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1.
对大白母猪总产仔数,活产仔数,出生窝重,出生均重,断奶仔数,28日龄断奶均重,28日龄断奶窝重7个性状进行相关分析、偏相关分析和通径分析。结果表明各繁殖性状在表型值上都存在不同程度的相关。28日龄断奶仔数和28日龄断奶均重对28日龄断奶窝重影响最大,在此基础上建立估计28日龄断奶窝重的最优回归方程为:y^=-11.4892+2.4946X5+6.0171X6。  相似文献   

2.
试验选择50日龄断奶体重为16kg的仔猪120头,随机分成试验组和对照组。对照组饲喂玉米-豆粕型日粮,试验组饲喂非常规植物能量原料替代约50%玉米+生物能量专用酶(Bio-Energy-Specific Enzyme,BESE)0.12%。试验结果表明:试验组日增重较对照组提高2.27%(P0.05),料肉比降低2.43%(P0.05),试验组营养物质表观消化率均高于对照组,干物质提高1.99%(P0.05),能量提高0.98%(P0.05)、粗蛋白质提高4.24%(P0.05)、粗纤维提高13.01%(P0.05)。添加BESE可有效地提高日增重和饲料转化率。  相似文献   

3.
试验选择50日龄体重为16kg的杜×长×大三元杂交仔猪120头,随机分成试验组和对照组,每组设3个重复,每个重复20头,进行单因子试验。对照组饲喂玉米-豆粕型日粮,试验组饲喂非常规植物蛋白原料替代约50%豆粕+生物蛋白专用酶(Bio-Protein-Specific Enzyme,BPSE)0.12%。试验结果表明,试验组日增重较对照组提高1.73%(P0.05),料肉比较对照组低4.72%(P0.05),试验组营养物质表观消化率高于对照组,干物质提高1.06%(P0.05)、能量提高1.98%(P0.05)、粗蛋白质提高5.03%(P0.05)、粗纤维提高13.27%(P0.05)。添加BPSE可有效地提高日增重和饲料转化率。  相似文献   

4.
The virulence of a NAD-independent Actinobacillus pleuropneumoniae serotype 2 strain and NAD-dependent serotype 2, 3 and 9 strains was compared under experimental conditions. Hysterectomy-derived piglets were inoculated endobronchially with 50-500 cfu of these strains. All 23 piglets inoculated with the NAD-dependent strains developed acute disease within 12 hours post inoculation. Twenty-two of these piglets died within 24 hours after the first clinical signs. Three of nine piglets inoculated with the NAD-independent strain did not develop clinical disease. In the other six piglets, disease signs were similar as in the piglets inoculated with the NAD-dependent strains. No differences in clinical disease were observed between colostrum deprived piglets and piglets that obtained colostrum from a SPF sow.  相似文献   

5.
对松辽黑猪总产仔数(X1)、产活仔数(X2)、出生均重(X3)、出生窝重(X4)、20日龄窝重(X5)、断奶仔猪数(X6)、35日龄断奶窝重(y)7个繁殖性状进行了通径分析和回归分析。结果表明各个繁殖性状在表型值上都存在不同程度的相关,其中对断奶窝重影响最大的为断奶仔猪数,其次为20日龄窝重、产活仔数及总产仔数。建立最优回归方程为y=20.031—1.958x1O.405x5+8.201x6  相似文献   

6.
The objectives of this study were to determine the effects of oral Gln supplementation on growth performance, intestinal morphology, and expression of heat shock protein (Hsp) 70 in weaning piglets. A total of 65 piglets after weaning at 21 d of age (d 0) were used in this experiment. Five piglets were randomly selected and euthanized initially at d 0 to determine baseline values for the expression of Hsp70 in the small intestine. The remaining piglets were randomly assigned to 1 of 2 treatments and received 0 or 1 g of oral Gln/kg of BW every 12 h. After piglets were humanely killed at d 3, 7, and 14 postweaning, the duodenum, jejunum, and ileum of piglets were sampled to evaluate intestinal morphology and the expression and localization of Hsp70. The results indicated that oral Gln supplementation increased plasma concentrations of Gln compared with those in control piglets (P < 0.05). Average daily gain and ADFI were greater in piglets orally supplemented with Gln than in control piglets during the whole period (P < 0.05). The incidence of diarrhea in piglets orally supplemented with Gln was 24% less than (P = 0.064) that in control piglets at 8 to 14 d after weaning. The weights of the jejunum and ileum were greater in piglets orally supplemented with Gln compared with those of control piglets relative to BW on d 14 postweaning (P < 0.05). The villus height and the villus height:crypt depth ratio in the jejunum and the ileum were greater in piglets receiving oral Gln on d 14 postweaning (P < 0.05) than in control piglets. These results indicate that Gln supplementation can influence the intestinal morphology of weaned piglets. The expression of hsp70 mRNA and Hsp70 proteins in the duodenum and jejunum was greater in piglets supplemented with Gln than in control piglets (P < 0.05). However, Gln supplementation had no effect on the expression of hsp70 mRNA and Hsp70 proteins in the ileum. Moreover, the localization of Hsp70 in the cytoplasm indicated that Hsp70 has a cytoprotective role in epithelial cell function and structure. These results indicate that Gln supplementation may be beneficial for intestinal health and development and may thus mitigate diarrhea and improve growth performance. The protective mechanisms of Gln in the intestine may be associated with the increase in Hsp70 expression.  相似文献   

7.
OBJECTIVES: To determine the effects of oral administration of tilmicosin in piglets experimentally infected with Actinobacillus pleuropneumoniae. ANIMALS: Forty 3-week-old specific-pathogen free piglets. PROCEDURES: Piglets were assigned to 1 of 4 groups as follows: 1) uninfected sham-treated control piglets; 2) infected untreated piglets that were intratracheally inoculated with 10(7) CFUs of A pleuropneumoniae; 3) infected treated piglets that were intratracheally inoculated with A pleuropneumoniae and received tilmicosin in feed (400 ppm [microg/g]) for 7 days prior to inoculation; or 4) infected treated piglets that were intratracheally inoculated with A pleuropneumoniae and received chlortetracycline (CTC) in feed (1100 ppm [microg/gl) for 7 days prior to inoculation. Bronchoalveolar lavage (BAL) fluid and lung tissue specimens of piglets for each group were evaluated at 3 or 24 hours after inoculation. For each time point, 4 to 6 piglets/group were studied. RESULTS: Feeding of CTC and tilmicosin decreased bacterial load in lungs of infected piglets. Tilmicosin delivered in feed, but not CTC, enhanced apoptosis in porcine BAL fluid leukocytes. This was associated with a decrease in LTB4 concentrations in BAL fluid of tilmicosin-treated piglets, compared with untreated and CTC-treated piglets, and also with a significant decrease in the number of pulmonary lesions. Tilmicosin inhibited infection-induced increases in rectal temperatures, as measured in untreated and CTC-treated piglets. Pulmonary neutrophil infiltration and prostaglandin E2 concentrations in the BAL fluid were not significantly different among groups at any time. CONCLUSIONS AND CLINICAL RELEVANCE: Oral administration of tilmicosin to infected piglets induces apoptosis in BAL fluid leukocytes and decreases BAL fluid LTB4 concentrations and inflammatory lung lesions.  相似文献   

8.
为分析仔猪体内猪瘟母源抗体的衰减规律及母源抗体保护水平,测定了断奶时母猪和仔猪抗体水平,并监测仔猪母源抗体水平至81日龄;分别对12头81日龄仔猪(来自5头母猪)和25头35日龄仔猪(来自5头母猪)进行了攻毒试验,并用RT—nPCR进行了跟踪检测,对7头攻毒耐过猪用兔体中和法测定了中和效价。结果表明,母猪抗体水平不均衡会导致仔猪群体母源抗体水平不均衡;仔猪群体抗体到60日龄时仍然有67%(12/18)的个体用ELISA检测阻断率在50%以上:81日龄攻毒组有3头(3/12)耐过,35日龄攻毒组能全部耐过(25/25),但有2头(2/25)在攻毒27d后仍然呈PCR阳性,此时中和抗体水平从低于1:4到1:16不等,推测中和抗体水平1:8~1:16是母源抗体保护的临界线。  相似文献   

9.
For developing immunoglobulin yolk powder products to prevent and treat the diarrheal piglets, and appling the advanced technology of egg yolk antibody to the husbandry and aquaculture, two types of compound immunoglobulin yolk powder were used to prevent and treat the diarrhea piglets which were challenged with ETEC, PEDV and TGEV.The creep feed added with 0.4% typeⅠimmunoglobulin yolk powder was provided to experimental piglets.There was no death after challenging the piglets with ETEC or virus, only 5 minor diarrhea in piglets in the early infection.As feeding continuing, the 5 piglets diarrhea quickly brought under control, conversely, the piglets in negative control group were totally dead.The immunoglobulin yolk powder type Ⅱ mixed with GNS at the rate of 1∶3 was used to cure the diarrhea piglets, 20 mL per piglet and 2 times a day.After curing for 3 days, the diarrhea was greatly improved, for 5 days the piglets diarrhea was basic recovery, and the survival rate could reach 84% to 88%.Dectected the infected of surviving piglets, compared to the drug treatment control group, prevention group had the lowest pathogen amounts, and the drug treatment control group had the most serious infected.  相似文献   

10.
A rotavirus isolated from a field outbreak of diarrhoea in artificially reared piglets was purified, filtered and administered orally to gnotobiotic and conventional piglets. Four successive passages of the virus in gnotobiotic piglets produced severe diarrhoea within 20 to 24 hours of administration. The diarrhoea lasted several days causing dehydration, emaciation, loss of body weight and some deaths. Virus was demonstrated in the faeces of the infected piglets by electron microscopy. Conventionally reared piglets developed little or no diarrhoea when given virus, whereas artificially reared piglets developed moderate to severe diarrhoea which lasted from 3 to 8 days with some deaths. No clinical disease was obvious in surviving piglets following challenge with the virus 10 or 17 days after initial infections.  相似文献   

11.
Previous studies showed that supplementation of sows' diets with L-carnitine increases body weights of their piglets at birth. This study was performed to investigate whether piglets of sows treated with L-carnitine differ in their growth potential from that of piglets of untreated control sows after weaning. It was also investigated whether supplementation of piglets' diets with L-carnitine improves their growth after weaning. In two trials, piglets of the first litters of primiparous sows (trial 1) and the second litters of the same sows (trial 2) were divided into four groups: group 1, piglets of control sows, fed a control diet; group 2, piglets of control sows fed a diet supplemented with 30 mg L-carnitine/kg; group 3, piglets of L-carnitine-treated sows, fed a control diet; group 4, piglets of L-carnitine-treated sows fed a diet supplemented with 30 mg L-carnitine/kg. Mean initial body weights of the piglets of the four groups were identical. They were 8.5 kg in trial 1 and 12.5 kg in trial 2. Diets were fed ad libitum over a period of 35 days. Piglets from sows treated with L-carnitine did not differ in body weight gains, feed intake and gain : feed ratio from those of control sows. In trial 1, piglets supplemented with L-carnitine had higher body weight gains (p < 0.005) and showed a tendency towards a higher gain : feed ratio (p = 0.09) than piglets fed the control diets. In trial 2, no significant difference in these parameters emerged between piglets fed the diet supplemented with L-carnitine and those fed the control diet. In conclusion, this study shows that dietary L-carnitine treatment of sows does not improve the growth potential of their piglets after weaning under the conditions of equal initial body weights. The study also shows that L-carnitine supplementation of their diets improves the growth performance in light piglets of primiparous sows.  相似文献   

12.
We investigated the effects of rice feeding on growth performance and protein (amino acids) metabolism of weanling piglets. In all, 16 weanling piglets with an average initial weight of 7.5 kg were divided into two groups. One group was fed a corn‐soybean meal‐based diet, and the other was fed a rice‐soybean meal diet, containing around 46% of corn or rice, respectively. A two‐week growth trial was conducted. The average daily gain (p = .025) and feed efficiency (p = .011) in rice‐fed piglets were significantly higher than those in corn‐fed piglets. Liver lysine‐ketoglutarate reductase activity tended to be lower (p = .073) in rice‐fed piglets than in corn‐fed piglets. Plasma urea nitrogen concentration in rice‐fed piglets was significantly lower than that in corn‐fed piglets. Plasma glucose and insulin concentrations were significantly higher in rice‐fed piglets than in corn‐fed piglets. Plasma‐free valine, isoleucine, and tryptophan concentrations were significantly higher in rice‐fed piglets than in corn‐fed piglets. In contrast, plasma histidine concentration was significantly lower in rice‐fed piglets than in corn‐fed piglets. Overall, these results show that rice feeding improves the growth performance and affects the protein (amino acids) metabolism in weanling piglets.  相似文献   

13.
The aim of the present study was to determine the effect of dietary lysozyme levels on growth performance, gut health and non‐specific immunity of weanling piglets. A total of 150 weanling piglets were allocated to six treatments. The piglets were fed the same basel diet supplemented with 0, 30, 60, 90 and 120 mg/kg lysozyme as well as antibiotics for 28 days. From day 14 to day 28 of dietary treatment, piglets fed 90 mg/kg lysozyme had greater average daily gain than piglets fed control diet. During the whole experimental period, piglets fed 120 mg/kg lysozyme tended to have greater average daily gain than piglets fed control diet. Compared with piglets fed control diet, piglets fed diets containing antibiotics and 90 mg/kg lysozyme had greater villus height to crypt depth ratio in duodenum and jejunum. Additionally, dietary supplementation of 60 and 90 mg/kg lysozyme as well as antibiotics enhanced the phagocytic activity of peritoneal macrophages in piglets. In conclusion, dietary lysozyme can accelerate the growth of weanling piglets by improving gut health and non‐specific immunity and supplementing 90 mg/kg lysozyme is as effective as antibiotics (20 mg/kg colistin sulphate + 50 mg/kg kitasamycin) in improving the growth performance of weanling piglets.  相似文献   

14.
Groups of newborn piglets were vaccinated orally with a modified live transmissible gastroenteritis (TGE) virus vaccine at 3 days and 13 days of age, and treated with the synthetic interferon (IFN) inducer polyinosinic:polycytidylic acid (poly ICLC) at 2, 3 or 4 days of age. Control groups consisted of piglets which were vaccinated but not treated with poly ICLC, as well as piglets which were treated with poly ICLC but not vaccinated. Significantly higher mean IFN titres were produced in response to induction at 3 or 4 days of age than at 2 days, and the mean IFN titre of the vaccinated piglets treated with poly ICLC at 3 days of age was significantly higher than in the unvaccinated piglets which were treated at the same time. The mean TGE virus neutralizing antibody titres in the vaccinated piglets which were treated with poly ICLC on the day before vaccination were significantly lower than the mean titres in the untreated vaccinated piglets 10 and 14 days after the first dose of vaccine. The mean titres in the vaccinated piglets which were treated with poly ICLC at 3 or 4 days of age did not differ significantly from those in the untreated vaccinated piglets. The piglets which were treated with poly ICLC on the day after vaccination developed severe diarrhoea which persisted for 5-7 days.  相似文献   

15.
Causes of preweaning mortality were examined on a large intensive piggery. Diagnosis was made using comprehensive clinical histories combined with post-mortem data. Two thousand four hundred and twenty-six piglets were born in 238 litters. Pre-parturient and parturient losses were 2.9% and 5.4% of the total numbers of piglets born. Birth to weaning mortality was 11.3%. Among piglets born alive, overlaying was the most frequent cause of death (2.1%), followed by deaths due to diarrhoea (1.7%), anaemia (1.2%), savaging (1.1%) and losses of small weak piglets (0.9%). Most deaths, including stillbirths, were associated with below average birth weight, and two-thirds of all deaths of liveborn pigs occurred within 4 days of birth. Increased litter size resulted in decreased birth weights, an increased percentage of stillborn piglets and mummified foetuses, but duration of parturition was not affected. Stillborn piglets were born late in the litter and after a longer interval between pigs born (interpig interval). Over 70% of deaths due to overlay were in previously healthy piglets, but some were associated with illness of the sow (18%) or both sow and piglet (3%). Savaging was confined mainly to first parity sows and was responsible for 20% of all deaths in these litters. Sixty-two per cent of all piglets with a birth weight of less than 800g were stillborn or died before weaning compared with 18.7% mortality for all piglets. Anaemia in piglets was considered to be due to umbilical haemorrhage. Anaemic piglets had a 36% mortality to weaning compared with 10% for non-anaemic piglets.(ABSTRACT TRUNCATED AT 250 WORDS)  相似文献   

16.
Colostrum-deprived piglets inoculated with rotavirus 24 h after birth developed a profuse diarrhoea that spread to non-inoculated, colostrum-deprived litter mates and, occassionally, to colostrum-fed piglets. Case fatality rates in these 3 categories of piglets were 63.2%, 35.7% and 8.3%, respectively. Surviving piglets recovered in 1-2 weeks, but shedded virus via the faeces for up to 3 weeks p.i. The D-xylose test revealed severe malabsorption, with extremely flat absorption curves for up to 3-4 weeks p.i. Malabsorption was more marked in piglets with a long-lasting faecal virus excretion than in piglets where virus disappeared from the faeces within 10 days p.i. Infected piglets (colostrum-fed and colostrum-deprived) had decreased weight gains and were 5 days older at a bodyweight of 25 kg than non-inoculated controls. It is concluded that rotavirus is probably of significance in diarrhoeal syndromes in suckling piglets, alone or in combination with E. coli or other pathogens.  相似文献   

17.
试验旨在开发能够有效预防和治疗仔猪细菌性腹泻和病毒性腹泻的卵黄免疫球蛋白粉相关产品,将卵黄抗体的先进技术更好地应用于畜牧养殖中。采用两种复合型卵黄免疫球蛋白粉对人工感染细菌(ETEC)和病毒(PEDV和TGEV)的21日龄断奶仔猪进行预防和治疗试验。将复合型卵黄免疫球蛋白粉Ⅰ型按0.4%添加至仔猪断奶日粮中,攻毒后仔猪没有出现死亡情况,只有5头仔猪在攻毒初期出现轻微腹泻情况,随着饲喂的继续,5头仔猪腹泻很快得到控制,而攻毒对照组仔猪全部死亡;对21日龄仔猪攻毒,攻毒24h内仔猪陆续出现腹泻症状。在攻毒24h后采用复合型卵黄免疫球蛋白粉Ⅱ型产品以1∶3的比例配以葡萄糖生理盐水进行灌服治疗,经3d治疗后仔猪腹泻情况得到很大的改善,5d后腹泻仔猪基本痊愈,治愈率可达84%~88%。对存活仔猪进行带毒检测,结果显示,预防组存活仔猪带毒水平较其他组更低,治疗组其次,而药物治疗对照组带毒情况严重。  相似文献   

18.
Distribution and persistence of four different strains of transmissible gastroenteritis (TGE) virus in newborn piglets were compared.The piglets inoculated with high-passaged TO-163 strain did not show any clinical signs of TGE on any days postinoculation (DPI), but the piglets inoculated with one of the other three strains, SH-14, SH-164 or TO-16, had soft feces or diarrhea. In the latter cases, the virus was isolated mainly from respiratory organs, lymph nodes, and digestive tract on any DPI, but was rarely detected in the digestive tract of piglets inoculated with the TO-163 strain. The frequency of virus recovery from the tissues was the highest till 4 DPI in all of the piglets inoculated with one of the four virus strains, and it was markedly reduced thereafter in the piglets inoculated with high-passaged strains.The TO-163 strain was subjected to serial passage in newborn piglets for seven passages. There was no evidence of regained pathogenicity with advance in passage, and detection of virus was restricted to lymph nodes and lung of these piglets.In gnotobiotic piglets inoculated with the TO-163 strain, frequent virus recovery and high titers of virus from the tissues were obtained on up to the 4th DPI. The viruses in high titer were found in the digestive tract of some of the piglets; however, none of them showed any clinical signs of TGE.  相似文献   

19.
The putative immunosuppressive effect of PRRS virus (PRRSV) on innate immune responses was studied in piglets infected in utero with PRRSV. Phagocytosis and oxidative burst capacities in 2-, 4- and 6-week-old in utero infected piglets were investigated and compared with age-matched control piglets. Phagocytic capacity of blood monocytes against Salmonella bacteria was investigated by flow cytometry. Oxidative burst in blood monocytes and in alveolar lung macrophages was investigated by luminol- and lucigenin-enhanced chemiluminescence, respectively. Decreased phagocytosis against Salmonella was found in blood monocytes from 4- and 6-week-old infected piglets compared to controls. In contrast, 2-week-old infected piglets showed phagocytic responses comparable to age matched control piglets. While oxidative burst capacity was increased in blood (PBMC) from in utero PRRSV infected piglets, the oxidative burst capacity of alveolar lung macrophages was decreased, especially in 2- and 4-week-old piglets, compared to age-matched control piglets. The present results indicate that in utero infection with PRRSV inhibits phagocytosis against Salmonella in blood monocytes as well as the oxidative burst capacity of alveolar macrophages. These observations indicate that PRRSV in utero infection induces at state of immunosuppression in piglets paving the way for enhanced secondary infections.  相似文献   

20.
This study was conducted to compare physiological characteristics between Meishan and Yorkshire piglets in their early lives. Six healthy purebred Meishan sows and Yorkshire sows with close farrowing dates were used in this research. The piglets sucked their respective sow's milk for 14 days, then they were slaughtered to collect samples of blood, pancreas, contents of stomach, jejunum, cecum, colon as well as feces for analysis of blood biochemical parameters, digestive enzymes, and volatile fatty acid(VFA). The results showed that Yorkshire piglets had higher concentrations of high-density lipoprotein cholesterol(HDL-C) and total cholesterol(TC)(P 0.05). Gastric lipase activity was higher in Meishan piglets but Yorkshire piglets had higher lactase activity(P 0.05). The total VFA together with acetate and propionate in cecum and colon were higher in Meishan piglets than in Yorkshire piglets(P 0.05),but acetate in jejunum and ratio of acetate to propionate in colon were lower in Meishan piglets than in Yorkshire piglets(P 0.05). In conclusion, in early suckling period, significant differences exist in host metabolism and intestinal microbial metabolism between Meishan and Yorkshire piglets.  相似文献   

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