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1.
Benign prostatic hyperplasia was diagnosed in an American Staffordshire Terrier of high breeding value presenting concurrent haematuria. Castration as a treatment was synchronized with the oestrus cycle of a bitch selected for insemination. After castration the cauda epididymis was flushed with Gent semen extender and collected spermatozoa were filtered and analysed by Hamilton Thorn computer assisted sperm analysis. A total of 7 ml semen containing 742 x 10(6) spermatozoa with 76.5% mean motility was used for insemination. Intravaginal insemination of the bitch was performed with an insemination catheter for dogs (Kruuse, Marslev, Denmark) on the day when plasma progesterone levels reached 9.9 ng/ml. Normal pregnancy without complications resulted in eight live-born puppies 63 days after insemination. This is the first report of a normal pregnancy and birth of puppies from a bitch inseminated with epididymal semen obtained from a dog affected by benign prostate hyperplasia.  相似文献   

2.
A 7-month old Boxer bitch with lethargy and inappetence of several days' duration was found to have pancytopenia. A bone marrow aspirate contained many lymphocytes and immature myeloid cells but few erythrocyte precursors; marrow phagocytes appeared active and megakaryocytes were immature. Circumstantial evidence suggested that the cause of marrow failure was prior administration of thiacetarsamide, an organic arsenical. Recovery was spontaneous and within four weeks the haemo-gram was normal, except that platelet numbers were not fully restored.
The bitch was examined 6 months later because of a recurrence of signs, with several syncopic episodes during the preceding week. A severe non-regenerative anaemia was present, with absence of erythroid precursors from bone marrow. Neutrophil and platelet counts were normal. The cause of the erythrocyte aplasia was not determined. The dog was given blood transfusions, oxymetholone and prednisolone but died after one month. A post-mortem marrow sample contained many erythroid cells, some with morphological abnormalities suggesting dyserythropoiesis.  相似文献   

3.
Leeches are bloodsucking hermaphroditic parasites that attach to tissues using two muscular suckers, ingest large amounts of blood and may cause severe anaemia in the host. Two four‐month‐old mixed‐breed dogs (one bitch and one male) were referred with anorexia, retching, hypersalivation and bleeding from the oral cavity. On physical examination, two live leeches were detected on the ventral aspect of the tongue of the bitch and one in a similar position in the male. The leeches were gently detached and removed using Adson tissue forceps after applying vinegar over the area. Microcytic hypochromic anaemia was detected in the bitch and mild leukocytosis in the dog. One month after treatment both animals were re‐examined and a complete blood count was normal. Given that infestation with leeches as described here is associated with contaminated water, the use of clean and safe drinking water is recommended to avoid such diseases.  相似文献   

4.
A limited number of studies have been published concerning intrauterine infusions in the bitch, presumably because it is difficult to pass a catheter into the canine cervix. Cobb (1959) designed an apparatus for hysterosalpingography with which he reported fairly easy catheterization of the cervical canal in the anaesthetized bitch. Recent advances made in the field of deepfreezing of dog semen have emphasized the need for a simple method for intrauterine infusion in the unanaesthetized bitch. The first successful insemination with frozen dog semen was reported in 1969 by Seager. The semen was frozen in pellets and deposited vaginally. Over a six-year period 61 (39.1 %) out of 156 bitches inseminated with this method became pregnant (Seager et al. 1975). Andersen (1972), however, when inseminating dog semen frozen in French straws, reported no success after vaginal deposition of the thawed semen. Based on experience with insemination in Blue foxes Andersen (1975) developed a special catheter which he could introduce through the cervix to deposit the semen into the corpus uteri without anaesthetizing the bitches. With this method 19 (73.1 %) out of 26 bitches became pregnant (Andersen 1977, personal communication). This method of passing the catheter through the cervix requires training and the method is impractical in nervous or obese bitches in which palpation of the abdomen is difficult or impossible. In order to fully use the advantages offered to the dog breeders by deep-freezing of dog semen, it is necessary to develop a simple method of inseminating the bitch that can be employed by practising veterinarians without previous special training. The present investigation was undertaken as an introduction to further studies of the problems related to the use of frozen dog semen.  相似文献   

5.
Canine leishmaniasis during pregnancy is rarely reported, even in countries where the infection in dogs is endemic. The authors report a case of a 4 yr old bitch with leishmaniasis treated with meglumine antimoniate during pregnancy. The pregnancy and delivery were normal and the bitch presented improvement of the infection during treatment. Three puppies died within 2 days of birth and tested negative via real-time PCR for L. infantum. The two surviving puppies were followed clinically, serologically, and by real-time PCR until 1 yr of age with no evidence of congenital leishmaniasis. L. infantum DNA was detected with real-time PCR analysis of uterine tissue from the bitch at the time of ovariohysterectomy. PCR analysis was performed after an ovariohysterectomy of the bitch that was performed two months after parturition. Meglumine antimoniate use in the pregnant bitch may have prevented vertical transmission of leishmaniasis.  相似文献   

6.
Acute renal failure was diagnosed in a German Short Haired Pointer bitch and a Kelpie cross-bred dog following envenomation by Bull ants. Both dogs had been tethered over a Bull ant nest and had experienced mass envenomation. There was local reaction at the envenomation sites and each dog had experienced vomiting that was poorly controlled by symptomatic therapy. Intensive treatment of renal failure was successful in the German Short Haired Pointer and the bitch remains well 19 months after envenomation. The Kelpie cross-bred deteriorated despite intensive treatment and was euthanased 36 hours after presentation. Necropsy examination revealed haemorrhage and necrosis of the small intestine and myocardium, bilateral nephrosis with tubular necrosis, and patchy haemorrhage of the lung alveoli, pancreas and adrenal cortices. Electron microscopy revealed necrosis of the small intestine and hydropic swelling of proximal renal tubules with necrosis of medullary tubules.  相似文献   

7.
An 11-year-old female German Shepherd dog was presented for investigation of progressive enlargement of the abdomen, periodic bloody discharge from the vulva and rapid exhaustion. Transabdominal ultrasonography and lateral abdominal radiography demonstrated an echogenic formation with anechogenic cavities located cranial to the urinary bladder and a homogeneous shadow with an elliptical shape was located caudal to the rib arc. Both showed indistinct borders. Exploratory laparotomy identified bilateral ovarian masses and ovariohysterectomy was performed. Histopathology confirmed ovarian cystadenocarcinoma. The dog remained clinically normal without evidence of metastatic disease 4 months after surgery. Papillary cystadenocarcinoma in the bitch could affect both ovaries and manifests with a rapid growth rate and clinical signs such as rapid exhaustion, abdominal enlargement and vulval discharge. Ovariohysterectomy is the treatment option.  相似文献   

8.
Hypertestosteronemia was diagnosed in a spayed bitch with pituitary-dependent hyperadrenocorticism and perianal adenomas. Serum concentrations of cortisol and testosterone decreased after treatment with mitotane was instituted. Excessive testosterone in this dog was thought to have been produced by the adrenal cortex, possibly in response to excessive ACTH concentrations. Development of androgen- or estrogen-responsive tumors in castrated dogs may be an early indication of adrenocortical hyperfunction.  相似文献   

9.
A Beagle dog (3 years old) that ejaculated high percentages (mean ± SE: 29.1 ± 1.2%) of sperm with a knobbed acrosome abnormality and a low number of sperm and that also had a low plasma testosterone (T) level was given 10 subcutaneous injections of 1 μg of gonadotropin-releasing hormone analogue (GnRH-A) at 3-day intervals. The plasma T level and number of sperm increased 12-14 weeks after the first injection. Although the percentages of sperm with knobbed acrosome abnormality did not change after the GnRH-A therapy, the number of sperm and percentage of actively motile sperm increased after the therapy, and a bitch gave birth to 5 healthy puppies after intravaginal artificial insemination with fresh semen collected 14 weeks after the first injection.  相似文献   

10.
An ovarian teratoma in a 5-year-old bitch with a history of vaginal discharge was removed successfully by ovariohysterectomy. The mass was discovered on abdominal palpation and contained multiple mineralized densities that were visualized radiographically. Histologic examination of the mass confirmed the presence of tissues originating from multiple germ-cell layers, characteristic of a teratoma. Clinical findings in dogs with teratomas include abdominal distention, a palpable abdominal mass, and rarely, evidence of reproductive hormonal activity. These neoplasms are uncommon in the dog, and they may exhibit malignant tendencies, with metastasis developing in approximately 33% of the reported cases. Ovariohysterectomy is the preferred treatment for ovarian teratomas, and this procedure was curative in the dog of this report.  相似文献   

11.
Two female (12 and 14 years old) and one male dog (10 years old) developed haemangiopericytomas. Three copies of chromosome 2 were present in the tumours of all three dogs. Additional alterations were an interstitially deleted chromosome 1, centric fusions 3/34 and 8/15, isochromosome 32 and two unidentified marker chromosomes (M1, M2) in one bitch. In the other bitch, the additional alterations were trisomy 37, centric fusions 8/38 and 30/31, and a derivative chromosome 13 (der13). In the male dog, tandem fusion 2/19 was present in addition to two structurally normal chromosomes 2.  相似文献   

12.
A three-year-old, sexually intact, female American Staffordshire terrier was presented with chronic postpartum vulvar haemorrhage. Sixty-one days before presentation, the bitch had whelped 10 puppies. A tentative diagnosis of subinvolution of placental sites was made when syncythial trophoblast-like cells were identified in the specimen collected through the opening of the cervix by endoscopy. Five weeks after the diagnosis, the bitch was clinically healthy with no vaginal bleeding and spontaneous recovery occurred without surgical treatment.  相似文献   

13.
A bitch was inoculated subcutaneously and intramuscularly with Neospora caninum tachyzoites on Day 35 of pregnancy. Eight pups were born 28 days later. Five pups became ill and necropsies were performed before 20 days of age. Three pups and the bitch remained clinically normal for 7 weeks after parturition when they were intramuscularly injected with 40 mg kg-1 methylprednisolone acetate weekly to activate chronic N. caninum infection. Necropsies were performed 48, 17, 18, and 18 days respectively after administration of corticosteroids. Hepatic necrosis, pneumonia, encephalomyelitis, and myonecrosis were the main changes seen in these dogs.  相似文献   

14.
选择 3只年龄为 3岁处于乏情期的苏北红犬和 6只 1～ 2岁未发情的罗威纳犬 ,用溴隐亭处理后有 4只母犬发情 ,1只母犬受孕而后流产。分析犬血清中雌二醇和孕酮水平 ,发情受孕犬雌二醇和孕酮分泌呈现规律性变化趋势 ;发情未受孕犬在雌二醇分泌峰出现后孕酮分泌不稳定 ;而未发情犬雌二醇和孕酮没有变化。结果表明 ,溴隐亭能够有效地缩短母犬的乏情期 ,溴隐亭处理后不同生理状态母犬反应差异较大 ,发过情的母犬作用明显 ,对从未发过情的母犬效果较差  相似文献   

15.
A female, stray crossbreed dog, approximately four years old, was presented for routine spaying during a charity neutering programme in Romania. On clinical examination the bitch was lethargic and pyrexic (40.6 degrees C), but no other signs of illness were detected. Laparotomy revealed an enlarged uterus, severed at the cervix, with no communication to the vagina. Abdominal inspection showed an apparently normal, ligated vaginal stump. An ovariohysterectomy was performed and the dog was treated with a seven-day course of netilmicine. It subsequently made a full recovery.  相似文献   

16.
A 10‐year‐old golden retriever bitch was treated for diarrhea and vomiting that lasted about 1 month without a specific diagnosis until a hepatic biopsy provided a histopathologic diagnosis of lymphoma. The dog was referred to the Swedish University of Agricultural Science and treated with one dose of l ‐asparaginase. The day after chemotherapy, the urine was dark yellow, very turbid, and had large amounts of small amorphous crystals and many casts made of similar appearing material identified by infrared spectroscopy to be 100% uric acid dihydrate. Serum uric acid was elevated at 224 μmol/L (RI 0‐59). The dog's illness became worse after chemotherapy. Lymphoma treatment was not continued, and the dog was euthanized 9 days after the l ‐asparaginase treatment. Among other problems were persistent proteinuria with a urine protein‐to‐creatinine ratio of 2.3 and severe hypoalbuminemia. Serum protein electrophoresis performed 3 weeks prior to chemotherapy indicated hyperproteinemia (total protein 78 g/L) having a biclonal gammopathy with 35 g/L β‐2 globulins and 11 g/L γ globulins. Despite prominent cylinduria and crystalluria, the patient did not develop azotemia or isosthenuria.  相似文献   

17.
A 2-year-old intact miniature pinscher bitch that had been on a bones and raw foods diet since birth showed no signs of estrus despite a 40-day course of cabergoline. Elevated levels of thyroxine were detected in the serum (51 nmol/L) and in the juice of the meat (183 nmol/L) fed to the dog. Change in diet and treatment with oral cabergoline resulted in signs of proestrus in 13 d, pregnancy, and normal birth of 5 puppies.  相似文献   

18.
A young pregnant rottweiler bitch was presented with a large mass of tissue protruding through the vulvar lips. Foetal death was diagnosed on ultrasonography, and ovariohysterectomy was performed, at which time the bladder was observed to be dislocated caudally into the pelvic cavity under the vagina. The bladder was manually repositioned during surgery. One week later, the bitch was healthy with no evidence of dysuria, stranguria or urinary incontinence. Two months later, the owner reported that the bitch was clinically normal with no recurrence of the retroflexion. To the authors' knowledge, this is the first reported case of retroflexion of the urinary bladder during pregnancy.  相似文献   

19.
The surgical treatment of vaginal leiomyoma in a seven year old Blue Heeler bitch is described. A smooth, 12 cm diameter submucosal, intraluminal, firm mass was found on vaginal examination. It appeared to arise from the left ventral vaginal wall, cranial to the clitoris but caudal to the cervix. There was no history of urinary problems and the dog was normal in all other aspects. The treatment was surgical excision of the mass via an episiotomy. Histological examination indicated a leiomyoma. The differential diagnoses, possible etiologies and control or prevention of the condition by ovariohysterectomy are also discussed.  相似文献   

20.
Endogenous progesterone and synthetic progestins may induce hypersecretion of growth hormone (GH) of mammary origin, hyperplastic ductular changes in the mammary gland, and the development of cystic endometrial hyperplasia (CEH) in dogs. It was investigated whether progestin-induced mammary GH plays a role in the pathogenesis of CEH in the bitch. During 1 year, bitches with surgically excised mammary glands and healthy control bitches received medroxyprogesterone acetate (MPA). Before and after MPA treatment, uterine and mammary tissues were collected for histological, immunohistochemical, and RT-PCR examination. After MPA administration, the mammary tissue in the control dogs had differentiated into lobulo-alveolar structures and CEH was present in all uteri of both dog groups. In the MPA-exposed mammary tissue of the control dogs, GH could only be demonstrated immunohistochemically in proliferating epithelium. After treatment with MPA the dogs of both groups had immunohistochemically demonstrable GH in the cytoplasm of hyperplastic glandular uterine epithelial cells. RT-PCR analysis of the mammary gland tissue after MPA administration demonstrated a significant higher GH gene, and lower GHR gene expression than before treatment. In the uterus, the expression of the gene encoding for GH was significantly increased in the mastectomized dogs, whereas in the control dogs the expression of the gene encoding for insulin-like growth factor-I had significantly increased with MPA administration. MPA treatment significantly down regulated PR gene expression in the uterus in both dog groups. These results indicate that progestin-induced GH of mammary origin is not an essential component in the development of CEH in the bitch.  相似文献   

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