Prognosis for dogs with appendicular osteosarcoma treated by amputation alone: 162 cases (1978-1988).   总被引：3，自引：0，他引：3  

G J Spodnick  J Berg  W M Rand  S H Schelling  G Couto  H J Harvey  R A Henderson  G MacEwen  N Mauldin  D L McCaw 《Journal of the American Veterinary Medical Association》1992,200(7):995-999

Long-term follow-up information pertaining to 162 dogs with appendicular osteosarcoma treated by amputation alone was collected from 17 veterinary institutions. The majority (72.5%) of dogs died or were euthanatized because of problems documented to be related to metastases. The first clinically apparent sites of metastasis were the lungs (60.8% of total), the skeleton (5.2%), or both (4.6%). A Kaplan-Meier survivorship distribution was plotted on the basis of available survival time data in all 162 dogs. The mean and median survival times were estimated to be 19.8 and 19.2 weeks, respectively, and the 1- and 2-year survival rates were estimated to be 11.5 and 2.0% respectively. Statistically significant relationships were not found between survival time and reporting institution, gender, site of primary tumor, whether the primary tumor was proximally or distally located, whether the primary tumor was located in the forelimb or hind limb, whether presurgical biopsy was performed, and whether death was tumor related. A significant (P less than 0.01) quadratic relationship was found between age and survival time. Survival time was longest in dogs 7 to 10 years old and was shorter in older and younger dogs.  相似文献   

In vitro immunologic features of Weimaraner dogs with neutrophil abnormalities and recurrent infections     

C G Couto  S Krakowka  G Johnson  P Ciekot  R Hill  L Lafrado  G Kociba 《Veterinary immunology and immunopathology》1989,23(1-2):103-112

In vitro evaluation of cellular and humoral immunity in Weimaraner dogs with recurrent infections and abnormal neutrophil function revealed significantly lower serum immunoglobulin (Ig) G and M concentrations than control dogs. Lymphocyte blastogenesis in response to three different mitogens, interleukin-1 and -2 production, natural killer (NK) cell activity, and in vitro IgG and IgM production were similar to those of control dogs.  相似文献   

Segmental ischaemic necrosis of the jejunum in a post-partum mare due to two mesenteric avulsions     

L. Vilaregut  C. O'Shea  M. Lores  G. Couto  M. Misheff 《Equine Veterinary Education》2020,32(8):e106-e110

This report describes segmental ischaemic necrosis of the small intestine 4 days after foaling in a 9-year-old Arabian mare. The jejunal mesentery was avulsed from the intestine in two locations for 20 and 200 cm, resulting in intestinal necrosis, in the absence of entrapment or strangulation. This case highlights the need to consider the possibility of mesenteric injury when a post-partum mare presents mild signs of abdominal pain.  相似文献   

Sand fractions micromorphometry detected by Vis-NIR-MIR and its impact on water retention     

Luis Augusto Di Loreto Di Raimo  Eduardo Guimarães Couto  José Alexandre Mello Demattê  Ricardo Santos Silva Amorim  Gilmar Nunes Torres  Cassiano Cremon  Danilo César de Mello  Edwaldo Dias Bocuti  Raul Roberto Poppiel  Adeilson Nascimento da Silva  Lucas Nunes Lima  Luis Carlos Gomes Neto 《European Journal of Soil Science》2022,73(2):e13227

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White-coat effect on systemic blood pressure in retired racing Greyhounds     

Marino CL  Cober RE  Iazbik MC  Couto CG 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2011,25(4):861-865

Background: Greyhounds are known to have a higher systemic arterial blood pressure (BP) than non‐Greyhound dogs. Objectives: The purpose of this study was to determine whether the high systemic BP was because of the white‐coat effect. Animals: Twenty‐two healthy retired racing Greyhounds (RRG) enrolled in a blood donation program. Materials/Methods: We prospectively measured systemic BP in 3 environments: in the hospital by the investigator (Hosp), in the home by the investigator (H/I), and in the home by the owner (H/O). Five serial measurements of systolic, diastolic, and mean arterial pressures (SAP, DAP, MAP) as well as heart rate (HR) were measured by an oscillometric method on the distal forelimb and distal hind limb in all 3 environments. Results: There was a significant difference for SAP, MAP, and HR between the Hosp and both H/I and H/O (P < .001); there were no significant differences for any of the parameters between the H/I and H/O environments. HR, but not SAP, MAP, or DAP (P < .05) decreased in RRG with multiple hospital visits for blood donation before this study. The hind limb SAP was significantly higher than the forelimb SAP (P < .05). Conclusions and Clinical Importance: We conclude that the high SAP, MAP, and HR seen in the hospital setting are likely because of a white‐coat effect. Furthermore, consideration should be given to defining the parameters of normal BP in RRG according to the environment in which they are obtained.  相似文献   

Seasonal dynamics of cyathostomin (Nematoda - Cyathostominae) infective larvae in Brachiaria humidicola grass in tropical southeast Brazil     

dos Santos CN  de Souza LS  Quinelato SB  do Couto MC  Pinheiro J  Rodrigues ML 《Veterinary parasitology》2011,180(3-4):274-278

The ecology of cyathostomin larvae was evaluated in different seasons, from July 2007 to June 2008, in the municipality of Seropédica, Rio de Janeiro state, southeastern Brazil. Samples of feces and grass were collected every 15 days at 8 AM and 5 PM and the infective larvae were recovered by the Baermann technique. Leaves of the grass Brachiaria humidicola were cut to 20 cm, which is the length containing most of the larvae. The highest number of larvae was recorded at 8 AM the winter (8300 L(3)kg(-1)dm) and spring (5300 L(3)kg(-1)dm). These results demonstrate that climate conditions can affect the recovery of larvae and that rain and temperature contributed to the migration and survival of the larvae, which were available throughout the year in the study area.  相似文献   

Thromboelastography in healthy, sick non-septic and septic neonatal foals     

Mendez-Angulo JL  Mudge M  Zaldivar-Lopez S  Vilar-Saavedra P  Couto G 《Australian veterinary journal》2011,89(12):500-505

Objectives To evaluate citrated recalcified thromboelastography (TEG) in healthy newborn foals, and to determine intra‐assay, inter‐individual and intra‐individual (at 12 h, 24 h and 7 days after birth) variations. Additionally, to compare TEG variables, haematological values and conventional coagulation profiles from healthy, sick non‐septic, and septic foals. Design Prospective study. Methods The study group comprised 18 healthy, 15 sick non‐septic and 17 septic foals. Two citrated (3.2%; 1 : 9 anticoagulant : blood ratio) blood samples were submitted for haemostatic evaluation using a TEG analyser and conventional coagulation profile. TEG values (R time (R), K time (K), angle (α), maximum amplitude (MA) and G value (G)), complete blood count (CBC) and conventional coagulation profile (prothrombin time (PT), activated partial thromboplastin time (aPTT), fibrinogen concentration (Fib) and antithrombin (AT)) were evaluated. Signalment, presenting complaint, sepsis scores, blood culture results and outcome were taken from the medical records of the sick foals. Results Mean values ± SD for TEG variables in healthy neonatal foals were: R = 11.82 ± 5.35 min, K = 3.06 ± 1.34 min, α= 51.19 ± 12.66 degrees, MA = 55.06 ± 6.67 mm and G = 6361 ± 1700 dyn/cm². Mean coefficients of variation for intra‐assay/inter‐individual/intra‐individual in healthy foals were: R = 3.5/45.2/43.1%; K = 5.3/58.7/28.7%; α= 1.5/24.7/11.9%; MA = 0.3/12.1/6.1%; G = 1.6/26.7/14.7%. Septic foals had significantly greater α, MA and G values than sick non‐septic foals, and significantly greater MA and G than healthy foals, changes that are consistent with hypercoagulability. Weak correlations were detected between TEG variables and haematological or haemostatic values. Conclusions TEG could be used to provide additional information about the haemostatic system in equine neonates.  相似文献   

Genetic variation and variation in aggressiveness to native and exotic hosts among Brazilian populations of Ceratocystis fimbriata     

Harrington TC  Thorpe DJ  Alfenas AC 《Phytopathology》2011,101(5):555-566

Ceratocystis fimbriata is a complex of many species that cause wilt and cankers on woody plants and rot of storage roots or corms of many economically important crops worldwide. In Brazil, C. fimbriata infects different cultivated crop plants that are not native to Brazil, including Gmelina arborea, Eucalyptus spp., Mangifera indica (mango), Ficus carica (fig), and Colocasia esculenta (inhame). Phylogenetic analyses and inoculation studies were performed to test the hypothesis that there are host-specialized lineages of C. fimbriata in Brazil. The internal transcribed spacer region ribosomal DNA sequences varied greatly but there was little resolution of lineages based on these sequences. A portion of the MAT1-2 mating type gene showed less variation, and this variation corresponded more closely with host of origin. However, mango isolates were found scattered throughout the tree. Inoculation experiments on the five exotic hosts showed substantial variation in aggressiveness within and among pathogen populations. Native hosts from the same families as the exotic hosts tended to be less susceptible than the cultivated hosts, but there was little correlation between aggressiveness to the cultivated and native hosts of the same family. Cultivation and vegetative propagation of exotic crops may select for strains that are particularly aggressive on those crops.  相似文献   

Movement of genotypes of Ceratocystis fimbriata within and among Eucalyptus plantations in Brazil     

Ferreira MA  Harrington TC  Alfenas AC  Mizubuti ES 《Phytopathology》2011,101(8):1005-1012

Ceratocystis wilt on eucalyptus, caused by Ceratocystis fimbriata, was first recognized in 1997 in the state of Bahia, Brazil, but is now known in five other states and in four other countries. C. fimbriata is a native, soilborne pathogen in some parts of Brazil but we hypothesized that genotypes of the pathogen have been moved among plantations in rooted cuttings collected from diseased trees and within plantations on cutting tools. We used six microsatellite markers to identify 78 genotypes of C. fimbriata among 177 isolates from individual trees in 20 eucalyptus plantations. The highest gene and genotypic diversity values were found in plantations on formerly wild Cerrado forest in Minas Gerais, suggesting that the fungus was in the soil prior to planting eucalyptus. In contrast, one or only a few genotypes were found in plantations on previous pastureland (with no woody hosts) in Bahia and S?o Paulo, and most of these genotypes were found in a Bahian nursery or in one of two Bahian plantations that were sources for rooted cuttings. Sources of cuttings tended to be dominated by one or a few genotypes that may have been spread within the plantation on cutting tools.  相似文献   

Glyphosate reduces urediniospore development and Puccinia psidii disease severity on Eucalyptus grandis     

Santos LD  Graça RN  Alfenas AC  Ferreira FA  Melo CA  Machado MS 《Pest management science》2011,67(7):876-880

BACKGROUND: Recent studies have shown the effects of glyphosate drift on decreasing rust intensity on Eucalyptus grandis plants. However, the effects of the herbicide on Puccinia psidii initial development are unknown. In this study the systemic action of glyphosate on rust severity was evaluated on Eucalyptus plants maintained under greenhouse conditions. Urediniospore germination and apressorium formation on detached leaves and on water agar medium, previously treated with glyphosate, were also evaluated. RESULTS: Rust severity and the number of urediniospores per leaf area were significantly reduced with increasing glyphosate doses, even on branches not directly treated with the herbicide, indicating a systemic effect of glyphosate on pathogen development. Similarly, higher glyphosate doses also reduced germination and apressorium formation on detached Eucalyptus leaves, regardless of the direct application of the product on the leaf limb or on the petiole base. Puccinia psidii urediniospore germination in water agar medium also decreased with increasing herbicide doses. CONCLUSIONS: Reductions in germination and apressorium formation of P. psidii urediniospores with increasing glyphosate dose indicate that a lower severity and intensity of the disease may perhaps be due to blockage of the shikimic acid pathway in the fungal metabolic system. Copyright © 2011 Society of Chemical Industry  相似文献