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Bartonellosis has been widely studied in human and veterinary medicine over the past two decades. Despite this fact, it remains an enigmatic disease in many ways. The causative bacteria, Bartonella spp, are transmitted to cats by fleas and thus the prevalence in cat populations, particularly in temperate climates, is high. Most cats, whether infected naturally or experimentally, remain asymptomatic. Thus, correlating the presence of the organism to clinical disease, including uveitis, in cats has been difficult. This review summarizes what is known of the transmission and pathogenesis of Bartonella spp in cats, the possible role of the organism in feline ocular disease, as well methods of diagnosis and treatment.  相似文献   

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Extract

A 4-year-old Male Bull Terrier was presented with excessive thirst, inappetance of 2-days duration, and rapid weight-loss.  相似文献   

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The term 'inflammatory airway disease' (IAD) is often used to describe the syndrome of lower airway inflammation that frequently affects young racehorses in training around the world. In practice, this inflammation is generally diagnosed using a combination of endoscopic tracheal examination, including grading of amounts of mucus present and tracheal wash sampling. However, a recent consensus statement from the American College of Veterinary Internal Medicine concluded that bronchoalveolar lavage (BAL) sampling, rather than tracheal wash (TW) sampling, is required for cytological diagnosis of IAD and that tracheal mucus is not an essential criterion. However, as BAL is a relatively invasive procedure that is not commonly used on racing yards, this definition can only be applied routinely to a biased referral population. In contrast, many practitioners continue to diagnose IAD using endoscopic tracheal examination and sampling. We argue that, rather than restricting the use of the term IAD to phenotypes diagnosed by BAL, it is important to distinguish in the literature between airway inflammation diagnosed by BAL and that identified in the field using TW sampling. We suggest the use of the term brIAD for the former and trIAD for the latter. It is essential that we continue to endeavour to improve our understanding of the aetiology, pathogenesis and clinical relevance of airway inflammation identified in racehorses in training using tracheal examination and sampling. Future studies should focus on investigations of the component signs of airway inflammation.  相似文献   

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Bank voles can harbour Puumala virus (PUUV) and vole populations usually peak in years after beech mast. A beech mast occurred in 2014 and a predictive model indicates high vole abundance in 2015. This pattern is similar to the years 2009/2011 when beech mast occurred, bank voles multiplied and human PUUV infections increased a year later. Given similar environmental conditions in 2014/2015, increased risk of human PUUV infections in 2015 is likely. Risk management measures are recommended.  相似文献   

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Abstract: An 11‐year‐old female spayed Whippet dog was referred to the Veterinary Hospital of the National Veterinary School of Lyon with a 3‐month history of chronic bleeding, cutaneous masses suggestive of hematomas, and hemorrhagic diarrhea. Laboratory abnormalities included leukopenia with neutropenia and lymphopenia, rouleaux formation, marked hyperproteinemia with hyperglobulinemia and normoalbuminemia, hypercalcemia, markedly increased serum urea concentration, mildly increased creatinine concentration, and proteinuria. Hemostatic screening tests showed marked prolongation of thrombin time, increased concentrations of fibrin(ogen) degradation products and D‐dimers, and slightly prolonged activated partial thromboplastin time. Serum and urine protein electrophoresis revealed a monoclonal peak identified as IgM by immunoelectrophoresis and an M‐spike, respectively. Cytologic evaluation of bone marrow revealed a hypocellular sample with lymphoplasmacytic cells comprising approximately 50% of all nucleated cells. These findings were consistent with a diagnosis of Waldenström's macroglobulinemia with secondary bleeding diathesis. Treatment with prednisone and chlorambucil was initiated, and the dog had a good response.  相似文献   

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Sézary syndrome is an uncommon leukemic variant of cutaneous lymphoma in cats. This cat had recurrent dermatitis with erythematous, pruritic plaques. Multiple skin imprints and biopsy samples were obtained over a 6-month period, and histopathological findings were consistent initially with eosinophilic miliary dermatitis and later with erythema multiforme. One week before death, Sézary cells were identified in the peripheral blood that expressed cluster of differentiation (CD)3 and CD8 antigens. Massive infiltration of CD3+ lymphocytes was noted in the skin and multiple internal tissues by histopathological examination. This case demonstrates the difficulty in diagnosing cutaneous lymphoma early in the disease course.  相似文献   

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Summary

Zollinger‐Ellison Syndrome in a 12‐year old castrated male European Shorthair cat is described. The clinical symptoms were vomiting, weight loss, listlessness and alternating diarrhoea and obstipation.

An endocrine tumour near the pancreatic duct had metastasised to the liver. Many duodenal ulcers were present. Immunohistochemistry revealed cells positive for gastrin and neuronspecific enolase (NSE) scattered throughout the tumour.  相似文献   

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Concentrations of serum calcium, phosphorus, sodium, chlorine and potassium of growing yak born from a nuclear breeding herd in 1995,1996 and 1997(classified as groups G3, G2 and G1) were determined bimonthly from September 1997 to July 1998. The result showed that the concentrations of serum macro-minerals demonstrated a month/season pattern and both calcium and phosphorus reached the highest in September(11.36mg/dl and 6.82 mg/dl, respectively). The animals in G1 had a very high serum phosphorus concentration due to their young age and incomplete weaning in the early times of sampling. The ratio of calcium to phosphorus was generally higher than that recommended for cattle and demonstrated a great variation in month/season. The results indicated that the deficiencies of phosphorus, sodium and probably calcium were common in the pasture on the Qinghai-Tibetan Plateau.  相似文献   

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Digital venography is a contrast angiography technique used to study digital vascularity. The technique is simple to be carried out and can be performed under field conditions using a standard radiographic unit. The venogram examination is used to complement conventional radiographic examinations in animals affected by foot diseases. Discrepancy in the contrast vascular pattern may be observed before the clinical signs of the foot disease. Digital venography studies in ruminants are in smaller number than those in horses. The herein presented review discusses digital venography techniques used in ruminants as well as the differences and similarities between ruminants (cattle, sheep and goat) and horses.  相似文献   

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Parturient haemoglobinuria is a disease of economic importance in buffalo rearing countries in general and in India, Pakistan and Egypt in particular.This study reviews the information on aetiology, epidemiology, clinical aspects and treatment of parturient haemoglobinuria in buffaloes. The body of literature reviewed suggests that phosphorus deficiency in the diet of affected animals plays a major role in causing this disease, although the precise mechanism involved is complex. The possible factors involved and their interplay, plus the clinical picture of affected animals and the results of different preventive and therapeutic regimes are discussed. The study also identifies areas for further research.  相似文献   

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Signs of progressive central nervous system disease in cattle aged 2 years and older should alert farmers and veterinarians to consider the possibility of bovine spongiform encephalopathy (BSE). Government veterinarians routinely assess all livestock slaughtered in meat plants in New Zealand for signs of any nervous disorder, including abnormalities of behaviour and mental state and abnormalities of posture and gait.  相似文献   

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An 18-day-old heifer was presented with fever, depression, tachycardia, tachypnea, and prolonged bleeding time. Blood tests revealed severe anemia, thrombocytopenia, and leucopenia. The animal was negative by PCR for bovine virus diarrhea virus antigen. The findings supported a diagnosis of bovine neonatal pancytopenia. Treatments included fresh whole blood transfusion and antibiotics. The animal recovered fully.  相似文献   

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Abstract A 1.5‐year‐old male Arabian horse was referred to the Louisiana State University Veterinary Teaching Hospital and Clinic for an open deep laceration involving two thirds of the right trunk. The initial CBC results included an inflammatory leukogram, characterized by a marked degenerative left shift consisting of only immature band neutrophils (7500/μL, reference interval 0–100/μL) with toxic changes and no segmented neutrophils (0/μL, reference interval 2700–6700/μL). On abdominal ultrasonography, free abdominal fluid was found and collected for analysis. Abdominal fluid had a marked increase in total nucleated cells (40,600 cells/μL) consisting of 74% nondegenerate neutrophils that all were hyposegmented, with mature condensed chromatin. Re‐evaluation of neutrophil morphology on the initial blood smear confirmed hyposegmentation and mature condensed chromatin, similar to that observed in cells in the abdominal fluid. A diagnosis of Pelger‐Huët anomaly (PHA) was made in this colt. Congenital PHA was documented on the basis of persistent neutrophil hyposegmentation on serial blood smears, ruling out of acquired causes of PHA, and findings of similar neutrophil hyposegmentation on blood smears from the colt's sire and the sire's siblings. To our knowledge, this is the first reported case of congenital PHA in a horse.  相似文献   

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Behavior problems in horses are often thought to be due to the horse’s bad attitude, which commonly results in them being punished. However, when these cases are carefully worked up, there may be an underlying physical problem, and pain may play an important role. A 5-year-old Dutch Warmblood mare was presented for rearing and flipping over backward. The mare had been repeatedly examined by an equine veterinarian and a nonveterinarian equine dentist who found no abnormalities. Several different bits were tried, and side reins were used to keep her head down. The mare was whipped every time she reared. None of these measures helped. On presentation to our equine teaching hospital, no abnormalities were detected on routine physical examination. The behavior was observed when the mare was lunged; as soon as a small amount of tension was put on the lunge rein, the mare shook her head horizontally for approximately 1-2 seconds, reared, and flipped over onto her back. Neurological examination revealed that the mare was slow to resume a normal stance when her hind legs were placed in an abnormal position. Dental examination and endoscopy of the upper airways proved unremarkable. Radiography of the atlanto-occipital joint area revealed fractures of the first and second cervical vertebrae and fracture fragments, which are both suggestive for the presence of cervical instability and the possible presence of spinal cord compression. These suggestions were further supported by identification of delayed postural reflexes during neurological examination. The mare was deemed unfit for dressage and was successfully kept for breeding. Horses are frequently punished for “bad behavior.” These behaviors are frequently due to underlying physical problems and not a “nasty” horse. This case highlights the importance of careful history taking and a thorough veterinary examination with the use of further diagnostics (if necessary) when dealing with equine behavior problems.  相似文献   

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The effects of mycotoxins are well known since antiquity. Modern trace analysis show the wide prevalence of mycotoxins in the food chain. Aflatoxins (AFB1, AFB2, AFG1, AFG2), trichothecenes (deoxynivalenol, T-2 Toxin, HT-2 Toxin), zearalenone, fumonisins (FB1, FB2) and ochratoxin A are the most important mycotoxins world wide. Foods of plant origin are normally contaminated more frequently and in higher concentrations than food of animal origin. The mean concentrations of mycotoxins analysed in European foods can be assed as low. This may be one reason why acute poisonings are rare incidences and why the limits of the tolerable daily intake (TDI) levels are exceeded only very seldom; however the population group "infant" exceed the preliminary TDI-level for trichothecenes. The consequences of a chronic intake of low amounts of mykotoxins is hardly to assess. A participation of the aflatoxins in the pathogenesis of primary liver cancer is considered as certain. Other coherence between the dietary intake of mycotoxins and specific clinical symptoms of man are not convincingly shown till now.  相似文献   

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