Clinicopathologic features and outcome predictors of Leptospira interrogans Australis serogroup infection in dogs: a retrospective study of 20 cases (2001-2004)     

Mastrorilli C  Dondi F  Agnoli C  Turba ME  Vezzali E  Gentilini F 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2007,21(1):3-10

BACKGROUND AND HYPOTHESIS: We retrospectively evaluated the clinicopathologic findings and outcome predictors in dogs with Leptospira interrogans Australis serogroup infections. ANIMALS AND METHODS: The medical records of 159 dogs that had a leptospiral microscopic agglutination test (MAT) performed between 2001 and 2004 were reviewed. RESULTS: Twenty dogs met serologic criteria for either symptomatic (16 dogs) or asymptomatic (4 dogs) infection caused by Leptospira interrogans Australis serogroup. Seven of 16 symptomatic dogs died or were euthanized and 9/16 recovered. Systemic inflammatory response syndrome (SIRS) was observed in 9/16 dogs. The presence of SIRS did not affect prognosis (P = .357). C-reactive protein (CRP) and haptoglobin (Hpt) concentrations were altered in all symptomatic dogs, but results did not differ significantly between survivors and nonsurvivors (P = .08 and P = .055, respectively). Conversely, the CRP to Hpt ratio (CRP/Hpt) was significantly increased in nonsurvivors. Disseminated intravascular coagulation (DIC) was diagnosed in 7/16 dogs. DIC did not significantly affect outcome (P = .126). Multiple organ involvement was present with renal failure in 16/16, liver damage in 12/16, cardiac damage in 11/16, and muscular damage in 8/16 dogs. CONCLUSIONS AND CLINICAL IMPORTANCE: Among the evaluated clinicopathologic biomarkers, serum albumin, cardiac troponin I, CRP/Hpt, urinary albumin, and urinary total protein to creatinine ratio were found to predict outcome and warrant evaluation in larger prospective studies.  相似文献   

Genetic parameters for milk,growth, and reproductive traits in Guzerá cattle under tropical conditions     

Brito  Laís Costa  Peixoto  Maria Gabriela Campolina Diniz  Carrara  Eula Regina  Fonseca e Silva  Fabyano  Ventura  Henrique Torres  Bruneli  Frank Angelo Tomita  Lopes  Paulo Sávio 《Tropical animal health and production》2020,52(5):2251-2257

Tropical Animal Health and Production - This study aimed to estimate the genetic parameters of milk (305-day milk yield (MY305)), growth (weaning weight (WW), yearling weight (YW), and weight at...  相似文献   

Genotype-environment interaction for productive traits of Holstein cows in Brazil described by reaction norms     

Santos  Jarbas Corrêa  Malhado  Carlos Henrique Mendes  Cobuci  Jaime Araújo  de Rezende  Marcos Paulo Gonçalves  Carneiro  Paulo Luiz Souza 《Tropical animal health and production》2020,52(5):2425-2432

Tropical Animal Health and Production - Brazil is the world’s fourth largest milk producer; this activity extends throughout the national territory, with productions of approximate 34 billion...  相似文献   

Injectable eprinomectin for cattle: Tick efficacy and pharmacokinetics     

Cristiano Grisi do Nascimento  Gabrielle Bragaglia  Sandra Barioni Toma  Viviane de Souza Magalhães  Yara Peluso Cid  Fabio Barbour Scott 《Journal of veterinary pharmacology and therapeutics》2020,43(2):171-178

The aims of the present study were to evaluate the pharmacokinetic profile and efficacy of eprinomectin (EPM) against Rhipicephalus microplus in cattle of a new injectable form of EPM (Voss Performa®). The product was administered subcutaneously at a dose of 200 μg EPM/kg, in a single dose. The efficacy of EPM against R. microplus in cattle was evaluated through field and stall tests. Studies were performed to estimate the pharmacokinetic parameters of EPM with the purpose of better understanding the kinetics of the formulation. The formulation was effective in controlling R. microplus in both naturally and artificially infested cattle, providing efficacy greater than 95%. The results of pharmacokinetic study were C_max of 47.15 ± 22.20 ng/ml, T_max of 1.33 ± 0.492 days, T_1/2 of 2.96 ± 1.212 days, AUC_0–t of 228.08 ± 57.30 ng day ml⁻¹, and AUC_0-∞ of 240.50 ± 58.44 ng day ml⁻¹. Therefore, the new injectable EPM formulation becomes an important alternative for the control of cattle tick in Brazil.  相似文献   

BMP-15 activity on in vitro development of collared peccary (Pecari tajacu Linnaeus, 1758) preantral follicles     

Henrique A. N. Gomes  Lívia B. Campos  Érica C. G. Praxedes  Moacir F. Oliveira  Alexsandra F. Pereira  Alexandre R. Silva  Márcia V. A. Saraiva 《Reproduction in domestic animals》2020,55(8):958-964

This study investigated the effects of BMP-15 on the in vitro development of preantral follicles of collared peccaries. Ovarian fragments were cultured for 1 or 6 days in Tissue Culture Medium 199 (TCM199⁺) supplemented with BMP-15 at rates of 0, 1, 25 or 50 ng/ml. The fragments were analysed histologically by evaluating follicular morphology, activation and growth as well as the potential for proliferation of granulosa cells. Our results show the addition of 25 ng/ml BMP-15 in the medium provided the greatest percentage of normal follicles (79.67% ± 0.69) when compared to other treatments (p < .05); however, this result is similar to 1 ng/ml BMP-15 (74.00% ± 1.90, p > .05). Moreover, 25 and 50 ng/ml of BMP-15 promoted follicular activation. BMP-15 supplements did not affect oocyte and follicular growth. All concentrations of BMP-15 increased the number of nucleolus organizer regions (NORs) after 1 day of culture when compared to fresh fragments or the control samples (p < .05). However, at the end of the experiment, the number of NORs in follicles cultured in all treatments was higher than that observed in the fresh control (sample taken prior to culturing) (p > .05). In summary, the addition of 25 ng/ml BMP-15 to the culture medium of collared peccary preantral follicles maintained a high number of morphologically healthy follicles and stimulated the activation of primordial follicles after 6 days in culture.  相似文献   

Estimation of (co)variance components for birth weight in Nellore cattle using alternative data editing criteria     

Luiz Eduardo Cruz dos Santos Correia  Ricardo António da Silva Faria  Matheus Henrique Vargas de Oliveira  Rusbel Raúl Aspilcueta Borquis  Rogério Abdallah Curi  Josineudson Augusto II de Vasconcelos Silva 《Reproduction in domestic animals》2020,55(10):1355-1361

The aim of this study was to estimate the (co)variance components and breeding values for birthweight (BW) in Nellore cattle by considering or not identical weights that exhibit a high frequency within the contemporary group (CG). A total of 175,258 BW records of Nellore cattle born between 2002 and 2018 were used. The CG was formed by farm, year of birth, sex and feeding regime at birth. CGs with more than 16% of identical BW values were eliminated, generating a data file called BWd. Another file was created without removing these animals (BWt). A mixed linear model was used for statistical analysis, which included fixed and random effects. In both data files analysed, single-trait analysis was performed by Bayesian inference. The mean direct and maternal heritability for BW and the correlation between direct and maternal effects were 0.27, 0.07 and −0.07 for BWt, respectively, and 0.30, 0.093 and −0.07 for BWd. This method should affect the estimation of genetic merits of animals for BW, providing greater safety in the choice of sires.  相似文献   

Use of oxytocin to attain cervical dilation for transcervical embryo transfer in sheep     

Vanessa M. B. dos Santos  Pedro Henrique N. Pinto  Mario Felipe A. Balaro  Juliana D. R. Santos  Augusto R. Taira  Caroline G. do Espirito Santo  Fernanda M. Gonçalves  Jeferson F. da Fonseca  Felipe Z. Brandão 《Reproduction in domestic animals》2020,55(10):1446-1454

The aim of this work was to determine whether a cervical dilation protocol (CDP) composed of only oxytocin can be used to perform transcervical (non-surgical) embryo transfer in sheep (NSET) without affecting the viability of the corpus luteum (CL). Likewise, we evaluated whether a cervical transposing test with a Hegar dilator (CT Hegar test), performed at oestrous time, could be used to screen ewes for NSET (greater or lower chances to transpose the cervix). For that, oestrous and ovulation synchronization was performed in 25 Santa Inês ewes to induce the dioestrous condition. Animals went through the following CDP in a crossover design: E + OX, oestradiol benzoate (100 µg intravenously [IV]) and oxytocin (100 IU IV); OX, oxytocin (100 IU IV); and SAL, saline solution (IV). Using a Hegar dilator, cervical transposing attempts were performed at oestrous (D0) and dioestrous time (D8). The viability of the CL (morphology, luteal blood flow and progesterone values) was evaluated by ultrasonography (colour Doppler and B-mode) and by serum progesterone measurement from D7 to D13. The cervical transposing rate was lower for the SAL group (64%; 16/25; p < .05) and did not differ between the E + OX (88%; 22/25, p > .05) and OX (84%; 21/25, p > .05) groups. No treatment affected the CL viability. The CT Hegar test showed a high sensitivity (85.7%–93.3%), satisfactory accuracy (72%–84%), low false-negative rate (6.7%–14.6%), but high false-positive rate (46%–66.7%). In conclusion, a CDP protocol composed exclusively of oxytocin can lead to good cervical transposing rates and does not affect the viability of the CL. In addition, a screening test (CT Hegar) performed at oestrus can identify ewes for which cervical transposing will likely not occur at NSET.  相似文献   

Efficacy of oral sarolaner against Lynxacarus radovskyi in naturally infested cats     

Diefrey R. Campos  Jssica K. O. Chaves  Rayane C. P. Assis  Júlio I. Fernandes  Fabio B. Scott 《Veterinary dermatology》2020,31(5):355-e92

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Detection of hepatitis E virus RNA in rats caught in pig farms from Northern Italy     

Luca De Sabato  Giovanni Ianiro  Marina Monini  Alessia De Lucia  Fabio Ostanello  Ilaria Di Bartolo 《Zoonoses and public health》2020,67(1):62-69

Hepatitis E virus (HEV) strains belonging to the Orthohepevirus genus are divided into four species (A–D). HEV strains included in the Orthohepevirus A species infect humans and several other mammals. Among them, the HEV‐3 and HEV‐4 genotypes are zoonotic and infect both humans and animals, of which, pigs and wild boar are the main reservoirs. Viruses belonging to the Orthohepevirus C species (HEV‐C) have been considered to infect rats of different species and carnivores. Recently, two studies reported the detection of HEV‐C1 (rat HEV) RNA in immunocompromised and immunocompetent patients, suggesting a possible transmission of rat HEV to humans. The role of rats and mice as reservoir of HEV and the potential zoonotic transmission is still poorly known and deserves further investigation. To this purpose, in this study, the presence of HEV RNA was investigated in the intestinal contents and liver samples from 47 Black rats (Rattus rattus) and 21 House mice (Mus musculus) captured in four pig farms in Northern Italy. The presence of both Orthohepevirus A and C was investigated by the real‐rime RT‐PCR specific for HEV‐1 to HEV‐4 genotypes of Orthohepevirus A species and by a broad spectrum hemi‐nested RT‐PCR capable of detecting different HEV species including rat HEV. The intestinal content from two Black rats resulted positive for HEV‐C1 RNA and for HEV‐3 RNA, respectively. None of the House mice was HEV RNA positive. Sequence analyses confirmed the detection of HEV‐C1, genotype G1 and HEV‐3 subtype e. The viral strain HEV‐3e detected in the rat was identical to swine HEV strains detected in the same farm. Liver samples were negative for the detection of either rat HEV or HEV‐3.  相似文献   

Pedology-based management class establishment: a study case in Brazilian coffee crops     

Gonçalves  Mariana Gabriele Marcolino  Avalos  Fabio Arnaldo Pomar  dos Reis  Josimar Vieira  Costa  Milton Verdade  Silva  Sérgio Henrique Godinho  Poggere  Giovana Clarice  Curi  Nilton  de Menezes  Michele Duarte 《Precision Agriculture》2022,23(3):1027-1050

Precision Agriculture - This work proposes an approach for establishing coffee management classes mainly supported by pedological information (soil survey) and land parcels, taking into account...  相似文献