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1.
S I Reinke A A Stannard P J Ihrke J D Reinke 《Journal of the American Veterinary Medical Association》1987,190(1):57-60
The skin of 17 dogs with pyotraumatic dermatitis was studied microscopically. Two patterns were seen. The first pattern was a superficial, ulcerative, inflammatory process of undetermined cause and pathogenesis. Current recommended treatment, which includes corticosteroids, was believed to be appropriate for such lesions. The second pattern, suppurative folliculitis, was considered to be localized pyoderma. Dogs with severe folliculitis were believed to represent those cases of pyotraumatic dermatitis in which the response to corticosteroid treatment has been poor. It was concluded that antibiotics should be used for treating pyotraumatic dermatitis with suppurative folliculitis, in lesions responding poorly to treatment with corticosteroids, or possibly in any severe lesion of pyotraumatic dermatitis, especially in Golden Retrievers and Saint Bernards. 相似文献
2.
D G Wilson M B Mays P T Colahan 《Journal of the American Veterinary Medical Association》1989,194(12):1721-1723
Seven horses with canker had radical surgical debridement and various irritant substances applied to the wounds. Four of the horses were clinically normal in (mean) 3.6 months, 1 mare was lame, and 2 horses were euthanatized because of complications of their treatments. Seven horses that had minor surgical debridement and antimicrobial agents used systemically and topically were clinically normal in (mean) 1.4 months. Seemingly, canker in horses should be managed using minor surgical debridement and appropriate antimicrobial therapy. 相似文献
3.
Hoof disease and injuries are common and serious problems for equines. Maggot debridement therapy (MDT) has been used to treat problematic wounds in humans, but has been used only rarely in other animals. US veterinarians who had employed MDT were surveyed to investigate their reasons for the choice of this treatment and their clinical experiences with it. Between 1997 and 2003, 13 horses were treated by eight veterinarians who used MDT to control infection or debride wounds, which could not easily be reached surgically or were not responding to conventional therapy. Seven animals were lame, and six were expected to require euthanasia. Following maggot therapy, all infections were eradicated or controlled, and only one horse had to be euthanased. No adverse events were attributed to maggot therapy for any of these cases, other than presumed discomfort during therapy. The data collected suggest that maggot therapy could be useful for treating some serious equine hoof and leg wounds. 相似文献
4.
脓皮病是由化脓性细菌感染引起的皮肤化脓性疾病,又称为化脓性皮炎。根据致病原因可分为原发性的和继发性脓皮病。本文所描述的就是一例由真菌和螨虫混合感染后继发性脓皮病。在治疗过程中,根据病情和药敏试验的结果,调换局部涂抹和全身抗菌消炎的药物,取得了满意的效果。 相似文献
5.
Claude M Nagamine Fernando Castro Ben Buchanan James Schumacher Linden E Craig 《Journal of veterinary diagnostic investigation》2005,17(3):269-271
Spirochetes were identified histologically in canker (proliferative pododermatitis) in 3 horses. The data suggest that spirochetes may contribute to the pathology of equine chronic foot diseases similar to the manner in which they contribute to the pathology of bovine papillomatous digital dermatitis and contagious ovine digital dermatitis. 相似文献
6.
A 9‐year‐old, castrated male, miniature schnauzer presented with malaise, anorexia, fever and severe inflammatory skin lesions on the dorsum, thighs and pinnae. The lesions developed 2 days after bathing with a commercial shampoo. Histopathological examination of skin samples revealed neutrophilic exocytosis, parakeratosis, epidermal hyperplasia and neutrophilic infiltration in the superficial dermis. Skin lesions resolved completely after 14 days of treatment with prednisolone and ofloxacin. Patch testing performed on the patient and a clinically healthy dog showed erythema at the site exposed to the culprit shampoo 48 h later only on the patient. Histopathological findings of the erythematous reaction were similar to those of the spontaneous skin lesions. Based on these findings, the dog was diagnosed with superficial suppurative necrolytic dermatitis of miniature schnauzers. The patch test results suggested that contact dermatitis to a commercial shampoo played a role in the pathogenesis of this disease. 相似文献
7.
A 15-year-old domestic shorthair cat was evaluated for an acute onset of jaw swelling and anorexia. A small area of skin discoloration, left mandibular subcutaneous soft swelling and dehydration were noted on physical examination. Fine needle aspirate findings of the mass were compatible with an abscess. After 8 hours of supportive and antimicrobial treatment, a large area of necrotic skin was noted. The cat was taken to surgery and an aggressive debridement was performed. The histopathology findings were compatible with necrotising fasciitis and dermatitis. 相似文献
8.
M. Oosterlinck K. Deneut M. Dumoulin F. Gasthuys F. Pille 《Equine Veterinary Education》2011,23(9):466-471
The medical records of 30 horses (18 Warmbloods, 7 draught horses, 3 other breeds and 2 of unknown origin) with chronic proliferative pododermatitis (canker) were reviewed and long‐term outcome was obtained by telephone questionnaire. In 28/30 cases, the owner was the first to discover the problem. The disease was initially recognised as canker in only 5/28 cases, whereas in 10/28 cases a treatment for thrush had been continued for several months before referral. There was a similar prevalence in the fore (41) and hind (44) hooves; 13/30 horses had 4 hooves affected. Treatment consisted of surgical debridement and hoof care. Duration of hospitalisation was significantly decreased in horses receiving oral prednisolone for 3 weeks compared to those without this additional systemic treatment (mean ± s.d. 24 ± 5 days, n = 7 vs. 40 ± 19 days, n = 19, respectively). Long‐term follow‐up ranged from 3 months to 6 years (36 ± 22 months) and was available for 24 horses. No recurrence was reported in 10 horses. In 14 horses problems recurred within the first year, and 6 had been subjected to euthanasia for this reason specifically, whereas the others were managed by regular trimming. There was no significant association between recurrence and the number of affected hooves or the use of any systemic treatment. Horses with delayed referral because of preceding treatments had significantly more chance to develop recurrence, highlighting the need for prompt diagnosis and subsequent treatment. 相似文献
9.
Emergence of amantadine-resistant H5N2 avian influenza virus during a simulated layer flock treatment program 总被引：3，自引：0，他引：3
An experiment was designed to simulate field conditions in which preventive treatment is not initiated until after some chickens in a flock are infected with avian influenza (AI). Twelve hens began to receive amantadine hydrochloride on the day they were inoculated (day 0) with highly pathogenic AI virus, A/chicken/Pa/1370/83. These hens remained clinically normal through 8 days postinoculation (PI), but five died after day 9; mean death time (MDT) was 18 days. Three of 12 hens given amantadine beginning 1 day PI died (MDT 5.4 days), seven of 12 hens given amantadine beginning 3 days PI died (MDT 3.7 days), and all 12 inoculated hens not given amantadine died (MDT 4.9 days). The delayed mortality in the day 0 treatment group was likely due not to the original inoculum but to the emergence of a drug-resistant virus population. Virus isolated from a dead hen from that group was resistant to the actions of amantadine in both in ovo and in vivo tests. The lack of late mortality due to the drug-resistant virus in the day 1 and day 3 treatment groups, which were in close contact with the day 0 treatment group, was attributed to their becoming infected before treatment with the drug and to the development of protective immunity. 相似文献
10.
Jongbloets AM Sloet van Oldruitenborgh-Oosterbaan MM Meeus PJ Back W 《Tijdschrift voor diergeneeskunde》2005,130(4):106-109
Equine canker is a chronic, hyperplastic, exudative pododermatitis affecting one or more feet. Although many causes and treatments have been suggested, the cause of the disease is still unknown and most probably multifactorial. Local treatments include radical surgical debridement of the diseased hoof tissue and application of caustic substances, antibiotics, and pressure bandaging. Nevertheless, the number of recurrences is high (45%). This article presents a 3-year-old New Forest pony-cross mare in which all horny structures (frogs, coronets, spurs, chestnuts) of all feet were affected. Bacteriological and fungal cultures of the frogs were found negative for the pathogens tested. Papilloma virus was not found. Clinical findings raised the hypothesis that the non-specific hyperplastic inflammation of these horn-like structures might have been caused by an (auto-)immune reaction. On the basis of the clinical findings, the pony was treated with surgical debridement of the frogs of a diagonal pair of feet and oral administration of prednisolone (1 mg/kg sid). The frogs, coronets, spurs, and chestnuts of all four feet healed completely within 8 weeks, thus making an (auto-)immune reaction more likely. In conclusion, this case report raised the hypothesis that an aspecific, hyperplastic inflammation of all four feet ('equine canker') and other horny structures may be caused by an (auto-)immune reaction, and that corticosteroids (prednisolone 1 mg/kg sid per os) are effective as treatment. 相似文献
11.
Prevalence of lameness and of associated claw disorders in Greek dairy cattle industry 总被引：1，自引：0，他引：1
The aim of this study was to assess the prevalence of lameness as well as the prevalence of claw–horn disruptions, abnormal claw shape and dermatitis in lame cows in Greek dairy farms and to evaluate their risk factors. Forty dairy farms were visited twice, during winter and during summer, and the lameness of milking cows was scored using a 5-point scale. In total 760 cows were lame (lameness score ≥ 3) and were further examined to identify macroscopically the claw disorders. The herd size, the trimming and footbathing frequency, the floor surface, the cleanness of the herd, the scraping frequency and the disinfectant used in the footbaths were recorded. The mean lameness prevalence was 18.7% and that of claw disorders observed in the lame cows was 75.4% for abnormal claw shape, 30.2% for dermatitis and 30.6% for claw–horn disruptions. Large herd size and the absence or only once per year trimming were associated with increased risk for the presence of lameness. 相似文献
12.
A two-year-old Swiss Braunvieh cow was referred to our clinic because of tenesmus and weight loss. Clinical examination revealed a moderately abnormal general behaviour and condition, thin body condition and a rectal temperature of 40.1 degrees C. Tenesmus was evident, and rumen and intestinal motility were markedly reduced. All tests for a reticular foreign body were positive. On rectal examination, a round, smooth, firm, non-painful mass with a diameter of approximately 15 cm was palpated far cranially on the right side. Abnormal haematological and biochemical findings included marked anaemia, neutrophilic leucocytosis, markedly elevated concentration of fibrinogen and mildly elevated gamma-glutamyl-transferase activity. The clotting time of the glutaraldehyde test was one minute. Ultrasonographic examination revealed abscesses involving the liver and extending caudally into the right flank region. The liver parenchyma had diffuse changes. Because of a grave prognosis, the cow was euthanized. Postmortem findings substantiated ultrasonographic results; there were abscesses, caused by Fasciola hepatica infestation, originating in the liver and extending into the right flank. As well, there was severe, bilateral, multifocal, suppurative nephritis due to thromboembolism. Based on all the findings, a diagnosis of liver abscess caused by fascioliasis and bilateral suppurative nephritis was made. 相似文献
13.
Objective: To report clinical signs and management of hypospadias in a horse. Study Design: Clinical report. Animal: A 6‐year‐old, Friesian gelding. Methods: Partial phallectomy was performed to resolve contact dermatitis of the pelvic limbs and abnormal behavior during urination. Subsequent urethral meatal stenosis was treated by revision. Results: Hypospadias and chordee caused altered direction of urine flow, contact dermatitis of the pelvic limbs, and abnormal behavior. Partial phallectomy and subsequent revision after meatal stenosis resolved urine direction, flow and abnormal behavior. Conclusions: Abnormalities of the urinary tract associated with hypospadias can result in urine‐induced, contact dermatitis and distress during urination, but these complications can be resolved by partial phallectomy. 相似文献
14.
15.
Dermatitis with intradermal cilated protozoa was identified in 18 of 95 (19%) Atlantic Bottlenose Dolphins (Tursiops truncatus) that died during the 1987-1988 Atlantic-dolphin morbillivirus epizootic. The lesions were characterized by focally extensive suppurative and histiocytic dermatitis and cellulitis with ulceration and variable numbers of dermal and hypodermal ciliates. Vasculitis, thrombosis, and/or intravascular ciliates were rarely present. In one dolphin, there was an associated lymphadenitis with ciliates, and in another, bronchopneumonia with rare intrabronchiolar ciliates. Ten of the dolphins were female, and eight were male. The animals ranged in length from 148 to 260 cm. Eleven were from Virginia, four were from New Jersey, and three were from Florida. In 13 dolphins, results of immunohistochemical and/or polymerase chain reaction (PCR) tests were positive for morbillivirus infection. Results of immunohistochemical tests were negative in four dolphins that were not also tested with PCR. Results were also negative in one dolphin tested using both methods. Nine dolphins had concomitant bacterial, fungal, and/or other protozoal infections. Fourteen other dolphins with ciliate-associated dermatitis were identified from 414 Atlantic bottlenose dolphin cases (3%) archived at the Armed Forces Institute of Pathology. The incidence of dermatitis with invasive ciliates is much greater in dolphins that died during the 1987-1988 epizootic. 相似文献
16.
为了研究叶片微结构特征与柑橘溃疡病抗性的关系。选用罗浮金柑、新生系3号椪柑、纽荷尔脐橙及星露比葡萄柚这四个分别被认为是对柑橘溃疡病具有高抗、抗、耐和高感特性的品种,通过涂抹接种法来在实验室验证其抗病性;采用扫描电镜及树脂包埋半薄切片等技术对上述品种的成熟叶片下表皮气孔及叶片显微解剖结构进行观察测量;将健康叶片浸泡在菌液中,采用细菌分离法来观察同样条件下通过气孔进入不同柑橘品种叶片体内的活细菌数。结果：四个品种对溃疡病抗性存在显著差异;不同品种间气孔密度、气孔大小、叶片厚度、栅栏组织厚度、海绵组织厚度、下皮层厚度也存在差异,其中气孔密度差异达到极显著;健康叶片浸泡接种溃疡病后,分离到的单菌落数的顺序依次是星露比葡萄柚>纽荷尔甜橙>新生系3号碰柑>罗浮金柑。因此,气孔密度对柑橘品种抗病性的解释量极高。 相似文献
17.
The prevalence of hoof lesions and lameness in 4899 heifers and cows was determined at claw trimming one time in a cross-sectional study on 101 Swedish dairy farms, 1996-1998. The percentage of affected animals was 41% for heel-horn erosion, 30% for sole haemorrhages, 27% for erosive dermatitis, 21% for abnormal claw shape, 14% for white-line haemorrhages, 8.8% for white-line fissures, 8.6% for sole ulcers, 3.3% for double soles, 2.3% for verrucose dermatitis, and 1.8% for interdigital hyperplasia (IH). Seventy-two percent of all animals had at least one hoof lesion. The prevalence of lameness was 5.1%; most hoof lesions did not cause lameness. Differences between herds were substantial; the herd-specific, animal-level prevalence of lesions ranged from 25 to 98% and of lameness from 0 to 33%. Sole haemorrhages were found in all herds. The proportion of variance at the between-herd level was particularly high for heel-horn erosion (62%) and abnormal claw shape (54%). Strong correlations between lesions were found within hooves (and animals), e.g. for heel-horn erosion and dermatitis (Spearman's rank correlation, r(s)=0.36 and 0.37, respectively) and for sole and white-line haemorrhages (r(s)=0.25 and 0.28). Most hoof lesions affected hind and front hooves bilaterally, whereas the correlation between hind and front hooves generally was lower. Herds that ranked high for prevalence of sole ulcer also ranked high for sole haemorrhages and for abnormal claw shape and herds that ranked high for dermatitis also ranked high for heel-horn erosion, verrucose dermatitis and IH. Abnormal claw shape was strongly associated with sole ulcer (r(s)=0.41 at cow level)-suggesting the importance of maintaining a correct claw shape for the prevention of hoof-horn lesions. 相似文献
18.
A randomized, double-blind, placebo-controlled trial of P07P, a product derived from a traditional Chinese herbal remedy, was undertaken in 50 dogs with atopic dermatitis. Owners recorded a daily itch score for 4-14 days before treatment and during treatment. Packets of powder containing P07P or placebo were added to the food once daily for 8 weeks. Dogs were assessed for erythema, surface damage, overall coat condition and seborrhoea by the same investigator, as well as for pruritus and general demeanour, at 0 (visit 2), 28 (visit 3) and 56 (visit 4) days of treatment or at withdrawal. Investigator and owner assessments of response were recorded after 28 and 56 days of treatment or at withdrawal. The predefined primary outcome measure was the owners' assessment of response at the end of treatment. Nine of the 24 dogs (37.5%) in the P07P group but only 3 of the 23 dogs (13%) in the placebo group were considered to have improved, but this difference was not statistically significant (P = 0.09). There was a significantly higher withdrawal rate due to worsening of condition in the placebo group (P = 0.04). Mean daily itch score in the second 28-day period of the study was significantly higher than baseline in the placebo group (P = 0.01) but not in the P07P group (P = 0.30). Pruritus scores showed a significant deterioration from baseline at the final visit in the placebo group (P = 0.01) but not in the P07P group (P = 1.00). There was a significant difference between the groups in change from baseline in erythema score at visit 3 (P = 0.05). There were no significant differences (P > 0.05) in surface damage, seborrhoea, overall coat condition and general demeanour scores within or between the groups throughout the study. The product was well tolerated with no severe or serious adverse events recorded. P07P may be beneficial as a novel nonsteroidal therapy for the management of dogs with atopic dermatitis. 相似文献
19.
Brandt S Schoster A Tober R Kainzbauer C Burgstaller JP Haralambus R Steinborn R Hinterhofer C Stanek C 《Equine veterinary journal》2011,43(2):202-209
Reasons for performing the study: Equine hoof canker is a chronic proliferative pododermatitis of as yet unknown aetiology. Like equine sarcoid disease, canker is a therapy‐resistant disorder characterised by hyperkeratosis, acanthosis and a marked tendency to recur. Hypothesis: There is an association of sarcoid‐inducing bovine papillomaviruses of types 1 and 2 (BPV‐1, BPV‐2) with hoof canker disease. Methods: Using PCR‐based techniques, we assessed canker tissue, intact skin and/or peripheral blood mononuclear cells (PBMCs) of 25 canker‐affected horses for the presence of sarcoid‐associated BPV‐1 and ‐2. Results: Conventional PCR revealed BPV‐1/‐2 DNA in 24/24 canker, 12/13 skin and 10/11 PBMC DNA isolates. Using inverse PCR, full‐length BPV episomes were detected in 1/5 canker specimens. Sequencing of viral early and late genes amplified from canker, intact skin and PBMC DNA of 2 cases revealed an overall identity of 98% to BPV‐1. Viral DNA loads amounted to ≤16 copies per cell in canker tissue and intact skin, and to ≤0.35 copies per PBMC, as determined by quantitative PCR. Using RT‐PCR, the viral major oncogene E5 was shown to be transcribed in 2/4 canker tissue specimens and 5/7 PBMC isolates. Immunocapture PCR from 7 canker and 6 skin extract supernatants revealed capsomere‐associated viral DNA in one canker and one skin sample. Hoof tissue, skin and PBMCs collected from 13 individuals with no signs of canker or BPV‐related malignancies scored negative throughout the experiments. Conclusion: These findings suggest that the observed presence of BPV‐1/‐2 in canker‐affected horses is not coincidental but indicative of an active contribution to hoof canker disease. Potential relevance: The use of antivirals and/or immune modulators may help improving canker therapy. 相似文献
20.
羊传染性脓痂皮炎又被称为羊传染性脓疱病、羊口疮病,是由羊传染性脓疱病毒感染引发的一种急性接触性传染性疾病。羊养殖主产区均有发生,是一种常见疾病。羊传染性脓痂皮炎虽然造成的死亡率较低,但是会严重影响羊群正常采食,造成营养物质供给不足,身体逐渐消瘦,抵抗能力变差,易继发感染多种传染性疾病,表现出复杂的临床症状,威胁羊群健康。 相似文献