共查询到20条相似文献，搜索用时 15 毫秒
1.
P. R. BEAUMONT † J- B. O'BRIEN H. L. ALLEN‡ J. A. TUCKER§ 《The Journal of small animal practice》1979,20(1):19-25
An 8-year-old, spayed, female miniature poodle was presented to the University of Pennsylvania Veterinary Hospital (UPVH) with signs of mild respiratory distress related to increasing laryngeal obstruction. The dog was found to have a unicentric mast cell sarcoma involving the larynx, with tumour infiltration of the tissues between the thyroid and arytenoid cartilages as well as subglottic narrowing. Treatment and differential diagnosis are described. 相似文献
2.
Two hundred and forty-four dogs were evaluated for cataracts at the University of Tennessee from January 2001 to December 2002. Fifty-four canine breeds were affected. Odds ratios for cataracts were significantly higher for six purebred dogs (including the cocker spaniel, miniature schnauzer, toy poodle, Boston terrier, miniature poodle, and bichon frise) compared with mixed-breed dogs. One hundred fifty-nine dogs did not have cataract surgery. The most common reason for dogs not having surgery was retinal degeneration (n=66). 相似文献
3.
Yui KOBATAKE Nao NISHIMURA Hiroki SAKAI Syunsuke IWANA Osamu YAMATO Naohito NISHII Hiroaki KAMISHINA 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2020,82(11):1704
A 1-year- and 11-month-old spayed female toy poodle had showed progressive ataxia and paresis in the hindlimbs since 11 months old. Magnetic resonance imaging revealed high signal intensity on T2-weighted and fluid-attenuated inversion recovery images at the thoracic and lumbar spinal cord. The dog’s neurological condition slowly deteriorated and flaccid tetraparesis was exhibited. At 4 years and 11 months old, the dog died of respiratory failure. On postmortem examination, eosinophilic corkscrew bundles (Rosenthal fibers) were observed mainly in the thoracic and lumbar spinal cord. Histological features were comparable to previously reported cases with Alexander disease. This is a first case report to describe the clinical course and long-term prognosis of a dog with Alexander disease. 相似文献
4.
Legg-Calve-Perthes disease in dogs: Genetic aetiology 总被引：1，自引：0，他引：1
R. Robinson 《The Journal of small animal practice》1992,33(6):275-276
The incidence of Legg-Calve-Perthes disease among litters with affected individuals is examined for four of the smaller breeds of dog, with special regard to the West Highland white terrier and the Yorkshire terrier. In these two breeds, the incidence is such to indicate monogenic recessive inheritance of the condition. The symbol pd is proposed for the gene. The available evidence suggests a similar aetiology for the miniature poodle and pug. 相似文献
5.
G N Joiner C J Fraser J H Jardin J M Trujillo 《Canadian journal of veterinary research》1976,40(2):153-160
A case of chronic granulocytic leukemia was diagnosed in a ten year old miniature poodle and was observed for four and one half years. Methods of diagnosis and characteristic features are described. A persistent granulocytosis with a preponderance of mature forms and the absence of a detectable underlying pyogenic process were key diagnostic features which enabled distinction of this neoplastic process from acute granylocytic leukemia and a leukemoid reaction. Other features included dysplastic granulocytes in various developmental stages, marginal anemia and hyperplastic bone marrow (myeloid elements). No blast crisis occurred. This dog was euthanatized in August 1975. 相似文献
6.
An 18-year-old male miniature poodle had a chronic nonproductive cough. On radiographic examination, an opacification resembling a foreign body was noticed within the trachea at the level of the sixth cervical vertebra. When the trachea was examined endoscopically, a circumferential flap-like lesion was found. To differentiate the invagination from an annular mass, thoracic computed tomography (CT) of the trachea was performed. There was cranial displacement and invagination of a tracheal segment creating the flap-like lesion. Tracheal intussusception should be considered as a cause of an annular tracheal mass. 相似文献
7.
A 3-month-old English Cocker Spaniel and a 6-month-old miniature poodle presented with clinical signs related to an abnormal right eye since birth. In both dogs, the right globe could not be identified and was replaced by a fluctuant intraorbital mass covered by a vascularized mucous membrane. Ultrasonography demonstrated that both masses were cystic structures markedly larger in size than the normal contralateral globes. In both cases, surgical excision revealed a multilobular cyst filling the whole orbital cavity. Histopathologic examination and immunostaining for glial fibrillary acid protein and S100 protein supported a diagnosis of neural cysts associated with ocular dysplasia. The definitive diagnosis was congenital cystic eye and microphthalmos with cyst for the Cocker Spaniel and miniature poodle, respectively. Karyotype was normal in both dogs. Congenital cystic eye and microphthalmos with cyst result from defects in early embryonic life that arise following formation of the optic vesicle and prior to closure of the optic fissure. To the authors' knowledge neither has been reported in the canine species. They should be considered in the differential diagnosis of orbital cysts in dogs. 相似文献
8.
Levine JM Bergman RL Coates JR Shelton GD 《Journal of the American Animal Hospital Association》2005,41(4):247-251
A 12-year-old, spayed female miniature poodle was evaluated because of a 4-day history of paraparesis, dysuria, and tenesmus. Neurological assessment suggested peripheral nervous system dysfunction, predominantly pelvic limb weakness with a possible concurrent sixth lumbar (L(6)) to second sacral (S(2)) myelopathy. Further studies supported the diagnoses of myasthenia gravis, hypothyroidism, and meningomyelitis. To the authors' knowledge, this is the first reported case of concurrent myasthenia gravis and meningomyelitis in the dog. It was unclear whether the identified conditions evolved from a shared etiopathogenesis or were merely coincidental. 相似文献
9.
Agg EJ 《The Canadian veterinary journal. La revue veterinaire canadienne》2006,47(7):697-699
A young, male miniature poodle was presented with severe neurological problems. Laboratory tests and ultrasonograph examination were consistent with extrahepatic portosystemic shunts, resulting in hepatic encephalopathy. When surgical correction proved not to be a viable option, the dog was euthanized. Postmortem examination revealed multiple shunts likely acquired after severe hepatitis. 相似文献
10.
W. Heuser 《The Canadian veterinary journal. La revue veterinaire canadienne》1980,21(11):314-316
A miniature poodle was presented with a history of a chronic, insidious hind limb lameness. As part of the clinical approach to the case, a serum electrophoresis was done which revealed a polyclonal hypergammaglobulinemia. Analysis of stife and carpal joint fluid revealed an elevated white cell count, that consisted of about 75% neutrophils and 25% monocytes. The joint fluid was sterile on bacteriological culture. Radiographs of the carpal joints indicated some narrowing of joint spaces and subchondral lucencies. Rheumatoid factor was identified on serological testing. Histopathology of carpal joint biopsies indicated a nonsuppurative synovitis. These findings are consistent with a diagnosis of rheumatoid arthritis. The dog was treated with prednisone on a long term basis. Response to treatment has been good. 相似文献
11.
S. J. Langley-Hobbs 《The Journal of small animal practice》1994,35(12):603-603
A FOUR-year-old spayed miniature poodle was presented for evaluation because of a chronic cough which had been present from eight weeks of age. The condition had gradually worsened until exercise intolerance, inappetence and abdominal breathing occurred. The dog was thin and weighed only 1.5 kg. Auscultation revealed tachycardia, a normal respiratory rate and wheezing noises - more prominent on inspiration and localised to the cervical portion of the trachea. There was marked inspiratory and expiratory effort. Tracheal sensitivity was moderate and palpation induced a dry hacking cough. Radiography demonstrated mild thickening of the bronchial wall and pulmonary hyperinflation. Expiratory/inspiratory radiographs failed to demonstrate dynamic tracheal collapse. On fluroscopy, substantial changes in tracheal calibre were not apparent. Bronchoscopy was performed and the tracheal lumen was normal up to 12.5 cm from the incisors. At this point, there was lateral tracheal collapse to about 30 per cent. There was dynamic collapse with respiratory effort. The bronchoscope could be passed beyond the narrowing (consisting of five tracheal rings) to a trachea of normal size. No pathogens were found on tracheal lavage. Surgery was undertaken through a midline, ventral approach. Six specially made tracheal ring prostheses were individually inserted around the trachea and inside the recurrent laryngeal nerve. Each prosthesis was sutured in four places to the tracheal ring, to give external support. The dog improved clinically and 11 months after surgery, bronchoscopy was again performed. The trachea was narrowed to approximately 60 per cent but there was no dynamic collapse of the airway. Twenty-seven months after surgery the dog continued to lead a healthy active life. 相似文献
12.
Myung-Chul KIM JaeMyung KIM WoonKi KANG Yunho JANG Yongbaek KIM 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2016,78(1):157-160
A 3-year-old neutered female poodle with a long history of dermatophytic skin disease was
presented with lethargy, anorexia and progressive weight loss. Abdominal ultrasonography
revealed markedly enlarged mesenteric lymph nodes and multiple hypoechoic foci in the
spleen. Cytology of the mesenteric lymph nodes and spleen showed granulomatous
inflammation with fungal organisms and negatively stained intracytoplasmic bacterial rods
consistent with Mycobacteria spp. Based on culture, multiplex polymerase
chain reaction and sequence analysis, the bacterium was identified as
Mycobacterium avium subspecies hominissuis. Despite treatment with
antibiotics, the dog’s condition deteriorated, and it died approximately 3 weeks after
first presentation. 相似文献
13.
Bley CR Stankeova S Sumova A Hilbe M Kaser-Hotz B 《Schweizer Archiv für Tierheilkunde》2003,145(2):89-94
Palliative radiation therapy may provide significant relief in symptoms in pets with incurable cancer. Therapy is applied over a short period of time, using larger than normal fractional doses. Palliative radiation leads to minimal or no side effects. This case report describes the situation of a miniature poodle that was presented with severe dyschezia as well as fresh blood in the feces. The dog had a large abdominal mass which was diagnosed as lymph-node metastasis of a perianal gland carcinoma. Therapy included palliative radiation as well as chemotherapy. Six months after initial presentation the dog is free of clinical symptoms. 相似文献
14.
A 3.5-year-old intact female miniature poodle (weighing 2.7 kg) was referred to the Veterinary Teaching Hospital at Kangwon National University, because of inadvertent aortic embolization, by an occlusion coil used for the closure of patent ductus arteriosus (PDA). The coil was found at the site of the branching renal arteries in the abdominal aorta. A foreign body forceps with a three-wire nail tip was used, with fluoroscopic guidance, to retrieve the coil. After the removal, the dog was treated with heparin to prevent thromboembolization. 相似文献
15.
16.
Hesam A. Seifi DVM DVSc Hooshang Gray DVM Mehrdad Mohri DVM DVSc Arya Badiee DVM DVSc 《Journal of Equine Veterinary Science》2002,22(5)
The susceptibility of Caspian miniature horses to hyperlipidemia was followed in a study of healthy Caspian miniature horses in which food but not water was withheld for 48 hours. Two months before the study, the horses were fed a high-energy diet. The mean of weight gain was 26.46 kg per horse during this period. All horses had a normal rectal temperature, respiratory rate, and pulse throughout the experiment. During the period of food deprivation, levels of serum triglyceride, aspartate aminotransferase, and alanine aminotransferase significantly (P < .05) increased and glucose concentration decreased. As a conclusion, Caspian miniature horses were susceptible to hyperlipidemia, but they did not show classic hyperlipemia syndrome. 相似文献
17.
Bama miniature pigs, which are local high-quality species of China, have the advantages of genetic stability, ideal hair distribution, microsomatia, prolificacy, low fodder demand, strong disease resistance, and they are similar to human beings in aspects of physiology, anatomical structure, drug metabolism, biochemical indicators, disease mechanism, etc. Bama miniature pigs have been used in the wide fields of medical research, such as cardiovascular system, skin plastic, endocrine and metabolism, digestive system, oral medicine, heterograft, Chinese medicine, anesthesiology, nervous system, etc., and been applied to establish the animal models which are similar to human diseases, such as myocardial ischemia, coronary micro-embolization, atrial septal defect, atherosclerosis, skin injury, transdermal drug, metabolic syndrome, diabetes mellitus and complications, obstructive jaundice, chronic pancreatitis, liver cirrhosis, liver radiofrequency ablation, periodontal tissue inflammation, mandibular defect, heterogeneous organ/cell transplantation, syndrome of Chinese medicine, anesthesia, cerebral ischemia, stent implantation, shock, etc. Bama miniature pigs, as an ideal experimental animal, have broad application prospects in biomedical research.In this article,we mainly summarized the progress of Bama miniature pigs in the field of medicine, to understand the types, construction methods and pathological characteristics of Bama miniature pigs disease models, which contribute to further explore the specific etiology, pathogenesis, complications, prevention and control measures, etc., and laid the scientific foundation for expanding the research scope and improving the medical level. 相似文献
18.
Severe equine asthma (SEA) syndrome is a chronic recurrent respiratory disease, common among adult horses. The disease occurs in genetically susceptible individuals after their exposure to organic dust. Thus, environmental management has proved essential in controlling airway challenge and disease exacerbation. This is a demanding process that can only be achieved through the horse owners’ cooperation. One year after initial diagnosis of SEA in a group of 39 horses, owner compliance to an environmental management protocol was evaluated. The overall compliance to the protocol was poor and the horses’ clinical health and need for pharmacological management was related to the successful implementation of the environmental recommendations provided on disease diagnosis. 相似文献
19.
巴马小型猪动物模型在医学领域的研究进展 总被引：1，自引：0，他引：1
巴马小型猪是中国原产地闭锁繁殖的优质品种,具有遗传稳定性、理想的毛色分布、体型小、多产性、饲养要求低、抗病力强等优势,且在生理学、解剖结构、药物代谢、生化指标和疾病发生机制等方面与人类相似,已用于心血管、皮肤整形、内分泌及代谢、消化、口腔医学、异种移植、中医、麻醉学、神经系统等广泛医学领域的研究,建立了心肌缺血、冠脉微栓塞、卵圆孔未闭、动脉粥样硬化、皮肤创伤、经皮给药、代谢综合征、糖尿病及其并发症、梗阻性黄疸、慢性胰腺炎、肝硬化、肝脏射频消融、牙周组织炎症、下颌骨缺损、异种器官/细胞移植、中医征候、手术麻醉、脑缺血、支架植入、休克等一系列类似于人类疾病的动物模型,表明巴马小型猪作为理想的试验动物在生物医学研究中具有广阔的应用前景。作者综述了巴马小型猪作为试验动物在各医学领域的应用进展,了解现有巴马小型猪疾病模型的种类、构建方法及病理特征,有助于进一步探索具体的病因、发病机制、并发症和防制手段等,为拓展研究范围、提高医学水平奠定了科学基础。 相似文献
20.
Since the first publication on “regional ileitis”, the relevance of this chronic inflammatory disease condition termed finally as Crohn's disease is continuously increasing. Although we are beginning to comprehend certain aspects of its pathogenesis, many facets remain unexplored. Host's gut microbiota is involved in a wide range of physiological and pathological processes including immune system development, and pathogen regulation. Further, the microbiome is thought to play a key role in Crohn's disease. The presence of Crohn's-associated variants of NOD2 and ATG16L genes appears to be associated not only with alterations of mucosal barrier functions, and bacterial killing, but the gut microbiota, as well, reflecting a potential relationship between the host's genotype and intestinal dysbiosis, involved in disease etiology. This review aims to characterize some exciting new aspect of Crohn's disease pathology, focusing mainly on the role of intestinal microbes, and their interplay with the immune system of the host. 相似文献