Congenital cutaneous, oral, and periarticular hemangiosarcoma in a 9-day-old Rocky Mountain horse     

Dunkel BM  Del Piero E  Kraus BM  Palmer JE  Lin P  Wilkins PA 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2004,18(2):252-255

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Molecular characterisation of a field strain of bubaline herpesvirus isolated from buffaloes (Bubalus bubalis) after pharmacological reactivation     

De Carlo E  Re GN  Letteriello R  Del Vecchio V  Giordanelli MP  Magnino S  Fabbi M  Bazzocchi C  Bandi C  Galiero G 《The Veterinary record》2004,154(6):171-174

Two healthy buffaloes (Bubalus bubalis) in a herd which had not been vaccinated against infectious bovine rhinotracheitis (IBR), were selected for their seropositivity for anti-bovine herpesvirus type 1 (BoHV-1) glycoprotein E antibodies, and injected intramuscularly daily with dexamethasone for five consecutive days (day 1 to day 5) to reactivate any latent herpesvirus. Blood samples and nasal and vaginal swabs were collected daily from day 5 to day 15 from each buffalo for virological examination. All the vaginal swabs and blood samples were negative, but 13 of the 22 nasal swabs were positive; a cytopathic effect was observed in primary cultures of bovine fetal lung cells, and the viral isolates were identified as a herpesvirus by PCR. The viral strains were characterised by the sequence analysis of the genes coding for glycoproteins D and B, and the gene sequences were then used for phylogenetic analysis. The isolates from both buffaloes appeared identical at the level of the two genes, and were more closely related to bovine herpesvirus type 5 than to BoHV-1.  相似文献   

TSL-1 antigens of Trichinella: an overview of their potential role in parasite invasion, survival and serodiagnosis of trichinellosis     

Bolás-Fernandez F  Corral Bezara LD 《Research in veterinary science》2006,81(3):297-303

The majority of studies on the immunobiology of Trichinella species have centred on the larval muscular phase (L1) with a view to identifying immunodominant antigens located on the surface of the cuticle and in the larval secretions; the nucleus of the parasite-host interaction. These antigens have been classified as eight groups (TSL-1-TSL-8), of which those belonging to the group TSL-1 have been most intensely studied. The principal constituents are glycoproteins, glycan carriers that contain a unusual sugar, the tyvelose (3,6-dideoxy-d-arabinohexose). Studies aimed at improving serodiagnostic techniques to detect trichinellosis indicate that these antigens are ideal candidates. They are capable of inducing a strong humoral response involving the generation of specific antibodies against beta-tyvelose, a sugar that seems to be exclusive to the Trichuroidea. Furthermore, these glycoproteins appear to fulfil an important function in the development and maintenance of the parasite in the muscular niche, and they appear to be fundamental for the invasion of the intestinal epithelium. It has also been demonstrated that specific monoclonal antibodies against tyvelose can mediate a degree of immunoprotection in the rat through the phenomenon known as rapid expulsion.  相似文献   

Phenylphenalenone type compounds from the leaf fibers of abaca (Musa textilis)     

Del Río JC  Jiménez-Barbero J  Chavez MI  Politi M  Gutiérrez A 《Journal of agricultural and food chemistry》2006,54(23):8744-8748

A series of phenylphenalenone type compounds, known to play a role as phytoalexins in plants of the Musaceae family, have been identified for the first time in the leaf fibers of abaca (Musa textilis). Among the phenylphenalenone type compounds identified, the structure of a novel compound, (1R)-2,3-dihydro-4,9-dihydroxy-8-methoxy-1-phenylphenalene, has also been described in abaca fibers. Its structure was elucidated by analysis of one- and two-dimensional NMR (correlation spectroscopy, heteronuclear single quantum correlation, and heteronuclear multiple bond correlation) spectroscopic data.  相似文献   

What is your diagnosis? Desmitis of the right accessory ligament of the superficial digital flexor tendon     

Vidal MA  Valdes-Martinez A  Bueno AC 《Journal of the American Veterinary Medical Association》2006,228(6):845-846

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Comparative spatial analysis of the sooty blotch/flyspeck disease complex,bull’s eye and bitter rots of apples     

P. Spolti  R. M. Valdebenito‐Sanhueza  F. F. Laranjeira  E. M. Del Ponte 《Plant pathology》2012,61(2):271-280

The incidence of sooty blotch/flyspeck (SBFS) and bitter and bull’s eye rots were assessed in a Fuji apple orchard during two seasons. Using a regular sampling design, 252 trees were selected and 20 fruits per tree were sampled at harvest and scored for disease incidence. For bitter and bull’s eye rots, additional assessments were made on all symptomless fruit after a 30‐day period of storage. Randomness in the spatial pattern was assessed using beta‐binomial analysis of incidence data for three sampling scales (one, three or six adjacent trees as sampling units) and using Spatial Analysis by Distance Indices (sadie ) for disease counts for the 3‐tree sampling scale. sadie was also used for testing spatial associations between a pair of diseases, between years for the same disease or between rotted and latently infected fruit. Using a toroidal‐shifts procedure, 360 maps of disease counts were created based on the observed data, which were further analysed using sadie . Most datasets showed an aggregated spatial pattern, which was more consistent for the two fruit rots than SBFS, which showed distinct patterns depending on the year or method of analysis. The two fruit rots were spatially associated in most situations but SBFS and bull’s eye rot were dissociated in one season. Results from virtual orchards showed that the patterns observed in the original maps may accurately represent those in similar apple‐growing areas. Hypotheses regarding aspects of ecology and epidemiology of pathogens studied and potential efficacy of control measures in the region are discussed.  相似文献   

Materials science. Order from disorder     

D Wang  A Fernandez-Martinez 《Science (New York, N.Y.)》2012,337(6096):812-813

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Granulomatous giant cell submandibular sialadenitis in a dog     

Alejandro Pérez-écija  José Carlos Estepa  Francisco Javier Mendoza 《The Canadian veterinary journal. La revue veterinaire canadienne》2012,53(11):1211-1213

A 4-month-old dog was presented with a progressive swelling of the submandibular area. The history, course, cytological, and sialographic findings were consistent with an aseptic pyogranulomatous sialadenitis with concurrent duct blockage. This rare entity, responsive to medical treatment, appears to be similar to the granulomatous giant cell sialadenitis of humans.  相似文献   

Interleukin-6 and insulin incrase and nitric oxide and adiponectin decrease in blind dogs with pituitary-dependent hyperadrenocorticism     

Cabrera Blatter MF  Del Prado B  Miceli DD  Gomez N  Ivanic J  Di Tollo B  Gallelli MF  Castillo VA 《Research in veterinary science》2012,93(3):1195-1202

In this study, two populations of dogs with pituitary dependent hypercortisolism (PDH) were compared over a 2-year period. One group had normal vision (Group A, n=27) and one group was blind (Group B, n=20). Group B was characterised by the rapid appearance of the clinical signs of PDH that precede blindness. We found increases in pre-adrenocorticotropic hormone cortisol (P=0.002), IL-6 (P=0.0001), insulin, and insulin sensitivity (detected with the Homeostatic Model Assessment, P<0.0001) in Group B but not in Group A. The nitric oxide (NO) and the total adiponectin concentrations decreased (P=0.0001 and P=0.02, respectively) in Group B versus Group A. The IL-6 and insulin concentrations and the HOMA-A index were positively correlated with the cortisol concentration and were negatively correlated with the NO concentration. With the exception of adiponectin, the other variables were associated with blindness. We concluded that blindness in PDH is a haemodynamic event associated with metabolic changes, with the increase in the IL-6 concentration and the decrease in the NO concentration affecting the retinal vasculature and producing a high risk of vision loss.  相似文献   

Development and characterization of mouse monoclonal antibodies reactive with chicken CD83     

Lee SH  Lillehoj HS  Jang SI  Lee KW  Baldwin C  Tompkins D  Wagner B  Del Cacho E  Lillehoj EP  Hong YH 《Veterinary immunology and immunopathology》2012,145(1-2):527-533

This study was carried out to develop and characterize mouse monoclonal antibodies (mAbs) against chicken CD83 (chCD83), a membrane-bound glycoprotein belonging to the immunoglobulin superfamily that is primarily expressed on mature dendritic cells (DCs). A recombinant chCD83/IgG4 fusion protein containing the extracellular region of chCD83 was expressed in Chinese Hamster Ovary (CHO) cells and isolated from the spent cell culture medium by protein G affinity chromatography. The extracellular region of the chCD83 protein was purified and used to immunize mice. A cell fusion was performed, from which 342 hybridomas were screened for mAbs to chCD83. Two mAbs, chCD83-159 and chCD83-227, stained the greatest percentage of chCD83-transfected CHO cells and were selected for further characterization. By flow cytometry, both mAbs reacted with a chicken macrophage cell line, HD11. Both mAbs also recognized a single 53 kDa protein on Western blots of lysates from lipopolysaccharide-stimulated spleen mononuclear cells or unstimulated HD11 cells. Immunostaining of chicken secondary lymphoid organs identified chCD83(+) cells with morphologic and subtissue localization properties comparable to mammalian DCs. In vitro stimulation of spleen mononuclear cells with concanavalin A (Con A) decreased the percentage of chCD83(+) cells compared with cells treated with medium alone. Interestingly, spleen cells treated with Con A in the presence of chCD83-227 mAb exhibited decreased percentage of MHCII(+) cells compared with cells treated with an isotype-matched negative control mAb. These chCD83 mAbs may be useful for future investigations of chicken immune cell maturation and mechanisms of action.  相似文献