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1.
微生态制剂即一类以活菌为主的新型饲料添加剂,无毒、无害、无残留,是目前理想的抗生素替代品.在增强动物免疫力上作用很大。其活菌能在动物肠道内定植,维护肠道茵群平衡,并刺激肠粘膜免疫系统,引起体液免疫和细胞免疫应答,从而增强机体抗病力。  相似文献   

2.
活菌制剂在我国饲料工业中的应用   总被引:10,自引:0,他引:10  
活菌制剂在我国饲料工业中的应用广东省农科院畜牧研究所莫棣华,沈应然活菌制剂(Biogen)是近年来出现的一类新型饲料添加剂,是生物技术在动物营养保健方面具体应用的生物制剂。该产品以生物体或其相应的物质用于直接饲喂动物,具体参与动物胃肠道微生物的平衡,...  相似文献   

3.
活菌制剂在反刍家畜饲养中的应用   总被引:6,自引:0,他引:6  
李义海  谢宏 《饲料工业》1998,19(1):30-31
活菌制剂在反刍家畜饲养中的应用李义海谢宏活菌制剂(Biogen)是近年来出现的一类新型饲料添加剂,是生物技术在动物营养保健方面具体应用的生物制剂。该产品以生物体或其相应的物质直接饲喂动物,参与动物胃肠道微生物的平衡,对宿主产生生理效应,维持胃肠道的正...  相似文献   

4.
微生态制剂即一类以活菌为主的新型饲料添加剂,无毒、无害、无残留.是目前理想的抗生素替代品。在增强动物免疫力上作用很大。其活菌能在动物肠道内定植,维护肠道菌群平衡,并刺激肠粘膜免疫系统,引起体液免疫和细胞免疫应答。从而增强机体抗病力。  相似文献   

5.
<正>布鲁菌病是由布鲁菌引起的多种动物和人共患的传染病。在多种动物中,以牛、羊、猪的布鲁菌病的病例较常见,而且可将该病传染给人和其他动物。以生殖器官和胎膜出现炎症,引起妊娠动物流产、不育和其他组织出现局部炎症病灶。该病呈世界性分布,近年来,随着全国畜牧业的不断发展,为布鲁菌  相似文献   

6.
健康动物消化道的菌群屏障是保护动物免受病原微生物及内毒素侵害的重要保障。家兔肠道菌以厌氧菌为主,需氧菌为辅。肠道内容物中,需氧菌或兼性厌氧菌只占肠道菌群的5%以下,而占95%以上的都是厌氧菌。肠道菌群的结构正常及稳定,是家兔保持机体健康的重要因素;菌群紊乱会导致家兔机体生产性能低下,甚至暴发疾病。  相似文献   

7.
益生素就是可以直接饲喂动物的在动物消化道内起有益作用的微生物制剂,也可以叫做活菌制剂(Biogen)或生菌剂,它以活的形式在动物消化道中与病原菌进行竞争抑制、增强动物机体的免疫功能,并直接参与胃肠道微生物的平衡,加快达到胃肠道功能正常化的目的,  相似文献   

8.
活菌制剂的作用及研究应用   总被引:8,自引:0,他引:8  
活菌制剂的作用及研究应用北京农业大学动物科技学院安永义1.活菌制剂的作用1.1维持肠道菌群平衡,预防幼畜腹泻性疾病。正常情况下,动物胃肠道菌群保持着动态平衡,这表现在需氧菌和厌氧菌、有益菌和致病菌保持一定比例。比如,健康小猪,在小肠内需氧菌与厌氧菌之...  相似文献   

9.
布氏菌病是一种以动物为传染源的人畜共患的传染病。已知除牛、羊、猪、鹿、犬等家养动物对布氏菌易感外,还有许多种野生动物也可感染布氏菌。在我国,早有从鹿、犬、马、驼、黄鼠等动物体内分离到布氏菌  相似文献   

10.
二十一世纪的必然趋势──活菌制剂   总被引:4,自引:0,他引:4  
二十一世纪的必然趋势──活菌制剂北京欣谊畜牧有限公司刘春海,唐式法,戴晓曦动物在出生前处于无菌环境,出生后与母体及外界环境接触,一些微生物定居在动物体内。这些微生物中既有有益菌也有有害菌。正常情况下,有益菌与有害菌处于平衡状态,平衡状态的菌群能阻止病...  相似文献   

11.
To elucidate the effect of a large dose of di (2-ethylhexyl) phthalate (DEHP), a plasticizer and peroxisome proliferator-activated receptor-α (PPARα) agonist, on hepatic peroxisomes, we orally administered 1,000 mg/kg/day, once daily, to 3 male and 4 female cynomolgus monkeys for 28 days consecutively. Light-microscopic and electron microscopic examinations of the liver were carried out in conjunction with measurement of the hepatic fatty acid β-oxidation system (FAOS), carnitine acetyltransferase (CAT) and carnitine palmitoyltransferase (CPT) activities, which are peroxisomal and/or mitochondrial enzyme activities. Electron microscopically, enlargement of the mitochondria was observed with lamellar orientation of the cristae along the major axis. Although the number of peroxisomes showed a tendency to increase when compared with those in a biopsied specimen before treatment, no abnormality in morphology was observed. A slight increase in CPT activity was noted at termination. No changes were noted in hepatic FAOS or CAT activity. In conclusion, although repeated oral treatment of cynomolgus monkeys with a large dose of DEHP induced a subtle increase in the numbers of peroxisomes with slight enlargements of the mitochondria, this low-sensitivity response to peroxisome proliferators in cynomolgus monkeys was considered to be closer to the response in humans than that in rodents.  相似文献   

12.
The first case of Entamoeba of the 1-nucleate mature cyst group in birds is described. Trophozoites and cysts of Entamoeba have been found in ostriches (Struthio camelus) from farms located all over Spain. The cysts are large (13.47microm mean diameter); they possess one nucleus when mature, with a large endosome and peripheral chromatine arranged in small granules; chromatoid bodies, when present, are large and elongated. Trophozoites are large (19. 88microm mean diameter), with a clear differentiation between ecto- and endoplasm, this containing numerous vacuoles; the nucleus is large and diffuse. The characteristics of this amoeba resembles but do not completely fulfill those of E. suis and E. chattoni; also, these species are from mammals.  相似文献   

13.
Six mule deer (Odocoileus hemionus) with dermatomycosis are described. Trichophyton verrucosum was isolated from four. All infections were mild and were not debilitating. The lesions involved the legs in five animals and the face in two. This is the second report of ringworm in a wild ungulate in North America.  相似文献   

14.
15.
Roper (2020) conducted a critique of the Larson et al. (2019) study of the accuracy and confidence of data collected using systematic and random sampling designs.   Roper (2020) did not provide a data set but speculated that the Larson et al. (2019) conclusions likely reflected differences in the number of plants evaluated at each plot and the low number of independent observers rather than the sample design.  Our random sampling design employed multiple randomly located quadrat locations and measured multiple plants (> 5) that were averaged within the plot to represent plot characteristics.  Data collected in this fashion fulfilled assumptions intrinsic to and necessary for statistical analysis using plot data as observations.  Thus, the statistical observations reported in the original paper are valid.  相似文献   

16.
Three field trials were conducted over 12 months to assess the pathogenicity of Metarhizium anisopliae to parasitic stages of Rhipicephalus (Boophilus) microplus on dairy heifers under different environmental conditions. Two isolates were selected based on their high optimal growth temperature (30 degrees C), good spore production characteristics and ability to quickly kill adult engorged ticks in the laboratory. Spores were formulated in an oil emulsion and applied using a motor driven spray unit. Surface temperatures of selected animals were monitored, as were the ambient temperature and relative humidity. Unengorged ticks sampled from each animal immediately after treatment were incubated in the laboratory to assess the efficacy of the formulation and application. Egg production by engorged ticks collected in the first 3 days after treatment was monitored. Side counts of standard adult female ticks were conducted daily, before and after treatment to assess the performance of the fungus against all tick stages on the animals. In each trial the formulation rapidly caused 100% mortality in unengorged ticks that were removed from cattle and cultured in the laboratory. A significant reduction in egg production was recorded for engorged ticks collected in the 3 days post-treatment. However, there was little effect of the formulation on the survival of ticks on cattle, indicating that there is an interaction between the environment of the ticks on the cattle and the biopesticide, which reduces its efficacy against ticks.  相似文献   

17.
The clinical pathology and histopathology of two groups of Atlantic salmon with severe degenerative myopathy (pancreas disease) is described and compared with a third healthy group. One affected group was anorexic and had low plasma protein and albumin levels while the other was feeding and had normal levels. Both diseased groups had plasma and tissue vitamin E and selenium levels lower than the healthy group. Similarly, creatine kinase values were raised in affected groups. If representative of the syndrome as a whole, the results suggest that the myopathy of pancreas disease has a basis in a vitamin E-selenium deficiency, but whether primary or induced is not clear. The results also demonstrate that the myopathy and pancreatic atrophy do not inevitably lead to anorexia or any other clinically obvious sign of disease, despite both cardiac and oesophageal involvement.  相似文献   

18.
We previously reported that the enforced expression of exogenous whey acidic protein (WAP) significantly inhibited the proliferation of mouse mammary epithelial cells (HC11 and EpH4/H6 cells). This paper presents the first evidence that WAP also depresses the proliferation of mammary tumor cells from mouse (MMT cells) and human (MCF-7 cells). We established WAP-clonal MMT and MCF-7 cell lines, and confirmed the secretion of WAP from the WAP-clonal cells into culture medium. The enforced expression of WAP significantly inhibited the proliferation of MMT and MCF-7 cells in in vitro culture. FACScan analyses revealed that G0/G1 phase cell-cycle progression was disordered and elongated in the WAP-clonal MMT and MCF-7 cells compared to that of the control cells. The expression of cyclin D1 was significantly decreased in the WAP-clonal MMT and MCF-7 cells, suggesting that progression from the G1 to the S phase was delayed in the WAP-clonal cells. The present results indicate that WAP plays a negative regulatory role in the cell-cycle progression of mammary tumor cells via a paracrine mechanism.  相似文献   

19.
The time periods and the behavioural pattern of mink euthanized with carbon dioxide (CO2), 100% and 70%, carbon monoxide (CO), 4%, and nitrogen (N2), 100%, are described. The time between the placement of the animal in a glass box and the first symptoms of incoordination (phase I), the period of loss of consciousness (phase II), and, finally, the coma phase until cessation of respiration (phase III) using three groups each of 10 pastel male mink each were recorded. Phase I times ranged from 14 s for CO2, 31 s for N2, and 49 s for CO. In phase II, the difference was even more pronounced, being 5 s for CO2, 15 s for CO, and 45 s for N2. In phase III, the time was 58 s for N2, 134 s and 151 s for CO2 and CO respectively. Hence, the critical period from the time when the animals were placed in the glass box till unconsciousness occurred (phase I and II) was 19 s for CO2, 64 s for CO, and 76 s for N2. The total course of euthanasia was 153 s for CO2, 215 s for CO, and 134 s for N2. The following minimum times will be required before it can be judged to be safe to remove the animals: CO2 and N2: 5 min, and for CO: 6.5 min. In a supplementary experiment, involving a mixture of 70% CO2 and 30% atmospheric air, it was not possible within the allotted time to kill adult male mink.(ABSTRACT TRUNCATED AT 250 WORDS)  相似文献   

20.
The chemotactic activity of zymosan-activated serum (ZAS) and of two concentrations of recombinant human IL-8 (IL-8(25), 25 ng/ml; IL-8(50), 50 ng/ml) for ovine polymorphonuclear granulocytes (PMNs) was tested in a modified Boyden chamber. Thick cellulose acetate filters and the leading front method were used to quantify the movements of the cells. Both ZAS and IL-8(25) exerted a chemotactic effect on ovine PMNs (P < 0.01): IL-8(50) induced a more homogeneous response (P < 0.001). To verify the characteristics of the responsiveness to the chemokines after short-term (st) or long-term (lt) repeated samplings, chemotaxis was investigated 1 (T1st), 2 (T2st), 24 (T3st) and 48 h (T4st) after the basal sampling (T0st) and 15 days (T1lt) after the basal sampling (T0lt). No differences in chemotaxis were found in long-term repeated samplings. In contrast an increase in the responsiveness to IL-8(25) and to IL-8(50) (P < 0.05) was detected at T2st in comparison with T0st. Furthermore, the significance of the distance run by activated PMNs compared with the controls, increased from T0st to T2st, as a sign of a more homogeneous response to the chemokines. In the absence of evident changes in circulating leucocyte numbers and in serum cortisol concentrations, these findings could be interpreted as a consequence of a different expression of chemoattractant receptors on the membrane of PMNs collected at different times.  相似文献   

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