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Rabies is an enzootic viral disease widespread throughout the world. Although it is a vaccine-preventable disease, the annual number of human deaths caused by rabies is estimated to be 32,000 in Asia. Phylogenetic analysis based on sequence data of the partial N gene of rabies viruses in Asia has shown that the viruses are divided into five genogroups, distributed in Middle East, South Asia, South East Asia, Malay, and Arctic regions. The genetic relationships among these rabies viruses agree basically with the results of previous studies. Meanwhile, new types of vaccines are being developed by applying gene manipulation techniques to rabies virus in order to overcome the disadvantages of current vaccines. This article reviews the molecular epidemiology of rabies in Asia and progress made in the development of new-generation rabies vaccines with the goal of elimination or control of rabies in Asia. 相似文献
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H Fischman 《Journal of the American Veterinary Medical Association》1984,184(5):532-533
Arteriosclerosis caused by Dirofilaria immitis adult parasites was diagnosed in a 20-month-old Quarter horse stallion that died from cantharidin toxicosis. Microscopically, the pulmonary vascular changes were typical of those described as "proliferative endarteritis" in D immitis-infected dogs. 相似文献
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Distribution of oral rabies vaccine (ORV) is an effective but costly strategy to control raccoon rabies. Because of high costs, ORV for raccoon rabies in the U.S. has been limited primarily to epizootic areas, leaving extensive raccoon rabies regions without any ORV intervention. Several cost scenarios for ORV application in raccoon rabies enzootic and epizootic regions were modelled in New York State to obtain estimated costs of ORV baits per scenario and potential savings compared with a uniform ORV baiting strategy. These cost scenarios modelled at the census tract, level the application of ORV baits at different densities according to levels of risk defined by the observed number of raccoon rabies cases per km2 and the expected number of cases per km2 estimated with a Poisson regression model. Bait purchase costs were lower using the modelled cost scenarios than a uniform baiting strategy, for both the NYS enzootic region and the Long Island epizootic zone. The proportion of savings for the NYS enzootic region was 29.57%, and the proportion of savings for the Long Island epizootic zone was 38.9%. Use of these cost scenarios to determine bait distribution by rabies risk level should be considered to maximize efficacy and reduce costs of ORV interventions. 相似文献
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狂犬病(Rabies),又名恐水症(Hydrophobia),俗称疯狗病,是由狂犬病病毒(Rabies Virus,RV)引起的人和所有温血动物共患的一种急性直接接触性传染病。在《中华人民共和国传染病防治法》中被定为乙类传染病,严重威胁着人类健康。根据世界卫生组织(WHO)统计资料报道,全世界每年约有5万人死于狂犬病。我国著名科学家、中国科学院院士吴阶平教授在中华医学会第21次全国代表大会上所作的《开拓进取、迎接21世纪》的报告中,把狂犬病、病毒性肝炎、癌症和吸毒列为我国21世纪重点防治的疾病。目前,人狂犬病多见于亚洲的印度、泰国、斯里兰卡、柬埔… 相似文献
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Nonfatal canine rabies 总被引：5，自引：0，他引：5
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Recovery of pigs from rabies 总被引：4，自引：0，他引：4
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