Effects of orchidectomy on bone metabolism in beagle dogs   总被引：5，自引：0，他引：5  

Fukuda S  Iida H 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2000,62(1):69-73

The effects of orchidectomy on bone metabolism in male beagle dogs were examined using twelve 2-year-old dogs that were orchidectomized. The dogs' bilateral iliac bones, double-labeled with tetracycline and calcein for the histomorphometry, were obtained from three dogs prior to orchidectomy and at 3, 6, 9, and 12 months afterwards. The serum biochemical constituents related to bone metabolism were examined before and every month after orchidectomy. Between 1 and 6 months after orchidectomy, the value of serum testosterone decreased (1 month), while the levels of parathyroid hormone, calcitonin, total calcium, osteocalcin, and alkaline phosphatase activity increased significantly, indicating a high bone turnover. The mean trabecular thickness and the fraction of labeled osteoid surface decreased significantly 3 months after orchidectomy, but other histomorphometric parameters were unchanged. In the period 7-12 months after orchidectomy, the parathyroid hormone level increased ever and above that of the first 6-month period, while the levels of calcitonin, osteocalcin, alkaline phosphatase activity, and phosphorus decreased. The bone volume, mean trabecular thickness, and the fraction of labeled trabecular surface decreased significantly compared with the pre-orchidectomy values. These findings indicate an imbalance in bone metabolism (i.e. bone resorption > bone formation). These results indicate that a loss of bone volume accompanied the fall in sex hormone levels following orchidectomy and suggest that the orchidectomized dog is available as an animal model for studying osteoporosis caused by hypogonadism and the decline of sex functions in men.  相似文献   

Plasma levels of the chemokine RANTES in macaque monkeys infected with pathogenic and non-pathogenic SIV/HIV-1 chimeric viruses at an early stage of infection     

Kwofie TB  Haga T  Iida T  Hayami M  Miura T 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2000,62(12):1311-1312

Plasma levels of the chemokine RANTES were examined in monkeys infected with either a pathogenic simian and human immunodeficiency chimeric virus (SHIV) or a non-pathogenic SHIV to determine whether RANTES levels were related to the pathogenicity of the virus, the plasma viral load, or the kinetics of CD4+ T-cells. In the results no significant correlation was found between the RANTES kinetics and changes in the CD4+ T-cell numbers nor the plasma viral loads in any of the monkeys, although a transient decrease of the RANTES level was observed in the pathogenic virus-infected monkeys. At least, the plasma RANTES level can not be used as an index of the pathogenicity of the virus at the early stage of infection.  相似文献   

Seroepidemiological survey of lymphocytic choriomeningitis virus in wild house mouse (Mus musculus) in Yokohama Port, Japan.     

C Morita  Y Matsuura  E Kawashima  S Takahashi  J Kawaguchi  S Iida  T Yamanaka  W Jitsukawa 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》1991,53(2):219-222

From 1985 to 1989, a total of 129 mice was captured from 7 piers of Yokohama port. Of these, 9 (7.0%) were positive to lymphocytic choriomeningitis virus (LCMV) antigen in indirect fluorescence antibody test. Six out of 31 mice (19.4%) in 1985 and 3 out of 23 mice (13.0%) captured in 1986 were positive. All the mice (74) captured in 1988 and 1989 were negative. Although 7 out of 17 mice (41.2%) in Osanbashi-Shinko pier and 2 out of 23 (8.7%) in Honmoku pier were positive in 1985 and 1986, all mice captured in other piers were negative. This is the first report detecting LCMV antibody in wild house mice in Japan.  相似文献   

Malignant seminoma with systemic metastases in a dog     

Takiguchi M  Iida T  Kudo T  Hashimoto A 《The Journal of small animal practice》2001,42(7):360-362

A three-year-old male crossbred dog was presented with multiple cutaneous nodules on the dorsum. Unilateral testicular enlargement ensued. Histopathological examination of testicular tissue and the skin lesions revealed a malignant seminoma. Despite the initiation of adjuvant chemotherapy, the dog died three months later due to systemic metastases of the seminoma to the skin, scrotum, eyes, liver, kidney and peritoneum.  相似文献   

TRIPLE‐PHASE HELICAL COMPUTED TOMOGRAPHY IN DOGS WITH HEPATIC MASSES     

Kenji Kutara  Mamiko Seki  Chieko Ishikawa  Manabu Sakai  Yumiko Kagawa  Gentoku Iida  Kumiko Ishigaki  Kenji Teshima  Kazuya Edamura  Tomohiro Nakayama  Kazushi Asano 《Veterinary radiology & ultrasound》2014,55(1):7-15

The purpose of this study was to determine the utility of triple‐phase helical computed tomography (CT) for differentiating canine hepatic masses. Seventy dogs with hepatic masses underwent triple‐phase CT followed by surgical removal of the hepatic masses. Triple‐phase helical CT scans for each dog included precontrast, arterial phase, portal venous phase, and delayed phase studies. The removed hepatic masses were histopathologically classified as hepatocellular carcinoma (n = 47), nodular hyperplasia (n = 14), and hepatic metastatic tumors (n = 9) in dogs. Of the 47 hepatocellular carcinomas, the most common CT findings included a heterogeneous pattern with hyper‐, iso‐, and hypoenhancement in both the arterial and portal venous phases (40/47, 85.1%). Of the 14 nodular hyperplasias, the most common CT findings were a homogeneous pattern with hyper‐ and isoenhancement in both the portal venous and delayed phases (13/14, 92.9%). Of nine hepatic metastatic tumors, the most common CT findings included a homogeneous hypoenhancement pattern in both the arterial and portal venous phases (8/9, 88.9%). In addition, 5 (55.6%) showed homogeneous hypoenhancement patterns in the delayed phase. Findings from our study indicated that triple‐phase CT is a useful tool for preoperative differentiation of hepatocellular carcinoma, nodular hyperplasia, and hepatic metastatic tumors in dogs.  相似文献   

Changes in wood temperature under high-speed friction     

Ryuichi Iida  Tadashi Ohtani  Takahisa Nakai  Koji Adachi 《Journal of Wood Science》2014,60(5):313-320

Thermal effects at the surface of a sample wood specimen while it is rubbed by reduction with a metal disk rotating at high speed are investigated. The results provide fundamental data for the development of new surface processing methods. The results of high-speed friction tests showed that the wood surface developed high-temperature regions due to the effect of friction heat, and deformed tissue was observed at the wood surface in the region that experienced the rubbing action. The thermal effects extended to a deep range in the deformed region by reduction due to different fiber inclination angles, both parallel and normal to the friction surface. The thermal effects from the rubbed conditions of the reduction and feed speed also extended deeply into the region deformed by reduction, although the thermal effect was decreased at higher feed speed. From the results of these friction tests, the change in wood temperature is described unambiguously by factors related to pressure on the friction surface.  相似文献   

Seasonal characteristics of surface water quality in the wastewater catchment system of an urbanizing basin     

Masaomi Kimura  Keigo Noda  Tatsuya Makino  Hijiri Yamagata  Somphasith Douangsavanh  Keoduangchai Keokhamphui  Hiromasa Hamada  Masashi Kiguchi  Toshiaki Iida  Kazuo Oki 《Paddy and Water Environment》2018,16(3):519-531

Vientiane, Lao PDR, has been subject to extensive and ongoing urbanization plans, including development of natural marshes and residentialization of paddy fields into suburban areas, despite natural marshes playing a vital role in treating wastewater from urban areas. Therefore, it is important to understand the current situation regarding the nutrient balance in these natural wastewater treatment systems to predict future conditions and design appropriate measures against water quality deterioration. However, limited data are available in Vientiane on the hydrological characteristics of water and nutrient runoff that flow into marshes through drainage canals. In this study, we conducted a periodic survey of drainage canals and Mak Hiao River in the wastewater catchment system surrounding Vientiane during the rainy and dry seasons. We monitored the discharge of surface water at 21 observation sites and analyzed water quality of nitrogen, phosphorus, and total organic carbon. These observations revealed that the concentrations of dissolved nitrogen and phosphorus were significantly higher at sites in urban areas, followed by sites in the main river basin and those in agricultural areas. Dissolved nitrogen and phosphorus concentrations varied with runoff discharge, especially in urban and river basin sites, with lower concentrations in the rainy season and higher concentrations in the dry season. On the other hand, we found no significant differences between the rainy and dry seasons in nutrient concentrations in the agricultural basin. Finally, we proposed measures to counteract the deterioration of water quality during dry seasons and simulated the impact of these measures.  相似文献