共查询到20条相似文献，搜索用时 203 毫秒
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H M Burbidge N Kannegieter L R Dickson B E Goulden L Badcoe 《Equine veterinary journal》1989,21(5):347-350
Iohexol, a water soluble non-ionic contrast agent, was evaluated for myelography in the horse. Both 300 and 350 mg iodine/ml iohexol gave diagnostic cervical myelograms. Pathological changes were limited to extradural oedema and an increase in the number of white blood cells and specific gravity in the cerebrospinal fluid two days after myelography. This increase in white blood cells in the cerebrospinal fluid was, however, much less than that recorded by other authors using metrizamide and iopamidol contrast media. These findings indicate that iohexol is a less irritant myelographic contrast agent than those previously evaluated in the horse. 相似文献
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B Funkquist 《Acta veterinaria Scandinavica》1975,16(2):269-287
Metrizamide is a new water-soluble contrast medium possessing unique properties, one of which is that even in an isotonic solution it has a radiographic density sufficient for a diagnostic myelogram. Whereas in the past myelography with water-soluble preparations invariably entailed lumbar injections, which are technically difficult in dogs, the fact that isotonic metrizamide causes so little tissue irritation has made it possible to inject the contrast solution into the cisterna magna. The author has compared metrizamide myelograms obtained with both cisternal and lumbar injections. Myelography with a cisternal injection is preferable for demonstrating cervical cord compressions and also in cases in which it is desirable to obtain myelographic information on both the cervical and the thoraco-lumbar areas. If, on the other hand, it is necessary to determine exactly the extent of a thoraco-lumbar compression before decompressive laminectomy, the contrast should be injected in the lumbar region in such an amount and at a pressure high enough to ensure that the contrast is forced past the site of the compression. The safety of metrizamide will probably enable a better prognosis following surgery than was previously possible. 相似文献
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Tne use of the contrast agent meglumine iocannate+ 60% for myelography in 31 dogs (25 clinical cases and 6 experimental dogs)is described. In the experimental dogs, there was a transient rise in both blood pressure and cerebrospinal fluid pressure after injection of Dimer X into the lumbar subarachnoid space, but dilution of the medium, or the addition of lignocaine, were not considered necessary. In 24 of the 25 clinical cases, the lumbar transpinal technique for myelography was used. A 5ml, or 3 ml (for dogs under15 kg), dose of Dimer X was administered and the contrast column moved to the expected site of the lesion by inclining the dog. Ten of the 25 clinical cases showed adverse side-effects after myelography and diazepam (Valium 10 — Roche) was administered to control them. In 7 of the 10 dogs that showed side-effects, the contrast medium had reached the upper cervical, or cranial, subarachnoid space. Dimer X provided excellent radiographic contrast and diagnostic myelograms in all clinical cases. It was concluded that it was a suitable contrast agent for thoracolumbar myelography. In the absence of a suitable alternative for cervical myelography, it can be used, but side-effects must be expected and control measures taken. 相似文献
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Anthony D. Pardo MS DVM. Joe P. Morgan DVM Vet med dr 《Veterinary radiology & ultrasound》1988,29(2):89-95
Metrizamide myelographic examinations were performed on five normal cats using sequential cisternal and lumbar injections at weekly intervals to determine the dose of contrast medium required, adverse effects, and quality of the myelographic study. The normal myelographic appearance in the cat is described. All spinal cords were examined histopathologically after the termination of the study, and variable mild lesions were found. Doses of 0.2 ml/kg, 0.35 ml/kg, and 0.4 ml/kg metrizantide, respectively, for lumbar, thoracolumbar, and complete spinal studies are recommended when performing lumbar injection. Recommended doses using cisternal injection for cervical, cervicothoracic, and complete spinal studies are 0.2, 0.45, and 0.5 ml/kg, respectively. Subjectively, lumbar injection produced higher-quality thoracolumbar myelograms and cisternal injection produced higher-quality cervical studies. Clinical complications during the study included one seizure following cisternal myelography and mild neurologic deficits in all cats, which resolved within 36–48 hours. 相似文献
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During this investigation, the use of iohexol was compared with iotrolan for canine cisternal myelography. Iohexol and iotrolan myelography was done in 6 dogs by cisternal puncture with a 6-week interval between both procedures; each dog served as its own control. Cerebrospinal fluid (CSF) was collected for baseline analysis from each dog immediately before the contrast agent was injected. Cerebrospinal fluid samples were obtained at 1, 3, 7, and 14 days after injection of each contrast medium for cytologic and chemical analysis. Total CSF leucocyte count and glucose concentration did not change significantly in comparison with baseline data in any of the samples. After the injection of iohexol, protein concentration increased significantly in the 24-hour sample, and lactate dehydrogenase activity increased significantly in the 3-day sample. Significant difference was not found between the different samples collected at 1, 3, 7, and 14 days, compared with both contrast media. None of the dogs had seizure activity during a 5-hour postmyelographic observation period. Pathologic changes were not found by gross or microscopic examination of the spinal cord. Although a degradation in time of radiographic quality of all myelograms took place, the average radiographic score decreased more rapidly with iohexol. The average score at 90 minutes with iotrolan was comparable with the score at 45 minutes with iohexol, and the average score at 150 minutes with iotrolan was better than the score at 90 minutes with iohexol. At 5 and 10 minutes after cisternal injection, no significant difference was observable between the myelograms, but from 45 minutes onward, myelograms with iotrolan were superior. 相似文献
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The results of a prospective study to compare the plain radiographic and lumbar myelographic findings with the surgical findings in 70 cases of suspected thoracolumbar disc protrusion in the dog are reported. The aim was to assess the relative accuracy of disc lesion localisation using plain and contrast radiography. From the plain radiographs, the affected disc space was correctly identified in 40 cases (57.1 per cent), and incor- rectly identified in seven. More than one site was identified in 11; in eight of these dogs, the affect- ed disc space was strongly suspected. It was not possible to identify an affected disc in 12 cases. The site of disc protrusion was accurately identified by myelography in 60 dogs (85.7 per cent). In four dogs, myelography was helpful in identifying an adjacent disc and, in a further two, cord swelling was found at surgery. In one dog, neither disc material nor cord swelling was identified. Three myelograms were non-diagnostic. 相似文献
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Iseri T Yamada K Ueno H 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2004,66(1):71-72
In search of a safer myelographic technique, we performed myelography via the lumbosacral intervertebral space. Eight dogs, in which the backflow of cerebrospinal fluid was observed, received contrast media via the lumbosacral intervertebral space. The subarachnoid contrast columns were successfully observed in 6 dogs. During and after examination, no physiological changes or neurological signs were observed. We recommend that the lumbosacral intervertebral space be selected first before implementing the conventional lumbar myelography. 相似文献
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Medical records of 66 dogs that had undergone myelography, using iohexol (240 mg of iodine/ml, 0.3 to 0.5 ml/kg of body weight) during a 2-year period, were reviewed. In 3 dogs, myelography was performed twice during different anesthetic procedures. Neurologic abnormalities were more pronounced the day after myelography in dogs with caudal cervical spondylomyelopathy (P less than 0.01), meningitis (P less than 0.01), or extradural tumors (P less than 0.05). Neither anesthetic regimen nor duration of anesthesia significantly affected the frequency of complications. Seizures occurred after myelography in 6 dogs, and 1 dog had seizures after each of 2 myelographic procedures. The frequency of seizures was significantly greater in male Doberman Pinschers afflicted with caudal cervical spondylomyelopathy. Male dogs (P less than 0.01) and Doberman Pinschers (P less than 0.001) had higher prevalence of seizures. Caudal cervical spondylomyelopathy was associated with higher prevalence of seizures, compared with all other diagnoses (P less than 0.001). Seizures were significantly more prevalent when body weight was greater than or equal to 29 kg (P less than 0.001), when greater than or equal to 2 injections of contrast medium were administered (P less than 0.016), or when 2 injections of contrast medium were given at the cisterna magna (P less than 0.015). The 10% prevalence of seizures after myelography with iohexol in the study reported here is greater than in previous reports, but is lower than that reported after myelography using metrizamide. 相似文献
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Cervical intervertebral disc protrusion in two horses 总被引：2，自引：1，他引：1
Foss RR Genetzky RM Riedesel EA Graham C 《The Canadian veterinary journal. La revue veterinaire canadienne》1983,24(6):188-191
Two horses with ataxia of all four limbs were found to have cervical intervertebral disc protrusion. Severe pelvic limb ataxia, proprioceptive deficits and spasticity were present in both horses with similar but less severe signs in the thoracic limbs. Cerebrospinal fluid analysis was within normal limits. Metrizamide myelography allowed definitive diagnosis in one case when a compression of the spinal cord was demonstrated at the level of the second intervertebral space. In the second case, an intervertebral disc protrusion between cervical vertebrae 6 and 7 was found at necropsy. Fiber degeneration with poor myelin staining characterized the spinal cords histologically. 相似文献
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PATRICIA L. ROSE SAMEEH M. ABUTARBUSH WENDY DUCKETT 《Veterinary radiology & ultrasound》2007,48(6):535-538
Standing myelography in the horse has been previously described. In that study, metrizamide was used and significant complications were reported. In recent years, the introduction of less-toxic nonionic contrast media has reduced the incidence of complications. This study was undertaken to determine whether standing myelography using a nonionic contrast medium could provide a diagnostic study and be performed safely in the equine patient. Standing myelography was performed in eight horses. The contrast medium used was iohexol. In five horses a myelogram of diagnostic quality was achieved; in one horse contrast flowed only to the level of C6 and in two horses contrast medium did not reach the cervical subarachnoid space. Owing to the difficulty in achieving good flow of the contrast medium in some horses, this procedure may be of limited utility. However, if puncture of the lumbosacral subarachnoid space can be achieved easily and quickly, standing myelography may be a clinically useful procedure. It may be attempted in cases in which the economic value of the patient makes myelography under general anesthesia impractical. In patients presenting for evaluation of ataxia it may be possible to perform a standing myelogram at the time of CSF sample collection from the lumbosacral space. 相似文献