Subtotal Intracapsular Prostatectomy Results in Normal Dogs     

JOHN J. ROBERTSON DVM  M. JOSEPH BOJRAB DVM  MS  PhD  DiplomateACVS 《Veterinary surgery : VS》1984,13(1):6-10

Subtotal intracapsular prostatectomy was performed on five normal dogs. All dogs were maintained for 60 days postoperatively. No urinary abnormalities were noted following surgery with the exception of transient urinary incontinence in one dog that lasted for 7 days. Upon termination of the study, the prostatic urethra had reepithelized in all dogs where a dorsal strip of epithelium was left in place during surgery.  相似文献   

Flea Control: An Overview of Treatment Concepts for North America   总被引：2，自引：0，他引：2  

JOHN M. MACDONALD 《Veterinary dermatology》1995,6(3):121-130

Résumé— L'approche d'un contrôle anti puces souligne Pimportance de la communication entre le vétérinaire et le propriétaire d'un animal de compagnie, communication qui implique la connaissance de chaque cas de figure individuel. Une revue des antiparasitaires usuels est brièvement présentée incluant les principes actifs et leur classification. Les concepts de mise en place d'un programme de contrôle anti puces qui sont présentés incluent aussi bien les aspects de contrôle des puces à l'intérieur des habitations et dans le milieu exérieur, que les produits et méthodes utilisées pour traiter l'animal. Les produits les plus récents utilisés dans la lutte antipuces sont présentés, comme les régulateurs de croissance des insectes, les inhibiteurs de croissance des insectes, les traitements utilisant des nématodes, et les composés à base de borate. [MacDon-ald, J. M. Flea control: an overview of treatment concepts for North America (Contrôle antipuces: revue des concepts de traitement en Amérique du Nord). Resumen— El enfoque al control de pulgas pone de manifiesto la importancia de la interrelación entre el veterinario y el propietario del animal, siendo necesario un conocimiento de las condiciones especiales en casos individuales. Se presenta una breve revisión de los parasiticidas más comunes, con un listado de los compuestos activos y su clasificación. Se presentan los principios para el diseño de un programa de control de pulgas, incluyendo el control dentro y fuera de la vivienda, asi como productos y métodos para tratar el animal. Se revisan los productos más recientes utilizados para el control de pulgas como reguladores del crecimiento de insectos, reguladores del desarrollo de insectos, tratamiento de nemátodos y compuestos de borato. [MacDonald, J. M. Flea control: an overview of treatment concepts for North America (Control de pulgas: un repaso a los principios sobre tratamiento en Norte-América). Abstract— The approach to flea control emphasizes the importance of interrelationships between veterinarian and pet owner requiring knowledge of the unique environment of individual cases. A review of common parasiticides is briefly presented listing active ingredients and their classification. Concepts of developing a flea control program are presented that include aspects of inside and outside flea control as well as products and methods used to treat the pet. Newer products used in flea control are reviewed including insect growth regulators, insect development inhibitors, nematode treatment and borate compounds.  相似文献   

Magnetic Motor Evoked Potentials for Assessing Spinal Cord Integrity in Dogs with Intervertebral Disc Disease     

ANNE M. SYLVESTRE dvm  dvsc  JOANNE R. COCKSHUTT dvm  dipiomate acvs  JOANE M. PARENT dvm  mvsc  dipiomate acvim  JOHN D. BROOKE phd  DAVID L. HOLMBERG dvm  mvsc  dipiomate acvs  GARY D. PARTLOW phd 《Veterinary surgery : VS》1993,22(1):5-10

Magnetically elicited transcranial motor evoked potentials (MEPs) were studied in 37 dogs with type 1 intervertebral disc (IVD) disease. The waveforms were recorded from both cranial tibial muscles before and after surgery. The latencies and amplitudes obtained were compared to those of a control population (n = 14). MEPs were recordable in all dogs with mild or no neurologic deficits, but they were recordable in only 50% of ambulatory dogs that were severely ataxic. MEPs could not be elicited from nonambulatory dogs. There was a significant attenuation of the amplitudes in all clinical cases, even if the dogs demonstrated back pain alone. Significantly prolonged latencies were associated with neurologic deficits. MEPs were not good predictors of neurologic recovery. The responses obtained from the side where the disc material was found were not different from those recorded from the opposite side. MEPs were very sensitive to lesions of the spinal cord, as indicated by the significant changes in the waves in patients with mild or no neurologic deficits and in the loss of response in dogs that still demonstrated purposeful movement. Neurologic exams provided more accurate diagnoses and prognoses than did MEPs in dogs with IVD disease.  相似文献   

Chlorhexidine Diacetate and Povidone-iodine Cytotoxicity to Canine Embryonic Fibroblasts and Staphylococcus aureus     

ISIS R. SANCHEZ dvm  ms    KENNETH E. NUSBAUM dvm  PhD    STEVEN F. SWAIM dvm  ms    ANNE S. HALE dvm    RALPH A. HENDERSON dvm  ms  Diplomateacvs  JOHN A. McGUIRE PhD 《Veterinary surgery : VS》1988,17(4):182-185

Chlorhexidine diacetate and povidone-iodine were evaluated for fibroblast toxicity on a primary line of canine embryonic fibroblasts, and for bactericidal efficacy against Staphylococcus aureus. The cultured fibroblasts or S. aureus were exposed for 30 minutes to incremental dilutions of 0.5 and 0.0005% chlorhexidine diacetate, 5.0 to 0.05% povidone-iodine, or physiologic buffered saline as a control. To determine survival, fibroblasts were trypsinized and counted; S. aureus colonies were counted on brain-heart infusion agar. Survival for both groups was expressed by calculating the number of living cells in test dilutions as a percentage of the number in control cultures. Fibroblast survival occurred at chlorhexidine concentrations less than 0.013% and at povidone-iodine concentrations less than 0.5% (p less than 0.05). Significant S. aureus survival (p less than 0.05) was noted at chlorhexidine concentrations less than 0.05% and povidone-iodine concentrations less than 1.0%. These data showed that all bactericidal concentrations of chlorhexidine diacetate and povidone-iodine were lethal to canine embryonic fibroblasts in vitro, whereas non-lethal concentrations allowed significant bacterial survival.  相似文献   

Concentrations of thyroid hormones and iodothyronine binding proteins in serum of the koala (Phascolarctos cinereus)     

VERONICA J. LAWSON  REA J. CURTIS†  VALDO P. MICHELANGELI‡  JAN R. STOCKIGT†  FRANK N. CARRICK  JOHN W. BARLOW† § 《Australian veterinary journal》1996,74(1):55-58

Objective To examine circulating total and free thyroid hormone (T₃ and T₄) concentrations, determine serum iodothyronine binding characteristics and estimate thyroid stimulating hormone (TSH) activity in sera of coastal and inland koalas.
Design A prospective study.
Procedure Koala serum T₃ and T₄ were measured by radioimmunoassay. T₄ binding parameters were determined by radioligand binding and electrophoresis. Koala TSH values were determined by bioassay.
Results Mean total T₄ concentrations were 3.2 ± 2.1 nM although values were significantly higher in inland-dwelling females in comparison to coastal-dwelling males. Free T₄ was 3.3 ± 2.1 pM. Total and free T₃ were 0.4 ± 0.2 nM and 1.4 ± 0.9 pM respectively, although these values were at the lower end of the assay detection limit and should be viewed with reservation. Electrophoresis of [¹²⁵I]-T₄-labelled serum revealed only two proteins of electrophoretic mobility similar to human transthyretin (TTR) and albumin. Scatchard analysis of T₄ binding to serum gave a curvilinear plot, which could be resolved into two binding sites with affinities identical to that of TTR and albumin but both of low concentration. The bioactivity of the TSH present in the sera was measured using a cell line (JP09) transfected with the human TSH receptor. The mean level of stimulation found in the sera corresponded to a bovine TSH activity of less than 10 mU/L.
Conclusion These results suggest that the serum concentrations of free and total thyroid hormones in koalas are low compared to other marsupials and very low compared to eutherian mammals. The mechanism of maintenance of euthyroidism in this species remains to be determined.  相似文献   

Osteochondral Defects of the Lateral Trochlear Ridge of the Distal Femur of the Horse Clinical, Radiographic, and Pathological Examination and Results of Surgical Treatment     

JOHN R. PASCOE BVSc    ROY R. POOL DVM  PhD    JOHN D. WHEAT DVM  DiplomateACVS  TIMOTHY R. O'BRIEN DVM  PhD  DiplomateACVR 《Veterinary surgery : VS》1984,13(2):99-110

Osteochondral defects of the lateral trochlear ridge of the distal femur were identified in 15 joints of 10 horses. Lesions were bilateral in five horses and unilateral in five horses. Thirteen of these 15 defects were treated by curettage through a craniolateral femoropatellar arthrotomy. Subcutaneous seroma formation and partial skin dehiscence occurred in nine stifles. Lameness attributable to the stifle joint was no longer apparent at 6 and 12 months after surgery. The normal subchondral bony contour of the lateral trochlear ridge was altered in all joints after surgery. The subchondral bone was uniformly increased in density in all joints, and six lateral trochlear ridges had small focal radiolucent regions within the subchondral bone, which suggested that complete removal of the original lesion had not been achieved. Healing of the surgical site between 2 weeks and 14 months was evaluated in four joints. Granulation tissue from mesenchymal elements in subchondral marrow spaces gradually filled the defects with fibrocartilage.  相似文献   

Holding Power of Orthopedic Screws in Equine Third Metacarpal and Metatarsal Bones: Part I. Foal Bone     

JOHN V. YOVICH BSc  BVMS    A. S. TURNER BVSc  MS  DiplomateACVS  F. W. SMITH BSME  MSME  PhD 《Veterinary surgery : VS》1985,14(3):221-229

The holding power of orthopedic screws in the third metacarpal and metatarsal cadaver bones of foals that were aged from 1 to 14 days was tested. Comparative trials between screws inserted at the same site in contralateral bones from the same foal were performed to compare the holding power of 5.5 mm cortical and 6.5 mm cancellous screws in the metaphysis, and the holding power of 5.5 and 4.5 mm cortical screws in the diaphysis. A MTS servohydraulic tensile testing machine was used to perform screw pullouts at a displacement rate of 19 mm/sec. There was no significant difference between maximum holding power of 5.5 mm cortical screws and 6.5 mm cancellous screws in the metaphysis when expressed as kg per mm of bone width at the screw insertion site (p = 0.097) or as kg per mm of screw thread engaged in the bone (p = 0.17). There was no significant difference in holding power of 5.5 and 6.5 mm screws in the proximal versus distal metaphysis (p = 0.10). The 5.5 mm screws had significantly greater holding power than the 4.5 mm screws in the diaphysis (p = 0.0097). Fixation failure at screw pullout was always due to bone shear. In internal fixation in foal bone, the 5.5 mm screws may be a suitable alternative to 6.5 mm screws in the metaphysis. Use of 5.5 mm rather than 4.5 mm screws is recommended in the diaphysis because of greater holding power.  相似文献   

Dangerous dogs     

JOHN BOWER 《The Journal of small animal practice》1992,33(6):255-256

  相似文献   

Kirschner Wire Fixation of Lateral Humeral Condylar Fractures in Small Dogs     

DON MORSHEAD DVM  JOHN E. STAMBAUGH VMD  PhD  DiplomateACVS 《Veterinary surgery : VS》1984,13(1):1-5

Successful treatment of humeral condylar fractures requires accurate reduction and rigid internal fixation. Lag screw fixation is the traditional method of repair for these fractures. An alternative method using Kirschner wire fixation was used to repair humeral condylar fractures in eight small dogs. Long-term follow-up was available for seven dogs: all were reported to have normal limb function.  相似文献   

Quelques aspects biochimiques de la physiologie des radis (Raphanus sativus L.) traités par la simazine.*     

JOHN L. GNANARETHINAM 《Weed Research》1975,15(3):143-148

L'action de la simazine ne peut être réduite au seul fait de l'inhibition de la photosynthése. Chez le radis (Raphanus tativus L.). la simazine a provoqué d'abord une baisse considérable du traux des glucides dans le limbe des plantes trailées. Cette diminution a affecté e principalement le glucose et le fructose ct plus encore le saccharose, cependant qu'apparaissait du glycérol. Dans la racine, les osides et les oses ont augmenté pendant les 3 jours qui suivirent le traitement et ont diminué ensuite rapidement. Dans le pétiole, l'évolution a éié intermédiaire. Au stade deux feuilles, les p plantes ayant été misese en lumiére continue aussitôt aprés le traitement, l'augmentation initiale des reserves glucidiques s'est à nouveau produite. Au contraire, dans l'obscurité continue, la diminution des glucides a été analogue chez les plantes témoins et chez les plantes traitées. Quant à la chlorophylle. la teneur a augmenté jusqu'au 4e jour aprés le traitement, puis elle a diminué ensuite en même temps que le saccharose tandis qu'apparaissaient des signes de chlorose. Il est suggéré QUE la disparition du saccharose pourrait provenir, soit d'une inhibition dc sa formation par manque d'ATP photosynthétique-2, soit de son hydrolyse, ce qui expliquerait l'augmentation initiale des oses. Biochemische Cesichispunkle zur Physiologie von Rettichen (Raphanus sativus L.) nach Simazinbekandllug I. Produktion von Gluciden Die Wirkung von Simazin beschränkt sich nicht auf die Hemmung der Photosynthese. In Rettichen (Raphanus sativus L.) verursachte Simazin am Anfang in den Blättern eine beträchtliche Abnahme an Gluciden. Diese Abnahme betraf hauptsáUhlich Glucose und Fructose und noch mehr die Saccharose; dabei trat gleichzeitig Glycerin auf. In den ersten drei Tagen nach der Behandlung nahmen in der Wurzel freie Zucker (Osen) und glykosidisch gebundene Zucker (Oside) zu, danach nahmen sie rasch ab. Im Biatlstiel lag die Produktion dazwischen. Wenn die Pflanzen im 2-Blattstadium unmittelbar nach der Behandlung Dauerlicht ausgesetzt wurden, wiederholte sich die anfängliche Zunahme an ‘glucidartigen’ Reservestoffen. Befanden sich aber die Pflanzen in ständiger Dunkelheit, entsprach die Abnahme an Gluciden der von den Kontrollen. Der Chlorophyllgehalt nahm his zum vierten Tag nach der Behandlung zu und sank dann gleichzeitig mit der Saccharose ab. wobei Anzeichen von Chlorose auftraten. Es liegt die Vermutung nahe, dass die Abnahme der Saccharose entweder mit der Hemmung der Saccharosebildung durch Mangel an ‘Photosynlhcsc-2′-ATP, oder durch ihre Hydrulyse zusammenhánget, was auch die anfängliche Zunahme an Osen erklären würde. Some biochemical aspects of the physiology of radishes (Raphanus sativus L.) treated with simazine I. Production of glucides The action of simazine is not limited to the inhibition of photosynthesis. In radishes (Raphanus sativus L.) simazine caused a considerable initial reduction in the amount of glucides in the leaf blades of treated plants. This reduction applied principally to glucose and fructose and still more to saccharose, while at the same time glycerol appeared. In the root, oses and osides increased over the first 3 days following treatment and then decreased rapidly. In the petiole, production was intermediate. At the two-leaf stage, when the plants were subjected to continuous light immediately after treatment, the initial increase in glucidic reserves was repeated. In continuous darkness, however, the decrease in glucides was similar in both controls and treated plants. The content of chlorophyll increased until the fourth day after treatment then it decreased at the same time as saccharose, while signs of chlorosis appeared. It is suggested that the disappearance of saccharose might be due either to its formation being inhibited through lack of ATP ‘photo-synthetic-2′. or to its hydrolysis, which would explain the initial increase in the oses.  相似文献