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1.
In order to prove the effects of mass application of oral erysipelas vaccine via drinking water, in a farrow-to-finish production unit in Croatia, the growing-finishing animals were divided into 3 groups and treated as follows:--Group 1 (n=199) was vaccinated intramuscularly against swine erysipelas at 1 week and 3 weeks after arrival in the growing-finishing facility with a swine erysipelas bacterin.--Group 2 (n=199) were vaccinated at the same time with an avirulent culture of Erysipelothrix rhusiopathiae oral vaccine through drinking water.--Group 3 (n=200) was not vaccinated. Animals with clinical signs of swine erysipelas, chronic progressive arthritis at slaughter, mortality, average daily weight gain during the growing-finishing phase were evaluated. None of the pigs in the groups 1 and 2 showed clinical signs typical for acute swine erysipelas. Twenty-four of the pigs (12 %) in group 3 had pyrexia and skin lesions typical for swine erysipelas. Fifteen pigs in group 1, 13 pigs in group 2, and 63 pigs in group 3 had chronic progressive arthritis (group 1 and 2 vs. group 3: P < 0.01). No significant differences in mortality were recorded between the groups. Group 1 and 2 had higher (P < 0.05) average daily weight gains compared with the group 3. 相似文献
2.
The aim of the present study was to evaluate the effect of oral vaccination against Lawsonia intracellularis (LI) on growing-finishing pig's performance. In a large Hungarian growing-finishing pig production unit, pigs with positive LI status were randomly divided into 2 groups and treated as follows: Group one: growing pigs (n = 4112) were LI vaccinated with an avirulent oral live vaccine (Enterisol Ileitis Boehringer Ingelheim Vetmedica, Inc., St. Joseph, USA). Group two: growing pigs (n = 4188 pigs) have not received LI vaccination. Culling and mortality rates, reasons for culling or mortality, and average daily weight gain were evaluated. Porcine proliferative enteropathy (PPE) caused culling and mortality rates were lower (0.2 % vs. 14.9 %, P < 0.001), and vaccinated pigs had lower none-PPE caused culling and mortality rates compared with the non-vaccinated ones (1.4 vs. 2.6 %, P > 0.05). While systemic infections and social stress or cannibalism related culling or mortality were significantly (P < 0.05) lower in vaccinated than in non-vaccinated pigs, reasons for culling or mortality due to non-LI caused diseases were non-significantly different between the vaccinated and non-vaccinated pigs. Average daily weight gain was higher (P < 0.05) in the LI vaccinated group of animals compared with the non-vaccinated ones (780 +/- 45 g vs. 660 +/- 71 g). The present results indicate that that LI vaccination does not only prevent PPE, but might result in more resistance and tolerance against other infectious and management caused losses. 相似文献
3.
A herd of pigs infected with Mycoplasma hyopneumoniae was used in a double-blind randomised trial to assess the effectiveness of three control strategies against chronic respiratory disease in growing-finishing pigs. One group of 61 pigs received 220 ppm lincomycin hydrochloride in the feed from day 71 to day 91, a second group was vaccinated against M. hyopneumoniae at four and 28 days of age, and a third group received both treatments; a fourth group was left untreated as a control. Throughout the nursery-finishing period (day 29 to slaughter) the average daily weight gain and feed conversion rate of all the treated groups were slightly better than in the controls, but there were no significant differences between them. There were no significant differences between the treated groups in terms of clinical signs, serology, pathology or mortality, which was very low throughout the trial. 相似文献
4.
Comparison of the efficacy of a subunit and a live streptomycin-dependent porcine pleuropneumonia vaccine 总被引：3，自引：0，他引：3
Tumamao JQ Bowles RE van den Bosch H Klaasen HL Fenwick BW Storie GJ Blackall PJ 《Australian veterinary journal》2004,82(6):370-374
Objective To evaluate the efficacy of two new-generation porcine pleuropneumonia vaccines when challenged with Australian isolates of Actinobacillus pleuropneumoniae of serovars 1 and 15.
Design The Porcilis APP vaccine and an experimental streptomycin-dependent strain of A pleuropneumoniae were evaluated in a standardised pen trial. Each vaccine/challenge group consisted of 10 pigs.
Results With the serovar 1 challenge, the Porcilis APP vaccine and the live vaccine, compared with the control group, gave significant protection in terms of clinical signs, lung lesions, re-isolation scores and average daily gain (ADG) postchallenge. Only the Porcilis APP vaccine provided significant protection against mortality. In the serovar 15 challenged pigs, the only significant difference detected was that the Porcilis APP vaccinated pigs had a better postchallenge ADG than the controls. None of the Porcilis APP vaccinated pigs showed signs of depression postvaccination and none were euthanased after challenge with either serovar 1 or 15. The pigs vaccinated with the live vaccine showed obvious depression after each vaccination and a total of 3 pigs were euthanased after challenge (one with serovar 1 and two with serovar 15).
Conclusions Both of the vaccines provided significant protection against a severe challenge with serovar 1 A pleuropneumoniae. Neither vaccine was effective against a serovar 15 A pleuropneumoniae challenge. There was evidence that the Porcilis APP vaccine did provide some protection against the serovar 15 challenge because the ADG, after challenge of pigs given this vaccine, was greater than the control pigs. 相似文献
Design The Porcilis APP vaccine and an experimental streptomycin-dependent strain of A pleuropneumoniae were evaluated in a standardised pen trial. Each vaccine/challenge group consisted of 10 pigs.
Results With the serovar 1 challenge, the Porcilis APP vaccine and the live vaccine, compared with the control group, gave significant protection in terms of clinical signs, lung lesions, re-isolation scores and average daily gain (ADG) postchallenge. Only the Porcilis APP vaccine provided significant protection against mortality. In the serovar 15 challenged pigs, the only significant difference detected was that the Porcilis APP vaccinated pigs had a better postchallenge ADG than the controls. None of the Porcilis APP vaccinated pigs showed signs of depression postvaccination and none were euthanased after challenge with either serovar 1 or 15. The pigs vaccinated with the live vaccine showed obvious depression after each vaccination and a total of 3 pigs were euthanased after challenge (one with serovar 1 and two with serovar 15).
Conclusions Both of the vaccines provided significant protection against a severe challenge with serovar 1 A pleuropneumoniae. Neither vaccine was effective against a serovar 15 A pleuropneumoniae challenge. There was evidence that the Porcilis APP vaccine did provide some protection against the serovar 15 challenge because the ADG, after challenge of pigs given this vaccine, was greater than the control pigs. 相似文献
5.
本试验旨在研究发酵小麦制酒精沼渣对生长肥育猪生长性能、血清生化指标和肉品质的影响。选用128头体重为40 kg左右的"杜×长×大"杂交猪,根据性别随机分为4个组,每组4个重复,每个重复8头猪(公母各占1/2)。对照组饲喂基础饲粮,试验1、2和3组饲粮分别用5%、10%和15%发酵小麦制酒精沼渣替代基础饲粮中的部分豆粕。预试期7 d,试验期60 d,分为前期(1~30 d)和后期(31~60 d)2个阶段。结果表明:1)试验前期,各组生长肥育猪的生长性能指标均无显著差异(P0.05)。试验后期,试验1、2和3组的平均日增重均显著高于对照组(P0.05),分别增加了16.47%、25.88%和20.00%,且试验2组的平均日增重极显著高于对照组(P0.01);试验1、2和3组的平均日采食量均显著高于对照组(P0.05);而各组的料重比无显著差异(P0.05)。试验全期,试验2和3组的平均日增重显著高于对照组(P0.05)。2)饲粮中添加发酵小麦制酒精沼渣对生长肥育猪的血清谷丙转氨酶(ALT)、谷草转氨酶(AST)活性以及总蛋白(TP)、尿素氮(UN)含量均无显著影响(P0.05)。3)饲粮中添加发酵小麦制酒精沼渣对生长肥育猪背最长肌的p H1 h、亮度(L*)、红度(a*)、黄度(b*)、滴水损失、蒸煮损失、剪切力、硬度、弹性、内聚性、回复性以及肌内脂肪含量均无显著影响(P0.05)。试验1和2组背最长肌中苏氨酸、赖氨酸、脯氨酸、非必需氨基酸和总氨基酸含量显著高于对照组和试验3组(P0.05),试验2组的谷氨酸、试验1组的甘氨酸以及试验1和2组的丝氨酸、丙氨酸含量均显著高于对照组(P0.05)。饲粮中添加发酵小麦制酒精沼渣对生长肥育猪背最长肌中脂肪酸含量均无显著影响(P0.05)。结果提示,饲粮中添加5%和10%发酵小麦制酒精沼渣能提高生长肥育猪的平均日增重和平均日采食量,并可提高部分鲜味氨基酸的含量,进而改善肉的风味。 相似文献
6.
试验共使用８４头杜长大试猪,研究按理想可消化氨基酸模式利用不同蛋白源配制的基础饲粮对生长肥育猪生产性能的影响。试验结果：豆粕＋鱼粉、豆粕、豆粕＋棉粕＋菜粕３种不同蛋白源构成的基础饲粮,无论生长期、肥育期还是生长肥育全期日增重差异均不显著,采食量和饲料／增重比也很接近,肥育猪的瘦肉率和背膘厚等指标无大的差异。但豆粕＋棉粕＋菜粕日粮较豆粕＋鱼粉日粮千克增重饲料成本低４．６３％。表明,按理想可消化氨基酸 相似文献
7.
Yamamoto K Takagi M Endoh YS Kijima M Takahashi T 《Journal of veterinary medicine. B, Infectious diseases and veterinary public health》2000,47(6):453-460
To investigate the influence of antibiotics used as feed additives on the immune response to erysipelas live vaccine, the pig inoculation test was applied. Avilamycin, oxytetracycline quaternary salt, enramycin, virginiamycin and tylosin phosphate were selected as test antibiotics. Five experimental feeds containing each antibiotic at the highest concentration permitted for feed additives in Japan, and the basal diet lacking antibiotics were examined. Twenty-nine pigs were divided into six groups. At first all the groups were fed with the antibiotic-free basal diet for 7 days, and then each group received the experimental feeds. On the 14th day after feeding with test feeds all the pigs, except for one control pig in each group, were immunized with the vaccine and all the pigs were then challenge-exposed to a virulent strain of Erysipelothrix rhusiopathiae 14 days after vaccination. The clinical response was observed every day for 14 days. In all the groups, most of the vaccinated pigs did not develop any clinical signs of acute erysipelas after the challenge exposure, whereas non-vaccinated control pigs died or showed severe generalized erythema with profound depression and anorexia. No differences in the protection against the challenge exposure were observed among the groups. Therefore, the present results suggest that these selected antibiotics would not interfere with the immune effect of the vaccine if given at the usual concentrations used for feed additives. 相似文献
8.
Immunization of pigs against Streptococcus suis serotype 2 infection using a live avirulent strain. 总被引：6，自引：3，他引：3 
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下载免费PDF全文 Streptococcus suis capsular type 2 is still an important cause of economic losses in the swine industry. At the present time, vaccination of pigs against this infection is generally carried out with autogenous bacterins and results are equivocal. In this study, the protective effect of a live avirulent S. suis type 2 strain (#1330) which had induced a good protection in mice, was evaluated in swine. The experiment was performed in triplicate using 4 week-old piglets. A total of 15 piglets were vaccinated 3 times, 15 others were vaccinated 2 times, and 15 piglets were injected 3 times with sterile Todd-Hewitt broth. Using an indirect ELISA, an increase in the IgG response to S. suis antigens was noted in 27 of the 30 vaccinated piglets. On day 21 post-vaccination, all animals were challenged intravenously with a virulent S. suis type 2 strain (#999). In the 2 vaccinated groups, 26 animals were fully protected. Only 1 out of the 15 piglets vaccinated 3 times developed mild clinical signs. In the group vaccinated twice, 3 piglets showed clinical signs and 1 of them died after the challenge. In the control group, 7 animals died out of the 11 with clinical signs of infection. In conclusion, a protective immunity was observed in swine when using strain 1330. However, more studies are needed to assess the use of a live S. suis strain in a vaccine for pigs. 相似文献
9.
In each of three trials, 240 crossbred barrows weaned at 17 d of age (5.1 kg BW) were assigned to one of three experimental treatments based on light and heavy weight outcome groups. Experimental treatments were 1) wean-to-finish at 0.69 m2/pig and 15 pigs/pen; 2) wean-to-finish double-stocked at 0.35 m2/pig, 30 pigs per pen for 8 wk and then randomly split into two pens (either stayed in same pen or moved to new pen) for growth to slaughter at 0.69 m2/pig; and 3) nursery facility for 8 wk at 0.35 m2/pig and 15 pigs/pen followed by move to the same grow-finish facility housing wean-to-finish and double-stocked pigs and maintaining pen integrity. Beginning at 38 kg BW, diets were supplemented with either bacitracin methylenedisalicylate at 33 mg/kg to slaughter or tylosin at 44 mg/kg to 59 kg BW and 22 mg/kg thereafter. There were no trial x treatment interactions, even though there was considerable variation in health status among trials. At the end of the 56-d nursery period, wean-to-finish pigs weighed more than nursery (28.7 vs 27.7 kg; P = 0.071) and double-stocked pigs (28.7 vs 26.9 kg; P = 0.002), due to greater ADG (wean-to-finish vs nursery; P = 0.062; wean-to-finish vs double-stocked; P = 0.002) and greater ADFI (wean-to-finish vs nursery; P = 0.024; wean-to-finish vs double-stocked, P = 0.002). There was no effect of treatments (P > 0.1) on ADG, feed conversion, carcass lean percentage, or lean gain during the growing-finishing period. There was also no effect of treatment (P > 0.1) on ADG or ADFI from weaning to slaughter. There was no difference (P > 0.1) between bacitracin methylenedisalicylate and tylosin for ADG, feed conversion, carcass lean percentage, or daily lean gain. These data suggest that housing 5-kg weaned pigs in fully slatted growing-finishing facilities from weaning to slaughter was not detrimental to overall performance. In this experiment, dietary additions of bacitracin methylenedisalicylate or tylosin from 38 kg BW to slaughter weight resulted in similar growth performance. 相似文献
10.
本试验旨在研究不同饲粮消化能水平在高温高湿饲养环境下对生长肥育猪生长性能、血清生化指标和肉品质的影响,以确定生长肥育猪适宜的消化能水平。选取平均初始体重为(40.0±2.0)kg的健康“杜×长×大”生长猪50头,随机分为5个组,每个组10个重复(7头公猪,3头母猪),每个重复1头猪。5个组试验猪分别饲喂消化能水平为13.68、13.88、14.09、14.30和14.51 MJ/kg的饲粮,试验期为90 d。结果表明:1)在高温高湿环境下,随着饲粮消化能水平的提高,试验猪生长期、育肥期及试验全期的平均日采食量呈下降趋势,而平均日增重(ADG)呈先升高后降低、料重比呈先降低后升高的趋势。猪生长期和全期的ADG与饲粮消化能水平的曲线方程分别为Y1=-878.02X^2+24708.94X-173289.53(R^2=0.69,P<0.01)和Y2=-436.56X^2+12276.96X-85600.33(R^2=0.54,P<0.05),当ADG达到最大时,对应的饲粮消化能水平分别为14.07和14.06 MJ/kg。2)饲粮消化能水平对生长肥育猪血清总蛋白、高密度脂蛋白胆固醇和免疫球蛋白G含量存在显著影响(P<0.05),并且以14.09 MJ/kg消化能组最高(P<0.05)。3)饲粮消化能水平对生长肥育猪血清脂蛋白脂肪酶、脂肪酶(LPS)活性分别有极显著(P<0.01)和显著性(P<0.05)影响,而对血清苹果酸脱氢酶活性以及脂联素和生长激素含量没有显著影响(P>0.05);猪血清LPS活性与饲粮消化能水平的曲线方程为Y3=133.00X^2-3761.26X+26664.78(R^2=0.83,P<0.05),当血清LPS活性最低时,对应饲粮消化能水平为14.14 MJ/kg。4)随着饲粮消化能水平的提高,生长育肥猪的皮脂率显著提高(P<0.05),肌肉滴水损失和剪切力显著降低(P<0.05),并以14.09 MJ/kg消化能组的肉品质最优,其滴水损失和剪切力显著低于13.68 MJ/kg消化能组(P<0.05);猪肉滴水损失和剪切力与饲粮消化能水平的曲线方程分别为Y4=0.70X^2-19.92X+143.25(R^2=0.96,P<0.05)和Y5=2.88X^2-82.20X+590.36(R^2=0.99,P<0.05),当肌肉滴水损失、剪切力达到最低时,对应的饲粮消化能水平分别为14.23和14.27 MJ/kg。 相似文献
11.
Mavromatis I Kritas SK Alexopoulos C Tsinas A Kyriakis SC 《Zentralblatt für Veterin?rmedizin. Reihe B. Journal of veterinary medicine. Series B》1999,46(9):603-612
A live vaccine based on a European isolate of porcine reproductive and respiratory syndrome virus (Porcilis PRRS) was tested in this study in order to determine the protection of fattening pigs against the respiratory form of the syndrome under field conditions. Ten thousand pigs in an infected farm were vaccinated against PRRS virus at the age of 6 weeks and were compared with non-vaccinated pigs with respect to their health status, mortality, performance parameters (average daily gain, average daily feed intake, feed conversion ratio) and the presence of certain pathogens in their lungs. The results showed that treated pigs became ill less frequently and demonstrated reduced mortality compared with untreated ones. As compared with non-vaccinated animals, PRRS-vaccinated pigs also performed in a better way with respect to the feed conversion ratio (P < 0.05) and average daily gain (P < 0.05), while feed intake was similar for both groups (P > 0.05). Bacteriological examinations of the lungs revealed increased incidence of respiratory bacterial infection in untreated pigs compared with treated ones. A tendency for a faster antibody response was also detected in the vaccinees. The results of the present study show that immunization with a live vaccine does protect fattening pigs against the respiratory manifestations of PRRS. 相似文献
12.
本研究旨在探讨饲用玉米对生长育肥猪生产性能的影响。选取体重(40±1) kg相近的大白×长白×杜洛克商品猪21头,随机分为3组,每组7头,分别饲喂以普通玉米（N组）和饲用玉米吉单198（T1组）、吉单327（T2组）为饲料原料的日粮,进行了78 d的饲养试验。结果表明,T1组、T2组育肥猪的日增重分别较N组提高了10.37%、2.22%,各组试验猪的饲料转化效率基本一致。平均每头猪的纯收入：T1组和T2组分别比对照组每头多85.1和36.1元。因此,本试验结果表明,饲用玉米能够提高生长育肥猪的生产性能,从而增加养殖效益。 相似文献
13.
Okada M Sakano T Senna K Maruyama T Murofushi J Okonogi H Sato S 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》1999,61(10):1131-1135
An inactivated vaccine prepared from broth culture supernatant of Mycoplasma hyopneumoniae with an aluminum adjuvant was evaluated in three herds (herd A: specific pathogen-free herd, herd B: high health status herd with no clinical signs of respiratory infection, herd C: low health status herd with serious epidemiological and economical problems). A total of 212 pigs from the three herds were divided into two groups. One group was injected twice with the vaccine at 4-week intervals and the other was a control group. No adverse reactions were noted following the vaccinations either systematically or locally in any of the vaccinated pigs from any of the herds. In herd A, the vaccination provided antibody response within 4 weeks after the second vaccination and antibody responses continued for more than 12 weeks. In herds B and C, the number of pigs with lung lesions, mean percentage of lung lesions, and the numbers of M. hyopneumoniae recovered from pigs at slaughter in the vaccinated group were significantly (P < 0.05) reduced compared to the control group. Furthermore, vaccination resulted in improved average daily weight gain (ADG), improved feed conversion ratio (FCR), and improved days to market weight in herd C, whereas no difference in growth performance was shown in herd B. It is suggested that the inactivated vaccine prepared from broth culture supernatant of M. hyopneumoniae is effective in reducing clinical signs and lung lesions. Also, vaccination resulted in improved growth performance in herds where clinical signs and economic losses were significant. 相似文献
14.
Six hundred forty growing-finishing pigs (initial BW = 23.2 +/- 4.8 kg) were used in a 12-wk study (final BW = 95.5 +/- 10.2 kg) to quantify the effects of group size (10, 20, 40, and 80 pigs/pen) on performance, tail biting, and use of widely distributed feed resources. One single-space wet/dry feeder was provided for every 10 pigs, and floor allowance was 0.76 m2/pig in all treatment groups. Weight gain and feed intake were measured every 2 wk. At weighing, a tail-biting injury score was given to each pig. Blood samples were collected and analyzed for neutrophil:lymphocyte ratio before regrouping at the beginning of the experiment, 24 to 48 h after regrouping, and on the last day of each trial. The use of feeders by individual pigs was assessed by behavioral observations. Average daily gain for the entire 12-wk trial did not differ among group sizes (861, 873, 854, and 845 g/d for groups of 10, 20, 40, and 80, respectively; P > 0.10). During the first 2 wk, ADG was lower for pigs in groups of 40 (554 g/d) than pigs in groups of 10 (632 g/d; P < 0.05), but not pigs in groups of 20 or 80 (602 and 605 g/d, respectively). Average daily feed intake, feed efficiency, and variability in final BW within a pen also did not differ among group sizes. Tail-biting injury scores increased throughout the study, but did not differ among group sizes. Similar proportions of pigs were removed from the trial for health reasons, primarily due to tail biting, in all treatments. Individual pigs in each group size ate from most, if not all, of the feeders in the pen. There was no evidence of spatial subgrouping within the larger groups. The results suggest that housing growing-finishing pigs in groups of up to 80 pigs is not detrimental to productivity and health if space allowance is adequate and feed resources are evenly distributed. 相似文献
15.
为了研究低聚木糖(XOS)对生长肥育猪生长性能、胴体性状和肉品质的影响,试验选取平均体重为30 kg左右的三元杂交猪80头,随机分为8组,每组10头,公、母各占1/2,单栏饲养。试验设对照组、抗生素组,3065 kg阶段100、250和500 g/t XOS组,以及30100 kg阶段100、250和500 g/t XOS组。分别于试验开始和结束时记录每头猪的空腹体重及采食量,计算平均日采食量(ADFI)、平均日增重(ADG)和料重比(F/G);于试猪平均体重达100 kg时屠宰采样,测定胴体性状、肉品质和肌肉化学成分。结果表明:与对照组或抗生素组相比,饲粮添加不同剂量的XOS对生长肥育猪的ADFI、ADG、F/G、胴体性状和肉品质均无显著影响(P0.05);3065 kg阶段添加250 g/t XOS可显著增加脾脏指数以及背最长肌粗蛋白质含量(P0.05);30100 kg阶段添加500 g/t XOS可显著增加脾脏指数及背最长肌粗蛋白质含量(P0.05)。综上所述,饲粮添加不同剂量的XOS虽对生长肥育猪的ADFI、ADG、F/G、胴体性状和肉品质等指标影响不显著,但可通过增加肌肉粗蛋白质含量而改善猪肉营养价值;以30100 kg阶段添加500 g/t XOS效果较佳。 相似文献
16.
放牧对松辽黑猪生长肥育及胴体肉质的影响 总被引：2，自引：0，他引：2
选择松辽黑生长育成猪200头,分成舍饲组和林地放牧组,进行饲养育肥性能测定。舍饲组按常规全期饲喂全价配合精饲料;放牧组则先在舍内育成至体重达40kg后,白天林地放牧,早晚各补饲一次精饲料,直至达到育肥体重。饲养试验结束,各饲养组选取4头(2公2母)体重100kg左右的试验猪,进行屠宰做胴体肉质测定。结果表明:日增重舍饲组为736.5g,放牧组为467.5g,差异极显著(<0.01),而放牧组则每增重1kg比舍饲组少耗精饲料730g,差异显著(<0.05)。屠宰率放牧组为70.71%,比舍饲组的69.21%高,差异显著(<0.05),肌内脂肪含量放牧组为4.92%,舍饲组为3.60%,差异显著(<0.05),其它胴体肉质指标如眼肌面积、背膘厚、瘦肉率及肉色、pH、失水率、嫩度等,两种饲养方式,差异均不明显,但放牧饲养组要比舍饲组有改善和提高的趋势。 相似文献
17.
Duy Tien Do Khanh Doan Vinh Tran Anh Tuyet Quach David Lee Frank CJ Chang Carol PY Wu Toan Nguyen Tat Chanhee Chae 《Canadian journal of veterinary research》2021,85(2):93
The aim of this study was to evaluate the protective efficacy of the CIRCOQ porcine circovirus type 2 (PCV2) subunit vaccine in piglets with high maternally derived antibodies (MDAs) against disease caused by natural infection with PCV2d. A total of 130 weaned, 21-day-old healthy pigs was allocated into 3 trial groups. The signs of respiratory disorder were higher in unvaccinated pigs than in vaccinated pigs at 13 to 17 weeks old (P < 0.05), 18 to 22 weeks old (P < 0.001), and 23 to 27 weeks old (P < 0.01). The unvaccinated pigs had an early rate of dermatitis at 8 to 12 weeks old (10.0%), 13 to 17 weeks old (30.0%), 18 to 22 weeks old (46.7%), and 23 to 27 weeks old (33.3%), while there were no cases of dermatitis in vaccinated pigs. There was a significant difference (P < 0.05) in the mortality of pigs in the unvaccinated group and the 2-dosed vaccinated group. PCV2 viremia was detected in the blood and peaked at 105 days old in both unvaccinated pigs (Ct-adj = 8.40) and pigs vaccinated with 1 dose (Ct-adj = 6.37), while no detectable PCV2 virus was found in the blood of pigs vaccinated with 2 doses. At 77 and 105 days old, the PCV2 viremia load (Ct-adj) of unvaccinated pigs and those vaccinated with 1 dose was significantly higher (P < 0.05) than that of the 2-dosed vaccinated pigs. The body weight (BW), average weight gain (AWG), and average daily gain (ADG) in both groups of vaccinated pigs were significantly higher (P < 0.05) than those of unvaccinated pigs. The study vaccine was significantly efficacious in protecting vaccinated pigs against clinical symptoms, blood viral load, and mortality, as well as improving productivity, compared with unvaccinated pigs. 相似文献
18.
S J Cysewski R L Wood A C Pier A L Baetz 《American journal of veterinary research》1978,39(3):445-448
The effect of aflatoxin consumption on the development of acquired immunity to swine erysipelas was studied. Twenty-four pigs were divided into 4 groups (6 pigs/group). Two groups were fed a normal diet and 2 groups were fed the same diet but containing aflatoxin. One group from each diet treatment was given a single injection of an erysipelas bacterin, and 21 days later all pigs were given a challenge inoculum of virulent Erysipelothrix rhusiopathiae organisms. On the basis of the response to the challenge inoculation, pigs were classified as immune, partially immune (PI), or susceptible. Three of the vaccinated pigs fed the normal diet were immune, 2 were PI, and 1 was susceptible, whereas none of the vaccinated pigs given the aflatoxin diet were immune, only 1 was PI, and the remainder were susceptible. Two of the nonvaccinated pigs fed the normal diet were PI and 4 were susceptible; all of the nonvaccinated pigs fed the aflatoxin diet were susceptible. It was concluded that aflatoxin consumption interfered with the development of acquired immunity and apparently increased the severity of the E rhusiopathiae infection in unvaccinated pigs. 相似文献
19.
Ten pregnant gilts were divided into two groups of five and one group was vaccinated at 80 and 95 days of pregnancy with a commercial bacterin containing Haemophilus parasuis serovars 2, 3 and 5. Half the piglets born to each group of gilts were vaccinated at seven and 21 days of age with the same bacterin, and one week after they were weaned at five weeks, all the piglets were inoculated intratracheally with 10(6) colony-forming units of Hparasuis serovar 5. At slaughter, a significantly smaller percentage of the lungs of the pigs born to the vaccinated gilts was affected by pneumonic lesions, and significantly fewer of them had arthritic joint changes. The average daily liveweight gain of the pigs born to the vaccinated gilts was significantly greater than that of those born to the unvaccinated gilts, but the vaccination of the piglets had no effect. There was no significant difference between the feed conversion ratios of the four groups of piglets, and none between the average times they took to reach slaughter weight. The pigs born to the vaccinated gilts had higher ELISA titres to Hparasuis than those born to the unvaccinated gilts. 相似文献
20.
Karg G Bilkei G 《Journal of veterinary medicine. B, Infectious diseases and veterinary public health》2002,49(10):464-468
The objective of this field trial was to determine if vaccination against Haemophilus parasuis serovar 5 (HPS 5) and pathogenic serotypes of Escherichia coli would improve nursery pig performance in an outdoor unit in different seasons. The unit was concurrently infected with HPS 5 and with different serotypes of E. coli. All piglets were born to HPS 5 vaccinated sows. The trial was carried out in four (two summer and two winter) groups. Group 1 (E. coli and HPS vaccinated, summer season) (n = 362): Piglets were vaccinated pre-weaning with inactivated E. coli-VT2e-toxin and post-weaning against HPS 5. Group 2 (non-vaccinated, summer season) (n = 349): Piglets were not vaccinated. Group 3 (E. coli and HPS vaccinated, winter season) (n = 358): The animals were analogously treated as Group 1. Group 4 (non-vaccinated, winter season) (n = 353): Piglets were not vaccinated. The following parameters were evaluated: A: average daily nursery weight gain (ADG), B: nursery mortality, C: feed efficiency (FE). No significant weight differences were detected within the vaccinated and non-vaccinated summer or winter raised groups of weaners. Summer raised weaners were significantly (P<0.05) heavier from day 35 on than winter raised animals. ADG and FE of summer raised pigs were significantly better (weeks 1-3 P<0.05; fourth week post-weaning P<0.01) during the nursery period than that of the winter raised groups. Winter raised vaccinated weaners showed during the last week of nursing significantly (P<0.05) better daily gain and feed efficiency compared with the non-vaccinated winter raised animals. Non-significant ADG and FE differences were detectable between the summer raised vaccinated or non-vaccinated groups of pig. Winter raised non-vaccinated animals suffered significantly (P<0.05) higher nursery mortality (10.63%) compared to the winter raised vaccinated animals. Implication: In cases of concurrent infections with HPS 5 and with different serotypes of E. coli, especially during winter season, vaccination against both diseases is suggested. 相似文献