共查询到19条相似文献，搜索用时 500 毫秒
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为了对比腹腔镜和开腹肾脏切除手术对犬机体氧化应激的影响,为腹腔镜手术在兽医领域的发展提供理论依据,试验在犬腹腔镜和开腹组肾脏切除术前及术后即刻、4小时、1天、2天采取静脉血,检测丙二醛(MDA)、超氧化物歧化酶(SOD)和谷胱甘肽过氧化物酶(GSH-Px)。结果表明:腹腔镜和开腹肾脏切除术都使MDA含量升高,SOD和GSH-Px水平降低。但是腹腔镜组影响较为迅速,术后4小时与术前相比差异极显著(P<0.01),术后1天就恢复到术前水平;开腹组术后1天才与术前相比差异显著(P<0.05),术后2天也未能恢复到术前水平。说明腹腔镜和开腹肾脏切除术都能造成犬机体氧化应激损伤,但与开腹肾脏切除术相比,腹腔镜手术对动物机体氧化应激损伤轻。 相似文献
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肝部分切除术主要用于治疗良性肿瘤、部分恶性肿瘤、肝脓肿、肝棘球蚴或肝外伤等.由于肝脏解剖及生理特点的特殊性,传统开腹肝部分切除术对机体影响较大.与传统开腹手术相比,腹腔镜手术具有手术视野清晰、出血量少、恢复快、疼痛反应轻等优点.Reich等[1]于1991年首次成功施行了腹腔镜肝脏浅表良性肿瘤局部切除术.应用微创技术实施肝部分切除是肝脏外科发展的必然趋势.在兽医领域,犬肝部分切除术主要集中在开腹手术,犬腹腔镜肝部分切除术的试验研究在国内罕见报道.我们实施了犬腹腔镜肝部分切除术,报告如下. 相似文献
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《中国畜牧杂志》2015,(23)
本研究旨在探讨2种安装多位点血管瘘手术方法对山羊机体免疫应激的影响。选取8只体重相近、年龄约1岁的健康麻城黑山羊公羊,按体重相近的原则分成2组,分别采用腹腔镜法与传统开腹法手术安装山羊肠系膜静脉、门静脉及肝静脉血管瘘管。测定术前、术后第1、3、5天试验羊血清免疫应激指标。结果表明:术后第1天,腹腔镜组白细胞总数显著低于开腹组(P0.05),C反应蛋白(CRP)水平极显著低于开腹组(P0.01),Ig G水平显著高于开腹组(P0.05);术后第3天,腹腔镜组IL-6、CRP水平显著低于开腹组(P0.05);术后腹腔镜组和开腹的TNF-α、Ig A和Ig M水平差异不显著(P0.05)。本试验结果表明,腹腔镜手术对山羊机体应激更小,机体免疫功能恢复更快。 相似文献
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犬肾上腺切除手术在兽医临床中不是常见的手术,其适应症是各种肾上腺肿瘤[1],兽医临床实践中现主要采用开腹手术方法完成.腹腔镜手术具有创伤小、疼痛轻和术后恢复快的特点,在人类医学广泛应用,1992年Gagner M等[2]首次报道,3例人腹腔镜肾上腺切除术,从此以后腹腔镜肾上腺切除术逐渐推广应用,现在认为是肾上腺手术的首选治疗方法及金标准[3-5].在小动物临床实践中腹腔镜技术也得到了一定的发展,并且有文章报道,腹腔镜犬肾上腺切除手术[6],但国内还未发现有应用腹腔镜技术完成犬肾上腺切除的手术.因此,本试验的目的是利用腹腔镜手术技术来完成犬肾上腺的切除,并且改进其技术方法,为以后国内兽医临床实践中发展腹腔镜犬肾上腺切除术提供一些经验. 相似文献
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《黑龙江畜牧兽医》2016,(11)
为了探讨犬腹腔镜肾脏切除术对犬生理功能的影响,促进犬腹腔镜肾脏切除术在兽医临床实践中的应用。试验在手术过程中应用呼吸监护仪和重症监护仪监测犬循环和呼吸系统生理指标;术后抽取静脉血,检测天门冬氨酸氨基转移酶(AST)、丙氨酸氨基转移酶(ALT)、碱性磷酸酶(ALP)、尿素氮(BUN)和肌酐(Cr)水平;综合评价犬腹腔镜肾脏切除术对犬生理功能的影响。结果表明:试验中收缩压(SBP)、舒张压(SDP)、平均动脉压(MAP)、心率(HR)、呼吸频率(RR)、呼吸末二氧化碳(Pet CO2)逐渐降低,但在手术结束后基本恢复正常水平,与术前相比差异不显著(P0.05);犬腹腔镜肾脏切除术对动物肝脏功能和肾脏功能也有一定影响,但很快就恢复到正常水平,术后第7天各检测指标与术前相比差异不显著(P0.05)。说明犬腹腔镜肾脏切除术对犬机体生理功能有一定影响,但都在犬可耐受范围内,可以安全地在兽医临床实践中应用。 相似文献
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《畜牧与兽医》2017,(3):84-88
本试验旨在比较腹腔镜下肾部分切除与肾切除对小型猪肝肾功能的影响,评估手术的安全性与可行性,为两种手术方法的应用提供科学依据。试验以10头广西巴马小型猪为研究对象,随机分为腹腔镜肾部分切除术组(LPN组)与腹腔镜肾切除术组(LRN组),分别于术前、术后即刻、术后1d、2d、3d、5d、7d、14d采取前腔静脉血,检测肝功能指标丙氨酸转氨酶(ALT)、天门冬氨酸转氨酶(AST),肾功能指标β2微球蛋白(β2-MG)、肾损伤分子-1(KIM-1)、胱抑素C(CYS-C),比较其差异性。结果显示,两组手术均成功完成,肝、肾功能指标均呈先升高后降低趋势,与试验前相比差异极显著(P0.01)。LPN组术后肝功能指标高于LRN组,差异极显著(P0.01);LPN组术后肾功能指标略高于LRN组,无显著性差异(P0.05),LPN组肾功能指标恢复至术前水平更快速。结果表明,LPN较LRN在短期内会造成更严重的肝肾损伤,但更有利于肾功能恢复,临床上应依据不同情况进行选择。 相似文献
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《中国兽医学报》2014,(12):2005-2008
对14头健康小型猪分别进行开腹(open cystostomy,OC)、腹腔镜膀胱造口手术(laparoscopic cystostomy,LC),通过检测小型猪术后不同时间点血清皮质醇(cortisol,COR)、白介素-6(Interleukin-6,IL-6)和C反应蛋白(C-reactive protein,CRP)的变化,比较OC手术与LC手术对机体应激反应的影响。结果表明,LC、OC2组分别在不同时间点所检测到的的COR、IL-6和CRP与试验前相比,都有极显著性差异(P<0.01)。在术后即刻和4h后OC组对应激指标的影响要明显高于LC组,并且术后3dLC组都恢复到试验前水平,而OC组术后5d才恢复。说明LC和OC都可导致血清中COR、IL-6、CRP水平的升高,但OC较LC对COR、IL-6和CRP的影响更为显著,即腹腔镜膀胱造口手术比开腹膀胱造口手术对机体应激反应的影响更小。 相似文献
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Brigid R Burns Erik H Hofmeister Benjamin M Brainard 《Veterinary anaesthesia and analgesia》2014,41(2):186-190
ObjectiveTo determine if dogs that undergo laparotomy for cholecystectomy suffer from a greater number or magnitude of perianesthetic complications, including hypotension, hypothermia, longer recovery time, and lower survival rate, than dogs that undergo laparotomy for hepatic surgery without cholecystectomy.Study designRetrospective cohort study.AnimalsOne hundred and three dogs, anesthetised between January 2007 and October 2011.MethodsThe variables collected from the medical record included age, weight, gender, surgical procedure, pre-operative bloodwork, American Society of Anesthesiologists (ASA) status, emergency status, total bilirubin concentration, anesthetic agents administered, body temperature nadir, final body temperature, hypotension, duration of hypotension, blood pressure nadir, intraoperative drugs, anesthesia duration, surgery duration, time to extubation, final diagnosis, days spent in the intensive care unit (ICU), total bill, survival to discharge, and survival to follow-up.ResultsNo significant difference in body temperature nadir, final temperature, presence of hypotension, duration of hypotension, blood pressure nadir, the use of inotropes, or final outcome was found between dogs undergoing cholecystectomy and dogs undergoing exploratory laparotomy for other hepatic disease. Dogs that had cholecystectomy had longer anesthesia durations and longer surgery durations than dogs that did not have cholecystectomy. No significant differences existed for temperature nadir (34.8 versus 35.3 °C; non-cholecystectomy versus cholecystectomy), final temperature (35.6 versus 35.9 °C), time to extubation (30 versus 49 minutes), duration of hypotension (27 versus 21 minutes), or MAP nadir (56 versus 55 mmHg). Hypotension occurred in 66% and 74% and inotropes were used in 64% and 53%, for non-cholecystectomy and cholecystectomy patients, respectively.Conclusions and clinical relevanceDogs that underwent cholecystectomies did not suffer a greater number of anesthesia complications than did dogs undergoing hepatic surgery without cholecystectomies. 相似文献
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Guillaumin J Chanoit G Decosne-Junot C Goy-Thollot I 《The Journal of small animal practice》2006,47(12):733-736
A 10-year-old, entire female Pyrenean shepherd dog was presented for acute onset of gastroenteritis. An abdominal ultrasound examination showed the presence of a suspected gall bladder mucocele. After surgery for cholecystectomy, the dog showed signs of an acute onset of respiratory distress due to bilothorax. The bilothorax responded well to medical treatment that comprised of thoracocentesis and oral steroids. 相似文献
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Prowse EA 《The Canadian veterinary journal. La revue veterinaire canadienne》1984,25(5):201-203
An eight year old mixed terrier bitch was presented for examination because of apparent recurrent episodes of acute abdominal pain. Though of short duration, these episodes had been occurring for about two months. Radiographs were taken and two cholecystoliths were observed. Cholecystectomy resulted in resolution of the abdominal pain. 相似文献
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Monty Galley Jennifer Lang Mark Mitchell Jon Fletcher 《The Canadian veterinary journal. La revue veterinaire canadienne》2022,63(1):63
Gallbladder mucocele (GBM) is a commonly diagnosed disease process in dogs that is associated with high morbidity and mortality if not recognized and appropriately managed. Although the exact mechanism of this disease process is not completely understood, previous studies in smaller populations of dogs have identified multiple factors that predispose to the development of GBM and affect survival. The purpose of this cross-sectional, retrospective study was to evaluate the effects of age, breed category, sex, preoperative antibiotic administration, gallbladder rupture, and a positive biliary culture in dogs that had a cholecystectomy performed for the treatment of GBM. The age (median: 11 years) and percentage of dogs that died within 14 days of cholecystectomy (16.7%) are similar to what have been reported in other studies. Gallbladder rupture and a positive biliary culture occurred in 20.4% and 12.5% of dogs, respectively. Dogs with a gallbladder rupture and positive biliary culture were 2.74 and 3.10 times more likely to die within 14 days of cholecystectomy, respectively. This contradicts a recent study that failed to find a significant association between survival and biliary culture result. Interestingly, younger age was associated with an increased occurrence of gallbladder rupture in that population. Because of the potential effect of gallbladder rupture and a biliary tract infection, abdominal imaging, biliary culture, and empirical preoperative antimicrobial therapy are recommended in dogs undergoing cholecystectomy for the treatment of GBM. 相似文献
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Pizzi R Cracknell J David S Laughlin D Broadis N Rouffignac M Duong DV Girling S Hunt M 《The Veterinary record》2011,169(18):469
Nine adult Asiatic black bears (Ursus thibetanus) previously rescued from illegal bile farming in Vietnam were examined via abdominal ultrasound and exploratory laparoscopy for liver and gall bladder pathology. Three bears demonstrated notable gall bladder pathology, and minimally invasive cholecystectomies were performed using an open laparoscopic access approach, standard 10 to 12 mmHg carbon dioxide pneumoperitoneum and a four-port technique. A single bear required insertion of an additional 5 mm port and use of a flexible liver retractor due to the presence of extensive adhesions between the gall bladder and quadrate and left and right medial liver lobes. The cystic duct was dissected free and this and the cystic artery were ligated by means of extracorporeal tied Meltzer knot sutures. The gall bladder was dissected free of the liver by blunt and sharp dissection, aided by 3.8 MHz monopolar radiosurgery. Bears that have had open abdominal cholecystectomies are reported as taking four to six weeks before a return to normal activity postoperatively. In contrast, these bears demonstrated rapid unremarkable healing, and were allowed unrestricted access to outside enclosures to climb trees, swim and interact normally with other bears within seven days of surgery. 相似文献