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1.
Human asthma is not a curable disease, although spontaneous resolution is common in adult asthmatics who developed asthma in childhood. We do not know if this is true or not for cats with asthma. We do know that some cats may be only mildly and intermittently symptomatic and that others may suffer life-threatening illness. An important new development in our understanding of this disease is the occurrence of airway inflammation even when patients are symptom-free. It is therefore crucial that we direct our therapeutic attention toward the underlying chronic inflammation that causes the acute clinical signs of cough, wheeze, and increased respiratory effort. Client education is also critical so that our clients develop realistic expectations of the effectiveness of these treatments for their pets. A great deal still needs to be learned regarding the pathogenesis of feline asthma and the optimal approach(es) to treating cats with this sometimes debilitating and potentially fatal respiratory syndrome. There is great hope and anticipation that ongoing research can bring new treatments for human and feline asthmatics alike.  相似文献   

2.
Sir, — It may be of interest to some rural practitioners, having an upsurge in requests for opthalmoscopic examinations of working dogs, to know that at present this practice is engaged in examinations at the National dog trials. Retinal disease is an increasing problem in both Huntaways and Heading dogs in this country. This is probably a result of the extensive use of selected strains and the tendency for the breeds to become more uniform with farmers keeping fewer better-bred dogs. Work on this complex condition is however in its infancy, and a great deal is yet to be resolved. At this stage histological sectioning suggests an inflammatory component, but computer pedigree analysis suggests a heretibility of 0.33 — 0.40. In the main the condition is not analogous to central P.R.A. present in the British Border Collie, despite its ancestral contribution particularly to the Heading dog.  相似文献   

3.
In conclusion, replacement gilts should be finally selected before 110 kg body weight and should have been stimulated to reach puberty by this time. Currently, the best method for achieving this is ad libitum feeding and the correct use of boar exposure. However, whether ad libitum feeding will always be the best feeding strategy remains to be seen. The impressive success of selection programs and the potential for the use of growth promoters and repartitioning agents in the feeder barn may require that future replacements be identified at an early stage and raised under a separate feeding regimen. To produce a large first litter, gilts should be bred at their second estrus. There is unlikely to be any further increase in litter size by delaying mating to third estrus. A major consideration when choosing when to breed replacements is the length of their productive life. For many farms, this may be maximized by delaying breeding until the sow is 120 to 130 kg body weight with a minimum backfat depth of 18 mm. For the producer who is able to exert control over lactation condition loss, however, breeding replacements at about 110 kg body weight with backfat depths of 14 to 16 mm should not adversely affect long-term performance. Although it is true that, under some conditions, the lean gilt may become a problem, it is equally true that her potential is as great as her fatter contemporaries. Whether this potential is realized is largely under the producer's control. Regarding the boar, nutritional management need not vary from that provided for gilts. However, if replacement boars are raised on-farm, it is of great importance that they be allowed to socially interact with other pigs. Failure to provide this opportunity will result in a boar with reduced libido.  相似文献   

4.
Dogs with long-standing, chronic, recurrent otitis externa often represent one of the most frustrating types of problems in daily clinical practice. The important aspect of this discussion is that the clinician may be presented with a patient in which the primary chief complaint is otitis externa but a wide variety of disease processes may be causing the problem, including various combinations of the primary, predisposing, and perpetuating causes as discussed previously. The use of a thorough history and general and dermatologic physical examinations often leads the clinician to establish a systematic approach to identify the specific underlying problems. Until this is accomplished, the recurrent nature of the otitis externa will remain as a persistent problem.  相似文献   

5.
By this review we commemorate professor dr. dr. h.c. G.H.B. Teunissen, who died on August 20, 1998. We report his important role in the development of human and small animal thoracic surgery in the Netherlands following his appointment as professor in the Small Animal Clinic of the State University of Utrecht in January 1947. Comparing Teunissen's publications on thoracic surgery with other literature on this subject in the same period shows that he was aware of and made use of the possibilities of the developments at that time. Thanks to his contributions, the small animal thoracic surgery in Utrecht is internationally recognized.  相似文献   

6.
Distemper and rabies vaccination are highly recommended because of the almost invariable fatal outcome of these conditions. Vaccination should constitute an important part of a ferret's preventative medicine program. With the current and anticipated development and licensing of new vaccines, practitioners are invited to gain awareness of the latest vaccine information. Establishment of a practice vaccination protocol with regards to the site of administration of rabies and distemper vaccines is paramount to document any future abnormal tissue reactions. Influenza is the most common zoonotic disease that is seen in ferrets. Although it generally is benign in most ferrets, veterinarians must take this condition seriously. The characteristic continuous antigenic variation of this virus may lead to more virulent strains; the recent emergence of avian influenza virus outbreaks; and the increased susceptibility of elderly, young, and immunosuppressed individuals.  相似文献   

7.
The purpose of this article is to review the use of cold, heat, therapeutic ultrasound, and electrical stimulation in small animal rehabilitation.The material in this article is a compilation from the veterinary and hu-man literature. Additional information is needed on how to adapt the techniques used in human beings to small animals and then to establish the efficacy of these techniques in animals.  相似文献   

8.
The molecular basis of the pathophysiology of anhidrosis is still not well understood. Therefore, treatments are more often based on clinical impressions than on scientific fact. Treatment options for this condition will improve only when more is known about the molecular events that cause anhidrosis, especially as they relate to beta2-receptor dysfunction and stimulus-secretion coupling in the sweat glands of affected horses. Although this additional information is being attained, sound environmental management will continue to be a very important aspect of the treatment of horses affected with anhidrosis.  相似文献   

9.
10.
In this article, "Invertebrates" are considered to be all those animals that are not in the five main groups of vertebrates (Mammalia,Aves, Reptilia, Amphibia, and three classes of fish), and the term neoplasm is used in its traditional sense of "new, uncontrolled, growth". The history of study of such lesions is reviewed and methods of investigation and control are outlined.  相似文献   

11.
Pharmacogenetics, the study of genetic determinants of response to drug therapy, is likely the ultimate way to establish the right drug and dose for each patient, thereby optimizing efficacy and minimizing toxicity. Despite the fact that this branch of pharmacology is still in its infancy as a science, a number of important discoveries have already contributed to improved pharmacotherapy in human and veterinary patients.  相似文献   

12.
A new inactivated anti-brucellosis vaccine, prepared according to a process previously described under the name of P.B. has been carried out from the strain Brucella melitensis Rev. 1 Elberg. The absence of agglutinogen content was verified through rabbits and mice. Its immunogenic content, tested on DBA2 mice by means of an infection test, produced excellent results. Tests were planned for sheep. If the results on this species were satisfactory, this type of vaccine could then better replace the live vaccine Rev 1 which, in addition to the post-vaccine agglutinines which it takes after, is not without danger to man.  相似文献   

13.
In 2004, the isolation of an influenza virus from racing greyhounds changed the point of reference for discussions about influenza virus in dogs. A virus isolated from greyhounds did not have its origin in a previously described human influenza virus but came from a virus with an equine history. More significantly, evidence emerged to indicate that the virus was capable of transmission from dog to dog. This virus is now referred to as canine influenza virus (CIV) and is the focus of this review. Because the history of CIV is relatively short, the impact of this virus on canine health is yet to be determined.  相似文献   

14.
In the European Union and elsewhere there is a requirement to ascribe causality to adverse drug reactions which occur in treated animals. In the EU, the ABON system of causality assessment is used but the assignment of causality assigned is not always self evident, and it may be complicated for a variety of reasons. In this paper, the approaches to causality assessment, based on a number of key criteria which examine the administration of the drug in relation to the sequence of ensuing events and the presence of biological plausibility are examined, along with the utility of using algorithms to facilitate this process. Unexpected adverse drug reactions usually require expedited reporting, depending on national or regional regulatory requirements. Again, deciding on what might constitute an expected (or unexpected) adverse reaction, particularly when a product may be intended for use in a number of species, and when within any one species a number of breeds may be treated, is not necessarily a straightforward issue. However, an approach to facilitate the decision- making process, based on a similar approach used in the pharmacovigilance of human medicinal products is discussed.  相似文献   

15.
16.
Chronic bronchitis is a frustrating disease because the cause is rarely determined, the pathologic changes that accompany and define the disease are usually nonreversible and often progress to life-threatening disorders, and there is a lack of direct scientific evidence for the treatment recommendations that have been offered for the management of this disease in dogs. This article reviews the pathophysiology, clinical presentation, diagnosis, and evaluation of chronic bronchitis in dogs. Important diagnostic tools for use in diagnosis are discussed, including clinical pathology, chest radiographs, and culture and cytology of airway fluid samples.  相似文献   

17.
Investigation of a fish kill should begin with water quality analysis and use of standard necropsy techniques to rule out the role of parasites or bacteria. The presence of a virus does not mean necessarily that it is a pathogen. Another point to consider is the potential influence of water temperature on pathogenicity; this may be an important factor in developing disease. A list of laboratories that is approved by the USDA to conduct diagnostic testing of aquaculture species can be found at: http://www.aphis.usda.gov/vs/nvsl/labcertification/aquaapplab.htm.  相似文献   

18.
Ixodes (Afrixodes) drakensbergensis n. sp., is described from females, males, nymphs and larvae collected on a drag at Giant's Castle Nature Reserve, Natal, Republic of South Africa; it was also taken from an eland in the same area and from goats and a cow in the adjacent Tank Area 118. The occurrence of I. (A.) drakensbergensis on domestic animals suggests that it may be of economic importance in this area. Information is provided to separate the new species from other closely related Ixodes species that occur or may occur in this region.  相似文献   

19.
Crown reduction is a sterile endodontic procedure indicated for reducing the crown height of teeth. The procedure is used primarily on canine teeth as a disarming technique in aggressive biting pets or to treat traumatic occlusion. Recommendations for using this technique for biting pets are described.  相似文献   

20.
Topical administration of drugs is the treatment of choice for diseases of the anterior segment. Drug levels attained by this means are usually of short duration, however, necessitating frequent therapy or continuous perfusion if prolonged drug levels are required. A drug-delivery device (collagen shield or contact lens) or subconjunctival injections can be used to augment topical therapy if frequent treatment is not possible. Subconjunctival injections are recommended for drugs that have low solubility and, hence, low corneal penetration. Retrobulbar injections are seldom indicated, except for regional anesthesia. Systemic administration is useful for anti-inflammatory therapy but it may be difficult to establish therapeutic levels of antibiotic agents in the eye because of the blood-ocular barrier. In severe cases, intraocular injection may be required.  相似文献   

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