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1.
为了探究常山、槟榔和甘草3味中草药制成的复方制剂预防柔嫩艾美耳球虫感染鸡的效果,试验通过建立鸡柔嫩艾美耳球虫感染模型,将复方制剂按0.25 g/kg、0.5 g/kg、1 g/kg和2 g/kg 4个剂量组对感染鸡只进行饲喂。通过存活率、相对增重率、盲肠病变、卵囊值以及抗球虫指数等指标来评价复方制剂预防鸡感染柔嫩艾美耳球虫的效果。试验结果显示,复方制剂中高剂量组的效果为161,抗球虫药效达到中等,复方制剂低剂量组、中剂量组和高剂量组的药效分别为149、152和153,均达到了抗球虫的标准。  相似文献   

2.
复方地克珠利可溶性粉剂抗鸡球虫病效果试验   总被引:2,自引:0,他引:2  
分别以0.5、1.0和1.5mg/L复方地克珠利可溶性粉(以地克珠利有效成分计)饮水,预防鸡柔嫩艾美耳球虫人工感染。并用地克珠利可溶性粉(1.0mg/L)饮水、地克珠利(1.0mg/kg)混饲和硫酸新霉素(50.0mg/L,以效价计)饮水为对照。结果发现,复方地克珠利可溶性粉3种浓度饮水均能有效预防鸡柔嫩艾美耳球虫人工感染,抗球虫指数均在176.46以上,优于地克珠利混饲给药组。  相似文献   

3.
为筛选有效的抗鸽球虫药物,选用地克珠利(1 mg/kg)、磺胺喹恶啉钠(300 mg/kg)、磺胺氯吡嗪钠(300 mg/kg)、托曲珠利(25 mg/kg)、白头翁散(500 mg/kg)等5种抗鸡球虫药物进行了本试验,试验重复3次,每次分为用药感染组和不用药感染组,人工感染主要含有拉氏艾美耳球虫和鸽艾美耳球虫的混合孢子化卵囊,剂量为15×104个,以相对卵囊减少率作为抗球虫效果的指标。结果显示磺胺喹恶啉钠、磺胺氯吡嗪钠效果最好,相对卵囊减少率分别为99.9%和99.5%;其次是托曲珠利、白头翁散,相对卵囊减少率分别为96.7%和92.0%;地克珠利效果最差,相对卵囊减少率仅为75.6%。  相似文献   

4.
亚麻油日粮对地克珠利抗球虫效力的影响   总被引:1,自引:0,他引:1  
研究采取单因子试验设计法。人工感染柔嫩艾美耳球虫6×104/鸡,分别在4%亚麻油日粮中添加0mg/kg、0.6mg/kg和0.8mg/kg抗球虫新药地克珠利,以抗球虫新药地克珠利的推荐量1mg/kg为对照。结果获得:在日粮中添加4%亚麻油后,可减少地克珠利的使用量。抗球虫指数对照组为190,4%亚麻油+0.6mg/kg组为199,4%亚麻油+0.8mg/kg为197。亚麻油对地克珠利抗球虫效力有增效作用。  相似文献   

5.
固体分散型地克珠丽抗鸡柔嫩艾美耳球虫的效果   总被引:2,自引:0,他引:2  
为研究固体分散新剂型地克珠丽对鸡柔嫩艾美耳球虫的防治效果,试验选用120只艾维茵肉仔鸡,试验分4个组,空白对照组、感染不治疗组、添加地克珠丽简单预混剂组和添加固体分散型地克珠丽组。试验结果表明,2种剂型地克珠丽均有抗鸡柔嫩艾美耳球虫的效果,但固体分散型地克珠丽作用效果明显优于简单预混剂地克珠丽。  相似文献   

6.
研究旨在探明两种复合植物提取物对鸡感染柔嫩艾美耳球虫病的防治效果。试验选用21日龄无球虫雏鸡100只,随机分为5组,每组20只。试验分组为:A组(空白对照组)、B组(阳性对照组)(感染球虫不添加抗球虫药物)、C组(地克珠利组)、D组(复合植物提取物Ⅰ试验组)、E组(复合植物提取物Ⅱ试验组)。除空白对照组外,其余每组分别经口感染柔嫩艾美耳球虫孢子化卵囊5×104个/只,感染后当天,A、B组饲喂不含抗球虫药物的基础日粮,C、D、E组饲喂含有相应药物的日粮。结果显示,药物处理组C、D、E组的相对增重率分别为:99.91%、101.9%、74.10%;ACI值分别为196.91、191.90、149.10。由此得出结论:复合植物提取物Ⅰ抗柔嫩艾美耳球虫与地克珠利相比,疗效表现为优秀,且在饲料中添加复合植物提取物Ⅰ的增重效果优于地克珠利,是替代抗球虫、促生长抗生素的良好药物选择。  相似文献   

7.
以1日龄健康雏鸡为试验动物,研究了中药"克球散"、地克珠利、磺胺六甲氧嘧啶及其相互配合用药对鸡柔嫩艾美尔球虫疗效。试验共设9个组,12日龄时在饲料中按要求在相应试验组中加入药物,15日龄时,球虫感染组经口接种柔嫩艾美尔球虫孢子化卵囊8×104个/羽,23日龄剖杀试验鸡,测定抗球虫指数。结果显示:磺胺六甲氧嘧啶组、克球散+磺胺六甲氧嘧啶组、克球散+磺胺六甲氧嘧啶+地克珠利组的抗球虫指数分别为200.10、207.88和196.00,抗球虫效果优秀;磺胺六甲氧嘧啶+地克珠利组、克球散组、克球散+地克珠利组的抗球虫指数分别为169.46、169.14和175.16,抗球虫效果良好;地克珠利组的抗球虫指数为148.91,抗球虫效果相对较差。可见,中西配合用药能够提高疗效。  相似文献   

8.
为探讨发酵复方中草药对鸡球虫病的防治效果,将270只肉鸡分成9组,分别为不感染不给药组、感染不给药组、西药组、复方中草药组以及0.2%、0.5%、1%、2%、3%发酵复方中草药组。依据抗球虫指数对酵母发酵复方中草药治疗鸡柔嫩艾美耳球虫病的效果进行评价。结果表明,西药地克珠利组相对增重率为64%,抗球虫指数为128.3,而2%发酵复方中草药组的相对增重率为85%,抗球虫指数为146.0,在9个试验组中抗球虫效果最好,优于西药组。  相似文献   

9.
将 60只 1日龄蛋公鸡于无球虫条件下饲养至 30日龄时随机分为 5组 (Ⅰ、Ⅱ、Ⅲ、Ⅳ、Ⅴ组 )。Ⅰ组用地克珠利饮水 (每千克水 1mg) ;Ⅱ组地克珠利混饲 (每千克饲料 2mg) ;Ⅲ组为药物对照组 (每千克饲料克球粉 5mg) ;Ⅳ组为感染不给药 ;Ⅴ组为不感染不给药组。于给药当天 ,除Ⅴ组外 ,其他组鸡每只接种 1× 1 0 5个柔嫩艾美耳球虫凤阳地理株孢子化卵囊。根据各组鸡的存活率 ,相对增重率 ,病变记分 ,血便记分和抗球虫指数来观察药物疗效。试验结果表明 ,地克珠利能有效的控制凤阳地理株柔嫩艾美耳球虫。  相似文献   

10.
不同地理株柔嫩艾美耳球虫对地克珠利敏感性试验   总被引:2,自引:0,他引:2  
进行了3个不同地理株的柔嫩艾美耳球虫(吉林株、山东株、黑龙江株)对地克珠利饮水剂的敏感性试验.分别给予试验组鸡1×105个孢子化柔嫩艾美耳球虫卵囊,感染后饮水给予地克珠利药物治疗.结果表明,3株球虫的敏感性不同,其敏感顺序为:山东株>黑龙江株>吉林株.由此可见,柔嫩艾美耳球虫不同地理株间存在对地克珠利的敏感性差异.  相似文献   

11.
12.
Pharmacokinetics and milk levels of ceftriaxone were studied in healthy and endometritic cows following single intravenous administration. The drug was detected up to 8 h of dosing in plasma of healthy and endometritic cows and the drug disposition followed three-compartment open model. The values of Vdarea, AUC, t1/2β, ClB, MRT and P/C ratio were 0.50 ± 0.19 L.kg−1, 62.2 ± 23.3 μg.ml−1.h, 1.02 ± 0.07 h, 0.30 ± 0.09 L.kg−1.h−1, 1.55 ± 0.25 h and 0.52 ± 0.27, respectively, in healthy and 1.55 ± 0.52 L.kg−1, 37.0 ± 17.1 μg.ml−1.h, 1.56 ± 0.25 h, 0.56 ± 0.14 L.kg−1.h−1, 2.14 ± 0.34 h and 1.44 ± 0.60, respectively, in endometritic cows. The drug was detected in milk for 36 h after administration. For MIC90 of 0.5 μg.ml−1 the most appropriate dosage for ceftriaxone, would be 9.0 mg.kg−1 repeated at 6 h intervals for the treatment of endometritis in cows.  相似文献   

13.
This study aimed to evaluate the exogenous progesterone (P4) effect on the luteal function from Day 16 to Day 21 of the oestrous cycle in inseminated goats with unknown pregnancy status. A total of 54 does passed through a short progestin-based synchronization protocol and, on Day 16 of the following oestrous cycle, 27 does received a new P4 device which was retained until Day 21. Blood samples were collected daily from all does during this period, as well as on Day 24. Pregnancy diagnoses were performed on Day 30. Serum P4 values from 26 animals (GNPSP: Group of non-pregnant does with second sponge: n = 8; GNPNSP: Group of non-pregnant does without second sponge: n = 6; GPSP: Group of pregnant does with second sponge: n = 5; GPNSP: Group of pregnant does without second sponge: n = 7) were determined by radioimmunoassay commercial kits. No P4 differences were found between groups (GNPSP: 3.1 ± 2.8; 1.7 ± 1.8; 0.4 ± 1.0; and 0.0 ± 0.0 vs. GNPNSP: 4.4 ± 1.8; 3.0 ± 2.2; 0.8 ± 0.8; and 0.0 ± 0.0 or GPSP: 4.2 ± 1.0; 3.4 ± 0.6; 3.3 ± 1.6; 3.2 ± 0.9; 3.6 ± 1.2; 3.5 ± 1.3; 2.7 ± 1.3 vs. GPNSP: 4.4 ± 1.6; 3.6 ± 1.5; 3.7 ± 1.5; 3.8 ± 1.4; 3.2 ± 1.2; 3.1 ± 1.2; 3.6 ± 1.1; D16, D17, D18, D19, D20, D21, D24, respectively) or for the interaction of group and time. In conclusion, a second progestogen device had no effect on luteolysis or early pregnancy in the following oestrous cycle.  相似文献   

14.
Seventy crossbred ewe lambs, born from Pelibuey (PB) dams mated with five sire breeds: White Dorper × PB (WD × PB), Black Head Dorper × PB (BHD × PB), Ile de France × PB (Ile × PB) Katahdin × PB (KT × PB) and Pelibuey (PB × PB), were used to determine age and weight to puberty, follicular populations during prepubertal development, ovulation rate at first ovulation and function of the first corpus luteum (FCL). Ewe lambs were maintained under grazing conditions and were supplemented with 300 g head− 1 day− 1 of a concentrate with 14% CP and 3.0 Mcal ME kg− 1 of DM. From 145 days of age, monthly observations were performed by endoscopy to monitor follicular populations and luteal structures. Ovarian follicles were classified according to size into small (≥ 1 and < 3 mm), medium (≥ 3 and ≤ 4 mm) and large (> 4 mm). Additionally, weekly observations by ultrasonography were performed in four ewes per genotype to assess follicular populations. Luteal function from first ovulation was determined by circulating concentrations of progesterone. Ovulation rate was not affected by genotype (P > 0.05). All breed groups had the same pattern of follicular populations, where most of follicles were small, followed by medium and a small proportion of large follicles. Maximum diameter of follicles was similar for all genotypes during prepubertal development (P > 0.05), with an average range of 3.9 ± 0.20 to 4.4 ± 0.20 mm. The BHD × PB reached puberty at the youngest age of 240.9 ± 13.0 days, compared to all other genotypes (P < 0.05), 259.1 ± 11.7 for WD × PB, 279.3 ± 9.6 for KT × PB and 289.0 ± 15.3 days for PB × PB and 308.6 ± 11.9 days for Ile × PB ewe lambs. Ile × PB had greater weight to first ovulation (31.5 ± 1.19 kg) as compared to other breed groups (P < 0.01). The largest percentage of FCL was for KT × PB ewes (100%) (P < 0.05), followed by BHD × PB (88.9%), PB × PB (83.3), WD × PB (78.6%) and Ile × PB (77.8%). There were no differences in ovulation rate attributable to type of lambing from which ewe lambs came from (P > 0.05). BHD × PB ewe lambs reached puberty at an earlier age than other in this study. KT × PB ewe lambs had the highest percentage of FCL in their first ovulation. Breed of sire Ile de France increased weight to puberty and decreased FCL at first ovulation. In conclusion, the BHD × PB ewe showed puberty at an earlier age than other genotypes, while the KT × PB had the highest percentage of functional corpus luteum in their first ovulation. Ewe lambs coming from single lambings reach puberty at a heavier weight than those coming from multiple lambings. The ovulation rate in the first ovulation of ewe lambs is not affected by genotype and type of lambing.  相似文献   

15.
Four growing pigs (initial liveweight 25.9 ± 0.54 kg, final liveweight 43.0 ± 1.06 kg) were used to study the effect of dietary lysine level on nutrient digestibility, whole-body protein turnover, plasma insulin-like growth factor-I (IGF-I), growth hormone (GH), insulin, glucose, and urea nitrogen (PUN). Four diets, containing 7.0 g (L1), 9.5 g (L2), 12.0 g (L3) and 14.5 g (L4) lysine per kg diet respectively, were formulated as experimental treatments. The animals and diets were allocated in a 4 × 4 Latin square design. Nitrogen (N) metabolism and whole-body protein turnover were measured by classical method and single-dose 15N end-product method, respectively. The blood samples were taken at the end of each experimental period. Results showed that N retention (NR) and N biological value (NBV) were significantly increased from L1 to L4 (P < 0.05). However, differences in NR and NBV between L2, L3 and L4 were not significant (P > 0.05). There was no significant difference on dry matter (DM) digestibility, organic matter (OM) digestibility and N digestibility between different treatments (P > 0.05). Whole-body protein synthesis, protein degradation and protein accretion increased markedly from L1 to L2 (P < 0.05), but did not increase further from L2 to L4. Whole-body protein accretion (y, g/kg W0.75/d) increased with dietary lysine (x, g/kg) in a quadratic manner: y = − 0.09x2 + 2.12x − 5.14 (r2 = 0.96, n = 4, P < 0.05).The results also showed that differences in plasma IGF-I, GH, glucose and PUN concentration between different treatments were not significant (P > 0.05). Plasma insulin concentration (y, μIU/ml) was increased with dietary lysine (x, g/kg) in a quadratic manner: y = 0.23x2 − 4.10x + 32.25 (r2 = 0.99, n = 4, P < 0.05), but it was not found that plasma insulin concentration was related to NR. A significant correlation was found between NR (y, g/d) and plasma IGF-I (x, ng/ml): y = − 3.1 × 10− 3x2 + 1.31x − 122.28 (r2 = 0.99, n = 4, P < 0.05).It was concluded that dietary lysine level had a significant influence on NR and whole-body protein turnover but not on plasma IGF-I and GH concentration. Plasma IGF-I may be an important factor controlling N metabolism of growing pigs. Further research was needed to study the mechanism.  相似文献   

16.
In this study the disposition kinetics and plasma availability of moxifloxacin in Muscovy ducks after single intravenous (i.v.), intramuscular (i.m.) and oral (p.o.) administrations of 5 mg kg?1 b.wt. were investigated. The concentrations of moxifloxacin in the plasma were measured using high-performance liquid chromatography (HPLC) with fluorescence detection on samples collected at frequent intervals after drug administration. Following intravenous injection, the decline in plasma drug concentration was bi-exponential with half-lives of (t1/2α) 0.22 ± 0.10 h and (t1/2β) 2.49 ± 0.26 h for distribution and elimination phases, respectively. The volume of distribution at steady-state (Vdss) was 1.02 ± 0.14 l kg?1 and the total body clearance (Cltot) was 0.32 ± 0.11 l kg?1 h?1, respectively. After intramuscular and oral administration of moxifloxacin at the same dose the peak plasma concentrations (Cmax) were 2.38 ± 0.43 and 2.11 ± 0.36 μg ml?1 and were obtained at 1.47 ± 0.26 and 1.83 ± 0.16 h (Tmax), respectively, the elimination half-lives (T1/2el) were 3.14 ± 0.42 and 2.63 ± 0.44 h, respectively, and AUC0–24 were 15.87 ± 2.35 and 14.52 ± 2.37 μg ml?1 h?1, respectively. The systemic bioavailabilities were 96.36 ± 11.54% and 86.79 ± 12.64%, respectively. In vitro plasma protein binding percent was 32%. We concluded that moxifloxacin might be clinically interesting alternative for the treatment of most sensitive bacterial infections in Muscovy ducks.  相似文献   

17.
Summary Leptospira interrogansserotypes pomonaand icterohaemorrhagiaewere isolated from the kidneys of Rattus norvegicustrapped on pomonainfected piggeries.The isolation of pomonafrom one of 111cultured kidneys, although of interest, strongly suggests that this rat does not play an important part in the epidemiology of infection by this serotype. Kidney tubular degeneration, focal mononuclear infiltrations and fibroplasia are morphological traces which remain after an attack of leptospirosis. The high percentage (48.6)of these lesions found in the rat kidneys examined does not seem to be related to serotype pomonabut to icterohaemorrhagiae.The importance of this last serotype in swine in the Cauca Valley has yet to be assessed.
Leptospirosis En Colombia: Aislamiento DeLeptospira SPP. De Riñones De Ratas Pardas (Rattus Norvegicus) Atrapadas En Porquerizas Infectadas
Resumen Se aislóLeptospira interrogans serotipospomona eicterohaemorrhagiae de riñones deRattus norvegicus atrapadas en porquerizas infectadas porpomona. El aislamiento depomona de 1/111 riñones cultivados, aunque de interés, sugiere que esta rata no desempeña parte importante en la epidemiología de las infecciones por este serotipo.Degeneración tubular renal, infiltración mononuclear focal y fibroplasia son huellas morfológicas que quedan después de un ataque de leptospirosis. El alto porcentaje (48.6) de estas lesiones encontradas en los riñones de las ratas examinadas no parece estar relacionado con el serotipopomona sino con elicterohaemorrhagiae. La importancia de este último seroptipo en cerdos en el Valle del Cauca no se ha evaluado todavía.

Leptospiroses En Colombie: Isolement DeLeptospira SPP. De Reins De Rats Bruns (Rattus Norvegicus) Captures Dans Des Porcheries
Résumé Les sérotypespomona eticterohaemorrhagiae deLeptospira interrogans ont été isolés de reins deRattus norvegicus capturés dans des porcheries infectées de (pomona?). L'isolement depomona sur une seule des 111 cultures de rein effectuées, bien qu'interessant, suggère fortement que ce rat ne joue pas un rôle important dans l'épidémiologie de l'infection par ce sérotype.La dégénerescence tubulaire des reins, des infiltrations ponctuelles par des monocucléaires et l'aspect fibreux constituent les traces morphologiques qui demeurent après une attaque de leptospirose. Le pourcentage élevé (48,6) de ces lésions trouvées dans les les reins des rats examinés semble être plus en rapport avec le sérotypeicterohaemorrhagiae qu'avec le sérotypepomona. L'importance du sérotypeicterohaemorrhagiae chez le porc de la Cauca Valley est encore à vérifier.
  相似文献   

18.
Summary Microfilariae of three genera, namelyElaeophora böhmi, Onchocerca cervicalis andParafilaria multipapillosa were recovered from blood samples of equidae in Tehran, Iran. These microfilarial infections in equidae are reported for the first time from Iran.
Infestacion Filaroidea De Equinos En El Area De Teheran, Iran
Resumen Microfilarias de tres géneros,Elaeophora bohmi, Onchocerca cervicalis andParafilaria multipapillosa se aislaron de la sangre de equinos en el area de Teherán, Irán. Este es el primer reporte de la infestación filaroidea de equinos en Irán.

Filariose Des Equides Dans La Region De Teheran En Iran
Résumé Les microfilaires des genresElaeophora böhmi, Onchocerca cervalis etParafilaria multipapillosa ont été trouvées dans des échantillons de sang d'équidés de la région de Téhéran en Iran. C'est la première fois qu'un tel parasitisme des équidés est constaté en Iran.
  相似文献   

19.
Summary A serological survey of cattle in Mali was carried out to determine the prevalence of antibody activity toBabesia bovis andB. bigemina. It was found that the level ofB. bovis infection as indicated by antibody activities was too low to be of immediate concern. However, the serological prevalence ofB. bigemina was high and this may indicate a potential disease problem. It was also found that when zebu and N'Dama cattle grazed together the N'Dama were twice as likely to have positive titres toBabesia as were the zebus.
Prevalencia Serologica De Babesiosis Bovina En Mali
Resumen Se llevó a cabo un análisis serológico en Malí, para detectar la prevalencia deBabesia bovis yBabesia bigemina. Se encontró, que la prevalencia serológica deB. bovis es baja para considerar la enfermedad una amenaza inmediata. Sinembargo, la prevalencia deB. bigemina fué alta, un problema potencial. Tambien se encontró, que cuando el ganado Cebu y N'Dama pastorea junto, el N'Dama presenta el doble de títulos serológicos deB. bigemina.

Frequence Serologique De La Babesiose Bovine Au Mali
Résumé Une enquête sérologique sur le bétail au Mali a été effectuée pour déterminer la fréquence de l'activité des anticorps àBabesia bovis etB. bigemina. On a trouvé que le degré d'infection àB. bovis tel qu'indiqué par les réactions anticorps était trop faible pour constituer un souci immédiat. Cependant la fréquence sérologique deB. bigemina était élevée, ce qui peut indiquer un problème pathologique potentiel. On a aussi noté que lorsque les zébus et les N'Dama broûtaient ensemble, les N'Dama avaient deux fois plus de chance d'avoir des titres positifs àBabesia que ne l'avaient les zébus.
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Our objective was to determine the effect of forage ensiling and ration fermentation on total mixed ration pH, ruminal fermentation and animal performance. Thirty Holstein‐Zebu cross steers were allotted to feeding treatments for 188 days in a randomized complete block design including: fresh grass‐total mixed ration (GTMR; pH 4.7), grass silage‐TMR (STMR; pH 4.0) and fermented‐TMR (FTMR; pH 3.5). Average daily gain for STMR was greatest during the first 3 months period; however, that for FTMR tended to be greater than GTMR during the second 3 months period (< 0.10). During the second period dry matter intake for STMR was the greatest (< 0.01), but feed conversion ratio (< 0.01) and cost per gain (< 0.01) were the least for FTMR. Protein digestibility tended (< 0.10) to be greater for FTMR than STMR and fat digestibility was greater (< 0.05) for GTMR and FTMR than STMR. FTMR had less (< 0.01) ruminal NH3‐N content than STMR. Total volatile fatty acids post‐feeding was greatest for GTMR (< 0.01). Ruminal proportions of acetic and butyric acids were greater for FTMR than GTMR (< 0.05); in contrast, propionic acid was greater for GTMR (< 0.05). Utilizing silage or total ration fermentation did not negatively impact on ruminal pH. STMR and FTMRs can be used to maintain performance of growing crossbred Holstein steers.  相似文献   

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