An epizootic of subcutaneous tumors associated with subgroup A avian leukosis/sarcoma virus in young layer chickens     

Ono M  Tsukamoto K  Tanimura N  Haritani M  Kimura KM  Suzuki G  Okuda Y  Sato S 《Avian diseases》2004,48(4):940-946

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Adjuvant effects of sugar cane extracts (SCE) in chickens     

El-Abasy M  Motobu M  Sameshima T  Koge K  Onodera T  Hirota Y 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2003,65(1):117-119

The effects of sugar cane extracts (SCE) on immune responses in chickens were studied. Two- or 10-month-old chickens orally administered SCE (500 mg/kg/day), for 3 consecutive days before immunized with sheep red blood cells, Brucella abortus and Salmonella Enteritidis organisms, showed significantly increased and prolonged antibody responses to these antigens, compared to control chickens without SCE. Furthermore, chickens orally administered SCE also revealed enhanced delayed type hypersensitivity responses to human gamma globulin. These results indicated that SCE has immunostimulating and adjuvant effects in chickens.  相似文献   

Quadrigeminal cisterna arachnoid cyst diagnosed by MRI in five dogs     

Kitagawa M  Kanayama K  Sakai T 《Australian veterinary journal》2003,81(6):340-343

Arachnoid cysts of the quadrigeminal cisterna are infratentorial cystic lesions located between the collicular plate and the incisural notch of the tentorium. We report here five cases of quadrigeminal cisterna arachnoid cysts in dogs. In this study, four of the five dogs were male, three showed signs of seizures, and one dog was over 10 years of age. In two of the dogs, cysts were discovered incidentally. In previous reports, most intracranial arachnoid cysts were located in the quadrigeminal cisterna. The presence of cysts should be considered in toy breeds presenting for seizures or ataxia.  相似文献   

Cystic meningioma in a dog     

Kitagawa M  Kanayama K  Sakai T 《The Journal of small animal practice》2002,43(6):272-274

There have been few reports of the occurrence of, and treatment methods for, cystic meningioma in the dog. This report describes a case in a Maltese which presented with a three-month history of seizures. Cystic meningioma was diagnosed by magnetic resonance imaging using contrast medium (gadoteridol) enhanced images. Attempted surgical removal of the mass was successful, and the outcome following surgery was good.  相似文献   

Characterization of Staphylococcus aureus strains isolated from bovine mastitis in Japan     

Nagase N  Shimizu A  Kawano J  Yamashita K  Yoshimura H  Ishimaru M  Kojima A 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2002,64(12):1169-1172

Fifty-three strains of Staphylococcus aureus isolated from cows affected with mastitis from 21 prefectures in Japan were characterized by phenotypic and genotypic methods. Thirty-three (62.3%) strains showed biotype K-beta+CV:A, coagulase type VI, and sensitivity to bovine phages of group III or IV. These 33 strains could be subdivided into two groups on the basis of the production of staphylococcal enterotoxins (SEs) and on toxic shock syndrome toxin-1 (TSST-1). By pulsed-field gel electrophoresis, the 16 SEC- and TSST-1-producing strains showed similar patterns that differed by only a few fragments, suggesting that they were genetically closely related. Fifteen of 17 non SEC-producing strains which did not produce any other SEs and TSST-1 were genetically different from the SEC-producing strains and showed genetic diversity.  相似文献   

Sequence comparison of the dopamine receptor D4 exon III repetitive region in several species of the order Carnivora     

Inoue-Murayama M  Matsuura N  Murayama Y  Tsubota T  Iwasaki T  Kitagawa H  Ito S 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2002,64(8):747-749

It was previously demonstrated that the dog dopamine receptor D4 (DRD4) gene is polymorphic in terms of the repeat number and/or order of 39- and 12-bp sequences located in the third exon. To examine whether or not the repetitive region is present in other species of the order Carnivora, the homologous region of DRD4 genes were sequenced in the gray wolf, raccoon dog, Asiatic black bear, common raccoon and domestic cat. In the family Canidae, the wolf had an identical sequence to that of the dog 447b allele, and a repetitive sequence similar to the dog DRD4 was also recognized in the raccoon dog. On the other hand, no obvious repeated structure was observed in the sequences of the bear, raccoon and cat.  相似文献   

Plasma concentrations of an angiotensin-converting enzyme inhibitor, benazepril, and its active metabolite, benazeprilat, after repeated administrations of benazepril in dogs with experimental kidney impairment     

Kitagawa H  Eguchi T  Kitoh K  Ohba Y  Kondo M  Nakano M  Sasaki Y 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2000,62(2):179-185

In order to examine the safety of an angiotensin-converting enzyme (ACE) inhibitor in dogs with impaired renal excretion route, benazepril was administered orally, and plasma concentrations of benazeprilat, the active metabolite of benazepril, were determined in dogs with renal mass reduction (1/4th kidney) created by right-side nephrectomy and ligation of branches of the left renal arteries. Five dogs were administered benazepril orally at a given dose (0.5 mg/kg body weight) and 4 other dogs received 20 times that dose (10 mg/kg body weight) once daily for 15 consecutive days before (intact kidney period) and after (1/4th kidney period) creation of kidney impairment. Six control dogs received surgical treatment, but no drug. After creating a 1/4th kidney, plasma urea nitrogen and creatinine concentrations increased to approximately 30 mg/dl and 2.0 mg/dl, respectively, and renal plasma flow and glomerular filtration rate decreased to 37% and 30% of pre-treatment values, respectively. However, these parameters did not change significantly during the 1/4th kidney period both in the 0.5 mg/kg and 10 mg/kg groups. In the 0.5 mg/kg group, plasma benazeprilat concentrations increased to approximately 20 ng/ml to 340 ng/ml 2 hr after each administration, and there were no significant differences between the plasma benazeprilat concentrations during the intact and 1/4th kidney periods. In the 10 mg/kg group, plasma benazeprilat concentrations varied in the individual dog, but did not increase with the days of administration, and were not significantly different on each administration day between the intact and 1/4th kidney periods in either dose group. The AUCs(0-24) of plasma benazeprilat concentrations determined on the 15th administration day were not different between the intact and 1/4th kidney periods in dogs of either dose group. Plasma ACE activities decreased after drug administration in dogs of both groups. Benazepril seemed to have a high safety, and the adjustment of dosage regimen might not be needed in dogs with mild to moderate renal function impairment because the drug was excreted both from the kidneys and liver.  相似文献   

Active-oxygen involvement in canine NK-mediated cytotoxicity     

Nariai 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2000,62(4):457-460

We examined the relationship between natural killer (NK) cell-mediated cytotoxicity, the produced active-oxygen and cytotoxic factor (CF) release in co-culturing canine NK cells with tumor cells (CL-1 target cells). In co-culturing, the adding of n-propyl gallate (active-oxide scavenger) removed the produced active-oxygen, which inhibited NK cell-mediated cytotoxicity and the CF release. Moreover, adding of this agent inhibited the tyrosine phosphorylation of NK intracellular protein which observed in co-culturing. Therefore, the active-oxygen produced from canine NK cells are thought to relate the signal transduction in NK-mediated cytotoxicity.  相似文献   

Retinomotor responses of juvenile bluefin tuna Thunnus thynnus     

Shukei Masuma  Gunzo Kawamura  Nobuhiro Tezuka  Masahiko Koiso  Kenji Namba 《Fisheries Science》2001,67(2):228-231

SUMMARY: In bluefin tuna culture, a high mortality of juveniles is caused by bumping into the tank and net-pen walls at dawn. This bumping can possibly be attributed to visually disoriented behavior of the fish. To examine this possibility, the authors carried out retinomotor response experiments with juvenile bluefin tuna (50.7–96.8 mm total length, at which they were transferred from a indoor tank to a sea net-pen) and measured ambient light intensity at the culture site at dawn. The light intensity at which the transition from scotopic to photopic vision takes place was 7.52 lx and the time taken by the transition was 15 min. At dawn, the ambient light intensity rapidly increased from scotopic light intensity level and attained photopic light intensity level in 10 min. This incompatibility of the retinal adaptation with the change in the ambient light intensity could cause the visual disorientation of the fish. It is therefore possible that the visually disoriented juveniles cannot control their high power swimming and thus bump into the walls at dawn.  相似文献   

A scanning electron microscopic study on the architecture of lymph vessels and intranodal lymph pathways of lymph nodes in pigs     

N Hoshi  Y Hashimoto  H Kitagawa  Y Kon  N Kudo 《The Japanese journal of veterinary research》1988,36(1):1-14

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