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1.
B. R. JONES A. WALLACE† W. HANCOCK‡ D. R. K. HARDING† A. C. JOHNSTONE‡ 《The Journal of small animal practice》1985,26(1):33-41
A 1,1/2 year-old neutered male cat was presented with a non pruritic skin disease. Pale plaque-like lesions were present on the face, head, axillae and ventral abdomen. Hypercholesterolaemia, hypertriglyceridaemia, hyperglycaemia and glycosuria were all present and histopathological examination confirmed that the skin lesions were xanthomata. A lipoprotein profile revealed an increase in chylomicrons, very low density lipoproteins and low density lipoproteins, and low post heparin lipoprotein lipase activity was present. A diagnosis of diabetes mellitus was made and following treatment with insulin and a change to a low fat, low carbohydrate diet the cat had normal values for blood lipids and glucose and the skin lesions had resolved within a month. 相似文献
2.
性成熟前小鼠生精细胞的发育过程 总被引：1，自引：0，他引：1
用光镜、电镜观察了生后 1～ 1 8d昆明白小鼠的生精上皮。结果显示 ,生后 1～ 3 d,曲细精管内只有生殖母细胞和支持细胞 2类形态结构截然不同的细胞 ,前者位于管中部 ;生后 4～ 5d,少数生殖母细胞已附着在基膜上 ;生后 6～ 7d,原始 A型精原细胞大量出现并附着在基膜上 ;生后 8d,A型精原干细胞大量出现 ,B型精原细胞开始出现 ;生后 1 0 d,B型精原细胞大量出现 ;生后 1 2～ 1 3 d,前初级精母细胞出现 ,少数曲细精管的管腔开始出现 ;生后 1 4～ 1 5d,多数曲细精管管腔基本形成 ,前初级精母细胞大量出现。本试验的结果表明 ,7～ 8d小鼠的睾丸最适于分离精原干细胞 相似文献
3.
Purified FMD virus was heat treated and then examined by electron microscopy with the negative contrast technique. Fibrils of varying length and thickness were present; they were not present after ribonuclease treatment. They were similar to the fibrils described for other picornaviruses. Viral RNA was the essential component of these artificially arranged fibrils, which were composed of threads about 10 A wide, separated from one another by a gap of about 10 A. 相似文献
4.
An IgG-binding protein A homolog in Staphylococcus hyicus 总被引：1，自引：0，他引：1
Shotgun phage display was used to identify a homolog of the IgG-binding protein staphylococcal protein A in Staphylococcus hyicus type strain CCUG 15602/ATCC 11249. This bacterium is the causative agent of exudative epidermitis in pigs and can also cause mastitis in cattle. A protein with similar features as the originally identified protein A in Staphylococcus aureus was described; an YSIRK-type signal peptide, four IgG-binding domains, a putative peptidoglycan-binding domain, and a cell wall anchoring motif (LPXTG) was present. The highest degree of similarity was to a protein A homolog in Staphylococcus pseudintermedius. However, typical Xr polypeptide repeats present in the protein A of S. aureus and S. pseudintermedius could not be identified in the protein A of S. hyicus. The presence of the spa gene in ten porcine and eight bovine clinical isolates of S. hyicus was investigated by PCR. In all isolates, the spa gene could be detected but the amplicons were of two sizes. Sequence analysis of four selected PCR amplicons showed that only three IgG-binding domains were present in the protein A of clinical isolates generating a smaller spa fragment. The finding of spa in S. hyicus contributes to an increased understanding of potential virulence factors in this species. 相似文献
5.
Bagley RS Silver GM Gavin PR 《Journal of the American Animal Hospital Association》2000,36(5):413-415
A 21-kg, seven-year-old, male, mixed-breed Labrador retriever was admitted for incoordination and a head tilt of approximately three months' duration. Ataxia was noted of the trunk and limbs, and there was a head tilt to the right side. Conscious proprioceptive deficits were present in the left thoracic and pelvic limbs (i.e., hemiparesis). These abnormalities were consistent with paradoxical vestibular syndrome and a lesion involving the caudal cerebellar peduncle. A mass lesion consisting primarily of fluid was present on magnetic resonance imaging and at craniectomy. Histopathological diagnosis was a cystic meningioma. Based upon previous reports and experience, the location of this tumor was unusual. 相似文献
6.
A diagnosis of fibrocartilaginous embolism was made in a mature mixed-breed sow with a history of an acute onset of pelvic limb paralysis. Within a single section of lumbar spinal cord, there was severe focally-extensive infarction of the right ventral gray horn. Within affected white matter, there was dilatation of multiple myelin sheaths with concurrent axonal swelling. A smaller focus of infarction was present on the contralateral side. Arteries at the periphery of both lesions contained a blue-gray material with staining characteristics similar to that evidenced by the nucleus pulposus present within intervertebral discs. Grossly, no abnormalities were present within the vertebral column. 相似文献
7.
Four of six cockatiels died within a week after being purchased from a commercial breeder. A fifth bird was euthanatized and necropsied during this time, and tissues were collected for microscopic examination. The small intestine had moderate numbers of Cryptosporidium sp. parasites present. A few large, basophilic intranuclear inclusions were present in renal ductular epithelium. Cryptosporidium sp. oocysts were found in the feces of the surviving bird. Thirty oocysts were 7.2 by 5.5 microns. The shape index was 1.31. Morphological examinations of the fecal oocysts indicated that the Cryptosporidium species infecting the cockatiels was similar to C. baileyi, a parasite that is not usually associated with small-intestinal infections. 相似文献
8.
A case of primary parotid salivary gland adenocarcinoma is described in a three-year-old entire female great dane. The presenting complaint was sudden onset blindness concomitant with the development of bilateral hyphaema and anterior uveitis. A soft-tissue swelling of the left subaural region and right forelimb lameness were also present. A definitive diagnosis of primary parotid salivary gland adenocarcinoma with bilateral ocular metastases was made on post mortem examination. Metastases were also present in the right proximal humerus, left and right prescapular lymph nodes, left axillary lymph node, left retropharyngeal lymph node, bronchial lymph nodes and all lung lobes. 相似文献
9.
Emphysematous cholecystitis not associated with diabetes mellitus was diagnosed in three dogs. All three dogs were examined because of vomiting. Neutrophilia, elevated serum alkaline phosphatase, and normal serum glucose were present in each animal. A gas-filled gallbladder and pericholecystic gas were seen radiographically in all three dogs; a cholecystolith was present in one dog. A cholecystectomy was performed on two dogs. Cultures of bacteria from these two bladders revealed Clostridium sp. One of these dogs was euthanized because of acute renal tubular necrosis that was diagnosed after ten days of treatment with gentamicin. The second dog recovered without incident. The third dog was treated successfully with antibiotics. 相似文献
10.
Harvey JW Kociba GJ Peteya DJ 《Veterinary clinical pathology / American Society for Veterinary Clinical Pathology》1990,19(2):55-58
A macrocytic hypochromic anemia, with marked reliculocytosis and large numbers of circulating nucleated erythrocytes, was recognized in a 3 1/2-year-old male Beagle-cross dog. A presumptive diagnosis of erythrocyte pyruvate kinase (PK) deficiency was made, even though PK activity from the patient was within the range of activities measured for normal dogs, because the PK activity should have been several times normal in light of the large number of reticulocytes present. The PK activity in a hemolysate from the patient was heat-labile compared to activities in hemolysates from normal dogs, a finding consistent with results from a previous study of PK-deficient Basenji dogs. Seven phosphorylated glycolytic intermediates and 2,3-diphosphoglycerate were measured in protein-free extracts of erythrocytes from the patient. All were present in concentrations above that present in normal canine erythrocytes, further supporting the diagnosis of PK deficiency. 相似文献
11.
Jorgen S Agerholm Christian Bendixen Jens Arnbjerg Ole Andersen 《Journal of veterinary diagnostic investigation》2004,16(6):548-553
A study was performed to investigate the morphological expression of the inherited syndrome "complex vertebral malformation" (CVM) in Holstein calves. A total of 107 late-term aborted, premature, or neonatal calves suspected of having CVM were necropsied and retrospectively analyzed for the causal mutation in the gene SLC35A3. Sixty-two calves were homozygous affected, 16 were heterozygous, and 29 were homozygous normal. Calves affected by CVM were growth retarded. Vertebral lesions identified by radiography were present in 61 cases, of which 58 also had costal malformation. Malformation of the head, primarily in the form of dysplasia or palatoschisis, was present in 15 cases. Bilateral symmetric flexion of the carpal and metacarpophalangeal joints was present in all cases, whereas posterior arthrogryposis was found in 54 cases. Interventricular septal defects occurred in 33 calves, often in combination with other cardiac malformations. A wide spectrum of additional malformations was found. Other congenital syndromes were in most cases distinguishable from CVM on a morphological basis. However, a calf with a prenatal infection with bovine virus diarrhea virus constituted a phenocopy. The study demonstrated that the morphological expression of CVM is wide, but certain aspects, i.e., growth retardation, vertebral malformation, and symmetric arthrogryposis, are almost constant findings. However, cases without vertebral defects and phenocopies constitute a diagnostic problem. A presumptive diagnosis of CVM can in most cases be based on necropsy findings combined with information on descent and paternal CVM genotype, whereas a definitive diagnosis requires genotyping. 相似文献
12.
Marcy J. Souza Nancy S. Johnstone-McLean Daniel Ward Kimberly Newkirk† 《Veterinary ophthalmology》2009,12(1):53-55
A 17-year-old female blue and gold macaw ( Ara ararauna ) presented for evaluation of a discreet, conjunctival mass of the OD. No other abnormalities were found on ophthalmic or physical examination. A heterophilic leukocytosis was present on the complete blood count, and elevated aspartate aminotransferase activity, creatinine kinase activity and cholesterol were present on the plasma biochemistry panel. Surgical removal of the mass was complete and no recurrence has occurred by six months after excision. Reduction of dietary fats was recommended to reduce serum cholesterol levels and reduce the likelihood of future occurrence of xanthomas in this bird. 相似文献
13.
J. P. Henderson G. R. Pearson T. N. Smerdon† 《The Journal of small animal practice》1993,34(8):402-404
A young adult Balinese cat developed complete hindlimb paralysis which persisted for six weeks. Clinical findings suggested a lesion compressing the spinal cord and this was confirmed at necropsy. A dermoid cyst was present at the level of the third thoracic vertebra. The cyst was lined by stratified squamous epithelium and contained desquamated keratinised material and hair fragments. Sebaceous glands and hair follicles were present in the connective tissue wall. This is the first report of a dermoid cyst in the spinal cord of a cat. The lesion is considered to be a congenital anomaly. 相似文献
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15.
A 2-year-old, male Weimaraner presented with acute-onset nonaxial exophthalmos with dorsal deviation of the left globe. Periorbital swelling, pain and a profuse purulent ocular discharge were present on the left side. A draining sinus tract was present in the left ventral conjunctival fornix and another in the left pterygopalatine fossa. The right eye was normal on complete ophthalmic examination. Orbital ultrasonography revealed large, double, linear, parallel echogenic bands with shadowing present in the ventrolateral aspect of the left orbit suggestive of a foreign body. Deformation of the posterior segment was also present. Removal of the orbital foreign body was attempted under ultrasound guidance via the discharging sinuses in the ventral conjunctival fornix and the pterygopalatine fossa. Neither approach was successful; however, a small amount of organic material was retrieved confirming the diagnosis of orbital foreign body. Magnetic resonance imaging (MRI) revealed a linear foreign body of 8 x 1.5 x 0.8 cm extending from the orbit to the level of the oropharynx. A modified lateral orbitotomy with zygomatic arch resection on the left side allowed removal of the wooden foreign body. 相似文献
16.
A discrete circumscribed red nodule present on the surface of the proventriculus of a 7-week-old broiler was diagnosed as a hemangiosarcoma. Histologically, discrete islands and dense sheets of anaplastic ovoid to spindle-shaped basophilic cells surrounded irregular vascular clefts and spaces. Mitotic figures were focally numerous, and extension into the tunica muscularis of the proventriculus was seen. Neoplastic islands were also present in the tunica mucosa and the adjacent mesentery. 相似文献
17.
Settled dust samples were collected on a commercial dairy farm in the Netherlands with a high prevalence of Mycobacterium avium subspecies paratuberculosis (MAP) (barn A) and on a Dutch experimental cattle farm (barn B) stocked with cattle confirmed to be MAP shedders. Barns were sampled while animals were present, after both barns were destocked and cleaned by cold high-pressure cleaning, and after being kept empty for two weeks (barn A) or after additional disinfection (barn B). MAP DNA was detected by IS900 real-time PCR and viable MAP were detected by liquid culture. MAP DNA was detected in 78 per cent of samples from barn A and 86 per cent of samples from barn B collected while animals were still present. Viable MAP was detected in six of nine samples from barn A and in three of seven samples from barn B. After cold high-pressure cleaning, viable MAP could be detected in only two samples from each barn. After leaving barn A empty for two weeks, and following additional disinfection of barn B, no viable MAP could be detected in any settled dust sample. 相似文献
18.
A case of corneal sequestrum in a 9-year-old Shih Tzu is reported. On the ophthalmic examination a brown-pigmented ulcer with mild edema and corneal vascularization was present. The brownish plaque was facing an inferior palpebral tumor. A superficial keratectomy followed by a grid keratotomy and removal of the palpebral mass were performed. Histological findings revealed an inflammatory cell infiltration underneath the acellular stromal layers. No melanin granules were observed. No vascular infiltration was present within the necrotic stroma. The surgical area healed and no recurrence has been reported by the owners at the time of writing. To the authors' knowledge, this is the first report of a corneal sequestrum in a dog. 相似文献
19.
Tsegaye Habtemariam Richard E. Howitt Roger Ruppanner Hans P. Riemann 《Preventive veterinary medicine》1983,1(2):157-168
A benefit—cost analysis of trypanosomiasis control programs for an area of 1500 km2 in southwest Ethiopia, for a project span of 15 years at a discount rate of 10%, was conducted to determine cost effective and benefit maximizing alternatives. The trypanosomiasis control scenarios considered were: (a) reduction of tsetse flies by use of insecticides sprayed from knapsacks, (b) game reduction, (c) no control program. Information on costs was obtained from existing data. A Leslie type model was utilized to simulate the cattle population dynamics in southwest Ethiopia for trypanosomiasis controlled versus uncontrolled situations. From these results costs and benefits of control were quantified. The benefit—cost analysis using net present values (NPV) and benefit/cost (B/C) ratio as decision criteria of project feasibility and efficiency, indicated that insecticide application was preferable to game reduction. Estimates of present value costs were E$ 630.17 per km2 per year while the present value benefits were E$ 720.24 per km2 per year. The B/C ratio was 1.14 and net present value of the project was E$ 2.03 million. Sensitivity analysis and implications of the results are discussed. 相似文献
20.
A diagnosis of renal dysplasia was made in a six-month-old, male, mixed-breed pig. Both kidneys were small, firm, slightly pitted, and contained an indistinct corticomedullary junction. Histologically, primitive tubules were present surrounded by an abundant loose, mesenchymatous stroma. Occasionally, tubules were markedly dilated and lined by a pseudostratified columnar epithelium forming epithelial mats that obscured the lumina. Immature glomeruli were present. Multifocal glomerular sclerosis was evident. Other mature glomeruli were enlarged and characterized by mesangial cell hyperplasia forming an arborizing pattern. 相似文献