Down regulation of hepatic PPARalpha function by AhR ligand   总被引：1，自引：0，他引：1  

Shaban Z  El-Shazly S  Abdelhady S  Fattouh I  Muzandu K  Ishizuka M  Kimura K  Kazusaka A  Fujita S 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2004,66(11):1377-1386

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No alteration in serum leptin levels during acute endotoxemia in sheep.     

M Soliman  S Abdelhady  I Fattouh  K Ishioka  H Kitamura  K Kimura  M Saito 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2001,63(10):1143-1145

To determine the role of leptin in endotoxin-induced anorexia in ruminants, circulating leptin levels were measured during acute experimental endotoxemia in sheep. Injection of bacterial lipopolysaccharide (450 ng/kg, i.v.) induced anorexia accompanied with fever and increases in serum levels of cortisol, insulin and glucose which are known to stimulate leptin secretion in rodent and human, while it did not affect serum leptin levels at all. These results indicate that serum leptin levels in sheep during acute endotoxemia are differentially regulated from those in rodent and human, and that leptin might not be involved in the endotoxin-induced anorexia in sheep.  相似文献   

The first detection of anti-West Nile virus antibody in domestic ruminants in Egypt     

Selim  Abdelfattah  Abdelhady  Abdelhamed 《Tropical animal health and production》2020,52(6):3147-3151

West Nile virus (WNV) is a mosquito-borne disease, usually present as a symptomatic disease but can cause various clinical signs ranged from mild fever to severe encephalitis and death in various animals and humans. In Egypt, the epidemiological data about WNV infection in different animal species particularly in domestic ruminants are scarce. The present study aimed to investigate the seroprevalence of WNV in cattle, buffalo, camel, sheep, and goats at some Governorates northern Egypt. In total, 360 serum samples (100 cattle, 50 buffalo, 50 camels, 85 sheep, and 75 goats) were examined using ELISA. The results revealed that the seroprevalence of WNV among ruminants was highly significant (P = 0.03) at Kafr El Sheikh Governorate (17.6%) in comparison with other the Governorates. Besides, the seroprevalence of WNV antibodies significantly differed between the examined species (P = 0.0001); it was 22%, 0%, 40%, 3.5%, and 5.3% in cattle, buffalo, camel, sheep, and goats, respectively. This is the first study to confirm that domestic ruminants act as a reservoir in the epidemiology of WNV infection and represent a risk for human and equine infections in Egypt.

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