma. 相似文献
16.
Osteomyelitis caused by Cryptococcus neoformans was diagnosed in a three-year-old male Irish wolfhound. The case details and radiological findings of radiolucency and periosteal reaction of the left third metatarsal bone had lead to an initial diagnosis of a malignant bone tumour. Biopsy revealed a fungal granuloma and culture identified the causal organism. A four month course of ketaconazole was instigated and the lameness resolved. Twelve months after the end of treatment there was no recurrence of the problem. 相似文献
17.
S. Lynch Z. Halfacree I. Desmas S. D. Cahalan E. K. Keenihan C. R. Lamb 《The Journal of small animal practice》2013,54(10):555-558
An eight‐year‐old, neutered, male German short‐haired pointer was presented for a chronic cough and an intrathoracic mass. Computed tomography revealed a mass with low attenuation in the right caudal lung lobe that invaded the principal bronchi. The mass was removed by right caudal and accessory lung lobectomy. The histopathological diagnosis was pulmonary lipoma. The clinical signs resolved following surgery. There was no evidence of recurrence or de novo lesions on computed tomography performed 12 months post‐surgery. To the authors’ knowledge, this is the first report of a pulmonary lipoma in a dog. 相似文献
18.
Ralphs SC 《Journal of the American Animal Hospital Association》2005,41(1):78-80
A 9-month-old, castrated male, domestic shorthaired cat was presented for progressive right hind-limb lameness. A diagnosis of osteochondritis dissecans of the lateral femoral condyle was made based on radiographs and physical examination, and was confirmed by right lateral stifle arthrotomy. The cartilage flap was removed, and the underlying bone was curetted. Seven months later, the cat was sound on the right leg but developed a left hind-limb lameness. A similar lesion was found in the left leg and was treated identically. Fourteen months after presentation, the cat was sound on both hind limbs. 相似文献
19.
L. Klein M. Sacks A. E. Fürst F. Del Chicca P. Grest M. A. Jackson 《Equine Veterinary Education》2014,26(4):171-175
This case report describes the clinical findings, diagnosis and treatment of a 14‐year‐old Warmblood gelding with suture exostosis. The horse was referred to our clinic because of bilateral swelling in the region of the frontal and nasal bone junction and bilateral epiphora. Epiphora was the main concern for the owner and the reason for further investigation and treatment. Radiographic examination showed extensive bone proliferation on the dorsal frontal and nasal bones. Computed tomographic (CT) images further characterised the periosteal proliferation as new bone formation and localised it along the frontonasal and frontolacrimal suture lines. Computed tomographic images also showed pathological changes of both lacrimal ducts. A chronic fracture was suspected to be the cause of the periosteal proliferation, and surgical treatment using 2 small 2.4 Unilock plates was chosen to stabilise the suture between the frontal and nasal bones. The swelling decreased and the epiphora resolved by 6 months post operatively. A CT examination 2 years later showed complete healing. 相似文献
20.
A 14-year-old domestic shorthair cat presented with a 5-month history of urinary incontinence and inappro-priate elimination. Ultrasonography revealed a well-marginated, vascular mass of mixed echogenicity ex-tending from the dorsal wall of the urinary bladder into the lumen. Partial cystectomy was performed for re-moval of the urinary bladder mass; histopathological evaluation revealed a spindle cell neoplasm with a prominent palisading pattern. Histomorphologic features and immunohistochemical demonstration of vimentin, glial fibrillary acidic protein and S-100 protein, combined with negativity for smooth muscle actin and desmin were consistent with malignant peripheral nerve sheath tumour. This case report describes a novel location of malignant peripheral nerve sheath tumour; to the authors' knowledge, the bladder has not been described as a site of origin in the cat or any other domestic species. 相似文献