共查询到20条相似文献，搜索用时 31 毫秒
1.
Yániz JL Santolaria P Rutllant J López-Béjar M López-Gatius F 《Anatomia, histologia, embryologia》2000,29(3):149-155
This study was undertaken to describe the surface features of the peritoneal mesothelium covering the genital tract and adjacent ligaments of the cow during the oestrous cycle. The relationship between mesothelial surface and spermatozoa was also evaluated after intra-uterine and intraperitoneal insemination. Surface features of mesothelial cells from 25 cyclic cows were examined by scanning electron microscopy and by image analysis. Presence of spermatozoa was evaluated by scanning electron microscopy in seven additional cows. In the external side of the infundibulum, the oviductal mucosa exceeds the free margin, forming a continuous band measuring 2.5-10 mm in width. This oviductal epithelium shows cyclical variations with a predominance of ciliated cells during the follicular phase. In respect of the mesothelium, no clear morphological differences were observed associated with the side of ovarian bursa (internal versus external), or with the phase of the oestrous cycle. Mesothelial cells covering the uterus and mesometrium have a higher microvilli density and length and a smaller cell surface area than in the oviduct and adjacent structures. The presence of solitary cilia in the mesosalpinx and mesotubarium superius (infundibulo-cornual ligament) of some specimens was also observed. When samples were processed without postfixation in osmium tetroxide, a layer of amorphous material covered all surfaces. After intra-uterine insemination of five cows, no spermatozoa were found on their peritoneal mesothelium. Numerous spermatozoa were found after intraperitoneal insemination being attached throughout mesothelial surfaces. These results indicate that there are morphological differences between regions, but no cyclic changes, in the surface features of mesothelial cells covering the genital tract and adjacent ligaments of the cow, and that spermatozoa can bind to mesothelial surfaces after intraperitoneal insemination. 相似文献
2.
Kang BC Lee YS Lee SK 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2004,66(12):1617-1619
A spontaneous pleural mesothelioma was observed in a 4-year-old female woodchuck (Marmota monax). At necropsy, multifocal, tan to white, firm discrete nodules, 2 to 40 mm in diameter, were scattered over the ventral parts of the lungs and their corresponding parts of the diaphragm and the thoracic wall. Histopathologically, the tumor cells were large, cuboidal-shaped and variable size, and were weakly positive with PAS and Alcian blue. Immunohistochemically, neoplastic cells were positive for both vimentin and cytokeratin, indicating mesothelial origin. This report represents, as far as we know, the first reported case of a spontaneous mesothelioma in woodchucks. 相似文献
3.
Takasu M Shirota K Uchida N Iguchi T Nishii N Ohba Y Maeda S Miyazawa K Murase T Kitagawa H 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2006,68(5):519-521
We encountered an extremely rare tumor, a pericardial mesothelioma, in a neonatal calf. The patient calf showed severe abdominal distention, and died immediately after birth. The thoracic cavity was contained a huge heart with a large amount of pericardial fluid. A number of granular and cobblestone-like nodules were dispersed over the epicardium and pericardium. The nodules consisted of papillary proliferations of neoplastic cells, and the neoplasm occasionally showed mesenchymal proliferations. Immunohistochemistry revealed that they had the characteristics of mesothelial cells (cytokeratin-and vimentin-positive), and the neoplasm was diagnosed as mesothelioma. 相似文献
4.
Hermeyer K Seehusen F Gehlen H Peters M Wohlsein P 《Berliner und Münchener tier?rztliche Wochenschrift》2010,123(9-10):422-424
Cutaneous malignant lymphomas are rare in horses and comprise predominantly T-cell-rich B-cell lymphomas. They are characterized by multiple tumour nodules affecting predominantly female horses with a survival rate of months to years. At the final stage, metastases to regional lymph nodes occur, whereas widespread organ involvement is rarely reported. In this case report, a cutaneous T-cell-rich B-cell lymphoma in a 7-year-old standardbred gelding with metastases is described. Clinically, multiple cutaneous and subcutaneous nodules, enlarged superficial lymph nodes, rapid weight loss, and ventral oedema were observed. In addition to the clinical findings, necropsy revealed tumour infiltration in multiple body lymph nodes, a solitary pleural mass, and few pulmonary and intestinal tumour nodules. Microscopically, all neoplasms were composed of a densely packed cell population consisting of large lymphoblastic cells expressing CD79a, and numerous small, round, CD3-positive T lymphocytes. With respect to these findings the diagnosis of a cutaneous T-cell-rich B-cell lymphoma with metastases was made. 相似文献
5.
Deciduoid mesothelioma is a rare variant of epithelial mesothelioma, up to now only described in human pathology, which bears remarkable cytomorphologic resemblance to the endometrium of pregnancy, termed decidua. A case of peritoneal mesothelioma with deciduoid features in a 10-year-old, female dog is reported. Multiple whitish-gray nodules (1-5 mm in diameter) in parietal peritoneum and mesentery were histologically composed of large, proliferating, polygonal or ovoid cells with an abundant eosinophilic, glassy cytoplasm. Immunohistochemical evaluation indicated that the neoplastic cells coexpressed cytokeratin and vimentin with strong and diffuse cytoplasmic staining, and ultrastructural analysis showed long and slender mesothelial-type microvilli; these findings confirmed the mesothelial origin of the tumor. 相似文献
6.
野生黄鼬消化管组织结构的观察 总被引：1，自引：1，他引：0
通过组织学观察,探讨野生黄鼬消化管的组织结构特点.将8只野生黄鼬经乙醚麻醉后处死,解剖取食管、胃、小肠、大肠,制作石蜡切片,观察其组织结构.结果显示野生黄鼬食管的黏膜为复层扁平上皮,食管腺发达,肌层以骨骼肌为主.胃贲门部有发达的皱襞和贲门腺;胃底腺有大量的主细胞和壁细胞;胃大弯部的腺体以壁细胞为主,仅有少量主细胞;胃幽门部有发达的幽门腺和大量壁细胞.十二指肠黏膜层有小肠腺,内有潘氏细胞存在,黏膜下层含有十二指肠腺;空肠可见孤立淋巴小结、弥散淋巴组织及集合淋巴小结.结肠无皱襞和肠绒毛,大肠腺排列紧密,其中杯状细胞特别多;直肠固有膜内有发达的大肠腺.所以野生黄鼬消化管的特点是胃各部胃腺发达,壁细胞特别多. 相似文献
7.
In the bovine, the lingual tonsil is localized at the lingual radix. However, as the expansion of the tonsillar tissue was presumed to be much larger than the macroscopically visible part, selected specimens from the bovine tongue were examined to clarify if lymphatic tissue of the lingual tonsil was present rostral of a defined macroscopical landmark, i.e. rostral of the most caudal of the papillae vallatae. The identification of the lymphoreticular system was validated by means of the detection of reticulum cells, especially follicular dendritic cells (FDC). They characterize the tonsillar lymph nodules and distinguish them structurally from unspecific accumulations of lymphocytes. In our study, two monoclonal antibodies, i.e. CNA.42 and D46, detected bovine FDC cells in situ. 'Organized' lymphoid tissue--i.e. solitary lymph nodules and aggregations of lymph nodules, both either with or without surrounding connective tissue, and with or without crypts, but with immunopositive reactions for FDC--could be observed up to 30 mm rostral of the most caudal of the papillae vallatae. As these formations were not identified macroscopically, they shall be referred to as the disseminate part of the lingual tonsil. 相似文献
8.
Andrew H. Schlueter Shannon D. Dehghanpir Bonnie Boudreaux Christopher Robinson Jose Cesar Menk P. Lima Ingeborg M. Langohr 《Journal of veterinary diagnostic investigation》2021,33(4):753
Mesotheliomas are uncommon neoplasms that arise from mesothelial cells in either the abdominal or thoracic cavities and are rarely diagnosed in cats. A 10-y-old spayed female domestic shorthair cat was presented to the Louisiana State University oncology service for evaluation of a large amount of abdominal effusion. Abdominal ultrasound identified a large mesenteric mass with numerous ill-defined nodules. An abdominocentesis was performed with cytologic and immunocytochemical findings consistent with a neoplastic effusion, with large clusters of epithelioid cells that exhibited strong cytoplasmic expression of pancytokeratin, vimentin, and Wilms tumor 1 antigens. Further testing was declined, and meloxicam was prescribed until the cat died 23 d after initial presentation. Upon postmortem examination, the omentum was contracted into a firm mass adhered to multiple organs and accompanied by numerous small white nodules throughout the abdominal cavity. On histopathology and immunohistochemistry, neoplastic cells were found throughout the abdominal cavity; 60–95% exhibited moderate-to-strong cytoplasmic immunoreactivity for cytokeratin, vimentin, and Wilms tumor 1 protein. The final diagnosis was an epithelioid mesothelioma. Our case illustrates the utility of cytology, immunocytochemistry, and its relation to histology and immunohistochemistry. We also reviewed the reported cases of feline mesothelioma. 相似文献
9.
Cells in the peritoneal fluid from 159 horses were examined in Giemsa stained preparations using light microscopy. Normal mesothelial cells showed an oval nucleus with finely reticular chromatin and pale blue cytoplasm. Activated mesothelial cells occurred in fluids derived from mesothelium under acute or subacute, non-septic stimulus and were remarkable for their pleomorphism and intense basophilia which may mimic neoplasia. Transformed mesothelial cells seen in chronic inflammatory fluids were sometimes phagocytic and showed conspicuous cytoplasmic vacuolation. 相似文献
10.
The morphology and behavior of feline cutaneous mastocytomas 总被引：1，自引：0，他引：1
Correlation of histopathology with the behavior of cutaneous mastocytomas in 85 cats revealed two distinct histologic subtypes which were predictive of biologic behavior. The first subtype comprised 65 cats of various breeds which had solitary, discrete, dermal tumors composed of slightly atypical mast cells. Most tumors in this group were histologically and behaviorally benign. However, seven solitary tumors with marked anisocytosis and mitotic activity recurred or spread to other sites within 2 to 3 months. The second subtype occurred in 18 cats which had discrete subcutaneous nodules composed primarily of histiocyte-like cells with equivocal cytoplasmic granularity after staining with toluidine blue. They were identified as mast cells by electron microscopy. Seventeen of the 18 affected cats were Siamese. The histiocytic mastocytomas occurred predominantly in young cats (less than 4 years) and were usually multiple. In the four cats of this group for which we have prolonged follow-up data, the tumors underwent apparently spontaneous regression within 2 years of initial tumor detection. Two other cats had tumors which contained mixtures of mast cell and histiocytic morphologies. 相似文献
11.
12.
The aim of the present study was to evaluate possible injury provoked by an intensive reproductive programme based on rectal palpation in the cow. Alterations to the mesothelial surface of the peritoneum and to the oviductal mucosa were explored by scanning electron microscopy (SEM). Nine multiparous Friesian cows were selected from each of two commercial dairy herds. Cows in herd 1 were maintained on a weekly reproductive health programme, while those in herd 2 were not subjected to gynaecological exploration. Surface features of the mesothelial cells of the reproductive tract and adjacent ligaments, and the oviductal mucosa were explored by SEM observation of tissue specimens from each animal. Six cows in the intensive reproductive programme showed microscopic alterations of the peritoneal surface. Strands were observed in the oviducts and adjacent ligaments in five of these cows. These strands, composed of filaments covered with mesothelial cells, were probably adhesions. Cells with abundant vacuoles on their surface were detected in the mesothelium corresponding to three animals, two of which also showed microscopic strands. No peritoneal surface alterations were observed in the cows from herd 2. No oviductal mucosal modifications were detected in either group. These findings suggest that intensive reproductive programmes based on rectal palpation may increase the risk of peritoneal surface alterations in the cow, but effects on reproductive physiology are unlikely. 相似文献
13.
An ultrastructural study of malignant mesotheliomas in two cows 总被引：1，自引：0，他引：1
N Hashimoto T Oda K Kadota 《Nippon juigaku zasshi. The Japanese journal of veterinary science》1989,51(2):327-336
Malignant mesotheliomas of two Holstein cows were examined by light and electron microscopy. These tumours were derived from peritoneal surfaces and were of biphasic type composed of mesothelial lining cells and submesothelial mesenchymal cells. Ultrastructurally, the neoplastic mesothelial cells were characterized by intermediate filaments, microvilli, desmosomes, tight junctions and basal laminae. The neoplastic submesothelial cells were closely associated with collagen filaments and some cells had several resemblance to the neoplastic mesothelial cells. The ultrastructural features of the mesotheliomas are discussed in comparison with those of adenocarcinomas and fibroblastic neoplasms. In one case of malignant granulosa cell tumour involved the left ovary and its morphology was apparently different from that of the mesothelioma. Multiple primary tumours are uncommon in cattle. 相似文献
14.
E. Bollo M. Tursi G. Degiorgi S. Capella D. Bellis 《Research in veterinary science》2011,91(1):116-118
An 18-year-old female lion (Panthera leo) was referred to the Department of Animal Pathology of the University of Turin (Italy). At necropsy, multiple nodular, 4-20-mm, confluent white firm nodules were scattered throughout the pleural surfaces of the thoracic wall and of the lungs. Histological lesions were represented by proliferations of papillary structures lined by cuboidal basophilic mesothelial cells with large, oval nuclei and abundant granular eosinophilic cytoplasm. Immunohistochemistry revealed immunoreactivity for pancytokeratin and vimentin. None of the cells expressed calretinin antigen. Asbestos fibers and asbestos bodies were not detected respectively by light microscopy and by Scanning Electron Microscope-Energy Dispersive Spectrometer investigations. On the contrary, chrysotile asbestos were identified in samples from shelter material. Histological and immunohistochemical findings were consistent with the diagnosis of an epithelial malignant mesothelioma. To our best knowledge, this is the first report of a pleural mesothelioma in a lion. 相似文献
15.
利用ELISA试剂盒,对百日鸡的禽白血病抗体和抗原进行了检测。在5个百日鸡父母代鸡群中,1个鸡群的ALV-J抗体阳性率为57.14%,其余鸡群皆为阴性;所有鸡群的ALV-A、B抗体均为阴性;ALV p27抗原除1个鸡群为阴性外,其余鸡群阳性率都较高。在百日鸡的J亚群禽白血病病例中,肝脏、脾脏和肾脏显著肿大,且有弥漫性分布的肿瘤结节;在其他脏器也呈现肿瘤结节。组织病理学观察,发现其脏器等组织中,有一定比例的胞质含红色嗜酸性颗粒的髓细胞样瘤细胞与成淋巴细胞,排列致密呈局灶性生长,正常的组织细胞被挤压或破坏。超微病理观察,在脾脏和法氏囊等组织中均看到病毒颗粒,有囊膜,直径约100nm。部分淋巴细胞核膜、细胞膜水肿或溶解破裂,线粒体和内质网也水肿或池变大、细胞质中出现很多空泡状结构。肿瘤细胞的增多以及细胞内和细胞间的水肿,可能是各脏器严重肿大的主要原因。 相似文献
16.
Pleural space masses and nodules are rarely described on computed tomography (CT) in veterinary medicine and have only been described in patients with neoplasia. Our purpose was to describe the CT findings and diagnoses in seven patients with pleural masses and nodules. Two patients had broad-based, plaque-like pleural masses, both of which were due to neoplasia (primary pleural carcinoma, metastatic thymoma). Two patients had well-defined pleural nodules and nodular pleural thickening, one of which had mesothelial hypertrophy, and another of which had metastatic hemangiosarcoma. Three patients had ill-defined pleural nodules to nodular pleural thickening, one of which had metastatic pulmonary carcinoma, while the other two had bacterial infection with mesothelial proliferation (n = 2), fibrinous pleuritis (n = 1), and severe mediastinal pleuritis/mediastinitis (n = 2). Five of the seven patients had focal, multifocal or diffuse smooth, and/or irregular pleural thickening. Five of seven patients had pleural effusion, and postcontrast CT was useful in several patients for delineating the pleural lesions from the effusion. All patients except one had additional lesions identified on CT besides those in the pleural space. CT is useful in identifying and characterizing pleural space lesions and could be used to guide further diagnostic procedures such as thoracoscopy or exploratory thoracotomy. Both neoplastic and nonneoplastic diseases should be considered in the differential diagnoses for pleural space masses and nodules found on CT. 相似文献
17.
Nodular hyperplasia in the liver of the dog: an association with changes in the Ito cell population 总被引：1，自引：0，他引：1
J R Bergman 《Veterinary pathology》1985,22(5):427-438
The prevalence and morphological features of hyperplastic nodules in the liver of the dog were studied in a series of 50 consecutive post-mortem examinations. Macroscopically visible nodules were present in 35 of 50 dogs (70%), and the prevalence was related to age. The earliest age at which nodules were found was between 6 and 8 years. They were present in all dogs older than 14 or more years. The lesions were focal, multiple and consistently had evidence of a lobular pattern. There was no liver fibrosis. No direct association between previous drug administration or specific extrahepatic disease was found. Changes in the perisinusoidal fat storing cells (Ito cells) were observed in the dogs in this study. These changes comprised proliferation and hypertrophy and were recorded predominantly in dogs with hepatic nodules. The presence of a ceroid pigment was correlated with these changes. The pigment, together with lipid and macrophages, was present in the form of lipogranulomata. Lipogranulomata were observed in the parenchyma and in the portal areas of dogs with hepatic nodules. These changes may play a role in the pathogenesis of nodular hyperplasia in the liver of the dog. 相似文献
18.
Naoaki Yamada Satomi Hashimoto Yuki Tomonari Hiroko Kokoshima Takuya Doi Junko Sato Yumi Wako Minoru Tsuchitani 《Journal of toxicologic pathology》2013,26(3):313-317
A five-month-old male beagle dog suddenly became moribund. Bloody fluid accumulated in the thoracic and abdominal cavities, and soft yellow flecks were floating in the thoracic fluid. The mediastinum and pericardium became dark reddish with villous thickening. Other parietal and pulmonary pleurae were rough, and the organs adhered to each other. Histologically, most mediastinal pleura formed papillary projections covered by a single layer of mesothelial cells. Many macrophages and neutrophils infiltrated the submesothelial connective tissue. At the mediastinum adjacent to the pericardium, cuboidal mesothelial cells proliferated solidly and formed a thick surface stratum. The flecks consisted of gram-negative filamentous or small bacillary (coccoid) bacteria. In the right posterior lobe of the lung, neutrophilic infiltration and a large encapsulated abscess including a bacterial colony were present. We diagnosed this case as “bacterial pleuritis with thickened mesothelial hyperplasia”. The cause of the pleuritis might be a chronic pleural infection spread via the lung abscess. 相似文献
19.
Fun-In Wang Chih-Hua Chang Chen-Hsuan Liu Chian-Ren Jeng 《Journal of veterinary diagnostic investigation》2005,17(1):86-89
A 12-year-old female American badger was presented to the Taipei city zoo veterinary ward with anorexia and weakness. Treatments were ineffective, and the badger died of chronic interstitial nephritis and uremia. At necropsy, numerous firm white nodules, measuring 0.5-2.0 cm, were present on the surface of the liver, stomach, spleen, small intestine, pancreas, and diaphragm. Most nodules were encapsulated and well demarcated from the organs to which they were attached. A poorly demarcated mass, measuring 0.5 cm in diameter, had invaded the hepatic parenchyma and appeared to be the origin of all the nodules derived by transcavitary implantation. Histologically, the nodules contained primarily oval or spindle-shaped cells, typical of smooth muscle cells, forming alternating bundles attached to the surface of the various organs. In some nodules, aggregates of individual polyhedral to round cells with round to oval centrally located nuclei and abundant eosinophilic cytoplasm, typical of smooth muscle origin, were noted. Zones of subcapsular necrosis and multifocal necrosis were also observed in some nodules. Tumor cells stained positively for alpha-smooth muscle actin and vimentin and negatively for desmin, cytokeratin, estrogen, and progesterone receptors. This tumor is similar to but distinguishable from the "disseminated peritoneal leiomyomatosis (DPL)" found in women. 相似文献
20.