In vitro inhibitory effect of trichostatin A on canine grade 3 mast cell tumor     

Nagamine MK  Sanches DS  Pinello KC  Torres LN  Mennecier G  Latorre AO  Fukumasu H  Dagli ML 《Veterinary research communications》2011,35(6):391-399

Mast cell tumor (MCT) is one of the most prevalent neoplasms that affect skin and soft tissue in dogs. Because mast cell tumors present a great variety of clinical appearance and behavior, their treatment becomes a challenge. Trichostatin A (TSA), an antifungal antibiotic, has shown inhibitory effects on the proliferation and induction of apoptosis in various types of cancer cells. In order to evaluate the potential of trichostatin A as a therapeutic drug, cells of grade 3 MCT were cultured and treated with concentrations of 1 nM to 400 nM of TSA. MTT assay and trypan blue exclusion assays were performed to estimate cell growth and cell viability, and cell cycle analysis was evaluated. TSA treatment showed a reduction in numbers of viable cells and an increase of cell death by apoptosis. The cell cycle analysis showed an increase of hypodiploid cells and a reduction of G0/G1 and G2/M –phases. According to these results, trichostatin A may be an interesting potential chemotherapeutic agent for the treatment of canine MCT.  相似文献   

Combinations of cactus pear with different roughage sources on the production,chemical composition,and milk fatty acid profile of F1 Holstein/Zebu cows     

Soares  Camila  Rocha Júnior  Vicente Ribeiro  Monção  Flávio Pinto  Borges  Lucas Daniel Alcântara  Caldeira  Luciana Albuquerque  Costa  Natanael Mendes  Ruas  José Reinaldo Mendes  Rigueira  João Paulo Sampaio  da Cunha Siqueira Carvalho  Cinara  de Sales  Eleuza Clarete Junqueira  de Assis Pires  Daniel Ananias  Chamone  Julieta Maria Alencar 《Tropical animal health and production》2020,52(5):2567-2576

Tropical Animal Health and Production - The qualities of food, mainly of animal origin, have always been of concern to consumers. It is known that the composition of animals’ diets can...  相似文献   

Serum biochemistry of the Arrau turtle (Podocnemis expansa): Frozen analyte stability and the effects of long-term storage     

Fabricio Camargo  Nadjanaira B. Abrão  Thawanne D. Queiroz  Emmanuel Arhnold  Luciana B. M. Araújo  Danieli B. Martins 《Veterinary clinical pathology / American Society for Veterinary Clinical Pathology》2020,49(1):42-47

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Impacts of the nitrogen application on productivity and nutrients concentrations of the corn-Congo grass intercropping system in the dry season     

Karina Batista  Alessandra Aparecida Giacomini  Luciana Gerdes  Waldssimiler Teixeira De Mattos  Ivani Pozar Otsuk 《Acta Agriculturae Scandinavica, Section B - Plant Soil Science》2013,63(7):567-577

ABSTRACT

The corn-grass intercropping system began to be used in the dry season, as it provides increased straw production for the no-tillage system. However, corn and grass are plants demanding in nitrogen. The corn cultivated in the dry season is called out-of-season corn in Brazil. The objective of this study was to evaluate the productivity and nutrients concentrations of out-of-season corn and Congo-grass intercropped in the no-tillage system, as a function of the nitrogen rates applied in sidedressing. The treatments were four nitrogen rates, 0, 30, 60 and 90?kg?ha^?1. The experimental design was randomised complete blocks with four replicates. The experimental period corresponded to the harvests of 2015 and 2016. There were evaluated: corn grain yield, dry mass production and nutrient concentration in the shoots of the plants intercropped. The evaluations were carried out at the physiological maturity stage of the corn and at the time of desiccation of the grass. Nitrogen increased grain yield and dry mass production of the plants intercropped. Nitrogen maximised the magnesium concentration in out-of-season corn and the nitrogen, calcium, magnesium and sulphur concentrations in Congo grass. Excess nitrogen promoted reduction of the phosphorus in the Corn-Congo grass intercropping system in the dry season.  相似文献   

Trichoderma as a biological agent of Fusarium oxysporum species complex and Vigna unguiculata growth promoter     

do Amaral  Ana Cl&#;udia Ten&#;rio  de Holanda Cavalcanti Maciel  Mar&#;lia  Machado  Alexandre Reis  de Oliveira  Luciana Gon&#;alves  Lima  Cristiano Souza  da Costa  Antonio F&#;lix  de Oliveira  Neiva Tinti 《European journal of plant pathology / European Foundation for Plant Pathology》2022,163(4):875-890

European Journal of Plant Pathology - This study aimed to evaluate the potential antagonistic role of Trichoderma in the control of Fusarium isolates belonging to the Fusarium oxysporum species...  相似文献   

Molecular and morphological characterization of Golestan (Iran) olive ecotypes provides evidence for the presence of promising genotypes   总被引：1，自引：1，他引：0  

Soraya Mousavi  Mehdi Hosseini Mazinani  Kazem Arzani  Abbas Ydollahi  Saverio Pandolfi  Luciana Baldoni  Roberto Mariotti 《Genetic Resources and Crop Evolution》2014,61(4):775-785

Unidentified olive plants naturally grow in the Golestan province of Iran, on different soils and under climates spanning from sub-temperate to desert conditions, represented by single trees or groups of few trees. We collected samples from representative sites and analyzed them by simple sequence repeat markers in order to determine their identity and their relationships to prominent Iranian and Mediterranean reference cultivars. Population structure analysis separated these ecotypes from Mediterranean and, surprisingly, from all Iranian cultivars, the parentage test excluded their direct contribution as candidate parents or offspring of cultivars, and they also showed a high level of admixture. Their differentiation from cultivated olives may be attributed to different factors: they could represent wild plants or could derive from natural dissemination of ancestral cultivated trees. Their survival up to now may be due to the fact that most of them are grown on sacred sites such as necropolis. Anyhow, the adaptation to strong environmental stresses, and their fruit size and oil content make the olive Golestan ecotypes a valuable source of genetic variation previously uncharacterized and currently threatened with extinction.  相似文献   

Is community-based forest management more effective than protected areas?: A comparison of land use/land cover change in two neighboring study areas of the Central Yucatan Peninsula,Mexico     

Edward A. Ellis  Luciana Porter-Bolland 《Forest Ecology and Management》2008

The importance of the role of local community forestry institutions towards forest conservation is exemplified through a comparison of two adjacent areas within the Central Yucatan Peninsular Region (CYPR) in which Land-Use Cover Change (LUCC) analyses were conducted. We also used logistic regression analyses to examine key environmental, socioeconomic and institutional drivers associated with deforestation. One of the areas, La Montaña (LM) at Hopelchen, Campeche, is part of the northern section and buffer zone of the Calakmul Biosphere Reserve (CBR) as well as part of the Mesoamerican Biological Corridor. LM is an agricultural forest frontier region economically dependent on productive activities. The other study, Zona Maya (ZM), found at the municipality of Felipe Carrillo Puerto in Quintana is characterized by having developed community-based forestry enterprises with world wide recognition. In addition, the major tourism industry in nearby Cancun and Riviera Maya provide an important source of off-farm labor and temporary migration. Results show contrasting annual deforestation rates among the two study areas, being greater in the Campeche site (0.7% from 2000 to 2005) compared to Quintana Roo (−0.002% from 2000 to 2004). Logistic regression results show that the occurrence of land clearing at LM is significantly related to demographic variables as well as soil-environment types and conservation status did not reveal to relate to LUCC processes at all. At Quintana Roo, despite twice the population density, population variables at large did not strongly correlate to forest clearing. Rather forest conservation or maintenance was shown to be influenced by local community forestry institutions and a landscape zoning provided by larger management goals from the part of the communities. Greater availability of wage labor for the prominent tourism economy may also reflect a lesser dependence on agriculture and contribute to the much lower deforestation rate. Nonetheless, results show that community forest management can play an effective role in forest conservation. We argue for a regional land use management approach as a conservation strategy in which local inhabitants are considered key actors.  相似文献   

Selection efficiency of high inorganic phosphorus-low stachyose lines from soybean breeding populations of different genetic backgrounds     

Luciano M. Jaureguy  M. Luciana Rosso  Katy M. Rainey 《Journal of Crop Improvement》2017,31(1):25-38

Reducing the antinutritional components of soybean (Glycine max) seed is necessary for producing animal feed with increased metabolizable energy and nutrient availability. The objective of this study was to evaluate marker-assisted and phenotypic selection for the high inorganic phosphorus (Pi) and low stachyose traits controlled by the Lpa and MIPS1 mutations in six breeding populations. Phenotypic selection for low phytate individuals carrying Lpa mutations using Pi was reliable, but the assay should include parental genotypes to construct thresholds before performing selections, as the effect of Lpa on Pi depends on genetic background. Phenotypic selection for low phytate individuals carrying MIPS1 using Pi should be complemented with sugar data because selection based solely on Pi may be inefficient, as this trait is not environmentally stable in MIPS1 germplasm. Marker-assisted selection for simple sequence repeat (SSR) linked to Lpa2 (Satt527, Satt561) depended on the pedigree of the population suggesting that perfect markers (e.g., single nucleotide polymorphism) should become the molecular tool for screening a large number of progenies with high efficiency.  相似文献   

Nutritional planning for Nellore heifers post-weaning to conception at 15 months of age: performance and nutritional,metabolic, and reproductive responses     

de Almeida  Daniel Mageste  Marcondes  Marcos Inácio  Rennó  Luciana Navajas  Pereira Silva  Luiz Henrique  Martins  Leandro Soares  Marquez  David Esteban Contreras  Castaño Villadiego  Faider Alberto  Velez Saldarriaga  Felipe  Franco  Julian David Castaño  Moreno  Deilen Paff Sotelo  de Moura  Felipe Henrique  Paulino  Mário Fonseca 《Tropical animal health and production》2019,51(1):79-87

Tropical Animal Health and Production - The objective of this study was to evaluate the effects of strategic supplementation in the dry period and dry/rainy transition period on the performance and...  相似文献   

Canine ovariectomy by hybrid or total natural orifice transluminal endoscopic surgery: technical feasibility study and pain assessment     

Marcella Teixeira Linhares  Joo Pedro Scussel Feranti  Gabriela Pesamosca Coradini  Letícia Reginato Martins  Arthur Rodrigues Martins  Vanessa Zanchi Sarturi  Felipe Baldissarella Gavioli  Marco Augusto Machado Silva  Michelli Westphal de Ataíde  Luciana Gonalves Teixeira  Maurício Veloso Brun 《Veterinary surgery : VS》2019,48(Z1):O74-O82

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