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1.
Metabolic rate and energy consumption increase through the activation of the hypothalamic-pituitary-adrenal axis when an animal is exposed to a stressor. Residual feed intake (RFI) as a measure of efficiency has been shown to be related to exogenous adrenocorticotropin hormone (ACTH)-stimulated cortisol concentrations, which is indicative of the relationship between an animal's response to stress and the efficiency with which the energy is used for growth and production. In this study, we tested the hypothesis that sheep with low post-ACTH serum cortisol concentration relative to the other sheep in the flock have lower RFI values and lower cortisol concentrations following insulin-induced hypoglycemia. Adrenocorticotropin hormone (2.0 μg/kg body weight)-stimulated cortisol concentrations were measured in 100 sheep. The extreme responders were selected (n = 12 high cortisol, n = 12 low cortisol), and feed efficiency and body composition parameters were measured. A second ACTH challenge and an insulin challenge were administered. More efficient sheep (more negative RFI value) were found to have lower (P < 0.05) cortisol concentrations following both an ACTH challenge and an insulin challenge. Low-cortisol sheep (low response to ACTH or insulin) were found to have a lower (P < 0.05) proportion of fat tissue in comparison to the high-cortisol animals. These data clearly indicate that an animal's response to exogenous ACTH or insulin-induced hypoglycemia as a stressor is related (P < 0.05) to efficiency of energy use when measured as RFI. These data have important implications in enabling identification of animals that are superior in terms of feed efficiency and for understanding the physiological mechanisms underlying efficiency of energy use. 相似文献
2.
Chronic elevation of glucocorticoid concentrations is detrimental to health. We investigated effects of chronic increase in plasma cortisol concentrations on energy balance and endocrine function in sheep. Because food intake and reproduction are regulated by photoperiod, we performed experiments in January (JAN) and August (AUG), when appetite drive is either high or low, respectively. Ovariectomized ewes were treated (intramuscularly) daily with 0.5 mg Synacthen Depot® (synthetic adrenocorticotropin: ACTH) or saline for 4 wk. Blood samples were taken to measure plasma concentrations of cortisol, luteinising hormone (LH), follicle-stimulating hormone (FSH), growth hormone (GH), leptin, insulin, and glucose. Adrenocorticotropin treatment increased concentrations of cortisol. During JAN, treatment reduced food intake transiently, but increased food intake in AUG. Leptin concentrations were reduced and glucose concentrations were greater in AUG, and insulin concentrations were similar throughout the year. Treatment with ACTH increased leptin concentrations in AUG only, whereas insulin concentrations increased in JAN only. Synacthen treatment increased glucose concentrations, with a greater effect in JAN. Changes in truncal adiposity and ACTH-induced cortisol secretion were positively correlated in JAN and negatively correlated in AUG. Treatment reduced the plasma LH pulse frequency in JAN and AUG, with an effect on pulse amplitude in JAN only. Treatment did not affect plasma GH or FSH concentrations. We conclude that chronically elevated cortisol concentrations can affect food intake, adiposity, and reproductive function. In sheep, effects of chronically elevated cortisol concentrations on energy balance and metabolism depend upon metabolic setpoint, determined by circannual rhythms. 相似文献
3.
Two studies were conducted to determine the relationship of feeding behavior to a phenotypic expression of residual feed intake (RFI), a measure of efficiency. In Exp. 1, a feedlot diet containing roughage was fed (traditional). In Exp. 2, a no-roughage diet was fed. Residual feed intake, a measure of feed efficiency, was calculated for both studies. In Exp. 1, six feed-efficient (low RFI) steers and six feed-inefficient steers (high RFI) were selected from a contemporary group of 80 steers, and feeding behaviors were analyzed. In Exp. 2, nine feed-efficient and eight feed-inefficient steers were selected from a contemporary group of 40 steers. There were no differences (P > 0.13) in initial or final BW or ADG between efficient and inefficient groups in either Exp. 1 or 2. In Exp. 1, DMI and average eating bouts daily differed (P < 0.001), with efficient steers consuming less feed and eating fewer times per day. In Exp. 2, efficient steers consumed less (P < 0.001) feed, and average eating bouts daily tended (P = 0.07) to be fewer in efficient animals. Limited differences were noted in feeding behavior between groups, with inefficient steers from both studies having a more variable eating pattern throughout the day. The average daily eating rate did not differ (P > 0.20) between groups in either experiment. The average number of days comprising a feeding pattern for both efficiency groups in Exp. 1 and 2 was found to be 2 to 3 d and multiples of 2 to 3 d. In Exp. 1, the feed intake pattern of efficient and inefficient steers changed once they reached a BW of approximately 391 and 381 kg, respectively. This occurred near d 47 for the efficient steers and near d 32 for inefficient steers. In Exp. 2, the feed intake pattern of both efficient and inefficient steers changed once they reached a BW of approximately 399 kg, which occurred on d 31 for the efficient steers and on d 33 for the inefficient steers. From the measured variables, there were no differences in growth and limited differences noted in feeding behavior between efficient and inefficient groups. The results of the trials suggest increased variability of feed intake throughout the day for inefficient animals. 相似文献
4.
The relationship within and between production performance and meat quality characteristics in pigs from three different genetic lines 总被引：1，自引：0，他引：1
Ninety-six pigs from Large White (LW), Synthetic Genex 3000 (SG) and Meishan-derived dam line (M) genetic lines, each with a mean live body weight (BW) of 20.7 ± 4.2 kg, were used to investigate the relationship that exist between production performance and meat quality parameters for these three genotypes. The animals were assigned to pens in groups of eight and slaughtered at 109.6 ± 3.78 kg BW. At the end of the trial, the LW pigs had the highest (P < 0.001) average daily feed intake and average daily gain and protein deposition rates, the M pigs showed (P < 0.001) the worst feed conversion, the highest daily backfat gain and the lowest residual energy intake, and the SG pigs had the lowest (P < 0.001) daily fat deposition rate. The longissimus muscle of the M pigs had higher a (P < 0.01) and b (P < 0.05) values than the LW pigs, with the SG pigs in between. The M loins also had the highest (P < 0.01) shear force value, which may be explained by the lower (P < 0.01) soluble collagen content. In spite of their lowest fat deposition rate, the highest (P < 0.001) intramuscular fat content was measured in the SG loins, and the highest (P < 0.01) protein content was found in the M loins. Eight canonical correlations were obtained between performance and meat quality data, with the first three correlation coefficients of 0.87, 0.66 and 0.64 being significant. Performance and meat quality data were related to a certain extent. Pigs with a higher average daily feed intake also had a higher average daily gain, an average protein deposition rate, residual energy intake and gain-to-feed ratio, and lower meat dry matter, intramuscular fat, a values and pigment content. Body water content seems to be higher in fast-growing pigs. Furthermore, fast-growing pigs also have lower intramuscular fat, a values and pigment content. However, there is some indication that the magnitude of these correlations can be breed-dependent. The differences among the studied genotypes are much higher in terms of growth performance than in terms of meat quality traits. 相似文献
5.
Morrison CD Wood R McFadin EL Whitley NC Keisler DH 《Domestic animal endocrinology》2002,22(2):103-112
In sheep, serum concentrations of leptin change congruently with increases or decreases in nutritional status, while intracerebroventricular infusions of leptin dramatically suppress feed intake in well-fed lambs, and may also increase growth hormone (GH), and/or luteinizing hormone (LH) in undernourished lambs. The objective of the present study was to determine the effects of peripherally delivered ovine leptin, via intravenous infusions, on feed intake and serum concentrations of GH, LH, insulin, IGF-1, cortisol, and thyroxine. Twelve ewe lambs weighing 29.4 +/- 0.7 kg were infused intravenously with a linearly increasing dose of leptin or saline (n = 6 per group) for 10 days, reaching a maximum dose delivered of 0.5mg/h on day 10. Feed intake was assessed twice daily, and blood samples were collected every 10 min for 6 h on days 0, 2, 5, 8, and 10. Serum concentrations of leptin increased in leptin-treated lambs by day 2 (P = 0.05), and continued to increase to concentrations 9-fold greater than saline-infused lambs by day 10 (P < 0.001). Despite the substantial increase in serum leptin, feed intake did not differ between leptin and saline-infused lambs except on day 3.5 (P = 0.01). Furthermore, intravenous infusions of leptin did not significantly influence serum concentrations of insulin, cortisol, IGF-1, thyroxine, LH, or GH. Collectively, these observations contrast with the potent hypophagic effects of leptin when delivered intracerebroventricularly into well-fed lambs. The reasons for the disparate response of lambs treated intravenously with leptin, versus that reported for lambs treated intracerebroventricularly with leptin are not known, but may provide insight into the mechanism(s) of leptin resistance. 相似文献
6.
7.
为探索云南半细毛羊在长期繁衍后有无种质退化现象。选择体重在14kg左右的云南半细毛羊春羔22只进行放牧饲养试验,以测定其生产性能及对牧草营养物质的利用效率。结果发现云南半细毛羊增重是生长后期高于生长前期;日采食量是生长前期略高于后期;每增重1g所需要采食牧草量生长后期低于生长前期;对采食牧草营养物质的消化率,其生长后期均小于前期;血清生化指标则是后期高于前期;血清生长激素和胰岛素的含量生长前期均高于生长后期,但甲状腺激素（T3、T4）则生长前期低于生长后期。从性别角度看,母羊的增重和采食牧草量低于公羊,但每增重1g所需要采食牧草量生长前期公羊低于母羊,后期公羊高于母羊;血清生化指标是母羊高于公羊,血清中的生长激素和甲状腺激素母羊含量均比公羊高,而胰岛素的含量则是在生长前期,母羊低于公羊,而在生长后期母羊高于公羊。说明母羊虽然营养物质合成较快,但其营养物质大部分都用在了氧化供能上,也就是说其基础代谢较为旺盛,而且公羊虽然营养物质合成较慢,但其基础代谢较缓慢,所以表现其体重增加比母羊快。 相似文献
8.
The purpose of this paper is to review our understanding of the involvement of central and peripheral factors in the control of feed intake in ruminants. The regulation of body weight under various states of energy need depends on an animal's ability to control feed intake to meet these needs. In the central nervous system (CNS), the ventromedial and lateral hypothalamus appear to be the areas involved in satiety and hunger, respectively; other important areas are the paraventricular nucleus and rostral brain areas. Intracerebroventricular injection of neurotransmitters, alpha- and beta-adrenergic agonists, 5-hydroxytryptamine and gamma aminobutyric acid (GABA) agonists, has stimulated feeding in ruminants; intravenous administration of benzodiazepines stimulated feed intake in sheep and cattle, possibly by increasing GABA levels in the brain. Neuropeptides of the opioid and cholecystokinin families have reciprocal hunger-stimulating and satiety-eliciting effects when administered centrally in sheep. Further, concentrations of these neuropeptides in specific areas of the hypothalamus have been shown to change with the state of hunger-satiety of sheep. In the periphery, none of the hormones associated with the pituitary, adrenal gland, pancreas or gastrointestinal tract has been shown to have significant effects on the control of feed intake. In addition, the physical properties of the ingested feed in the gastrointestinal tract, while possibly influencing the rate or pattern of feeding, do not appear to be primary factors in the control of feed intake under many feeding conditions.(ABSTRACT TRUNCATED AT 250 WORDS) 相似文献
9.
Cook CJ 《New Zealand veterinary journal》1999,47(2):67-70
AIMS: As kappa(kappa)-opioids have marked effects on pain threshold in sheep during oestrus, late pregnancy and after birth, a study was undertaken to determine if kappa -opioids also had other roles during these states. METHODS: Opioid agonists (GR89696, DAMAGO) were administered into either the lateral hypothalamus (LH) or amygdala of non-pregnant sheep (n = 5) or pregnant sheep (n = 15) in late pregnancy (n = 5) within 12 h of birth (n = 5) or in the third week after birth (n = 5). Cortisol, behavioural and electrocardiographic responses to an auditory stimulus were assessed with and without drug administration, as was feed consumption and suckling events. RESULTS: In non-pregnant sheep, DAMAGO injected into either the LH or amygdala had little effect on the response to the auditory stimulus but when injected into the LH did decrease food consumption. GR 89696 had no obvious effects. In late pregnancy, cortisol and heart rate responses to the auditory stimulus were significantly reduced compared to the non-pregnant animals irrespective of treatment. This was also the case in the third week after birth. Immediately post-partum cortisol responses were closer to that seen in the non-pregnant animal. In late pregnancy and both post-partum periods, GR 89696 in the LH significantly increased feed consumption while DAMAGO had no significant effects. GR 89696 injected into the amygdala reduced the behavioural response to the auditory stimulus in late pregnancy and both post-partum periods. CONCLUSION: Changes in sensitivity to opioids occur in both the amygdala and LH with pregnancy and after birth. These may influence maternal behaviours and feed intake. 相似文献
10.
Y.R. Montanholi R. Palme L.S. Haas K.C. Swanson G. Vander Voort S.P. Miller 《Livestock Science》2013,155(1):130-136
Improvement in the utilization of feed in livestock is an important target of breeding and nutritional programs. Recent evidence indicates a potential association between feed efficiency and fecal cortisol metabolites, which could eventually be used as an indirect assessment of this trait. This evidence is more comprehensively evaluated in here with samples for plasma cortisol (PC; ng/ml) and fecal cortisol metabolites (FCM; ng/ml) collected more often during the entire finishing phase in beef steers. Individual daily feed intake of 112 steers fed a high-moisture corn-based and haylage diet was measured over 168 d. Body weight, blood and fecal samples were collected every 14 d and ultrasound measures of backfat thickness and longissimus muscle area were taken every 28 d. Four productive performance traits were calculated: daily dry matter intake (DMI), average daily gain (ADG), feed to gain ratio (F:G) and residual feed intake (RFI). At the end of the feedlot phase, steers were ranked according to RFI and samples were analyzed for PC and FCM from the 32 steers with greatest and 32 steers with lowest feed efficiency. In addition, a sub-group of 12 steers from each of these two groups with divergent feed efficiency were subjected to hourly blood sampling for 24 h. Less efficient steers had greater DMI, F:G and consumed 1.5 kg/d more DMI (P<0.05) than steers with improved feed efficiency. No differences (P>0.10) in PC over the 12 biweekly sampling periods between steers with divergent feed efficiency were observed. However, a trend toward significance between 19:00 and 02:00 h over the hourly sampling evaluation was noticed, with the sub-group of more feed efficient steers presenting higher levels of PC in this period of the day (P=0.08). On the other hand, FCM levels displayed a distinct pattern between RFI groups over the biweekly sampling period, with more efficient cattle presenting greater levels of these metabolites (P<0.05). This study reinforces the positive association between improved feed efficiency and FCM levels over the finishing phase; and the lack of association between feed efficiency and PC when single samples are collected every two weeks through a single jugular venipuncture performed after handling the cattle for sampling. Further studies to develop sampling protocols for assessing FCM as an indicator trait for feed efficiency are warranted, as well as, studies to understand the role of endogenous glucocorticoids in the performance of the bovine. 相似文献
11.
de Figueiredo Darcilene Maria Mercadante Maria Eugênia Zerlotti Pires Aldrin Vieira Branco Renata Helena Ribeiro Enilson Geraldo Dallago Gabriel Machado Schorer Marianne Rocha Pedro Ribeiro 《Tropical animal health and production》2019,51(2):449-456
This study aimed to compare feed efficiency measures of Nellore beef cattle on different residual intake and gain (RIG) classes. We used data from 610 animals weighing on average 236.33 kg and average of 283 days of age from feedlot performance tests carried out between 2005 and 2012. Animals were grouped based on RIG into three different classes: high RIG (>?mean?+?0.5 standard deviation (SD), most efficient; n?=?193), medium RIG (mean?±?0.5 SD; n?=?235), and low RIG (<?mean – 0.5 SD, least efficient; n?=?182). Residual feed intake (RFI), residual gain (RG), feed conversion ratio (FCR), feed efficiency (FE), relative growth rate (RGR), and Kleiber ratio (KR) of animals in each RIG class were compared by Tukey test at 1% of probability. Phenotypic correlations between variables were evaluated as well. Animals on high RIG class showed lower dry matter intake (P?<?0.01) and higher average daily gain (P?<?0.01) than low RIG animals. Consequently, high RIG animals had lower FCR (P?<?0.01) and higher FE (P?<?0.01) than those animals in low RIG class. The most efficient animals based on RIG were also the most efficient animals based on RG and RFI. RIG was negatively correlated to dry matter intake (P?<?0.01) and FCR (P?<?0.01), and a positive correlation was found between RIG and FE (P?<?0.01). Therefore, RIG appears to be a good parameter to select animals with reduced dry matter intake and high productive performance.
相似文献12.
Residual energy intake, defined as actual minus predicted energy intake during a production period, was estimated for each of 650 bull calves of 31 Holstein Friesian or Brown Swiss sires. Residual energy intake, measured under ad libitum feeding, had heritabilities similar to those of growth rate and energy conversion ratio with an estimate of approximately .3. Residual energy intake was related to average daily energy intake both phenotypically and genetically such that selection for decreased residual energy intake would lead to a decrease in daily feed intake. Such selection would also tend to increase carcass fatness (i.e., genetically fat animals are the most efficient). Residual energy intake estimated with and without correction for carcass composition were closely correlated. Thus, residual energy intake may be estimated without the knowledge of carcass composition in growing bulls of dual-purpose breeds. 相似文献
13.
Tewodros Eshete Solomon Gizaw Eyassu Seifu 《Tropical animal health and production》2012,45(1):177-184
The experiment was conducted to determine feed intake, digestibility, body weight change, carcass characteristics, and sensory quality of meat of Menz sheep supplemented with a concentrate mix and combinations of different proportions of tossign (Thymus serrulatus). Twenty yearling intact male Menz sheep were divided according to their initial body weight into five blocks of four animals in a randomized block design, and treatments were assigned randomly to each sheep within each block. The treatments were a basal diet of hay alone (T1) and supplemented with 300 g concentrate mix (T2), 200 g concentrate mix?+?100 g tossign (T3), and 100 g concentrate mix?+?200 g tossign (T4) on a dry matter basis. The results indicated that supplementation of tossign together with concentrate mix significantly increased (P?<?0.001) feed intake and improved DM and nutrient digestibility compared to the non-supplemented group. Supplementation of tossign with concentrate significantly improved (P?<?0.001) daily weight gain, feed conversion efficiency, and carcass characteristics of sheep compared to the non-supplemented group. Flavor and aroma scores of meat samples of sheep in T3 and T4 were significantly higher (P?<?0.001) than the corresponding values in T1 and T2. The scores for tenderness, juiciness, and degree of marbling of meat samples of sheep were significantly higher (P?<?0.001) in T3 and T4 compared to meat samples of sheep in T1. Inclusion of small amounts of tossign as additive in concentrate mix supplementation can improve the sensory quality of meat of Menz sheep. 相似文献
14.
Sartin JL Marks DL McMahon CD Daniel JA Levasseur P Wagner CG Whitlock BK Steele BP 《Journal of animal science》2008,86(10):2557-2567
Melanocortin-4 receptors (MC4R) are key factors in the depression of appetite during disease. This study was designed to determine the role of agouti-related protein (AgRP) in the effect of endotoxin (lipopolysaccharide, LPS) on appetite. Sheep received an intracerebroventricular injection of either saline or AgRP (0.5 nmol/kg of BW) 1 h before intravenous injection of either saline or LPS (0.6 microg/kg of BW) at time 0 and again at 4 h. Agouti-related protein prevented the reduction in feed intake due to LPS (P < 0.05). In a second experiment, AgRP gene expression was unaffected at 3 h and increased (P < 0.01) at 6 h after LPS. Immunohistochemical evidence indicated that there was an increase in the percentage of AgRP neurons with c-Fos immunoreactive nuclei 6 h after sheep were injected with LPS (P < 0.04) and a corresponding decrease in a-melanocyte-stimulating hormone neurons coexpressing c-Fos (P < 0.001). In situ hybridization provided evidence for an increase in AgRP gene expression and a decrease in proopiomelanocortin gene expression 6 h after LPS (P < 0.05). In a final experiment, physiological elevation of orexigenic agents by short-term fasting kept feed intake at the same level as controls, in spite of the presence of LPS, similar to the effects of AgRP in Exp. 1. The AgRP inhibition of the MC4R prevents appetite inhibition in response to LPS and well after LPS inhibition of feed intake, both AgRP and a-melanocyte-stimulating hormone may change in a pattern that favors appetite increases. These studies support the notion of the MC4R as a critical component of the mechanism for appetite suppression due to endotoxin. 相似文献
15.
Dose–responses of zinc–methionine supplements on growth,blood metabolites and gastrointestinal development in sheep 
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下载免费PDF全文 N. Jafarpour M. Khorvash H. R. Rahmani A. Pezeshki M. Hosseini Ghaffari 《Journal of animal physiology and animal nutrition》2015,99(4):668-675
The effects of zinc–methionine (Zn‐Met) supplementation on growth, blood metabolites and gastrointestinal development were investigated in two experiments with sheep. The objective of Experiment 1 was to determine the effects of Zn‐Met supplementation on hormones and metabolites involved in growth and energy balance regulation, while Experiment 2 aimed to determine the effects of Zn‐Met on feed intake, body weight, gastrointestinal development and liver glycogen concentration in lamb. The animals were assigned to groups with different concentrations of dietary Zn‐Met (0, 0.4, 0.8 and 1.2 g/day) in both experiments. In Experiment 1, feeding different doses of Zn‐Met increased plasma insulin‐like growth factor 1 (IGF‐1) concentration, but it linearly decreased plasma growth hormone (GH). No differences were observed in blood cortisol, insulin and glucose concentrations among the treatments. In Experiment 2, addition of Zn‐Met to the diets did not lead to changes in the body weights of the lambs. Both average daily gain and dry matter intake (DMI) increased linearly with increasing concentrations of dietary Zn‐Met. Lambs receiving Zn‐Met showed higher liver glycogen concentrations than the control. While significant increases were observed in the villus height and crypt depth in the duodenum and jejunum as a result of Zn‐Met supplementation, no change was detected in blood glucose concentrations (p > 0.05). Our findings suggest that dietary Zn‐Met may improve growth, energy balance and gastrointestinal development in sheep. 相似文献
16.
Crowley JJ Evans RD Mc Hugh N Pabiou T Kenny DA McGee M Crews DH Berry DP 《Journal of animal science》2011,89(11):3382-3393
Interest in selection for improved feed efficiency is increasing, but before any steps are taken toward selecting for feed efficiency, correlations with other economically important traits must first be quantified. The objective of this study was to quantify the genetic associations between feed efficiency measured during performance testing and linear type traits, BW, live animal value, and carcass traits recorded in commercial herds. Feed efficiency data were available on 2,605 bulls from 1 performance test station. There were between 10,384 and 93,442 performance records on type traits, BW, animal value, or carcass traits from 17,225 commercial herds. (Co)variance components were estimated using linear mixed animal models. Genetic correlations between the muscular type traits in commercial animals and feed conversion ratio (-0.33 to -0.25), residual feed intake (RFI; -0.33 to -0.22), and residual BW gain (RG; 0.24 to 0.27) suggest that selection for improved feed efficiency should increase muscling. This is further evidenced by the genetic correlations between carcass conformation of commercial animals and feed conversion ratio (-0.46), RFI (-0.37), and residual BW gain (0.35) measured in performance-tested animals. Furthermore, the genetic correlations between RFI and both ultrasonic fat depth and carcass fat score (0.39 and 0.33, respectively) indicated that selection for improved RFI will result in leaner animals. It can be concluded from the genetic correlations estimated in this study that selection for feed efficiency will have no unfavorable effects on the performance traits measured in this study and will actually lead to an improvement in performance for some traits, such as muscularity, animal price, and carcass conformation. Conversely, this suggests that genetic selection for traits such as carcass quality, muscling traits, and animal value might also be indirectly selecting for more efficient animals. 相似文献
17.
《Livestock Production Science》1992,30(1-2):141-153
The influence of protein restriction and subsequent realimentation on protein and lipid depositionas studied. Between 28 kg and 65 kg live weight (LW ), entire male pigs of two strains (a commercial and a sire strain) were given diets either deficient or adequate in protein content. From 65 to 105 kg LW all pigs were fed a protein-adequate ration. Animals were slaughtered and dissected at start, 65 and 105 kg LW. Body composition and deposition rates of protein, lipid, lean and fatty tissue for both the restriction period (28–65 kg LW) and the realimentation period (65–105 kg LW) were calculated. Protein restriction reduced feed intake (28%), live weight gain (60%), and rate of protein (75%) and lipid deposition (15%) between 28 and 65 kg live weight. A165 kg, restricted animals had twice as much lipid and were 60 days older than controls. During realimentation, previously restricted pigs (compared to controls) had slightly (7%) reduced feed intake and 15% increased weight gain and efficiency. Protein deposition rate beyond 65 kg LW was increased by 13% and ratio of lipid to protein deposition was decreased from 1.69 to 1.23. At 105 kg, the previously restricted pigs still were older and fatter than controls, so compensation was not complete. Strains of pigs responded similarly to both restriction and realimentation. Dissection at 105 kg LW was not sensitive enough to show the effects revealed by chemical analysis. The experiment revealed that nutritional history may influence the relation between lipid deposition rate and protein deposition rate. 相似文献
18.
Randhir Singh Bhatt Nira Manik Soren Artabandhu Sahoo Shaikh Abdul Karim 《Tropical animal health and production》2012,45(1):167-176
Improvement in body condition was assessed in 40 cull ewes (>6 years), equally distributed in two groups and realimented with ad libitum roughage (gram straw) and two levels of concentrate feeding, i.e., 2.5 % (T1) of live weight (LW) and ad libitum (T2). Five representative animals from an initial 45 were slaughtered at the initiation of the study (0 day) and five animals from each treatment at 44, 67, and 90 days of experiment for carcass attributes. Improvement in body condition score (BCS), nutrient utilization, feed efficiency, and carcass traits were assessed at 44, 67, and 90 days. Metabolism trial of 6-day collection of feed, feces, and urine samples was conducted on five representative ewes from each group after 60 days of feeding. The level of concentrate feeding on LW gain and BCS was significant, and the duration of realimentation showed a linear improvement (P?<?0.001). The digestibility and intake of dry matter, organic matter, and crude protein was higher (P?<?0.05) in T2. The N intake, absorption, and balance showed a similar trend. Increase (P?<?0.05) in total N, trichloroacetic acid precipitable N, and ammonia N was observed with extension of realimentation period. Blood metabolic profile also showed improvement (P?<?0.05) from an undernourished state to normal after alimentation. Animals in T2 accumulated higher LW with minimal expenditure of metabolizable energy (73.4 vs 79.1 MJ) and higher efficiency of feed conversion during 68 to 90 days of realimentation. Linear improvement (P?<?0.01) in carcass traits (preslaughter weight, empty live weight, hot carcass weight, dressing percentage, and amount of subcutaneous and intramuscular fat) and composition of longissimus dorsi muscle was observed. Ad lib concentrate supplementation for a period of 90 days may thus be considered appropriate for achieving desired efficiency of gain and improvement in body condition of cull ewes for quality mutton production. 相似文献
19.
Effect of a prolonged low-dose lipopolysaccharide infusion on feed intake and metabolism in heifers.
M Steiger M Senn G Altreuther D Werling F Sutter M Kreuzer W Langhans 《Journal of animal science》1999,77(9):2523-2532
Prolonged infusions of bacterial lipopolysaccharides (LPS) are known to model gram-negative bacterial infections, but the basic mechanisms of the LPS effects on feed intake and metabolism and their potential interdependence are largely unknown. The aim of the present study was to distinguish and to better characterize the feeding suppressive and metabolic effects of LPS. Six heifers were infused intravenously for 100 min with either 1) LPS (2 microg/kg BW) with free access to feed, 2) saline with free access to feed, or 3) saline with feeding restricted to the amount of feed consumed after LPS infusion. Feed intake, body temperature, plasma concentrations of various metabolites and hormones, and the respiratory quotient and heat production were measured. The LPS reduced feed intake and induced pronounced changes in metabolic energy turnover and fat and carbohydrate metabolism that were largely independent of the concomitant feed intake reduction. Some of the metabolic changes were biphasic; the first phase resembled a stress response with increases in plasma glucose and cortisol, and the second phase reflected a beginning energy deficit with low plasma glucose and enhanced lipolysis. The coincidence of a short-term surge of plasma insulin with marked transient decreases in plasma FFA, glycerol, and beta-hydroxybutyrate as well as with the transition from hyper- to hypoglycemia indicates that insulin plays a role in some of the metabolic responses to LPS. The failure of LPS to clearly increase energy expenditure despite the increase in body temperature suggests that anaerobic mechanisms of heat production and, perhaps, a reduced peripheral blood flow contributed to the fever. Many of the initial metabolic responses occurred before and, therefore, independent of, an increase in circulating tumor necrosis factor-alpha. 相似文献
20.
J L Sartin C Dyer R Matteri D Buxton F Buonomo M Shores J Baker J A Osborne T Braden B Steele 《Journal of animal science》2001,79(6):1573-1577
Orexin is a hypothalamic neuropeptide that regulates feeding behavior in rats. Orexin-B has recently been cloned in pigs and was shown to stimulate food intake after intramuscular injection. This study was designed to determine whether intracerebroventricular (ICV) and intravenous injections of orexin could regulate appetite in sheep. Suffolk wethers were moved to indoor facilities, adapted to diets for 6 wk, and trained to stand in stanchions for 3 to 6 h each day for 2 wk before indwelling ICV cannulas were installed. These sheep were provided water and they consumed feed ad libitum. On the day before an experiment, each sheep was cannulated in a jugular vein. On the day of an experiment, sheep were placed in stanchions and allowed to stand for 1 h before use. Sheep were then monitored over a 2-h control period before i.v. injection with saline or porcine orexin-B (3 micrograms/kg BW) or ICV injection with artificial cerebrospinal fluid (CSF), orexin (0.03, 0.3, or 3 micrograms/kg BW) or in a second experiment with either orexin B (0.03, 0.3, 3 micrograms/kg BW), neuropeptide-Y (NPY; 0.3 microgram/kg BW), or orexin plus NPY. Food intake was monitored for consecutive 2-h periods. The i.v. injections of orexin did not affect food intake or metabolite or hormone concentrations. In ICV sheep, orexin increased food intake at 2 (P < 0.04) and at 4 h (P < 0.02). Food intake was greatest with the 0.3 microgram/kg BW dosage of orexin (P < 0.05). In the first 2 h after injection, orexin had an effect similar to that of NPY (0.23 kg for orexin and 0.2 kg for NPY). The combination of NPY and orexin had a greater effect on food intake (to 0.34 kg) than did either orexin (P < 0.05) or NPY (P < 0.008) alone. Differences were not apparent in the subsequent 2-h interval. No differences were noted in free fatty acid, glucose, growth hormone, luteinizing hormone, or insulin concentrations following orexin injection. There was an effect of ICV orexin treatment on plasma cortisol concentrations (P < 0.002). Cortisol was increased by orexin at the 0- to 2-h (P < 0.008) and in the 2- to 4-h (P < 0.009) intervals after orexin injection. These data indicate that central administration of orexin stimulates feed intake in sheep. 相似文献