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1.
蜂胶对糖尿病大鼠血糖的影响   总被引:2,自引:0,他引:2  
将复制糖尿病模型的 72只SD大鼠随机分为模型组 ,蜂胶水提液低剂量组、高剂量组 ,蜂胶醇提液低剂量组、高剂量组和阳性对照组 (拜糖苹 ) ,另取 12只为正常组。除正常组和模型组外 ,各组分别给予不同的试验药物。给药过程中 ,每周取血一次 ,测空腹血糖 ,给药 7周后 ,取血测定空腹血糖和果糖胺。试验结果表明 ,蜂胶水提液和醇提液均能控制糖尿病大鼠空腹血糖的升高 ,并且随着时间的延长效果越来越明显。  相似文献   

2.
不同方法提取的蜂胶液调节血脂作用的实验研究   总被引:3,自引:0,他引:3  
测定和比较了蜂胶水提液、蜂胶醇提液对实验性高脂血症IRC小鼠血脂及脂蛋白的影响。结果表明,不同的蜂胶提取液均能有效抑制高脂血症ICR小鼠血清甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白(LDL—C)的升高,蜂胶醇提液能显著提高血清高密度脂蛋白(HDL—C)浓度,表明蜂胶能够改善高脂血症小鼠的脂肪代谢。  相似文献   

3.
蜂胶对糖尿病大鼠蛋白质代谢的影响   总被引:6,自引:0,他引:6  
将复制糖尿病模型的72只SD大鼠随机分为模型组,蜂胶水提取液1(WSP1),蜂胶水提取液2(WSP2)蜂胶醇提取液1(EEP1),蜂胶醇提取液2(EEP2),阳性对照组(拜糖苹),另取12只为正常组。除正常组和模型组外,各组分别给予不同的实验药物,给药7周后,抽血测总蛋白、白蛋白,同时计算球蛋白和白蛋白,球蛋白。结果发现,蜂胶能降低糖尿病大鼠体内蛋白质的消耗,升高糖尿病大鼠体内总蛋白、白蛋白水平,同时升高白蛋白,球蛋白的比值。表明蜂胶可以调节糖尿病大鼠体内蛋白质的代谢。  相似文献   

4.
蜂胶对糖尿病大鼠肾脏的影响   总被引:3,自引:0,他引:3  
将复制糖尿病模型的72只SD大鼠随机分为模型组、蜂胶水提液低剂量组(WSP1),蜂胶水提液高剂量组(WSP2)、蜂胶醇提液低剂量组(EEP1)、蜂胶醇提液高剂量组(EEP2)和阳性对照组,另取12只为正常组.除正常组和模型组外,各组分别给予不同的试验药物.给药7周后,抽血测生化指标,同时取肾脏,计算肾脏/体重.结果发现蜂胶能降低糖尿病大鼠的尿酸、尿素、肌酐水平,并且蜂胶给药组大鼠的肾重/体重均比模型组低,表明蜂胶对糖尿病机体内的肾脏组织具有保护作用.  相似文献   

5.
目的:研究蜂胶乙醇提取物在用四氧嘧啶制造糖尿病大鼠模型过程中的保护作用。方法:对大鼠进行分组。用蜂胶对大鼠进行连续灌胃,30天后,对大鼠注射四氧嘧啶,观察各组大鼠的状态及血糖变化;观察蜂胶对糖尿病大鼠模型的影响。结果:实验前后分别测定各组大鼠的空腹血糖,蜂胶灌胃组跟对照组相比较,蜂胶灌胃组能明显降低大鼠的血糖,蜂胶灌胃组大鼠跟模型组大鼠相比较P<0.01,大鼠状态明显较好;蜂胶能明显降低糖尿病大鼠的血糖。结论:蜂胶能调节血糖,预防和治疗糖尿病。  相似文献   

6.
90只SPF级SD系大鼠随机分为空白对照组、免疫抑制对照组、免疫抑制微小隐孢子虫感染组(n=30)。免疫抑制感染组大鼠一次性接种1×106/L微小隐孢子虫卵囊液1mL,对照组接种1mL的生理盐水。于0,2,7,13,19d采集血样,检测大鼠血液红细胞、白细胞、血红蛋白含量及大鼠血清总蛋白、尿素氮、肌酐、甘油三酯、尿酸、总胆固醇、血糖含量变化,以研究微小隐孢子虫感染对大鼠血液部分生理生化指标的影响。结果表明:大鼠感染微小隐孢子虫后,对大鼠血液生理指标有一定的影响,但对生化指标没有明显的影响。  相似文献   

7.
将90只ICR小鼠随机分为模型组、蜂胶水提液低剂量组(WSPI)、蜂胶水提液高剂量组(WSP2)、蜂胶醇提液低剂量组(EEP1)、蜂胶醇提液高剂量组(EEP2)和阳性对照组(拜糖苹),首先测空腹血糖,然后给予不同的受试药物,1周后,所有小鼠禁食测空腹血糖,然后给予饲料,2h后测餐后血糖。结果发现,蜂胶对正常小鼠的空腹血糖和餐后血糖影响不显著,表明蜂胶对正常小鼠的血糖没有影响。  相似文献   

8.
蜂胶复合软胶囊对实验大鼠血脂的调节作用   总被引:3,自引:0,他引:3  
研究蜂胶复合软胶囊对大鼠血脂代谢的影响 ,并探讨其作用机理。方法 :通过动物实验 ,观察蜂胶复合软胶囊对大鼠血清三酰甘油 (TG)、血清总胆固醇 (TC)、高密度脂蛋白胆固醇 (HDL -C)的影响。结果表明 :蜂胶复合软胶囊灌胃的大鼠 ,其血清总TG ,TC含量明显降低 ,表现出良好的防治高血脂症的作用。在降低血清脂质含量的同时 ,明显增高了HDL -C的含量。由于蜂胶复合软胶囊是以蜂胶为主的纯天然复合制剂 ,并且同时具有调节血糖的作用 ,因此对防治高血脂症及诸如糖尿病一类的代谢性疾病有着积极意义。  相似文献   

9.
蜂胶复合软胶囊降糖作用的实验研究   总被引:5,自引:0,他引:5  
用蜂胶复合软胶囊内容物分别给糖尿病大鼠及正常大鼠灌胃,结果表明,蜂胶复合软胶囊可显著降低四氧嘧啶所致糖尿病大鼠的血糖值,对正常大鼠的血糖也有一定的降低作用,可调节糖尿病大鼠和正常大鼠的血糖水平。  相似文献   

10.
目的探讨从大鼠腹主动脉和后腔静脉采血对其血液生化值的影响。方法采用全自动生化仪对不同部位采集的动物血液中天冬氨酸转氨酶(AST)、丙氨酸转氨酶(ALT)、碱性磷酸酶(ALP)、肌酸激酶(CK)、总蛋白(TP)、白蛋白(ALB)血糖(GLU)、总胆红素(T—BIL)、总胆固醇(CHO)、甘油三酯(TG)、尿素氮(BUN)、肌酐(Crea)、钾(K)、钠(Na)、氯(Cl)等生化指标进行测定。结果大鼠腹主动脉与后腔静脉采集血液生化值比较,在总蛋白上存在显著性差异,表现为前者血清中总蛋白含量明显高于后者。结论建议在长毒试验动物血液生化测定中,采血部位应进行规范与统一。  相似文献   

11.
蜂胶、蜂花粉、蜂王浆抗肿瘤效果的比较研究   总被引:3,自引:0,他引:3  
用蜂胶、蜂花粉水提液和蜂王浆稀释液分别灌胃S180 实体型小鼠 ,15d后解剖称取瘤重 ,计算抑瘤率。结果发现 ,蜂胶、蜂花粉水提液和蜂王浆稀释液的抑瘤率分别达 79 92 %,6 9 0 6 %和 75 83%。  相似文献   

12.
测定了不同方法提取的蜂胶液中黄酮类化合物的含量,并观察了黄酮类化合物含量较高的蜂胶醇提液和水提液对小鼠S180实体瘤模型、小鼠肉芽肿模型、大鼠急性关节炎模型和大鼠急性胸膜炎模型的影响.结果发现,在乙醇提取中,80%的乙醇提取液中的黄酮类化合物含量最高,达51.36mg/mL;特有水提的黄酮类化合物含量是普通水提含量的6.7倍.在相同剂量的情况下,蜂胶水提液和醇提液的抗炎和抗肿瘤效果差异不大甚至优于醇提.由于水提物刺激性小,易于调味,是一种极具开发潜力的提取方式.  相似文献   

13.
The aim of the article was to study the effect of different growth promoters on growth performance, carcass quality, biochemical and haematological traits and immune response of growing rabbits. A total number of 105 male growing NZW rabbits during 35–91 days of age were randomly distributed among 7 groups fed the same basal diet and submitted to different dietary treatments: the first group was unsupplemented and used as control; the other groups were supplemented respectively with bee pollen and/or propolis at 200 mg/kg BW of each and inulin and/or mannanoligosaccharides (MOS) at 35 mg/kg BW of each. Body weight gain, daily feed intake, feed conversion ratio (FCR), biochemical and haematological blood parameters, carcass characteristics, histological studies of ileum and spleen and economical efficiency were measured. Bee pollen administered alone or with propolis significantly (p < 0.01) the body weight gain and improved FCR in respect of the control group. Inulin with MOS significantly improved just FCR than the control group. Bee pollen with propolis and MOS supplemented‐groups resulted in significantly higher (7.96 and 8.41% respectively) white blood cells compared to the control group. Plasma total cholesterol was significantly higher for the MOS group in respect of the control, bee pollen, inulin and inulin with MOS supplemented‐groups. Propolis resulted in significantly higher dressed carcass percentage than the control group and higher carcass index than only bee pollen with propolis supplemented‐group. Bee pollen, in particular if in combination with propolis, could be used as a supplement in the growing rabbits during days 35–91 of age with positive effects on growth rate and feed conversion ratio.  相似文献   

14.
One hundred and twenty eight, 28‐weeks‐old Lohmann LSL hybrid layers were used in this experiment, which lasted 12 weeks to investigate the effect of propolis supplementation on the productive performance, egg quality traits and haematological variables of laying hens. All hens were randomly classified into four equal experimental groups, eight replicates (4 birds/each). Hens in group 1 were fed on a commercial diet and considered as control group, while those in groups 2, 3 and 4 were fed on the same commercial diet and supplemented with 250, 500 and 1000 mg propolis/kg diet. The obtained results revealed that daily feed consumption/hen increased insignificantly with increasing propolis level than that of the control group. Regarding the means of egg mass and egg production rate, it was observed that the laying hens fed diets containing 250 and 1000 mg propolis/kg significantly (p < 0.05) produced more and heaver egg in comparison with control group. External egg quality traits have not affected with increasing the level of propolis, while eggshell weight was significantly (p < 0.05) increased. The internal egg quality traits except albumen and yolk percentages increased significantly (p < 0.05) with increasing propolis level for treated hens as compared to those in the control. Concerning the haematological parameters, the results showed that the levels of total protein and globulin increased significantly with increasing propolis level, while cholesterol and liver enzymes were significantly decreased (p < 0.05). Heterophils count of hens in the treated groups significantly decreased, whereas the lymphocyte count significantly increased, resulting in a decreased H/L ratio than that of the control group. Thus, it could be concluded that the supplementation of 250 mg propolis/kg diet is highly recommended to improving egg production, blood constituent and haematological parameters of the commercial laying hens.  相似文献   

15.
Spontaneously Diabetic Torii (SDT) rats were discovered from SD rats and represent a confirmed spontaneous type 2 diabetes mellitus model. We investigated the effect of repeated stress in early childhood on SDT rats fed a high-fat diet, on locomotor activity and on the onset of diabetes mellitus. Regarding stress, a water immersion-restraint stress (WIRS) burden was applied 10 times every other day from 4 weeks of age. The results of the study showed, that the locomotor activity of the young SDT rats was clearly lower than that of the SD rats, and their locomotor activity was inferred to be congenitally low. In addition, the stress-burdened SDT rats showed delayed onset of diabetes mellitus and impaired glucose tolerance compared with the rats not receiving stress burden. The locomotor activity of SDT rats is less than that of SD rats, and they SDT rats are thought to have poor at spontaneous energy expenditure. On the other hand, the feeding efficiency of the WIRS-burdened SDT rats was reduced, and in comparison with the SDT rats with no WIRS burden, energy expenditure was increased; this is suggested to influence the onset of diabetes mellitus.  相似文献   

16.
以95%乙醇为溶剂,根据蜂胶提取物溶于乙醇后在一定的浓度范围内溶液的颜色与溶液的浓度成正比,选取291 nm为检测波长,检测各类蜂胶制品中的蜂胶乙醇提取物含量.  相似文献   

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