共查询到18条相似文献，搜索用时 156 毫秒
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氟苯尼考与多西环素复方制剂对鸡大肠杆菌病的疗效试验 总被引：1，自引：0，他引：1
采用氟苯尼考与多西环素复方制剂对人工诱发的鸡大肠杆菌病进行治疗。试验结果表明,人工诱发的鸡大肠杆菌疾病模型是成功的,且治疗试验结果显示:该制剂可溶性粉3个剂量组、药物对照组死亡率均极显著低于感染对照组(P<0.01),治愈率极显著高于感染对照组(P<0.01);高、中剂量组治愈率与死亡率无统计学差异(P>0.05),但均显著高于多西环素对照组(P<0.05),而低剂量组与多西环素对照组比较差异不显著(P>0.05)。各用药组鸡相对增重率与感染对照组相比较差异极显著(P<0.01),而各用药组之间相比较,差异不显著(P>0.05)。说明该制剂在临床中有一定的实用价值,值得推广使用。 相似文献
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为了探究常山、槟榔和甘草3味中草药制成的复方制剂预防柔嫩艾美耳球虫感染鸡的效果,试验通过建立鸡柔嫩艾美耳球虫感染模型,将复方制剂按0.25 g/kg、0.5 g/kg、1 g/kg和2 g/kg 4个剂量组对感染鸡只进行饲喂。通过存活率、相对增重率、盲肠病变、卵囊值以及抗球虫指数等指标来评价复方制剂预防鸡感染柔嫩艾美耳球虫的效果。试验结果显示,复方制剂中高剂量组的效果为161,抗球虫药效达到中等,复方制剂低剂量组、中剂量组和高剂量组的药效分别为149、152和153,均达到了抗球虫的标准。 相似文献
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为筛选具有显著治疗犬蠕形螨的中药制剂,试验将中药小茴香、蛇床子、羊蹄根采用水煮醇沉及蒸馏等提取方法制备成中药制剂犬螨灵,并观察其对犬蠕形螨的疗效。将犬螨灵设为高、中、低3个浓度,其生药含量分别为2.0、1.0和0.5 g/mL,采用点滴法进行体外抑杀蠕形螨试验,在此基础上对12只接种蠕形螨的试验犬进行治疗试验,为验证治疗效果,对临床上已确诊的45只患有蠕形螨的病犬分3组进行临床治疗试验。结果显示,中药犬螨灵3种剂量均有较强的体外抑杀螨虫作用,高剂量组作用后4 h即可完全抑杀蠕形螨,1%伊维菌素对照组则为作用后8 h;高剂量组在治疗3周后,患处有大量新毛生长,红疹结节和皮屑消失,患处皮肤已痊愈,1%伊维菌素治疗组患犬皮肤好转,仅有少量新毛生长,不能达到痊愈标准;高、中剂量组皮肤刮取物螨虫数量平均比例及停药1个月后复发率均为0,1%伊维菌素治疗组皮肤刮取物螨虫数量平均比例及停药1月后的复发率分别为10.63%和9.17%。高剂量中药犬螨灵与1%伊维菌素两种药物联合治疗组,对临床上患病犬进行3周治疗,其虫卵平均转阴率、治愈率与平均治愈天数分别为100.00%、93.33%和19.56 d,其效果均优于中药犬螨灵与1%伊维菌素单独治疗组。结果表明,高剂量自制中药制剂犬螨灵对犬蠕形螨体外抑杀作用、接种蠕形螨试验犬与临床自然感染病例均有显著的治疗效果,优于1%伊维菌素对照组,犬螨灵作为中药杀螨虫制剂具有较好的市场开发前景。 相似文献
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为评价复方阿莫西林乳房注入剂对泌乳期奶牛临床型乳房炎的治疗效果,在甘肃某两个牛场选择70头自然发生的临床型乳房炎奶牛进行临床试验。将患病奶牛随机分为试验组(n=36头)和对照组(n=34头)。试验用药和对照用药分别为郑州百瑞动物药业有限公司和齐鲁动物保健品有限公司提供的复方阿莫西林乳房注入剂。每个感染乳区注入3 g药物,每12 h注射1次,连续用药3 d。在用药前、停药后7 d及14 d采集各组奶牛的奶样进行细菌学检测及乳汁体细胞计数。通过临床观察、细菌清除率及体细胞计数变化对临床疗效进行评价。停药后14 d,试验组和对照组的临床治愈率分别为58.3%和61.8%,细菌总清除率分别为94.12%和93.55%。两组奶样中的SCC在治疗后均显著下降(P<0.01)。两组临床疗效无统计学差异(P>0.05),表明试验用药对奶牛临床型乳房炎具有良好的治疗效果。 相似文献
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为了评价米尔贝肟对临床自然感染疥螨犬的治疗效果,选用自然感染疥螨犬65例,随机选择5条服用伊维菌素,另外60条随机分为3组,分别服用高剂量(2g/kg体重)、中剂量(1g/kg体重)、低剂量(0.5g/kg体重)的米尔贝肟。给药后2、14、28、42d和56d,刮取皮屑,检查螨虫和虫卵,同时观察临床症状。试验结束时米尔贝肟高剂量组、伊维菌素组的无螨虫犬的比例和螨虫的下降率均为100%,临床症状如红疹、结痂、过度角化等现象均消失,所有动物毛发都开始大范围重生;米尔贝肟中、低剂量组结果稍差。米尔贝肟按2g/kg体重剂量,每周1次,连续用药3周,给药对自然感染疥螨病犬有很好的治疗效果。 相似文献
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A comparative field trial of cephalonium and cloxacillin for dry cow therapy for mastitis in Australian dairy cows 总被引：2，自引：0，他引：2
OBJECTIVE: To investigate and compare the therapeutic efficacy of dry cow agents containing either cephalonium or cloxacillin within Australian dairy herds. DESIGN: A treatment-control trial. METHODS: Milk from infected quarters of cows with high somatic cell counts in milk on eight Australian dairy farms was cultured to identify bacterial pathogens. Cows were randomly assigned to treatment groups and one group was treated with cephalonium at drying off and the other group was treated with cloxacillin at drying off. Milk samples from infected quarters were collected immediately after calving and were cultured for pathogens. The effect of treatment on bacteriological cure was examined and somatic cell counts from infected cows from the first two herd tests after calving were examined for a treatment effect. On four farms, milk samples were collected for culture from all cases of clinical mastitis identified within the first 7 days after calving. The effect of treatment upon incidence of clinical mastitis after calving was examined. RESULTS: There was no significant difference between treatments on quarter cure rates for new infections, for chronic infections and for infections with Staphylococcus aureus, Streptococcus agalactiae and Streptococcus uberis. Infected quarters treated with cephalonium had a significantly higher cure rate than quarters treated with cloxacillin when Corynebacterium bovis and Staphylococcus epidermids were included as pathogens combined (80.3% versus 70.7%). There was no significant difference between the treatments on somatic cell counts of infected cows at the first two herd tests after calving. There was no difference between treatments on the incidence of clinical mastitis in the first 7 days after calving. 相似文献
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Roy J Bédard C Moreau M 《The Canadian veterinary journal. La revue veterinaire canadienne》2011,52(3):277-282
A blinded randomized study was conducted on 24 cats to confirm the presence of bacterial and/or fungal secondary infections associated with otoacariasis and to verify the efficacy of Oridermyl, an acaricidal/antibiotic/antifungal/anti-inflammatory ointment, for treatment of the primary infestation and secondary infections. Sixteen cats were treated once daily for 10 d; 4 cats were not treated and 4 were treated with a placebo ointment. On Days 0 and 10, ears were swabbed for counts of bacteria and yeasts, for bacterial culture and sensitivity, and examined for determination of the degree of clinical otitis. Auricular secretions were removed for mite counts on Day 10, except for 8 treated cats that were done on Day 30. There was a high number of bacteria and yeasts in most cats and Oridermyl treatment significantly decreased those numbers. Staphylococci were the most frequently isolated bacteria. No live ear mites were found in cats treated with Oridermyl or the placebo ointment. 相似文献
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家蝇抗菌肽提取及对鸡大肠杆菌病药效试验 总被引：7，自引：0，他引：7
体外抑菌试验结果证明抗菌肽对O1型血清大肠杆菌的药敏抑菌圈直径为19.3±0.32mm,以O1型大肠杆菌感染14日龄岭南黄肉用雏鸡,24 h后分别用抗菌肽高、中、低剂量及环丙沙星混饮给药,以比较其疗效。通过临床观察、尸体解剖、细菌检验结果表明,试验药物组与感染对照组差异极显著(P<0.01),即试验药物对鸡大肠杆菌病有良好疗效;抗菌肽高、中剂量与环丙沙星疗效相当(P>0.05),且不影响鸡只的正常增重(P>0.05)。 相似文献
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为了观察盐酸多西环素对急性期犬埃立克体病的治疗效果,对人工感染埃立克体的比格犬进行了盐酸多西环素的治疗试验。采集比格犬感染前及治疗前后的血液样本,测定血常规及各项血生化指标,并对测定结果作统计学处理。血常规检测发现与治疗前相比,治疗后RBC、WBC、HGB、PLT、MPV、NEU-TRO、LYM、MONO和RDW显著升高;HCT、MCV、MCH和MCHC无明显变化;血生化检测发现,与治疗前相比,治疗后ALT和AST显著降低,ALB显著升高;治疗后与感染前相比,血常规和血生化各项均没有显著变化。进一步证实了盐酸多西环素对犬埃立克体病急性期病例具有良好的治疗效果。 相似文献
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Sickafoose L Hosgood G Snook T Westermeyer R Merchant S 《Veterinary therapeutics : research in applied veterinary medicine》2010,11(2):E1-E13
This double-blinded noninferiority clinical trial evaluated the use of oral fluconazole for the treatment of Malassezia dermatitis in dogs by comparing it with use of an accepted therapeutic agent, ketoconazole. Dogs presenting with Malassezia dermatitis were treated with either fluconazole or ketoconazole in addition to cephalexin for concurrent bacterial dermatitis. Statistically significant improvements in cytologic yeast count, clinical signs associated with Malassezia dermatitis, and pruritus were seen with both antifungal treatments. There was no statistical difference between the treatments with regard to the magnitude of reduction in these parameters. These results suggest that fluconazole is at least as effective as ketoconazole for the treatment of dogs with Malassezia dermatitis. 相似文献
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复方氟康唑软膏对家兔皮肤的刺激性观察 总被引：1，自引：1，他引：0
为研究复方氟康唑软膏对皮肤的刺激性,以复方制霉菌素软膏为对照药物,将8只家兔随机分为完整性皮肤试验组和破损性皮肤试验组,采用左右侧自身对比,观察复方氟康唑软膏对家兔的皮肤刺激性。结果显示,复方氟康唑软膏与复方制霉菌素软膏对完好皮肤与损伤皮肤的平均反应分值无明显差异,其中完好皮肤组家兔在给药后不同时间对两种药物的平均反应分值均低于0.5分;破损皮肤组家兔在给药后1 h和24 h对两种药物的平均反应分值均大于0.5分,但低于3.0分,给药48 h后家兔对两种药物的平均反应分值均低于0.5分。试验过程中无其他不良反应。试验表明,复方氟康唑软膏对完整皮肤无刺激性,对破损皮肤有轻度刺激性。 相似文献