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1.
OBJECTIVE: To determine whether a shoe with an axialcontoured lateral branch would induce greater lateral roll of the forelimb hoof during the time between heel and toe lift-off at end of the stance phase (breakover). Animals-10 adult horses. PROCEDURE: A gyroscopic transducer was placed on the hoof of the right forelimb and connected to a transmitter. Data on hoof angular velocity were collected as each horse walked and trotted on a treadmill before (treatment 1, no trim-no shoe) and after 2 treatments by a farrier (treatment 2, trim-standard shoe; and treatment 3, trim-contoured shoe). Data were converted to hoof angles by mathematical integration. Breakover duration was divided into 4 segments, and hoof angles in 3 planes (pitch, roll, and yaw) were calculated at the end of each segment. Multivariable ANOVA was performed to detect differences among treatments and gaits. RESULTS: Trimming and shoeing with a shoe with contoured lateral branches induced greater mean lateral roll to the hoof of 3.2 degrees and 2.5 degrees during the first half of breakover when trotting, compared with values for no trim-no shoe and trim-standard shoe, respectively. This effect dissipated during the second half of breakover. When horses walked, lateral roll during breakover was not significantly enhanced by use of this shoe. CONCLUSIONS AND CLINICAL RELEVANCE: A shoe with an axial-contoured lateral branch induced greater lateral roll during breakover in trotting horses, but change in orientation of the hoof was small and limited to the first half of breakover.  相似文献   

2.
Various farriery methods have been described for treating chronic laminitis, yet no particular method has become the preferred choice. The wooden shoe may possess certain advantages such as redistributing load evenly over the palmar/plantar section of the foot due to its flat solid construction and the mechanics (bevelled perimeter, breakover and heel elevation) that can be incorporated directly into the fabrication of the shoe. It should be apparent that the advantages of this farriery option will also be limited unless strict attention is paid to the details involving radiology, foot preparation and alignment of the distal phalanx within the hoof capsule.  相似文献   

3.
Point of breakover, defined as the portion of the hoof last in contact with the ground during the terminal stance phase of a limb, can be influenced by many factors including craniocaudal placement of the shoe. Shortening the point of breakover has been suggested to decrease strain on the deep digital flexor tendon and navicular bone as well as to improve the alignment of the second and third phalanx. The current experiment involved eight sound horses fitted with aluminum plates adhered to their front hooves, which were drilled and tapped to allow additional aluminum plates of various lengths to be attached (the longest plate was placed flush with the toe, while the shortest plate was moved 3.81 cm caudal to the toe). Horses were recorded on video while at the walk and trot over a distance of 70 meters for six repetitions to determine differences in gait kinematics. Results of this study show significant changes in stride kinematics caused by shortening the point of breakover. Retraction of the forelimbs was greatest when breakover was moved 1.27 cm back from the toe (P < .05), and minimum height of the fetlock at the trot was higher on all treatments where the breakover point was moved caudally (P < .05). Some improvements in gait quality were observed when breakover was shortened, although extreme caudal placement of the shoe (negative placement in relation to P3) resulted in a decrease in gait quality as seen by decreased retraction of the forelimb (P < .05) coupled with hoof height occurring earlier in the stride (P < .05).  相似文献   

4.
The wooden shoe provides the clinician with an alternative option to conventional farriery when treating a variety of foot problems such as acute/chronic laminitis, white line disease, distal phalanx fractures and poor-quality hoof capsules. The wooden shoe provides a simplified method to apply many of the principles of therapeutic farriery which include redistributing the load or forces on the foot, repositioning breakover and providing heel elevation when necessary. Understanding the biomechanics of the wooden shoe along with understanding good basic farriery which include the appropriate foot trim, proper size, fit and placement of the wooden shoe on the foot combined with the appropriate application are essential for consistent success. This paper outlines what is considered to be the proper application of the wooden shoe.  相似文献   

5.
AIM: To quantify the effect of plain, wedged and eggbar shoes on the distribution of pressure under the hoof of horses at the walk, at selected areas of interest (AOI), to find scientific evidence for the perceived efficacy of these shoes in the treatment of palmar heel pain. METHODS: Six clinically sound adult Warmblood mares weighing 551 (SD 25) kg were shod (forelegs) with either plain, eggbar or 6 degrees-wedge shoes using a latin-square experimental design. All horses were shod by the same farrier, and each balanced and aligned for its individual conformation. Data were collected on three walking strides for each foreleg using a 550 x 405-mm pressure plate to quantify the distribution of pressure under each type of shoe at five AOI. RESULTS: Landing of the hoof with all three shoes was predominantly from lateral to medial (range 7-15 msec). Irrespective of the type of shoe, the greatest pressure was found in the lateral and medial toe (lateral 39.7 (SE 0.6) N/cm2 and medial 35.0 (SE 0.5) N/cm2) and the point of the toe (33.3 (SE 0.5) N/cm2). The lowest peak pressure was in the heel (lateral 25.9 (SE 0.5) N/cm2 and medial 21.1 (SE 0.4) N/cm2; p<0.05). Eggbar and wedge shoes increased total stance time (938 (SE 8) msec and 952 (SE 6) msec, respectively) compared with plain shoes (898 (SE 14) msec) (p<0.05). The wedge shoe reduced breakover compared with the plain and eggbar shoes (13.8% vs 15.8% and 14.5%, respectively; p<0.05). The eggbar shoe had lower total shoe peak pressure (29.5 (SE 0.7) N/cm2) than plain (31.8 (SE 0.5) N/cm2) and wedge (30.9 (SE 0.6) N/cm2) shoes. CONCLUSIONS AND CLINICAL RELEVANCE: Both the eggbar and 6 degrees-wedge shoe offer advantages for palmar heel pain. In comparison to the plain shoe, the eggbar shoe had less peak pressure at the heel AOI, and across the entire shoe, due to the greater bearing surface and the effect of the longer heel. The 6 degrees-wedge shoe had greater loading on the lateral heel AOI, but promoted earlier breakover at the toe. Both shoes offer advantages for the horse with palmar heel pain, though choice of shoe will depend on clear identification of the causative factors, to provide therapeutic shoeing that maximises the individual horse's response.  相似文献   

6.
Every equine hoof has a certain amount of distortion. This presents in various forms: flares, dished toes, under-run heels, and cracks. Several farrier texts anecdotally suggest a correlation between hoof capsule distortion and lameness. The goal of this study was to evaluate the effects of the Sigafoos Series I glue-on shoe on hoof capsule distortion, and specifically, the effect on dorsal wall deviation. Measurements of the hoof were made using the Metron hoof evaluating system by Eponatech. Comparisons were made of the following values: dorsal length, hoof angle, dorsal wall deviation, hairline angle, hairline deviation, heel/toe height, heel height, heel angle, and support length. The study group consisted of front feet of horses shod exclusively in the Sigafoos glue-on shoe for a period of 1 year, and the control group consisted of 133 front feet from horses using nailed on shoes for a similar period and with a musculoskeletal complaint. The results indicate a 48% reduction in dorsal wall deviation for the study group. This finding supports the use of this glue-on shoe as beneficial with the goal to reduce capsular distortion of the dorsal wall.  相似文献   

7.
In a controlled experimental study, eight sound horses were shod with a plain steel shoe on one forelimb (control limb) and with four different shoe types on the other forelimb (treated limb). The four shoe types used on the treated limb were a plain steel shoe, a rocker-toe shoe, a rolled-toe shoe, and a square-toe shoe. The selection of the treatment limb (left or right) was randomized between the horses and a replicated Latin square design was used to determine the order of application of the shoes to the treatment limb. High speed cinematography (200 frames/s) was used to film the horses trotting in hand on a concrete surface. Eight strides were analyzed for each shoeing treatment. The breakover times of both forelimbs were measured, and the breakover ratio was computed as the ratio between the breakover time of the treated limb to the breakover time of the control limb. The results of an analysis of variance, using a probability of 0.05 alpha, showed that the breakover ratio did not differ significantly between the four types of shoes (p=0.10). It is concluded that, in sound horses trotting at a slow speed on a hard surface, the application of a rocker-toe shoe, a rolled-toe shoe or a square- toe shoe did not shorten forelimb breakover duration significantly compared with a plain steel shoe.  相似文献   

8.
A shoe was designed to combine the advantages of a reverse shoe and an adjustable heart bar shoe in the treatment of chronic laminitis. This reverse even frog pressure (REFP) shoe applies pressure uniformly over a large area of the frog solar surface. Pressure is applied vertically upward parallel to the solar surface of the frog and can be increased or decreased as required. Five clinically healthy horses were humanely euthanased and their dismembered forelimbs used in an in vitro study. Frog pressure was measured by strain gauges applied to the ground surface of the carrying tab portion of the shoe. A linear variable distance transducer (LVDT) was inserted into a hole drilled in the dorsal hoof wall. The LVDT measured movement of the third phalanx (P3) in a dorsopalmar plane relative to the dorsal hoof wall. The vertical component of hoof wall compression was measured by means of unidirectional strain gauges attached to the toe, quarter and heel of the medial hoof wall of each specimen. The entire limb was mounted vertically in a tensile testing machine and submitted to vertical downward compressive forces of 0 to 2,500 N at a rate of 5 cm/minute. The effects of increasing frog pressure on hoof wall weight-bearing and third phalanx movement within the hoof were determined. Each specimen was tested with the shoe under the following conditions: zero frog pressure; frog pressure used to treat clinical cases of chronic laminitis (7 N-cm); frog pressure clinically painful to the horse as determined prior to euthanasia; frog pressure just alleviating this pain. The specimens were also tested after shoe removal. Total weight-bearing on the hoof wall at zero frog pressure was used as the basis for comparison. Pain-causing and pain-alleviating frog pressures decreased total weight-bearing on the hoof wall (P < 0.05). Frog pressure of 7 N-cm had no statistically significant effect on hoof wall weight-bearing although there was a trend for it to decrease as load increased. Before loading, the pain-causing and pain-alleviating frog pressures resulted in a palmar movement of P3 relative to the dorsal hoof wall compared to the position of P3 at zero frog pressure (P < 0.05). This difference remained statistically significant up to 1300 N load. At higher loads, the position of P3 did not differ significantly for the different frog pressures applied. It is concluded that increased frogpressure using the REFP shoe decreases total hoof wall weight-bearing and causes palmar movement of P3 at low weight-bearing loads. Without a shoe the toe and quarter hoof wall compression remained more constant and less in magnitude, than with a shoe.  相似文献   

9.
The biomechanical effects of lowering and raising the heels were studied using a finite element (FE) computer model of the equine hoof capsule consisting of 18,635 finite elements. A static load of 3000 N was distributed to nodes of the inner hoof wall (80%) according to the suspension of the coffin bone, 20% loaded sole and frog. When loaded the FE hoof capsules showed the following deformations: the proximal dorsal wall moves back, the quarters flare to the side and sole and frog perform a downward movement. Stresses are high in the material surrounding the quarter nails, in the heels and in the proximal dorsal wall. Three types of horseshoes were simulated, a regular shoe with flat branches, a shoe with 5 degrees raised heels and a shoe with 5 degrees lowered heels. Raising the heels resulted in significantly (P < 0.05) low stress and displacement values. The lowered heels model calculated highest stress and displacement values and the results of the FE model with the regular horseshoe were found in between.  相似文献   

10.
OBJECTIVE: To evaluate using strain gauges, a hoof cast with heel wedge, and a therapeutic shoe with unsupported toe for their effectiveness in redistribution of load from the dorsal hoof wall. STUDY DESIGN: In vitro biomechanical study. SAMPLE POPULATION: Twenty forelimb specimens. METHODS: Rosette strain gauges were placed on the dorsal and lateral hoof wall of 20 normal shaped hooves. Limbs were loaded vertically using a tensile testing machine with a 1 Hz sinusoidally cycling load up to 3000 N during 15 seconds. Mean values of principal strain and direction at 2500 N load were calculated for 3 experimental conditions (unshod, therapeutic shoe with unsupported toe, and hoof cast with heel elevation) and tested by ANOVA (P<.05). RESULTS: Vertical limb loading in an unshod hoof leads to a biaxial compression of the dorsal wall with high longitudinal compression (epsilon2 = -1515 microm/m). Principal strain at the dorsal wall (epsilon2) was decreased by 23% with the therapeutic shoe and by 59% with the hoof cast. On the lateral hoof wall principal strain was unchanged with the shoe, but increased by 34% with the cast. CONCLUSIONS: Strain measurements indicate unloading of the dorsal hoof wall by both methods with the cast being more effective than the shoe. CLINICAL RELEVANCE: The hoof cast with wedge offers substantial unloading of the dorsal wall, but increases load on the quarter. Therefore a hoof cast would likely be most helpful in acute laminitis when palmar structures can still bear load. The therapeutic shoe offers rehabilitation and regrowth of the dorsal wall without increased load on the quarter wall.  相似文献   

11.
OBJECTIVE: To determine the mechanism that enables horses to partially counteract the shift of the center of pressure under the hoof induced by changes in hoof morphology attributable to growth and wear during a shoeing interval. ANIMALS: 18 clinically sound Warmblood horses. PROCEDURES: Horses were evaluated 2 days and 8 weeks after shoeing during trotting on a track containing pressure-force measuring plates and by use of a synchronous infrared gait analysis system set at a frequency of 240 Hz. All feet were trimmed toward straight alignment of the proximal, middle, and distal phalanges and shod with standard flat shoes. Results-Temporal characteristics such as stance time and the time between heel lift and toe off (ie, breakover duration) did not change significantly as a result of shoeing interval. Protraction and retraction angles of the limbs did not change. Compensation was achieved through an increase in the dorsal angle of the metacarpohalangeal or metarsophalangeal (fetlock) joint and a concomitant decrease of the dorsal angle of the hoof wall and fetlock. There was an additional compensatory mechanism in the hind limbs during the landing phase. CONCLUSIONS AND CLINICAL RELEVANCE: Horses compensate for changes in hoof morphology that develop during an 8-week shoeing interval such that they are able to maintain their neuromuscular pattern of movement. The compensation consists of slight alterations in the angles between the distal segments of the limb. Insight into natural compensation mechanisms for hoof imbalance will aid in the understanding and treatment of pathologic conditions in horses.  相似文献   

12.
The term Eponychium is used to describe the deciduous hoof capsule in veterinary-medical and embryological literature. In other aspects of veterinary medicine, the term is generally reserved for the perioplic corium of the permanent hoof. In order to clarify this double usage, the structure and origin of the hoof epidermis from 10 equine fetus at different stages of development and 4 newborn foals were investigated and described using light microscopical techniques. Epidermal tubules and lamellae are already present in the non-cornified fetal hoof epidermis. These structures, along with the formation of a white line, allow this epidermis to be divided into the same segments as are commonly used when referring to the permanent hoof. The greatest part of the deciduous hoof epidermis consists of the sole and frog, with significant portions forming in the coronary corium and that of the hoof wall as well. The perioplic corium only makes up insignificant portions of the fetal hoof capsule, however. Between the second half of the gestation period and birth, this deciduous (primary) hoof capsule is continually being replaced from below by newly-forming, cornified permanent hoof capsule. On the basis of its structure and origin, we therefore suggest that the term "deciduous hoof capsule (Capsula ungulae decidua)" be used as a replacement for the word "Eponychium" when referring to the primary hoof epidermis.  相似文献   

13.
Orthopaedic shoeing applied for disorders such as navicular disease is mostly evaluated on hard track surfaces, but very often horses are ridden only on soft tracks. To compare the effects of normal shoes, eggbar shoes, and shoes with heel wedges (5 degrees) on the kinematics of the distal forelimb on hard and soft track surfaces, eleven sound Dutch Warmblood horses were led across three different tracks (an asphalt, a fibre/sand mix (= Agterberg), and a pure sand track) with three different shoe types (a normal shoe, an eggbar shoe, and a shoe with heel wedges). The hoof rotation and the maximal extension of the fetlock joint at midstance period were recorded by an infrared-light based gait analysis system (ProReflex) at walk and at trot. Statistical analysis revealed significant effects of track and shoe type, and a shoe-track interaction (p<0.05). On soft track surfaces, the equilibrium of the distal forelimb dictated a 1.5-4 degrees forward rotation of the normal or eggbar shod foot, the most on a sand track. The wedge effect on hoof rotation, however, was always significantly greater, but similar to that on the hard track surface (5 degrees forward rotation). The maximal fetlock extension was less on a soft surface, in particular on the sand track (p<0.05). This decrease was most pronounced when the horses were shod with heel wedges and was least pronounced with normal shoes. In conclusion, in particular the sand track allows a forward rotation of the hoof and thus relief of pressure in the navicular area, and a decrease in maximal fetlock extension and thus unloading of the fetlock joint. The extra forward rotation of the hoof induced by heel wedges on hard tracks was almost the same on soft track surfaces. Eggbars and fibre/sand mix tracks have intermediate effects on unloading of the distal forelimb.  相似文献   

14.
REASONS FOR PERFORMING STUDY: Overload injuries in sport horses commonly occur; shoeing techniques are believed to be important in prevention of these injuries, but there is a paucity of scientific information identifying the potential connection. OBJECTIVES: To test a horseshoe with a modified rolled toe designed to ease the process of breakover and decrease loading of lesion-prone structures of the distal limb. METHODS: Twenty clinically sound Warmblood horses trotted over a track containing a pressure/force measuring system and 6 infrared cameras. The horses were measured with 2 types of shoes, standard flat shoes and shoes with a rolled toe. The shoeing procedure was randomised and horses had 2 days between measurements to adapt to the shoes. RESULTS: Limb placement and timing characteristics, e.g. breakover duration, did not change significantly. There was an improvement in the ease of movement to roll over the toe in the shoes with a rolled toe, due mainly to a smoother hoof-unrollment pattern. The peak indicative moment decreased substantially at the onset of breakover in the shoe with the rolled toe. CONCLUSIONS: With a rolled toe the process of hoof-unrollment is smoother, which improves the coordination of this process, and lowers peak loading of the distal limb during breakover. POTENTIAL RELEVANCE: This study stresses the importance of proper shoeing in sound horses, showing that shoe modifications can optimise the loading characteristics of the distal limb and therefore might be a means to prevent sport horses from overload injuries.  相似文献   

15.
A heel extension shoe was used as an adjunct to primary tendon repair in a dairy cow. A shoe was placed on the foot for 6 weeks after the foot had been immobilized for 6 weeks in a cast. The shoe was continuous across the toes to provide even support for both claws and was nailed and clinched in the same way a shoe is applied to a horse's hoof. Special adaptations included drilling nail holes closer to the rim of the shoe to accommodate the narrower bovine hoof wall. The cow was permitted controlled exercise for gradual remodeling and strengthening of the tendon repair. When the shoe was removed 12 weeks after surgery, the metatarsophalangeal and distal interphalangeal joints were in normal posture. We consider application of a therapeutic shoe to be an important adjunct to surgical repair of major tendon injuries in adult cattle.  相似文献   

16.
REASONS FOR PERFORMING STUDY: As critical locomotion events (e.g. high-speed and impacts during racing, jump landing) may contribute to tendinopathies, in vivo recording of gaits kinematic and dynamic parameters is essential for 3D reconstruction and analysis. OBJECTIVE: To propose a 3D model of the forelimb and a ground reaction force recording shoe (GRF-S) for noninvasively quantifying tendon and ligament loads and strains. METHODS: Bony segments trajectories of forelimbs placed under a power press were recorded using triads of ultrasonic kinematic markers linked to the bones. Compression cycles (from 500-6000 N) were applied for different hoof orientations. Locations of tendon and ligament insertions were recorded with regard to the triads. The GRF-S recorded GRF over the hoof wall and used four 3-axis force sensors sandwiched between a support shoe and the shoe to be tested. RESULTS: Validation of the model by comparing calculated and measured superficial digital flexor tendon strains, and evaluation of the role of proximal interphalangeal joint in straight sesamoidean ligament and oblique sesamoidean ligament strains, were successfully achieved. Objective comparisons of the 3 components of GRF over the hoof for soft and hard grounds could be recorded, where the s.d. of GRF norm was more important on hard ground at walk and trot. CONCLUSIONS: Soft grounds (sand and rubber) dissipate energy by lowering GRF amplitude and diminish bounces and vibrations at impact. At comparable speed, stance phase was longer on soft sand ground. POTENTIAL RELEVANCE: The conjugate use of the GRF-S and the numerical model would help to quantify and analyse ground/shoe combination on comfort, propulsion efficiency or lameness recovery.  相似文献   

17.
This study assesses the biomechanical effects on the phalangeal alignment, the pressure force distribution, and the footing pattern on different grounds created by different horseshoes modified in the dorsopalmar surface. Twenty-five warmblood horses were divided into five groups (n = 5). In each group, radiographic and kinetic examinations were carried out for each barefoot hoof, standard, and modified horseshoe. For radiographic measurements, a modified podoblock, simulating firm and penetrable ground, was used. For kinetic examinations, hoof and horseshoe were simultaneously equipped with sensor foils and horses were walked on different grounds (concrete, rubber, firm, and deep sand). None of the horseshoes showed an effect on the bone alignment on firm ground. On penetrable ground, the bar shoes caused a steeper palmar angle (P3), whereas with a wide toe shoe, a flatter orientation of the distal phalanx was observable. The influence on the alignment of the middle and proximal phalanx showed no constant data. On penetrable ground, pressure peaks occurred at the heels after the application of bar shoes. Moreover, pressure peaks were observable beneath the ends of the branches of the open toe shoe, and the toe and thin branches of the wide toe shoe. The footing pattern was only affected by the open toe shoe. In conclusion, the biomechanical effects of the examined modified horseshoes are mainly influenced by different ground conditions. Moreover, unintended side effects such as unexpected pressure peaks or an enhanced mediolateral sink in of the hoof occur in addition to the required impacts during a therapeutical treatment.  相似文献   

18.
Reasons for performing study: In the treatment of laminitis it is believed that reducing tension in the deep digital flexor tendon by raising the palmar angle of the hoof can reduce the load on the dorsal lamellae, allowing them to heal or prevent further damage. Objective: To determine the effect of alterations in hoof angle on the load in the dorsal laminar junction. Methods: Biomechanical finite element models of equine hooves were created with palmar angles of the distal phalanx varying from 0–15°. Tissue material relations accounting for anisotropy and the effect of moisture were used. Loading conditions simulating the stages in the stance where the vertical ground reaction force, midstance joint moment and breakover joint moment were maximal, were applied to the models. The loads were adjusted to account for the reduction in joint moment caused by increasing the palmar angle. Models were compared using the stored elastic energy, an indication of load, which was sampled in the dorsal laminar junction. Results: For all loading cases, increasing the palmar angle increased the stored elastic energy in the dorsal laminar junction. The stored elastic energy near the proximal laminar junction border for a palmar angle of 15° was between 1.3 and 3.8 times that for a palmar angle of 0°. Stored elastic energy at the distal laminar junction border was small in all cases. For the breakover case, stored elastic energy at the proximal border also increased with increasing palmar angle. Conclusions and potential relevance: The models in this study predict that raising the palmar angle increases the load on the dorsal laminar junction. Therefore, hoof care interventions that raise the palmar angle in order to reduce the dorsal lamellae load may not achieve this outcome. See also correspondence by Redden See also correspondence by Curtis  相似文献   

19.
An 8-year-old Thoroughbred gelding presented with chronic intermittent lameness of the left forelimb. Keratoma was diagnosed based on history, clinical signs and the radiographic evidence of a radiolucent concavity of the third phalanx. The keratoma was removed by hoof wall resection and the foot was immobilized using a bar shoe with clips and a dorsal hoof wall plate positioned across the hoof wall defect. The hoof wall defect was completely filled with new hoof wall by 9 months postoperatively. The horse returned to normal athletic function and is performing successfully 18 months later.  相似文献   

20.
The aim of this study was to describe the microstructure of the pigmented and depigmented hoof capsule of Girolando cattle by bi‐ and tridimensional microtomography and nanoindentation, analysing the possible relation between these findings and the susceptibility of such animals to podal diseases. To carry out the microtomography and the nanoindentation, duplicated samples were collected from the dorsal wall, abaxial wall and pre‐bulbar sole of the hoof capsule. Material collection was performed in 40 medial digits of thoracic limbs and 40 lateral digits of pelvic limbs. The bidimensional microtomography showed that the dorsal wall of the thoracic and pelvic limbs presented higher density, followed by the abaxial wall, and finally by the sole, with the lowest density. Moreover, the hoof capsule of cows of Girolando breed is a compact, non‐porous material, and constituted by extratubular and intratubular keratin. By the tridimensional microtomography, it was possible to measure the angles of the corneal tubules in relation to the periople and the claws in the different regions of the hoof capsule, which were 90° for the dorsal wall, 55° for the abaxial wall and 70° for the sole. The tridimensional microtomography also showed corneal tubules of different diameters: 17, 51, 85, 119 and 153 μm. The nanoindentation test, when performed in different regions of the hoof capsule, did not reveal significant difference of Vickers hardness in the evaluated areas. However, we verified a larger elastic module of these regions on the transversal cut of the corneal tubules compared to the longitudinal cut.  相似文献   

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