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1.
During the summer and fall of 1987, sows from eight herds in three states were assigned randomly to receive either a combination of 400 IU of pregnant mare's serum gonadotropin with 200 IU of hCG (P.G. 600) or no treatment at weaning. A treatment x parity interaction was observed for days to first estrus after treatment and percentage anestrus (percentage of sows not achieving estrus within 10 d after weaning). Relative to primiparous control sows, primiparous sows given P.G. 600 expressed estrus sooner (P less than .02) after weaning (6.0 vs 7.8 +/- .6 d) and exhibited less (P less than .02) postweaning anestrus (15.6 vs 29.2 +/- 4.0%). Second parity sows that received P.G. 600 showed estrus sooner (P less than .06) than second-parity control sows (4.7 vs 6.4 +/- .7 d). Days to first estrus after treatment did not differ between groups for parity-three and older sows, and percentage anestrus was not different between treatments for parity-two and older sows. The herd X treatment interaction was significant for percentage recycled (percentage of successfully mated sows that returned to estrus), subsequent farrowing rate, and subsequent number of pigs born dead. Number of pigs born alive was lower for sows treated with P.G. 600 than for control sows (10.55 vs 10.10 +/- .18; P less than .02). In summary, treatment of sows weaned in the summer and fall with P.G. 600 had decreased days to postweaning estrus in parity-one and -two sows and reduced frequency of postweaning anestrus in primiparous sows.  相似文献   

2.
The aim of the study was to investigate the prevalence of Actinobacillus pleuropneumoniae infections in market weight pigs in Thailand. ELISA systems employing purified lipopolysaccharide antigens were used to detect antibodies in 549 serum samples collected from pigs of 22 herds. Relevant cut-off values were established from three herds defined seronegative. Serum antibodies were detected to all serotypes except serotype 10. Almost 60% of the samples were seropositive to at least one serotype and 45% of the pigs were seropositive to more than one serotype. Antibodies to the cross-reacting serotypes 1, 9 or 11 were found in 29% of the pigs. Other common serotypes included the cross-reacting serotypes 3, 6 or 8 (26% seropositive pigs) and serotype 5a (also 26%). Antibodies to serotypes 2, 5b and 12 were low in prevalence (<10%). Three herds were regarded to be seronegative and six to have a low pathogen load with respect to the prevalence of seropositive pigs. The remaining 13 herds had a high incidence of pigs with antibodies to A. pleuropneumoniae, dominated by serotypes 1-9-11 and 5a (n = 6), serotypes 3-6-8, and 5a (n = 4) or 1-9-11, 3-6-8, 5a and 4-7 (n = 3). A low pathogen load with respect to A. pleuropneumoniae, as well as small herd size and age-segregated rearing, tended to improve the performance of growers.  相似文献   

3.
One hundred 3/4 Duroc-1/4 Landrace (DDL), 3/4 Hampshire-1/4 Landrace (HHL) and 3/4 Spot-1/4 Landrace (SSL) backcross sows were randomly mated to Yorkshire boars to produce a total of 299 litters and 3,271 pigs to determine the effect of dam breeding on preweaning and postweaning performance of the pigs and litters. Litter sizes born and born alive were not significantly different among the three dam breeds studied. However, litter sizes alive at 21 d out of HHL sows were significantly larger than litter sizes out of SSL sows, while the litter sizes out of DDL sows were intermediate to the other two dam breeds. The DDL sows had significantly heavier litters at birth than did SSL sows, but the dam breeds did not differ in the weights of their litters at 21 and 42 d. Pigs out of DDL sows were heaviest at birth but weighed the least at 21 d, while pigs out of SSL sows were heaviest at 21 and 42 d of age. Pigs out of HHL sows weighed the least at birth and at 42 d. There were no significant differences among the dam breeds in the survival rate of their pigs. In the postweaning period, pigs out of HHL sows were the slowest growing and took the most days to reach 100 kg. Feed conversion and average daily feed consumption did not differ significantly among the three dam breeds studied.  相似文献   

4.
One hundred thirty Yorkshire-Landrace (YL), Chester White-Landrace (CL) and Chester White-Yorkshire (CY) F1 crossbred sows were mated randomly to Duroc (D), Hampshire (H), Farmers Hybrid 414 (FH414) or Farmers Hybrid 929 (FH929) boars. These matings produced 321 litters and 3,379 pigs, which were used to determine the effect of sire breeding and dam breeding on preweaning and postweaning performance of the pigs and litters. Litter size born alive, litter size at 56 d, litter weight at 56 d and litter weight per day of age to 100 kg were lower in litters sired by H boars than in those sired by D boars. However, sizes and weights of litters sired by D and H boars were not different from those sired by FH414 and FH929 boars. Litter sizes at birth were larger for litters out of CL and CY sows than those out of YL sows, but significant differences were not found for litter sizes at 21 d, 56 d or at marketing. Pigs sired by H boars were heavier at birth than pigs sired by D boars. Pigs sired by H boars did not differ significantly in weights at 21 and 56 d or in postweaning daily gains or days to 100 kg from pigs sired by D boars. Pigs out of CL dams were heavier at birth, 21 d and 56 d of age than pigs out of CY dams, but did not differ significantly in postweaning gains or in days to 100 kg. Pigs sired by D and H boars had less ultrasonic fat than pigs sired by FH414 and FH929 boars. Pigs sired by FH929 boars were leaner than pigs sired by FH414 boars.(ABSTRACT TRUNCATED AT 250 WORDS)  相似文献   

5.
Between September 1982 and March 1984, 101 Western Australian piggeries with 15 or more sows were surveyed to determine the prevalence of internal parasites and examine the relationship between parasitism and management practices. Faecal samples were collected from 20 pigs in 4 age groups in randomly selected piggeries, and examined for the presence of eggs of helminth parasites and protozoan cysts. Evidence of nematode parasites was found in 79% of piggeries. Sows were more commonly affected than other classes of pigs with worm eggs being found in 68% of herds. Oesophagostomum spp was the most prevalent worm species, being found in pigs from 65% of piggeries and in sows in 60% of herds. Ascaris suum was the most common species of worm found in growing pigs. There was no evidence of infection with either Metastrongylus spp or Strongyloides spp in any of the herds sampled. Oocysts of coccidia were found in pigs from 56% of piggeries and Balantidium coli cysts were detected in pigs from 42% of piggeries sampled.  相似文献   

6.
The objectives of this study were to elucidate at which age tonsillar colonisation by Actinobacillus pleuropneumoniae occurs in pigs and relate this occurrence to the presence of colostral antibodies to A. pleuropneumoniae. The infection patterns were studied in an isolated cohort of pigs, which consisted of the offspring from five sows originating from a conventional pig herd. The sows were transferred to isolated research facilities before farrowing. A. pleuropneumoniae was detected on the tonsils of all sows. After a nursing period of 3 weeks, the pigs were weaned and reared isolated from other pigs until slaughter. The pigs were examined repeatedly for the presence of A. pleuropneumoniae on the tonsils and for antibodies to A. pleuropneumoniae using bacteriological and serological techniques, respectively.A. pleuropneumoniae was detected in the tonsils of one pig as early as 11 days after birth, showing that A. pleuropneumoniae can be transmitted from sow to offspring during a 3-week nursing period. The cumulative proportion of pigs carrying A. pleuropneumoniae in their tonsils increased significantly between the age of 4-12 weeks. This age period corresponded to the age at which the proportion of pigs with detectable levels of colostral antibodies to the different serotypes of A. pleuropneumoniae was declining. Since these two events take place in the same age period, we expect a possible biological association between the level of the passive immunity and the degree of tonsillar colonisation. The median duration of tonsillar colonisation was estimated to approximately 7-8 weeks.  相似文献   

7.
The main objective of this study was to estimate the decay of acquired colostral antibodies to Actinobacillus pleuropneumoniae serotype 2 in pigs. Data were obtained from pigs in an isolated cohort of 47 pigs born to five sows seropositive to A. pleuropneumoniae serotype 2. The pigs were examined serologically at 18 different times from birth until an age of about 22 weeks, using an A. pleuropneumoniae serotype 2-specific blocking enzyme-linked immunosorbent assay. Antibody concentration was expressed as an OD% derived from the optical density of the sample and the median from eight wells without serum on the same plate. A non-linear mixed model assuming a constant rate of decay (half-life) was specified and fitted to the serological data. To estimate the between-pig variability of different components, between-pig random effects of each component of the model were estimated. The estimated average half-life of acquired colostral antibodies was approximately 2 weeks, but there was a considerable variation between pigs (half-life ranged from 1-3 weeks). The duration until acquired colostral antibodies were no longer detectable ranged from 2 weeks to 2 months postpartum among the pigs in the study, mainly depending on the initial level of acquired colostral antibodies to A. pleuropneumoniae serotype 2.  相似文献   

8.
9.
Many farrow-to-finish herds are endemically infected with Actinobacillus pleuropneumoniae. In order to control the disease efficiently, a better knowledge of the ages at which pigs become infected is necessary. Furthermore, no information is available concerning the influence of maternally derived antibodies on the colonization of the upper respiratory tract. Therefore, A. pleuropneumoniae infection patterns were studied in five farrow-to-finish pig herds (A-E) with a history of pleuropneumonia. A longitudinal study was carried out in herds A and B. In these herds, piglets from sows carrying A. pleuropneumoniae in their noses or tonsils were sampled. Nasal and tonsillar swabs as well as sera, were collected from these animals at the age of 4, 8, 12, 16 (herds A and B) and 23 weeks (herd B). At these ages other pigs from the same sows were euthanized. The lungs were macroscopically examined and samples from nose, tonsils and lungs were collected at necropsy. A cross-sectional study was performed in herds C-E. In these herds nasal and tonsillar swabs, as well as sera, were taken from 10 animals of 4, 8, 12 and 16 weeks of age. Lung, nasal and tonsillar samples were tested for the presence of A. pleuropneumoniae by routine bacteriology and PCR with mixed bacterial cultures. The sera were examined for the presence of Apx toxin neutralizing antibodies. In herd A, A. pleuropneumoniae serotype 2 and 10 strains were isolated, whereas serotype 2, 3, 5b and 8 strains were demonstrated in herd B. In most herds, A. pleuropneumoniae was detected in mixed bacterial cultures of tonsillar and/or nasal samples by PCR from the age of 4 weeks onwards. Colonization of the lungs and development of lung lesions was observed in 12- and 16-week-old animals of herd A and 23-week-old animals of herd B. In most herds, high antibody titres were detected in 4-week-old piglets. These titres decreased during the first 12 weeks of age, but thereafter, increased. It was concluded that PCR with mixed bacterial cultures from tonsillar swabs is a valuable tool for the detection of infected animals. It was also concluded that colonization of tonsils and nasal mucosae can occur in the presence of maternally derived antibodies. Infection of the upper respiratory tract without lung involvement did not result in development of Apx toxin neutralizing antibodies. Therefore, such serological assays cannot be used for the detection of subclinically infected animals.  相似文献   

10.
Three trials involving 118 sows were conducted to evaluate the effects of fat and triamcinolone additions in the diets of late-term gravid sows on pre- and postweaning performance of pigs. Beginning an average of 9 d prepartum, sows were fed daily 1.8 kg of a fortified, corn-soybean meal diet [6 Mcal of metabolizable energy (ME) and 290 g of protein/sow] that was supplemented with 4 Mcal of ME/sow in the form of starch, soybean oil or soybean oil plus 70 mg/sow of triamcinolone, a synthetic glucocorticoid. During a 28-d lactation, sows were self-fed a standard 14% protein, corn-soybean meal diet. The addition of soybean oil to the diet of sows during late gestation did not (P greater than .10) influence the weights of survivability of pigs at birth, 14 or 28 d of age, but increased (P less than .05) the carcass fat content of the pigs at birth. The dietary addition of triamcinolone to the sow's prepartum diet increased (P less than .10) pig weights at birth and 14 d, and tended to increase pig weights at 28 d compared with those of pigs from sows fed soybean oil only. Prepartal administration of triamcinolone depressed (P less than .05) carcass protein content and adrenal weights in pigs at birth or 28 d of age. From weaning (d 28) to 56 d of age, pigs from sows fed soybean oil before parturition, particularly those from sows fed triamcinolone, tended to consume less feed and gained slower and less efficiently than pigs from sows fed starch, although the differences were not significant.(ABSTRACT TRUNCATED AT 250 WORDS)  相似文献   

11.
An epidemiological study of porcine reproductive and respiratory syndrome (PRRS) within pig herds was conducted in 8 intensive farrow-to-finish pig farms. Persistence of PRRS virus (PRRSV) in pig herds was demonstrated by regular postmortem examination on 2 farms for a period of 2 y. Virus isolation and serum neutralization (SN) tests were performed on the sera collected from 9 groups of pigs (10 pigs/group) of various ages on 8 pig farms. Except for 1 farm, isolation rates of PRRSV reached the highest level of 70 to 100% of pigs 6 to 8 wk of age, which coincided with the lowest levels of maternal immunity. In 1 pig herd, sows (39 in total) with SN titers of < or = 1:2, 1:4-1:8, and > or = 1:16 were designated as groups 1, 2, and 3, respectively. Sera were obtained from their progeny (3 pigs randomly selected from each litter) at various ages from 0 to 22 weeks. A positive correlation (r = 0.377, P < 0.001) between the SN titers of sows and those of their progeny (1-week-old piglets) was observed. Pigs at the age of 6 wk, only 7.9% of group 1 pigs compared to 72.4% of group 3 pigs were seropositive. A significant difference (P < 0.01) in the percentage of pigs with PRRSV viremia among the 3 groups was observed, with the lowest level found in group 3 pigs. The isolation rates of PRRSV from serum reached the maximum at the age of 9 wk for all 3 groups. The results indicated that passively acquired serum antibodies conferred a protective effect for piglets; however, loss of passive immunity at various ages of pigs produced susceptible pigs that resulted in PRRSV persistence in the pig herds. Pigs 6 to 9 weeks old were the major reservoir for PRRSV in farrow-to-finish pig herds.  相似文献   

12.
The aim of the present study was to explore the usefulness of serological methods in the diagnosis of postweaning multisystemic wasting syndrome (PMWS). The study was carried out in 4 PMWS-affected and 6 control farms. Based on the serological profiles, infection with porcine circovirus type 2 (PCV2) was determined to take place at 3-7 weeks of age in the PMWS-affected and at 3-11 weeks of age in the control farms. To compare the dynamics of seroconversion to PCV2 among farms, cross-sectional serological profiles were normalised in relation to the inferred age of infection. The results indicated that the proportion of seropositive pigs increased significantly slower in the affected herds. The most pronounced difference was observed about 4 weeks after infection, when the proportion of seropositive pigs ranged from 0 to 53.3% and from 70 to 100% in PMWS-affected and control herds, respectively. Mean antibody titres at that age were also significantly lower in the affected farms. These observations suggest a delay in the production of PCV2-specific antibodies and indicate that serological methods may be helpful in identifying herds with a high risk of PMWS.  相似文献   

13.
A case-control study to investigate the contribution of postweaning multisystemic wasting syndrome (PMWS) and Porcine circovirus type 2 (PCV-2) to deaths among piglets of nursery age (19 to 68 d) in Manitoba indicated a significant positive association between PCV-2 infection and an increased mortality rate in nursery pigs. The clinical syndrome PMWS was seldom recognized in case or control herds; however, PCV-2 infection was widespread at the herd level. Other factors more strongly associated with increased piglet mortality rate than herd level PCV-2 infection were Mycoplasma hyopneumonia infection, porcine reproductive and respiratory syndrome (PRRS), and diarrhea caused by Eschericia coli K88. Management factors associated with case herd status included close proximity to other herds, larger number of sows supplying pigs to the nursery, larger range in age and weight going into the nursery, the moving of lightweight pigs into another nursery room at the end of the nursery fill, and not using spray-dried plasma in the 1st nursery ration. These results highlight the host-agent-environment triad leading to high nursery-barn mortality rates.  相似文献   

14.
The present investigation comprised six integrated herds (100-150 sows each) and one specialized fattening herd. Serologic tests by ELISA were performed on blood samples from piglets and growing pigs during various rearing phases in order to determine the presence of Actinobacillus infection and to estimate the age of the animals at onset of the disease. Using this information, herd-specific vaccination programs were designed against Actinobacillus pleuropneumoniae serotype 2. The weaned piglets in the integrated herds were vaccinated twice before being moved to the fattening unit. In the specialized fattening herd, the pigs were vaccinated on arrival at the growing unit and just before transfer to the finishing unit. The frequencies of chronic pleuritis at slaughter demonstrated that a vaccination program adapted to the herd-specific problem, in combination with environmental improvements, reduces the prevalence of chronic pleuritis. On the other hand, only a moderate reduction of the prevalence of chronic pleuritis occurred as a result of vaccination if no environmental improvements were made. In two of the herds during the vaccination period, the number of feeding days and food consumption decreased, while growth per day increased. There was also an apparent correlation between higher serum titres and a decreased prevalence of pleuritis at slaughter in three of the herds.  相似文献   

15.
The relationship between the extent of seropositivity for Aujeszky's disease virus (ADV), Actinobacillus pleuropneumoniae (App.) serotype 2 and porcine influenza (PI) viruses serotype H1N1 and H3N2 in pigs on the one hand and the health status of the pigs and some farm and management conditions in the herds on the other hand was studied in 45 pig finishing herds, all members of one integration group. The health status was assessed by the extent of clinical signs, the use of veterinary drugs and the prevalence of pathological lesions in pigs at slaughter. There was no relationship between the extent of seropositivity on the one hand and clinical signs and use of veterinary drugs on the other hand. However, there was a positive relationship between the extent of seropositivity and the percentage of pigs with lesions of the respiratory tract at slaughter. Furthermore, the study indicates that the variation in seropositivity between pigs herds is associated with management related factors that particularly influence the possibility of the spreading of viruses. A sero-epidemiological investigation in 14 pig herds with recurrent pneumonia problems revealed a high percentage of seropositive pigs per herd. Furthermore, in a large number of herds, pigs were simultaneously seropositive for ADV and App. serotype 2, for ADV and PI serotype H1N1 or for ADV and PI serotype H3N2.  相似文献   

16.
Serological responses to Actinobacillus pleuropneumoniae serovar 7 infection were monitored by enzyme-linked immunosorbent assay in a cohort of 66 pigs between weaning and market. Antibody concentrations were high (63/65 seropositive) at 4 weeks of age but declined to low levels from 8 to 12 weeks. Mean antibody concentrations rose significantly (p less than 0.001) between 12 and 23 weeks. Between 8 and 23 weeks of age, 33 (51.5%) of 64 surviving pigs seroconverted to A pleuropneumoniae serovar 7. Peak antibody concentrations in the seroconverting pigs usually (28/33) occurred at 23 weeks. Seroconversion to A pleuropneumoniae during the grower/finisher phase was not significantly associated (p greater than 0.05) with passive antibody concentrations at 4 weeks of age, lack of vaccination against Mycoplasma hyopneumoniae, or weaning weight. Pleuropneumonic lesions were evident at slaughter in 4 (6.3%) of 64 pigs. A pleuropneumoniae serovar 7 was isolated from 2 of 4 lungs with pleuropneumonia and from another lung with lesions considered typical of enzootic pneumonia.  相似文献   

17.
A survey for the macroscopic lesions indicative of pneumonic infection in the pig with Haemophilus pleuropneumoniae was made in an abattoir in eastern England. A total of 78 herds located in 11 counties of eastern or central England were seen between December 1982 and August 1983. Lesions were noted in the batches submitted by 44 (56 per cent) of the 78 herds. A further 16 herds (21 per cent) submitted batches containing pigs affected by pleurisy principally of the caudal lobes but without the pneumonic lesions. Lesions suggestive of enzootic pneumonia were also seen in 61 herds (78 per cent). Circumstances restricted corroborative bacteriological examinations to 53 and serological examinations to 33 herds. Strains of H pleuropneumoniae (predominantly serotype 3 but also serotype 2) were isolated from 26 herds. These comprised 22 out of 42 (51 per cent) of those where typically affected plucks, or plucks with caudal lobe pleurisy, were encountered, and four out of 11 (36 per cent) in which there was either no observable thoracic disease or enzootic pneumonia only. Complement fixing antibodies to serotype 3 or 2 antigens occurred in 26 out of 33 herds (79 per cent). These comprised 25 (83 per cent) of 30 herds with batches exhibiting either typical pulmonary lesions and, or, caudal lobe pleurisy and one of three herds without such lesions. Collectively these data indicate that herds containing pigs with pleuropneumonia are common at least in the more easterly parts of England and that H pleuropneumoniae, usually but not always associated with disease, is also widespread.  相似文献   

18.
This investigation addressed the hypothesis that, as a marker of adipocyte differentiation, stearoyl-coenzyme A desaturase (SCD) gene expression would be greater during growth in obese pigs than in crossbred, contemporary pigs. Suckled pigs from a single litter were removed from the sow for sampling at 0, 3, 10, and 17 d. The number of litters at 0, 3, 10, and 17 d of age was zero, two, three, and three (obese sows) and four, two, three, and three (crossbred sows), respectively. Postweaning pigs were removed from the sow at 14 d of age. One set of postweaning pigs was fed a high-fat, milk-based diet from d 28 to 49; pigs were killed on d 28 and 49 for sampling. The grain-fed pigs were switched to a pelleted, grain-based grower diet at d 28, and samples were obtained at 31, 35, or 49 d of age. Adipose tissue from all pigs in a litter for preweaning and postweaning pigs was pooled for the measurement of cellularity and SCD mRNA. There were significant genetic and age effects for adipocyte diameter and volume; overall, adipocytes from obese pigs were larger than those from crossbred pigs. Stearoyl-coenzyme A desaturase mRNA was barely detectable at 0 d of age and increased (P < .01) by 20-fold by 49 d of age. There was a significant genetic x age interaction (P = .026); there was more SCD mRNA in adipose tissue from obese pigs than in that from crossbred pigs during the suckling period, whereas crossbred pigs exhibited greater SCD gene expression than obese pigs during the postweaning period. The lesser SCD gene expression in postweaning obese pigs was caused by a strong depression in SCD gene expression in the grain-fed obese pigs. The data indicate that SCD gene expression provides a marker for terminal differentiation, especially in preweaning pigs. Furthermore, these results provide additional evidence that SCD gene expression is up-regulated by diets high in saturated fatty acids.  相似文献   

19.
断奶应激对仔猪肠黏膜形态的影响   总被引:3,自引:0,他引:3  
在仔猪断奶过渡期,胃肠结构受损是很普遍的,断奶后一段时间内,胃肠结构受损程度不同,本文研究了断奶后7d内(断奶后0-6d),仔猪小肠黏膜形态的变化,试验仔猪28日龄断奶。试验分7组,每组6头仔猪。从断奶当天开始,每1d定时定点剖杀取小肠前段,小肠中部,小肠后段作组织切片,观察其绒毛高度,隐窝深度。结果表明,断奶后前4d,绒毛高度缩短,隐窝加深,断奶后第4d绒毛高度最短,断奶后第5d开始恢复。  相似文献   

20.
In this study, the rate of S. scabiei var. suis transmission among finishing pigs was quantified in a contact transmission experiment. Forty piglets originating from a mange free farrow-to-finish herd were randomly allocated to three groups and one S. scabiei var. suis infested finishing pig was subsequently added to each of these groups. After 35 days, the three seeder pigs were removed from the groups and the remaining 40 pigs were re-allocated to five pens. Ear scrapings, to be examined for mites, were collected from each pig on days 1, 14, 28, 42, 56, and 84 of the experiment. Blood samples, to be tested for antibodies against S. scabiei, were collected from each pig on days 0, 14, 28, 42, 56, 70, 84 and 112 after the introduction of the seeder pigs.From the results of the ear scrapings and the blood samples the number of susceptible (not infested) and infested pigs was derived at the time of each sample collection and the number of new infestations in the intervals between the sample collections. From these data the infestation rate parameter beta (average number of new infestations per infested pig per day) was estimated by use of a Generalised Linear Model (GLM) and accordingly, beta was estimated at 0.056 (95% CI: 0.037-0.085) infestations per infested pig per day.Next, by use of beta, the transmission of S. scabiei was simulated in a population of 100 finishing pigs for 100 days after the introduction of a single infested pig. For this purpose, 500 simulations were done. The 90% confidence interval of the number of infested pigs at day 100 ranged from 12 to 88 (median: 63). It was concluded that transmission of S. scabiei among finishing pigs is slow. Due to the presumed lower contact rate between sows as compared to finishing pigs, it is anticipated that transmission of S. scabiei among sows will even be slower than among finishers These findings are of particular interest for the development of surveillance programmes for S. scabiei free herds.  相似文献   

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