Local orbital forcing of antarctic climate change during the last interglacial     

SJ Kim  TJ Crowley  A Stossel 《Science (New York, N.Y.)》1998,280(5364):728-730

During the last interglacial, Antarctic climate changed before that of the Northern Hemisphere. Large local changes in precession forcing could have produced this pattern if there were a rectified response in sea ice cover. Results from a coupled sea ice-ocean general circulation model supported this hypothesis when it was tested for three intervals around the last interglacial. Such a mechanism may play an important role in contributing to phase offsets between Northern and Southern Hemisphere climate change for other time intervals.  相似文献   

Ectoparasitic dermatitis in free-ranging swamp wallabies (Wallabia bicolor) in New South Wales   总被引：1，自引：1，他引：0  

TJ Portas  A Crowley  J Hufschmid 《Australian veterinary journal》2009,87(4):160-162

We report extensive dermatological lesions in three, free-ranging, adult, male swamp wallabies ( Wallabia bicolor ), presented to Taronga Western Plains Zoo wildlife hospital. All three animals were moderately infested with the louse species Heterodoxus ualabati , and two were concurrently infested with a previously undescribed sarcoptiform mite of the genus Diabolicoptes . Histological changes included moderate to marked compact hyperkeratosis, focal deep pyoderma and superficial dermatophytosis. Mild to moderate hyperplastic perivascular and periadnexal dermatitis with marked superficial and follicular hyperkeratosis was evident in the skin of the inguinal region and lateral thigh of the two wallabies infested with the Diabolicoptes species. This is the first report of ectoparasitic dermatitis in free-ranging swamp wallabies and the first report of mites of the genus Diabolicoptes from a macropodid.  相似文献   

Leukotrienes Affect Secretory Function of Ovarian Cells In Vitro*     

AJ Korzekwa  TJ Acosta  M Miklewicz  K Okuda  SH Lee  DJ Skarzynski 《Reproduction in domestic animals》2010,45(6):e288-e296

The aim of this study was to determine which cells are the source of production and target for leukotriene (LTs) action within the bovine ovary. Luteal (CL, days 14–16 of the oestrous cycle), steroidogenic cells (LSC) and endothelial cells (LEC) of the bovine corpus luteum (CL), and granulosa cells (GC) were isolated enzymatically, cultured in a monolayer and incubated with LTC₄, LTB₄, Azelastine (an antagonist of LTC₄) or Dapsone (an antagonist of LTB₄). Then cells were collected for determination of mRNA expression for LT receptors (LTRs) and 5‐lipoxygenase (5‐LO) by real time RT‐PCR, and media were collected for determination of prostaglandin (PG)E₂, F_2α, progesterone (P4; LSC only), endothelin‐1 (ET‐1; LEC only) and 17‐β oestradiol (E2; GC only). The greatest mRNA expression for LTR‐II and 5‐LO were found in LEC, whereas LTR‐I mRNA expression did not differ among cell types. The level of PGE₂ increased after LTs treatment in each type of ovarian cell, excluding LTC₄ treatment in LEC. The secretion of PGF_2α was also increased by LTs, but decreased after LTB₄ treatment of LSC. In GC cultures, both LTs stimulated E2 secretion; in LEC cultures, LTB₄ stimulated whereas LTC₄ inhibited P4 secretion; in LEC cultures, LTC₄ stimulated but LTB₄ inhibited ET‐1 secretion. The results show that LTs are produced locally and are involved in PGs production/secretion in all examined cells (LSC, LEC and GC) of bovine ovary. Leukotriene treatment modulate secretion of E2, by GC, P4 by LSC and ET‐1 by LEC, which indicates that LTs are involved in regulation of ovarian secretory functions.  相似文献   

Expression and localization of BCRP,MRP1 and MRP2 in intestines,liver and kidney in horse     

E. TYDÉN  H. BJŐRNSTRŐM  H. TJÄLVE  P. LARSSON 《Journal of veterinary pharmacology and therapeutics》2010,33(4):332-340

Tydén, E., Bj?rnstr?m, H., Tjälve, H., Larsson, P. Expression and localization of BCRP, MRP1 and MRP2 in intestines, liver and kidney in horse. J. vet. Pharmacol. Therap. doi: 10.1111/j.1365‐2885.2009.01140.x. The gene and protein expression and the cellular localization of the ABC transport proteins breast cancer resistance protein (BCRP), multidrug resistance‐associated protein 1 (MRP1) and multidrug resistance‐associated protein 2 (MRP2) have been examined in the intestines, liver and kidney in horse. High gene and protein expression of BCRP and MRP2 were found in the small intestines, with cellular localization in the apical membranes of the enterocytes. In the liver, MRP2 was present in the bile canalicular membranes of the hepatocytes, whereas BCRP was localized in the cytoplasm of hepatocytes in the peripheral parts of the liver lobuli. In the kidney both BCRP and MRP2 were predominantly present in the distal tubuli and in the loops of Henle. In most tissues, the gene and protein expression of MRP1 were much lower than for BCRP and MRP2. Immunostaining of MRP1 was detectable only in the intestines and with localization in the cytoplasm of enterocytes in the caecum and colon and in the cells of serous acini of Brunner’s glands in the duodenum and the upper jejunum. The latter cells were also stained for BCRP, but not for MRP2. Many drugs used in horse are substrates for one or more of the ABC transport proteins. These transporters may therefore have important functions for oral bioavailability, distribution and excretion of substrate compounds in horse.  相似文献   

Some Factors Influencing the Period of Blossoming of Apples and Plums.     

R. G. Hatton  N. H. Grubb 《The Journal of Horticultural Science and Biotechnology》2013,88(3):210-215

Summary

Appropriate conditions for analysing fructans in the storage roots of field-grown asparagus using matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry (MALDI-TOF MS) were investigated. High resolution and ionisation were achieved when lyophilised and ground storage root powders were extracted twice with 1.0 ml distilled and deionised hot water (90°C), supplemented with 1.0 ml of 100% (v/v) ethanol, concentrated to approx. 1.0 ml, and mixed with 10 g l^–1 2,5-dihydroxybenzoic acid (DHB) at 1:1 (v/v) before loading on a sample slide for MALDI-TOF MS, which was performed in the linear positive ion mode at a laser intensity of 15 kV. The mass spectral profiles showed that the degree of polymerisation (DP) of fructans ranged from three-to-21 in storage roots collected in the Winter.When different amounts of -cyclodextrin were added to each sample, a linear positive relationship was observed between the amount of

-cyclodextrin and the relative positive ion intensity. With -cyclodextrin as an internal standard, fructan profiles were compared between Summer- and Winter-collected asparagus storage root samples. Furthermore, the fructan profiles of three different types of storage root of different colours (i.e., milky-white, yellow, or dark-brown) were also examined. Fructan contents were always higher in the Winter-collected samples than in those collected in the Summer, regardless of the DP. However, samples from the different coloured roots showed variable fructan profiles, depending on the DP. These results indicate that fructan analysis using MALDI-TOF MS would be useful for examining the dynamics of carbohydrate metabolism in asparagus storage roots because of its high degree of accuracy and its simplicity.  相似文献   

The Behaviour of Certain Pears on Various Quince Rootstocks.     

R. G. Hatton 《The Journal of Horticultural Science and Biotechnology》2013,88(2):216-233

Summary

A model for describing the modification of soil and air temperature by nonwoven polypropylene has been developed. Such a model takes into account the first two harmonics of the Fourier series determined from the normalized data of soil and surface temperature. The numerical model predicts with accuracy the soil thermal regime for hourly and daily intervals throughout the crop production cycles of Chinese cabbage (Brassica campestris ssp. pekinensis), lettuce (Lactuca sativa), table beet (Beta vulgaris) and spinach (Spinacia oleracea). Furthermore, the model proposed by Parton (1984) has been modified to estimate the surface temperature based on data of temperature measured at 2.m height, biomass and global solar radiation flux density incident on the crop grown under nonwoven polypropylene conditions.  相似文献   

A longitudinal study of veterinary students and recent graduates: 3. Perceptions of veterinary education   总被引：1，自引：1，他引：0  

TJ HEATH  A. LANYON  M. LYNCH-BLOSSE 《Australian veterinary journal》1996,74(4):301-304

Objective To examine the attitudes and opinions on veterinary education at the beginning and end of the veterinary course, and after graduation.
Design Longitudinal study.
Population Students – 154 in all – who began studying veterinary science at The University of Queensland in 1985 and 1986.
Procedure Questionnaires were completed in the first and fifth year of the course and in the second year after graduation. The data were analysed using the SAS System for Windows.
Results When they entered the course, the students were looking forward more to learning about animals than about basic sciences. At fifth year and after graduation most believed that more emphasis should have been placed on all facets of their education except the basic sciences. It may be difficult to increase this emphasis without placing undue pressure on the students, although more than half of the fifth year students and graduates agreed that there is much in the curriculum that is not needed by a practising veterinarian. Only one-third or less agreed that veterinarians are well equipped to practise veterinary science immediately they graduate. There was no relationship between the level of agreement with this statement, and the academic grades obtained.
Conclusions A majority of veterinary graduates do not believe that they are well equipped to practice immediately they graduate. They believe that more emphasis should have been placed on most facets of their education, but, conversely, that there is much in the curriculum that is not needed by a practising veterinarian.  相似文献   

The effect of monensin on the chemotactic function of bovine neutrophils     

KA STEPHENSON  IJ LEAN  TJ O'MEARA 《Australian veterinary journal》1996,74(4):315-317

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Surgical management of refractory nasal aspergillosis using iodine cadexomer dressings in three dogs          下载免费PDF全文

TJ Preston  GL Hosgood  AEH Paul 《Australian veterinary journal》2016,94(11):405-410

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Alphaherpesvirus‐associated disease in greater bilbies (Macrotis lagotis)          下载免费PDF全文

AS Besier  TJ Mahony  M Crockford  JL Gravel  TF Chapman  MA O'Dea 《Australian veterinary journal》2016,94(6):208-212

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