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1.
硒缺乏症是由于饲料中硒含量不足所引起的营养代谢障碍综合症。主要以骨骼、心肌及肝脏变性为基本特征。猪主要病型有仔猪白肌病、仔猪肝坏死和桑葚心等。一年四季都可发生,以仔猪发病为多,多见于冬末春初。现就猪缺硒和硒中毒及预防措施报道如下。  相似文献   

2.
低硒地区绵羊补硒的研究   总被引:1,自引:0,他引:1  
通过对绵羊食物链系统中微量元素分析和补硒效果观察表明,榆中县北部山区土壤和牧草Se含量分别为0.23mg/kg和0.03mg/kg,绵羊全血和被毛Se含量明显低于正常值。认为当地绵羊以营养不良为特征的疾病与硒缺乏有直接关系。  相似文献   

3.
硒是人和动物体具有重要生物学意义的必需微量元素。本文简要介绍了硒的生物学活性与存在形式,重点阐述了硒与病毒感染之间的关系,相信随着硒抗病毒机制研究的深入,硒将在抗病毒治疗和保障动物与人类健康中发挥更重要的作用。  相似文献   

4.
5.
微量元素硒的生物学功能   总被引:8,自引:0,他引:8  
硒是许多依赖硒的细菌和哺乳动物体内多种蛋白质的高度特异组分.笔者以硒酶与硒蛋白的生物学功能为重点,综述了微量元素硒的重要生物学功能,同时对硒与动物免疫、硒与其他矿物质元素的关系也进行了概述.  相似文献   

6.
本试验旨在研究不同水平的亚硒酸钠(SS)和酵母硒(SY)对蛋鸭产蛋性能、蛋品质、蛋硒含量和蛋硒转化率的影响,探究其在鸭蛋中的富集和消去规律。选取540只健康、产蛋性能相近的44周龄龙岩山麻蛋鸭,随机分为9组,每组6个重复,每个重复10只鸭。试验期16周,分为富集期12周和消去期4周。富集期,各组分别饲喂基础饲粮(对照组,硒含量0.15 mg/kg)及在基础饲粮中分别添加0.3、0.6、0.9和1.2 mg/kg的SS或SY(以硒计)的试验饲粮。消去期,各组均饲喂基础饲粮。结果表明:1)富集期,与对照组相比,饲粮中添加SS和SY对产蛋率、平均蛋重、日产蛋量和料蛋比均无显著影响(P>0.05),但显著提高了平均日采食量(第5~8周、第9~12周和第1~12周,P<0.05)。消去期,与对照组相比,仅饲粮中添加SY显著提高了平均日采食量(第1~2周,P<0.05)。2)与对照组相比,饲粮中添加SS和SY对蛋重、蛋形指数、蛋壳强度、蛋黄颜色、蛋壳重、蛋壳比例、蛋壳厚度均无显著影响(P>0.05),但饲粮中添加SS显著降低了蛋白高度和哈氏单位(第2、4、12周和平均值,P...  相似文献   

7.
硒中毒   总被引:4,自引:0,他引:4  
  相似文献   

8.
酵母硒对鸡蛋硒含量的影响   总被引:1,自引:0,他引:1  
为了研究酵母硒对鸡蛋硒含量的影响,试验选择30周龄京白蛋鸡3,500只,随机分为5组,每组700只,设1个对照组和4个试验组。对照组饲料中硒的含量为0.3mg/kg,以亚硒酸钠形式添加。试验组以福邦酵母硒替代亚硒酸钠,饲料中硒的含量为试验A组0.3mg/kg、试验B组0.4mg/kg、试验C组0.5mg/kg、试验D组0.6mg/kg,试验期4周。结果表明,对照组鸡蛋硒含量为0.285mg/kg,试验组鸡蛋硒含量在0.333~0.492mg/kg之间。因此,在蛋鸡饲料中添加酵母硒生产富硒鸡蛋,其添加量以0.3~0.4mg/kg最佳,饲喂1周后即可达到富硒鸡蛋的要求。  相似文献   

9.
动物硒蛋白研究进展   总被引:10,自引:2,他引:10  
硒是动物必需的微量元素 ,硒半胱氨酸是硒蛋白组分并构成硒酶的活性中心 ,而硒蛋白是硒的主要功能形式。研究发现 ,硒半胱氨酸是参入到蛋白质分子中的第 2 1种氨基酸 ,硒是唯一受基因调控的微量元素。本文对目前发现的硒蛋白种类、结构和功能进行了综述  相似文献   

10.
奶牛日粮中添加富硒酵母对乳硒和血清硒含量的影响   总被引:4,自引:4,他引:0  
通过日粮添加富硒酵母研究有机硒对泌乳奶牛乳硒含量和血清硒含量的影响。试验选择24头胎次相同,泌乳日龄、产奶量和体重相近的荷斯坦奶牛,随机分为2组,对照组和处理组均饲喂相同的TMR基础日粮,TMR基础日粮硒含量为0.33 mg/kg,处理组另补充富硒酵母,源于富硒酵母的硒为0.78 mg/kg DM,整个试验期56 d。试验结果表明,添加富硒酵母后对奶牛干物质采食量、产奶量、乳常规和乳常规产量没有显著影响,但显著提高了血清和牛奶中硒含量,分别为123.1和97.7 μg/L,与对照组相比,血清硒含量和牛奶硒含量分别提高了60.5%和194.3%。同时,在整个试验期内,血清硒含量呈上升趋势,而牛奶硒很快达到了稳定状态。  相似文献   

11.
选取80只7周龄雄性BALB/c小鼠,随机分为Ⅰ、Ⅱ、Ⅲ、Ⅳ组,每组20只,使Ⅰ、Ⅱ、Ⅲ、Ⅳ组基础日粮中硒含量达到0.045、0.1、0.4和0.8 mg/kg。结果表明:①Ⅰ组能显著降低小鼠肝脏中硒的沉积量(P<0.05);②Ⅰ组谷胱甘肽过氧化物酶1(glutathione peroxidase 1,GPx1)的mRNA相对表达量明显低于Ⅱ、Ⅲ组(P<0.05),且Ⅱ、Ⅲ组在肝脏中差异显著(P<0.05),在睾丸中差异不显著(P>0.05);③Ⅰ、Ⅲ组肝脏中谷胱甘肽过氧化物酶4(glutathione peroxidase 4,GPx4)的mRNA相对表达量差异不显著(P>0.05),但均显著低于Ⅱ组(P<0.05),而各试验组间在睾丸中差异均不显著(P>0.05);④随着日粮中硒添加量的增加,肝脏和睾丸中硫氧还蛋白还原酶2(thioredoxin reductase 2,TrxR2)的mRNA相对表达量显著提高(P<0.05)。因此,在肝脏和睾丸组织中,饲喂低硒饲料能显著降低硒的沉积量和GPx1、GPx4、TrxR2的mRNA相对表达量(P<0.05);而饲喂高硒饲料能显著降低GPx1的mRNA相对表达量(P<0.05),同时显著增加TrxR2的mRNA相对表达量(P<0.05)。提示,硒对GPx1、GPx4和TrxR2 mRNA相对表达量的调节存在组织差异性。  相似文献   

12.
The objective of this experiment was to explore the effects of different sources and levels of selenium (Se) on growth performance and tissue Se content of 10~11 months porcupine.Eighty and 10-month-old porcupine with a similar body weight were assigned to 5 groups with 8 replicates of 2 porcupines each.The porcupine were fed a basal diet without Se complementation (control group) or the basal diet adding 0.30 mg/kg Se in the form of sodium selenite (group Ⅰ),0.20 mg/kg Se in the form of yeast selenium (group Ⅱ),0.30 mg/kg Se in the form of yeast selenium (group Ⅲ) and 0.30 mg/kg mixed Se (0.15 mg/kg sodium selenite and 0.15 mg/kg yeast selenium)(group Ⅳ),respectively.The pre-test period lasted for 7 days and the trial period lasted for 45 days.The results showed that compared with the control group,there was no significant differences in the average daily feed intake (ADFI) in each group (P>0.05),the average daily gain (ADG) in groups Ⅱ and Ⅲ was significantly increased (P<0.05),the feed/gain (F/G) in group Ⅲ was significant decreased (P<0.05).Compared with the control group,the concent of Se in liver and muscle of group Ⅲ was extremely significantly increased (P<0.01),the content of Se in liver and muscle of groups Ⅱ and Ⅳ was also significantly increased (P<0.05 or P<0.01),and there was no significant difference in group Ⅰ(P>0.05).In conclusion,the basal diet supplemented with yeast selenium could improve the growth performance and increase the tissue Se concent in 10~11 months porcupine,and adding 0.30 mg/kg yeast selenium had the best effect.  相似文献   

13.
This experiment was aimed to explore the effect of different ratios of food to water of dry powder feed on growth performance,nutrient digestibility and nitrogen metabolism of growing Wusuli raccoon dogs.Thirty 11-week-old healthy Wusuli raccoon dogs with average body weight of (3.47±0.20) kg were randomly assigned into 3 groups.The Wusuli raccoon dogs were fed experimental diets with dry powder feed of ratio of food to water of 1∶2.5 (group Ⅰ),1∶3.5(group Ⅱ),1∶4.5 (group Ⅲ),respectively.The pre-test period lasted for 7 days and the trial period lasted for 67 days.The results showed that the average daily feed intake of each week from 11,12 to 13 weeks in groupⅠ was significantly less than that in groups Ⅱ and Ⅲ (P<0.05),the average daily feed intake of each week from 14,15 to 20 weeks was no significant difference among all groups (P>0.05).The total intake in group Ⅰ was significantly less than that in group Ⅱ (P<0.05).The average daily gain of each week from 15 to 17 weeks in group Ⅲ was significantly higher than that in group Ⅰ (P<0.05),while the average daily gain,total weight and the rate of feed intake to body gain in other week-old were no significant differences among all groups (P>0.05).The protein digestibility,fat digestibility and dry matter digestibility were no significant differences among all groups (P>0.05).The amount of urine in group Ⅲ was extremely significantly higher than that in groups Ⅰ and Ⅱ (P<0.01).The nitrogen intake,fecal nitrogen,urine nitrogen,nitrogen deposition,net protein utilization and biological value of protein were no significant differences among all groups (P>0.05).In conclusion,the appropriate ratios of food to water of dry powder feed of growing Wusuli raccoon dogs was 1∶3.5 to 1∶4.5.  相似文献   

14.
本试验旨在研究饲粮中硒添加水平对产蛋高峰期临武鸭产蛋性能、蛋品质、血清抗氧化指标和蛋硒含量动态变化的影响。试验选用29周龄体况良好、产蛋率接近的正处于产蛋高峰期的临武鸭200只,随机分为5组,每组5个重复,每个重复8只。对照组饲喂基础饲粮(不额外补充硒源,实测硒含量为0.15 mg/kg)45 d,Ⅰ组、Ⅱ组、Ⅲ组、Ⅳ组分别在基础饲粮中以酵母硒形式添加0.10、0.20、0.40、0.80 mg/kg的硒,饲喂35 d添加硒饲粮后改喂基础饲粮10 d。结果显示:1)饲粮中硒添加水平对蛋鸭产蛋性能和蛋品质各指标均无显著影响(P0.05)。2)与对照组和Ⅰ组相比,饲粮中添加0.40和0.80 mg/kg的硒可以显著提高蛋鸭血清中硒和谷胱甘肽(GSH)含量以及超氧化物歧化酶(SOD)和谷胱甘肽过氧化物酶(GSH-Px)活性(P0.05),显著降低血清中丙二醛(MDA)含量(P0.05)。3)随试验天数的增加,对照组和Ⅰ组蛋硒含量无显著变化(P0.05),而Ⅱ组、Ⅲ组、Ⅳ组蛋硒含量均呈现先升高后降低的趋势,且均在试验第9天达到峰值。试验第7、9、13、17、21、28和35天,Ⅱ组、Ⅲ组、Ⅳ组蛋硒含量显著高于对照组和Ⅰ组(P0.05);停喂添加硒饲粮的第1~4天,Ⅱ组、Ⅲ组、Ⅳ组蛋硒含量仍显著高于对照组(P0.05);停喂添加硒饲粮的第5~8天,Ⅲ组和Ⅳ组蛋硒含量显著高于对照组(P0.05);停喂添加硒饲粮的第9天,各试验组蛋硒含量均衰减至与对照组相同水平(P0.05)。由此可见,饲粮中添加不同水平的酵母硒形式的硒对产蛋高峰期临武鸭的产蛋性能和蛋品质均无不良影响。饲粮中添加0.40和0.80 mg/kg酵母硒形式的硒可以提高产蛋高峰期临武鸭的蛋硒含量、血清硒含量和抗氧化能力,延长蛋硒的存留时效。综合考虑各因素,产蛋高峰期临武鸭饲粮中硒(以酵母硒形式添加)的适宜添加水平为0.40 mg/kg。  相似文献   

15.
研究注射不同水平黄芪多糖(APS)对蛋鸡免疫功能及脾脏IFN-γ基因表达的影响。试验组(Ⅱ、Ⅲ、Ⅳ组,分别为低、中、高剂量组)与对照组(Ⅰ组)比较,Ⅱ、Ⅲ组血清中IgG、IgA、IgM含量分别提高54.0%(P〈0.05)、72.7%(P〈0.01),5.56%(P〉0.05)、1.36%(P〉0.05),24.96%(P〉0.05)、77.13%(P〈0.05);Ⅲ组血清C3含量和Ⅱ组血清C4含量提高显著;Ⅳ组对各免疫指标无显著影响(P〉0.05)。免疫后21d,Ⅲ组对应的鸡外周血T淋巴细胞增殖能力和禽流感抗体效价均显著高于对照组(P〈0.05)。Ⅲ组中脾脏INF-γmRNA的表达量显著高于其他组(P〉0.05)。结果表明,黄芪多糖对蛋鸡有显著的免疫增强作用。注射不同计量的黄芪多糖剂能不同程度影响蛋鸡血清中相关的免疫指标、外周淋巴细胞的增殖、禽流感HI抗体效价及脾脏IFN-γ基因mRNA的水平。其中,以0.6mL/羽剂量效果为最佳。  相似文献   

16.
This study was to investigate the effects of different proportions of wheat and fermented sesame meal on growth performance,meat quality and serum biochemical indexes in broilers under the condition of adding exogenous enzymes in the diet.A total of 520 21-day-old broilers (fast)with an average body weight of (330±10)g were randomly assigned to 5 groups with 4 replicates in each group and each replicate contained 26 broilers. Broilers in the 5 groups were fed experimental diets containing 0 (control group),20% wheat +5% fermented sesame meal (group Ⅰ),40% wheat +10% fermented sesame meal (group Ⅱ),20% wheat + soybean meal (group Ⅲ) and 40% wheat + soybean meal (group Ⅳ),respectively.The pre-test period lasted for 3 days and the trial period lasted for 34 days.The results showed that compared with the control group,the ADG in groups Ⅰ,Ⅱ,Ⅲ and Ⅳ was significantly decreased by 9.40%,7.15%,8.87%,5.46% (P<0.05),respectively,while the ADFI and F/G showed no significant differences (P>0.05).There were no significant differences on meat quality among all experimental groups(P>0.05), respectively, but group Ⅱ had better meat quality than others.Compared with the control group,the content of alanine aminotransferase in serum in groups Ⅲ, Ⅳ was significantly decreased by 30.10%,25.36% (P<0.05),but there were no significant differences in the contents of total protein,urea nitrogen and aspartate aminotransferase in serum in all experimental groups(P>0.05).In conclusion,under the experimental conditions,adding appropriate proportions of wheat and sesame meal could replace part of the corn and soybean meal in the diet,and the better supplementation level of wheat and fermented sesame meal was 40% and 10%,respectively.  相似文献   

17.
The study was conducted to determine the effects of different levels of selenium yeast(SeY, added as selenium content) on growth performance and some biochemical indexes in Jinding laying ducks under high temperature (29-35℃). 144 Jinding laying ducks of rearing period (10-16 weeks old) were divided into 4 groups, control group, experimental groups Ⅰ,Ⅱ and Ⅲ, supplemented with 0, 0.15, 0.45 and 0.75 mg/kg Se, respectively. The results showed that compared with the control group, the addition of SeY to the diets could significantly increase the average daily feed intakes (ADFI) of ducks at 14-16 weeks old (P<0.05); The body weights of ducks in group Ⅰ at 13-15 weeks old were significant higher than that in the control group (P<0.05),and the body weight at 16 weeks old was higher than the other three groups significantly (P<0.05),there was no significant difference between the body weight and standard body weight at 16 weeks old in group Ⅰ(P>0.05), but the body weights of other three groups were extremely significantly lower than the standard weight (P<0.01); There was no significant difference among the four groups for feed to gain ratios (F/G), while the group Ⅰ was the lowest; AST activities of group Ⅰ were significantly lower than group Ⅱ(P<0.05), LDH activities of groups Ⅰ,Ⅱ and Ⅲ were lower than the control group significantly (P<0.05), and LDH activities of groupⅠ were lower than groups Ⅱ and Ⅲ significantly (P<0.05). TCH concentrations of groups Ⅰ and Ⅱ were higher than group Ⅲ significantly (P<0.05). It is concluded that the addition of 0.15 mg/kg of Se (added as SeY) could obviously improve the growth performance of the laying ducks in reared cages, protect the function of liver, promote the TCH concentrations of duck serum.  相似文献   

18.
试验旨在观察钼暴露对雌性小鼠肾脏脂质过氧化损伤及Smac蛋白表达的影响。选用60只35日龄健康雌性昆明小鼠,随机分成3组(对照组、补钼Ⅰ组、补钼Ⅱ组),分别饮用含钼浓度为0、200、400 mg/L的去离子水,连续染毒90 d后取样检测肾脏组织SOD活性和MDA含量,免疫组化法检测肾脏组织Smac蛋白表达。与对照组比较,补钼Ⅰ组SOD活性显著降低(P<0.05),补钼Ⅱ组SOD活性极显著降低(P<0.01);补钼Ⅱ组MDA含量较对照组显著升高(P<0.05)。补钼Ⅰ组、补钼Ⅱ组小鼠肾皮质Smac蛋白表达极显著高于对照组(P<0.01)。结果表明,钼暴露对小鼠肾脏能产生脂质过氧化损伤,钼可以通过上调线粒体促凋亡蛋白Smac蛋白表达参与肾脏的损伤过程。  相似文献   

19.
本试验旨在研究不同剂量硒蛋白粉对大鼠血常规指标及血液生化指标的影响。选择平均体重为70 g的健康清洁级SD大鼠80只,随机分为4组,每组2个重复,每个重复10只,雌、雄各半。对照组饲喂基础日粮,低、中和高剂量组分别饲喂添加3.5、7和10.5 mg/kg硒蛋白粉的日粮(其含量以硒计),试验期30 d。结果表明,低、中和高剂量组大鼠血常规指标与对照组相比差异均不显著(P>0.05);低、中和高剂量组大鼠血清中血糖、总蛋白含量与对照组相比差异均不显著(P>0.05),低剂量组大鼠血清中甘油三酯、低密度脂蛋白含量均显著低于对照组(P<0.05);中剂量组大鼠血清中白蛋白/球蛋白及甘油三酯、低密度脂蛋白含量均显著低于对照组(P<0.05),而谷丙转氨酶和谷草转氨酶水平均显著高于对照组(P<0.05);高剂量组大鼠血清中白蛋白、白蛋白/球蛋白、甘油三酯、低密度脂蛋白含量均显著低于对照组(P<0.05),而球蛋白、谷丙转氨酶、谷草转氨酶、尿素氮、肌酐、高密度脂蛋白含量均显著升高(P<0.05)。综上所述,不同剂量硒蛋白粉对大鼠血常规指标无不良影响,低剂量硒蛋白粉除具有降低大鼠血脂作用外对大鼠其他血液生化指标均无不良影响,中、高剂量硒蛋白粉对大鼠的部分血液生化指标有一定影响。  相似文献   

20.
本文旨在研究酵母硒、黄芪多糖及其复合剂对半番鸭生长性能、肉品质和抗氧化能力的影响。从同一批饲养的22日龄半番鸭中挑选出体重相近的144只,随机分为4组,每组3个重复,每个重复12只鸭,试验期为49 d。采用2×2因子水平设计,对照组饲喂基础饲粮,试验Ⅰ组饲喂基础饲粮+0.3%酵母硒,试验Ⅱ组饲喂基础饲粮+300 mg/kg黄芪多糖,试验Ⅲ组饲喂基础饲粮+复合剂(300 mg/kg黄芪多糖+0.3%酵母硒)。试验期间测定生长性能指标,并于70日龄每组随机选择12只(每重复4只)进行屠宰,测定其胸肌肉品质和抗氧化指标。结果显示:1)试验Ⅰ组和试验Ⅱ组平均日增重、平均日采食量及料重比与对照组相比差异均不显著(P0.05);试验Ⅲ组平均日增重显著高于对照组(P0.05),平均日采食量和料重比与对照组无显著差异(P0.05)。2)与对照组相比,试验Ⅰ组、试验Ⅱ组和试验Ⅲ组24 h p H均显著或极显著提高(P0.05或P0.01),48 h滴水损失率、蒸煮损失率、剪切力显著或极显著降低(P0.05或P0.01);试验Ⅲ组肉色红度(a*)值显著提高(P0.05);试验Ⅱ组和试验Ⅲ组肉色黄度(b*)值均显著降低(P0.05)。3)试验Ⅰ组、试验Ⅱ组和试验Ⅲ组24~120 h的超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-Px)活性及总抗氧化能力(T-AOC)均显著或极显著高于对照组(P0.05或P0.01);试验Ⅰ组、试验Ⅱ组48~120 h和72~120 h的丙二醛(M DA)含量分别显著或极显著低于对照组(P0.05或P0.01),试验Ⅲ组24~120 h的MDA含量极显著低于对照组(P0.01)。随储存时间延长,各组SOD、GSH-Px活性和T-AOC均呈下降趋势,MDA含量则呈上升趋势,但3个试验组各抗氧化指标的变化速度比对照组缓慢。4)酵母硒和黄芪多糖对肌肉24 h p H、剪切力、24~120 h的SOD活性、48~120 h的GSH-Px活性、120 h的M DA含量有显著或极显著交互作用(P0.05或P0.01)。由此可见,酵母硒、黄芪多糖均可改善半番鸭肌肉品质和提高抗氧化能力,降低脂质过氧化程度,有效延长货架期,且二者对于肌肉抗氧化、p H和嫩度改善均具有明显的协同效应。  相似文献   

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